Ingrid Glimelius

Ingrid Glimelius

Affiliated to Research
Visiting address: Maria Aspmans gata 30A, 17164 Solna
Postal address: K2 Medicin, Solna, K2 KEP Ekström Smedby, 171 77 Stockholm

About me

  • I am a professor in Oncology and a medical oncologist working with mainly
    lymphoma- and testicular cancer patients at Uppsala University Hospital and
    do research at both Karolinska Institutet and Uppsala University,
    https://www.igp.uu.se/research/cancer-precision-medicine/ingrid-glimelius/. I
    have been collaborating with Karin E Smedby and been affiliated to the Cancer
    Epidemiology group at the Division of Clinical Epidemiology, Karolinska
    Institutet since long. In addition to my clinical work I perform clinical
    phase I-III studies and epidemiological studies. I supervise PHD-students and
    post docs and I teach both medical students and senior physicians. I have
    been awarded Senior Clinical Investigator Cancer Award from the Swedish
    Cancer Society in spring 2019.
    I have research collaborations with both Uppsala University, Ahlborg
    University, Mayo Clinic in the US. The Nordic lymphoma group.
    I participate and include patients in clinical trial, phase I, phase II and
    phase III, mainly within the field of lymphoma and particularily mantle cell
    lymphoma. We introduce novel targeted drugs, explore immunotherapies and
    implement new disease monitoring tools.
    MD, Uppsala University 2001
    PHD, Uppsala University 2009, /Hodgkin lymphoma – an interplay between
    tumour cell and microenvironment/
    MD, specialist Internal Medicine 2011
    MD, specialist Oncology 2013
    Associate Professor in Oncology 2016
    Good Clinical Practice, Investigator Site Personnel ICH-GCP 2017
    Senior consultant, Oncology 2019
    Senior Clinical Investigator Award, the Swedish Cancer Society 2019-2025
    Senior lecturer since 2021
    Professor Uppsala University 2023

Research

  • My primary research interest is in malignant lymphomas, with a specific
    focus on Hodgkin lymphoma and Mantle cell lymphoma. In addition, I have an
    interest in Ovarian and Testicular cancer.
    *Mantle cell lymphoma (MCL)* is one of the lymphoma subtype that with
    combination chemotherapy still has a poor survival, although prognostic
    heterogeneity exists. Using epidemiological “real-world data” I
    investigate treatment selection and the prognostic implication of associated
    diseases. I am also national principal investigator for the *ENRICH*-trial: A
    randomized phase III study for elderly MCL patients with randomization
    between Rituximab-Ibrutinib AND Rituximab-chemotherapy (Bendamustine or CHOP)
    with the aim to test if a chemotherapy free concept can improve survival. I
    am also local PI for the *VALERIA* trial in Uppsala testing
    Lenalidomide-Venetoclax and Rituximab for relapsed/refractory mantle cell
    lymphoma patients. We started in year 2022 the *ALTAMIRA* trial that
    investigates a disease monitoring approch with minimal residual disease
    monitoring for elderly mantle cell lymphoma patients treated with
    acalabrutinib and rituximab.
    In addition, my research interests are in young cancer patients, with a
    specific focus on survivorship, particularly childbearing potential and
    long-term prognosis for *Hodgkin lymphoma patients, other lymphoma subtypes
    and testicular cancer*. I describe late adverse effects from both
    chemotherapy and radiotherapy. We have in collaboration with other researcher
    and specifically Caroline Weibull (https://ki.se/people/cardie [1]) published
    a series of publications regarding childbearing potential in Hodgkin lymphoma
    survivors (please see below).
    I also study other lymphatic malignancies, *testicular cancer* and *ovarian
    cancer* both regarding aetiology, prognosis and late-effects from treatment.
    [1] https://ki.se/people/cardie

Teaching

  • Teacher Medical School, Oncology, Uppsala University since year 2010
    Teacher research school in Epidemiology, Karolinska Institutet 2013-2014
    Steering committee National Research School in Oncology, NATION, since 2017
    Examiner for project-works in Medical School, Uppsala University since 2017

Articles

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Employments

  • Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2026

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