Inger Nennesmo

Publications
Public outreach and news

Articles

Article: JOURNAL OF NEUROLOGY. 2022;269(6):3037-3049

TBK1 haploinsufficiency results in changes in the K63-ubiquitination profiles in brain and fibroblasts from affected and presymptomatic mutation carriers.

Khoshnood B; Ullgren A; Laffita-Mesa J; Öijerstedt L; Patra K; Nennesmo I; Graff C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2021;297(6):101355

A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy.

Ygberg S; Akkuratov EE; Howard RJ; Taylan F; Jans DC; Mahato DR; Katz A; Kinoshita PF; Portal B; Nennesmo I; Lindskog M; Karlish SJD; Andersson M; Lindstrand A; Brismar H; Aperia A
Article: MOLECULAR PSYCHIATRY. 2021;26(10):5609-5619

Amyloid, tau, and astrocyte pathology in autosomal-dominant Alzheimer's disease variants: AβPParc and PSEN1DE9.

Lemoine L; Gillberg P-G; Bogdanovic N; Nennesmo I; Saint-Aubert L; Viitanen M; Graff C; Ingelsson M; Nordberg A
Article: MOLECULAR PSYCHIATRY. 2021;26(10):5833-5847

Astroglial tracer BU99008 detects multiple binding sites in Alzheimer's disease brain.

Kumar A; Koistinen NA; Malarte M-L; Nennesmo I; Ingelsson M; Ghetti B; Lemoine L; Nordberg A
Article: NEUROLOGY-GENETICS. 2021;7(2):e566

Novel Mutation m.10372A>G in MT-ND3 Causing Sensorimotor Axonal Polyneuropathy.

Bruhn H; Samuelsson K; Schober FA; Engvall M; Lesko N; Wibom R; Nennesmo I; Calvo-Garrido J; Press R; Stranneheim H; Freyer C; Wedell A; Wredenberg A
Article: MOVEMENT DISORDERS. 2021;36(2):508-514

A Novel Duplication in ATXN2 as Modifier for Spinocerebellar Ataxia 3 (SCA3) and C9ORF72-ALS.

Laffita-Mesa JM; Nennesmo I; Paucar M; Svenningsson P
Article: JOURNAL OF PEDIATRICS. 2021;228:240-251.e2

Clinical Presentation, Genetic Etiology, and Coenzyme Q10 Levels in 55 Children with Combined Enzyme Deficiencies of the Mitochondrial Respiratory Chain.

Naess K; Bruhn H; Stranneheim H; Freyer C; Wibom R; Mourier A; Engvall M; Nennesmo I; Lesko N; Wredenberg A; Wedell A; von Döbeln U
Article: JOURNAL OF WRIST SURGERY. 2020;9(6):481-486

Structural Changes in the Posterior Interosseous Nerve from Patients with Wrist Osteoarthritis and Asymptomatic Controls.

Swärd E; Nennesmo I; Wilcke M
Article: DIAGNOSTICS. 2020;10(11):E966-966

Neurogenic vs. Myogenic Origin of Acquired Muscle Paralysis in Intensive Care Unit (ICU) Patients: Evaluation of Different Diagnostic Methods.

Marrero HDJG; Stålberg EV; Cooray G; Corpeno Kalamgi R; Hedström Y; Bellander B-M; Nennesmo I; Larsson L
Article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020;38(1):42-49

Features of repeated muscle biopsies and phenotypes of monocytes in paired blood samples and clinical long-term response to treatment in patients with idiopathic inflammatory myopathy: a pilot study.

Tang Q; Gheorghe KR; Zhang X-M; Lindroos E; Alexanderson H; Wick C; Bruton M; Fernandes-Cerqueira C; Harris RA; Nennesmo I; Lundberg IE
Article: CLINICAL GENETICS. 2019;96(2):118-125

Early activating somatic PIK3CA mutations promote ectopic muscle development and upper limb overgrowth.

Frisk S; Taylan F; Blaszczyk I; Nennesmo I; Annerén G; Herm B; Stattin E-L; Zachariadis V; Lindstrand A; Tesi B; Laurell T; Nordgren A
Article: HUMAN MOLECULAR GENETICS. 2019;28(11):1919-1929

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24.

Hedberg-Oldfors C; Abramsson A; Osborn DPS; Danielsson O; Fazlinezhad A; Nilipour Y; Hübbert L; Nennesmo I; Visuttijai K; Bharj J; Petropoulou E; Shoreim A; Vona B; Ahangari N; López MD; Doosti M; Banote RK; Maroofian R; Edling M; Taherpour M; Zetterberg H; Karimiani EG; Oldfors A; Jamshidi Y
Article: FRONTIERS IN GENETICS. 2018;9:317

Pathological Study of a FMR1 Premutation Carrier With Progressive Supranuclear Palsy.

Paucar M; Nennesmo I; Svenningsson P
Article: HUMAN MOLECULAR GENETICS. 2017;26(13):2515-2525

A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma.

Siibak T; Clemente P; Bratic A; Bruhn H; Kauppila TES; Macao B; Schober FA; Lesko N; Wibom R; Naess K; Nennesmo I; Wedell A; Peter B; Freyer C; Falkenberg M; Wredenberg A
Article: NEUROMUSCULAR DISORDERS. 2017;27(7):627-630

Late-onset limb-girdle muscular dystrophy caused by GMPPB mutations.

Balcin H; Palmio J; Penttilä S; Nennesmo I; Lindfors M; Solders G; Udd B
Article: ORPHANET JOURNAL OF RARE DISEASES. 2017;12(1):73

Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model.

Tegelberg S; Tomašić N; Kallijärvi J; Purhonen J; Elmér E; Lindberg E; Nord DG; Soller M; Lesko N; Wedell A; Bruhn H; Freyer C; Stranneheim H; Wibom R; Nennesmo I; Wredenberg A; Eklund EA; Fellman V
Article: SCIENTIFIC REPORTS. 2017;7:45496

Cortical laminar tau deposits and activated astrocytes in Alzheimer's disease visualised by 3H-THK5117 and 3H-deprenyl autoradiography.

Lemoine L; Saint-Aubert L; Nennesmo I; Gillberg P-G; Nordberg A
Article: ALZHEIMERS & DEMENTIA. 2017;13(4):419-430

Amyloid tracers binding sites in autosomal dominant and sporadic Alzheimer's disease.

Ni R; Gillberg P-G; Bogdanovic N; Viitanen M; Myllykangas L; Nennesmo I; Långström B; Nordberg A
Article: JOURNAL OF HUMAN GENETICS. 2017;62(2):321-324

No common founder for C9orf72 expansion mutation in Sweden.

Chiang H-H; Forsell C; Lindström A-K; Lilius L; Thonberg H; Nennesmo I; Graff C
Article: ALZHEIMERS RESEARCH & THERAPY. 2016;8(1):30

Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device.

Eyjolfsdottir H; Eriksdotter M; Linderoth B; Lind G; Juliusson B; Kusk P; Almkvist O; Andreasen N; Blennow K; Ferreira D; Westman E; Nennesmo I; Karami A; Darreh-Shori T; Kadir A; Nordberg A; Sundström E; Wahlund L-O; Wall A; Wiberg M; Winblad B; Seiger Å; Wahlberg L; Almqvist P
Article: ARTHRITIS RESEARCH & THERAPY. 2016;18(1):136

Effects on muscle tissue remodeling and lipid metabolism in muscle tissue from adult patients with polymyositis or dermatomyositis treated with immunosuppressive agents.

Loell I; Raouf J; Chen Y-W; Shi R; Nennesmo I; Alexanderson H; Dastmalchi M; Nagaraju K; Korotkova M; Lundberg IE
Article: ALZHEIMER DISEASE & ASSOCIATED DISORDERS. 2016;30(2):178-182

Same Ages, Same Genes: Same Brains, Same Pathologies?: Dementia Timings, Co-Occurring Brain Pathologies, ApoE Genotypes in Identical and Fraternal Age-matched Twins at Autopsy.

Iacono D; Volkmann I; Nennesmo I; Pedersen NL; Fratiglioni L; Johansson B; Karlsson D; Winblad B; Gatz M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(12):4612-4624

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.

Albrecht I; Wick C; Hallgren Å; Tjärnlund A; Nagaraju K; Andrade F; Thompson K; Coley W; Phadke A; Diaz-Gallo L-M; Bottai M; Nennesmo I; Chemin K; Herrath J; Johansson K; Wikberg A; Ytterberg AJ; Zubarev RA; Danielsson O; Krystufkova O; Vencovsky J; Landegren N; Wahren-Herlenius M; Padyukov L; Kämpe O; Lundberg IE
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;97(5):761-768

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.

Kishita Y; Pajak A; Bolar NA; Marobbio CMT; Maffezzini C; Miniero DV; Monné M; Kohda M; Stranneheim H; Murayama K; Naess K; Lesko N; Bruhn H; Mourier A; Wibom R; Nennesmo I; Jespers A; Govaert P; Ohtake A; Van Laer L; Loeys BL; Freyer C; Palmieri F; Wredenberg A; Okazaki Y; Wedell A
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2015;74(11):1061-1070

Antemortem Prediction of Braak Stage.

Carlson JOE; Gatz M; Pedersen NL; Graff C; Nennesmo I; Lindström A-K; Gerritsen L
Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2015;3:40

Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue.

Lemoine L; Saint-Aubert L; Marutle A; Antoni G; Eriksson JP; Ghetti B; Okamura N; Nennesmo I; Gillberg P-G; Nordberg A
Article: ALZHEIMERS & DEMENTIA. 2015;11(1):40-50.e1-2-50

Resolution of inflammation is altered in Alzheimer's disease.

Wang X; Zhu M; Hjorth E; Cortés-Toro V; Eyjolfsdottir H; Graff C; Nennesmo I; Palmblad J; Eriksdotter M; Sambamurti K; Fitzgerald JM; Serhan CN; Granholm A-C; Schultzberg M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(1):204-210

Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease.

Varsani H; Charman SC; Li CK; Marie SKN; Amato AA; Banwell B; Bove KE; Corse AM; Emslie-Smith AM; Jacques TS; Lundberg IE; Minetti C; Nennesmo I; Rushing EJ; Sallum AME; Sewry C; Pilkington CA; Holton JL; Wedderburn LR; UK Juvenile Dermatomyositis Research Group
Article: BRAIN PATHOLOGY. 2014;24(4):317-333

Neuropathologic assessment of dementia markers in identical and fraternal twins.

Iacono D; Volkman I; Nennesmo I; Pedersen NL; Fratiglioni L; Johansson B; Karlsson D; Winblad B; Gatz M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2014;73(5):913-920

Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up.

Zong M; Dorph C; Dastmalchi M; Alexanderson H; Pieper J; Amoudruz P; Barbasso Helmers S; Nennesmo I; Malmström V; Lundberg IE
Article: JOURNAL OF ALZHEIMERS DISEASE. 2014;39(4):787-797

Alteration of thioredoxin and glutaredoxin in the progression of Alzheimer's disease.

Arodin L; Lamparter H; Karlsson H; Nennesmo I; Björnstedt M; Schröder J; Fernandes AP
Article: NEUROMUSCULAR DISORDERS. 2013;23(11):945-951

193rd ENMC International workshop Pathology diagnosis of idiopathic inflammatory myopathies 30 November - 2 December 2012, Naarden, The Netherlands.

De Bleecker JL; Lundberg IE; de Visser M; ENMC Myositis Muscle Biopsy Study Group
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2013;21(11):1260-1265

Novel progranulin mutations with reduced serum-progranulin levels in frontotemporal lobar degeneration.

Chiang H-H; Forsell C; Lilius L; Öijerstedt L; Thordardottir S; Shanmugarajan K; Westerlund M; Nennesmo I; Thonberg H; Graff C
Article: JOURNAL OF NEUROINFLAMMATION. 2013;10:90

³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain.

Marutle A; Gillberg P-G; Bergfors A; Yu W; Ni R; Nennesmo I; Voytenko L; Nordberg A
Article: HUMAN MUTATION. 2013;34(2):363-373

A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats.

van der Zee J; Gijselinck I; Dillen L; Van Langenhove T; Theuns J; Engelborghs S; Philtjens S; Vandenbulcke M; Sleegers K; Sieben A; Bäumer V; Maes G; Corsmit E; Borroni B; Padovani A; Archetti S; Perneczky R; Diehl-Schmid J; de Mendonça A; Miltenberger-Miltenyi G; Pereira S; Pimentel J; Nacmias B; Bagnoli S; Sorbi S; Graff C; Chiang H-H; Westerlund M; Sanchez-Valle R; Llado A; Gelpi E; Santana I; Almeida MR; Santiago B; Frisoni G; Zanetti O; Bonvicini C; Synofzik M; Maetzler W; Vom Hagen JM; Schöls L; Heneka MT; Jessen F; Matej R; Parobkova E; Kovacs GG; Ströbel T; Sarafov S; Tournev I; Jordanova A; Danek A; Arzberger T; Fabrizi GM; Testi S; Salmon E; Santens P; Martin J-J; Cras P; Vandenberghe R; De Deyn PP; Cruts M; Van Broeckhoven C; van der Zee J; Gijselinck I; Dillen L; Van Langenhove T; Theuns J; Philtjens S; Sleegers K; Bäumer V; Maes G; Corsmit E; Cruts M; Van Broeckhoven C; van der Zee J; Gijselinck I; Dillen L; Van Langenhove T; Philtjens S; Theuns J; Sleegers K; Bäumer V; Maes G; Cruts M; Van Broeckhoven C; Engelborghs S; De Deyn PP; Cras P; Engelborghs S; De Deyn PP; Vandenbulcke M; Vandenbulcke M; Borroni B; Padovani A; Archetti S; Perneczky R; Diehl-Schmid J; Synofzik M; Maetzler W; Müller Vom Hagen J; Schöls L; Synofzik M; Maetzler W; Müller Vom Hagen J; Schöls L; Heneka MT; Jessen F; Ramirez A; Kurzwelly D; Sachtleben C; Mairer W; de Mendonça A; Miltenberger-Miltenyi G; Pereira S; Firmo C; Pimentel J; Sanchez-Valle R; Llado A; Antonell A; Molinuevo J; Gelpi E; Graff C; Chiang H-H; Westerlund M; Graff C; Kinhult Ståhlbom A; Thonberg H; Nennesmo I; Börjesson-Hanson A; Nacmias B; Bagnoli S; Sorbi S; Bessi V; Piaceri I; Santana I; Santiago B; Santana I; Helena Ribeiro M; Rosário Almeida M; Oliveira C; Massano J; Garret C; Pires P; Frisoni G; Zanetti O; Bonvicini C; Sarafov S; Tournev I; Jordanova A; Tournev I; Kovacs GG; Ströbel T; Heneka MT; Jessen F; Ramirez A; Kurzwelly D; Sachtleben C; Mairer W; Jessen F; Matej R; Parobkova E; Danel A; Arzberger T; Maria Fabrizi G; Testi S; Ferrari S; Cavallaro T; Salmon E; Santens P; Cras P; European Early-Onset Dementia Consortium
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2012;20(8):897-904

Mutations in the mitochondrial tRNA Ser(AGY) gene are associated with deafness, retinal degeneration, myopathy and epilepsy.

Tuppen HAL; Naess K; Kennaway NG; Al-Dosary M; Lesko N; Yarham JW; Bruhn H; Wibom R; Nennesmo I; Weleber RG; Blakely EL; Taylor RW; McFarland R
Article: EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY. 2012;16(4):379-389

Phenotypic and genotypic variability in Alpers syndrome.

Sofou K; Moslemi A-R; Kollberg G; Bjarnadóttir I; Oldfors A; Nennesmo I; Holme E; Tulinius M; Darin N
Article: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE. 2012;5(2):201-207

Imaging astrocytosis with PET in Creutzfeldt-Jakob disease: case report with histopathological findings.

Engler H; Nennesmo I; Kumlien E; Gambini JP; Lundberg P; Savitcheva I; Långström B
Article: JIMD REPORTS. 2012;4:67-73

Complete Deletion of a POLG1 Allele in a Patient with Alpers Syndrome.

Naess K; Barbaro M; Bruhn H; Wibom R; Nennesmo I; von Döbeln U; Larsson N-G; Nemeth A; Lesko N
Article: BMC RESEARCH NOTES. 2011;4:476

Mutation screening of patients with Alzheimer disease identifies APP locus duplication in a Swedish patient.

Thonberg H; Fallström M; Björkström J; Schoumans J; Nennesmo I; Graff C
Article: BRAIN. 2011;134(Pt 4):1116-1126

Reduced C-afferent fibre density affects perceived pleasantness and empathy for touch.

Morrison I; Löken LS; Minde J; Wessberg J; Perini I; Nennesmo I; Olausson H
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2011;31(1):18-25

Higher proportion of fast-twitch (type II) muscle fibres in idiopathic inflammatory myopathies - evident in chronic but not in untreated newly diagnosed patients.

Loell I; Helmers SB; Dastmalchi M; Alexanderson H; Munters LA; Nennesmo I; Lindroos E; Borg K; Lundberg IE; Esbjörnsson M
Article: BRAIN. 2011;134(Pt 1):301-317

Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's disease.

Kadir A; Marutle A; Gonzalez D; Schöll M; Almkvist O; Mousavi M; Mustafiz T; Darreh-Shori T; Nennesmo I; Nordberg A
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2010;18(11):1202-1208

The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Aβ in different brain regions.

Keller L; Welander H; Chiang H-H; Tjernberg LO; Nennesmo I; Wallin AK; Graff C
Article: MUSCLE & NERVE. 2010;41(6):751-757

Bedside diagnosis of rippling muscle disease in CAV3 p.A46T mutation carriers.

Sundblom J; Stålberg E; Osterdahl M; Rücker F; Montelius M; Kalimo H; Nennesmo I; Islander G; Smits A; Dahl N; Melberg A
Article: NEUROMUSCULAR DISORDERS. 2010;20(3):198-203

Two novel mutations in thymidine kinase-2 cause early onset fatal encephalomyopathy and severe mtDNA depletion.

Lesko N; Naess K; Wibom R; Solaroli N; Nennesmo I; von Döbeln U; Karlsson A; Larsson N-G
Article: ACTA MYOLOGICA. 2009;28(3):91-93

Severe phenotype of a patient with autosomal recessive centronuclear myopathy due to a BIN1 mutation.

Mejaddam AY; Nennesmo I; Sejersen T
Article: JOURNAL OF IMMUNOLOGY. 2009;183(7):4792-4799

T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells.

Fasth AER; Dastmalchi M; Rahbar A; Salomonsson S; Pandya JM; Lindroos E; Nennesmo I; Malmberg K-J; Söderberg-Nauclér C; Trollmo C; Lundberg IE; Malmström V
Article: PLOS GENETICS. 2009;5(5):e1000499

Sensory ataxic neuropathy in golden retriever dogs is caused by a deletion in the mitochondrial tRNATyr gene.

Baranowska I; Jäderlund KH; Nennesmo I; Holmqvist E; Heidrich N; Larsson N-G; Andersson G; Wagner EGH; Hedhammar A; Wibom R; Andersson L
Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2009;80(2):188-195

A novel NGFB point mutation: a phenotype study of heterozygous patients.

Minde J; Andersson T; Fulford M; Aguirre M; Nennesmo I; Remahl IN; Svensson O; Holmberg M; Toolanen G; Solders G
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2009;16(1):48-53

Impairment of short-term memory and Korsakoff syndrome are common in AIDS patients with cytomegalovirus encephalitis.

Pirskanen-Matell R; Grützmeier S; Nennesmo I; Sandström E; Ehrnst A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2008;67(12):1670-1677

A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies.

Dastmalchi M; Grundtman C; Alexanderson H; Mavragani CP; Einarsdottir H; Helmers SB; Elvin K; Crow MK; Nennesmo I; Lundberg IE
Article: ALZHEIMERS & DEMENTIA. 2008;4(6):414-420

Progranulin mutation causes frontotemporal dementia in the Swedish Karolinska family.

Chiang H-H; Rosvall L; Brohede J; Axelman K; Björk BF; Nennesmo I; Robins T; Graff C
Article: JOURNAL OF INTERNAL MEDICINE. 2008;264(4):388-400

Central nervous system involvement in severe congenital neutropenia: neurological and neuropsychological abnormalities associated with specific HAX1 mutations.

Carlsson G; van't Hooft I; Melin M; Entesarian M; Laurencikas E; Nennesmo I; Trebińska A; Grzybowska E; Palmblad J; Dahl N; Nordenskjöld M; Fadeel B; Henter J-I
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2007;363(4):989-993

VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice.

Zheng C; Sköld MK; Li J; Nennesmo I; Fadeel B; Henter J-I
Article: ARTHRITIS & RHEUMATOLOGY. 2007;57(7):1192-1201

International consensus on a proposed score system for muscle biopsy evaluation in patients with juvenile dermatomyositis: a tool for potential use in clinical trials.

Wedderburn LR; Varsani H; Li CKC; Newton KR; Amato AA; Banwell B; Bove KE; Corse AM; Emslie-Smith A; Harding B; Hoogendijk J; Lundberg IE; Marie S; Minetti C; Nennesmo I; Rushing EJ; Sewry C; Charman SC; Pilkington CA; Holton JL; UK Juvenile Dermatomyositis Research Group
Article: ANNALS OF THE RHEUMATIC DISEASES. 2007;66(10):1276-1283

Limited effects of high-dose intravenous immunoglobulin (IVIG) treatment on molecular expression in muscle tissue of patients with inflammatory myopathies.

Barbasso Helmers S; Dastmalchi M; Alexanderson H; Nennesmo I; Esbjörnsson M; Lindvall B; Lundberg IE
Article: EXPERIMENTAL NEUROLOGY. 2006;202(2):373-380

Apolipoprotein E deficiency increased microglial activation/CCR3 expression and hippocampal damage in kainic acid exposed mice.

Duan R-S; Chen Z; Dou Y-C; Concha Quezada H; Nennesmo I; Adem A; Winblad B; Zhu J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2006;65(12):1565-1571

Signs of inflammation in both symptomatic and asymptomatic muscles from patients with polymyositis and dermatomyositis.

Dorph C; Englund P; Nennesmo I; Lundberg IE
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2006;65(8):758-768

POLG1 mutations associated with progressive encephalopathy in childhood.

Kollberg G; Moslemi A-R; Darin N; Nennesmo I; Bjarnadottir I; Uvebrant P; Holme E; Melberg A; Tulinius M; Oldfors A
Article: NEUROBIOLOGY OF AGING. 2005;26(5):597-606

Human monoclonal antibodies against amyloid-beta from healthy adults.

Geylis V; Kourilov V; Meiner Z; Nennesmo I; Bogdanovic N; Steinitz M
Article: DEVELOPMENTAL NEUROBIOLOGY. 2005;62(2):207-218

Increased microglial activation and astrogliosis after intranasal administration of kainic acid in C57BL/6 mice.

Chen Z; Duan R-S; Quezada HC; Mix E; Nennesmo I; Adem A; Winblad B; Zhu J
Article: JOURNAL OF NEUROIMMUNOLOGY. 2005;159(1-2):165-176

Dendritic cells in the cerebrospinal fluid and peripheral nerves in Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy.

Press R; Nennesmo I; Kouwenhoven M; Huang Y-M; Link H; Pashenkov M
Article: EXPERIMENTAL NEUROLOGY. 2004;190(2):486-494

Anti-cytokine autoantibodies in experimental autoimmune neuritis in Lewis rats.

Zhu W; Mix E; Nennesmo I; Adem A; Zhu J
Article: MUSCLE & NERVE. 2004;30(6):752-760

Familial insensitivity to pain (HSAN V) and a mutation in the NGFB gene. A neurophysiological and pathological study.

Minde J; Toolanen G; Andersson T; Nennesmo I; Remahl IN; Svensson O; Solders G
Article: ANNALS OF NEUROLOGY. 2004;56(4):564-567

Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.

Zheng C; Nennesmo I; Fadeel B; Henter J-I
Article: ACTA RADIOLOGICA. 2004;45(5):547-555

Detection of small implanted tumors growing during repeated magnetic resonance imaging of the rabbit liver: application of an interpretation model.

Thorstensen O; Isberg B; Jorulf H; Svahn U; Westman L; Venizelos N; Nennesmo I
Article: NEUROBIOLOGY OF DISEASE. 2004;16(3):630-637

CCR5 deficiency does not prevent P0 peptide 180-199 immunized mice from experimental autoimmune neuritis.

Duan R-S; Chen Z; Bao L; Quezada HC; Nennesmo I; Winblad B; Zhu J
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2004;63(2):120-128

Increased susceptibility to experimental autoimmune neuritis after upregulation of the autoreactive T cell response to peripheral myelin antigen in apolipoprotein E-deficient mice.

Yu S; Duan R-S; Chen Z; Quezada HC; Bao L; Nennesmo I; Zhu S-W; Winblad B; Ljunggren H-G; Zhu J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2003;76(1-3):55-68

Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients.

Gardner A; Johansson A; Wibom R; Nennesmo I; von Döbeln U; Hagenfeldt L; Hällström T
Article: MUSCLE & NERVE. 2003;27(4):442-448

CBA/J mice infected with Trypanosoma cruzi: an experimental model for inflammatory myopathies.

Andersson J; Englund P; Sunnemark D; Dahlstedt A; Westerblad H; Nennesmo I; Orn A; Lundberg IE
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2003;107(3):233-239

Alterations of rCBF and mitochondrial dysfunction in major depressive disorder: a case report.

Gardner A; Pagani M; Wibom R; Nennesmo I; Jacobsson H; Hällström T
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2003;30(1):85-95

Multitracer study with positron emission tomography in Creutzfeldt-Jakob disease.

Engler H; Lundberg PO; Ekbom K; Nennesmo I; Nilsson A; Bergström M; Tsukada H; Hartvig P; Långström B
Article: DIABETES. 2002;51(12):3376-3383

Marked heterogeneity of human skeletal muscle lipolysis at rest.

Hagström-Toft E; Qvisth V; Nennesmo I; Rydén M; Bolinder H; Enoksson S; Bolinder J; Arner P
Article: EXPERIMENTAL NEUROLOGY. 2002;177(1):314-320

CD4 and CD8 T cells, but not B cells, are critical to the control of murine experimental autoimmune neuritis.

Zhu Y; Bao L; Zhu S; Chen Z; van der Meide P; Nennesmo I; Winblad B; Ljunggren H-G; Zhu J
Article: NEUROPHARMACOLOGY. 2002;42(5):731-739

Suppression of experimental autoimmune neuritis by ABR-215062 is associated with altered Th1/Th2 balance and inhibited migration of inflammatory cells into the peripheral nerve tissue.

Zou L-P; Abbas N; Volkmann I; Nennesmo I; Levi M; Wahren B; Winblad B; Hedlund G; Zhu J
Article: ARTHRITIS & RHEUMATOLOGY. 2002;46(4):1044-1055

Interleukin-1alpha expression in capillaries and major histocompatibility complex class I expression in type II muscle fibers from polymyositis and dermatomyositis patients: important pathogenic features independent of inflammatory cell clusters in muscle tissue.

Englund P; Nennesmo I; Klareskog L; Lundberg IE
Article: BRAIN RESEARCH. 2002;931(2):135-145

Excitotoxic neurodegeneration induced by intranasal administration of kainic acid in C57BL/6 mice.

Chen Z; Ljunggren H-G; Bogdanovic N; Nennesmo I; Winblad B; Zhu J
Article: RHEUMATOLOGY. 2001;40(12):1346-1354

Increased endothelial expression of HLA-DQ and interleukin 1alpha in extra-articular rheumatoid arthritis. Results from immunohistochemical studies of skeletal muscle.

Turesson C; Englund P; Jacobsson LT; Sturfelt G; Truedsson L; Nennesmo I; Lundberg IE
Article: AMERICAN JOURNAL OF PATHOLOGY. 2001;159(4):1263-1273

Skeletal muscle fibers express major histocompatibility complex class II antigens independently of inflammatory infiltrates in inflammatory myopathies.

Englund P; Lindroos E; Nennesmo I; Klareskog L; Lundberg IE
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2001;67(3):189-193

Antibody reactivities to skeletal muscle proteins in a patient with lambda light chain secreting multiple myeloma, generalised amyloidosis and rhabdomyolysis.

Sundblad A; Porwit A; Ostad M; Nennesmo I; Holm G; Osby E; Borg K; Björkholm M
Article: JOURNAL OF RHEUMATOLOGY. 2001;28(7):1591-1599

Percutaneous conchotome muscle biopsy. A useful diagnostic and assessment tool.

Dorph C; Nennesmo I; Lundberg IE
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(4):423-426

MRI guided muscle biopsy confirmed polymyositis diagnosis in a patient with interstitial lung disease.

Lampa J; Nennesmo I; Einarsdottir H; Lundberg I
Article: ACTA NEUROLOGICA SCANDINAVICA. 2001;103(2):131-135

Report of a patient with inclusion body myositis and CD8+ chronic lymphocytic leukaemia--post-mortem analysis of muscle and brain.

Arnardottir S; Ansved T; Nennesmo I; Borg K
Article: ACTA NEUROPATHOLOGICA. 2000;100(6):709-711

Amyloid in a multiple sclerosis lesion in clearly of Alambda type.

Schröder R; Nennesmo I; Linke RP
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2000;62(5):717-721

P0 protein peptide 180-199 together with pertussis toxin induces experimental autoimmune neuritis in resistant C57BL/6 mice.

Zou LP; Ljunggren HG; Levi M; Nennesmo I; Wahren B; Mix E; Winblad B; Schalling M; Zhu J
Article: PEDIATRIC TRANSPLANTATION. 2000;4(3):211-214

Fatal deterioration of neurological disease after orthotopic liver transplantation for valproic acid-induced liver damage.

Kayihan N; Nennesmo I; Ericzon BG; Németh A
Article: CYTOKINE. 2000;12(6):808-810

High inflammation and mild demyelination in the peripheral nervous system induced by an intraneural injection of RR interleukin-4.

Deretzi G; Pelidou SH; Zou LP; Wei L; Nennesmo I; Zhu J
Article: JOURNAL OF RHEUMATOLOGY. 2000;27(4):940-948

Increased expression of interleukin 1alpha and MHC class I in muscle tissue of patients with chronic, inactive polymyositis and dermatomyositis.

Nyberg P; Wikman AL; Nennesmo I; Lundberg I
Article: ACTA NEUROLOGICA SCANDINAVICA. 2000;101(1):47-52

Polyneuropathy in late Lyme borreliosis - a clinical, neurophysiological and morphological description.

Kindstrand E; Nilsson BY; Hovmark A; Nennesmo I; Pirskanen R; Solders G; Asbrink E
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;51(1):29-35

Intranasal administration of recombinant mouse interleukin-12 increases inflammation and demyelination in chronic experimental autoimmune neuritis in Lewis rats.

Pelidou SH; Zou LP; Deretzi G; Nennesmo I; Wei L; Mix E; Van Der Meide PH; Zhu J
Article: NEUROLOGY. 1999;53(9):2190-2192

Neuroimaging study in autosomal dominant cerebellar ataxia, deafness, and narcolepsy.

Melberg A; Dahl N; Hetta J; Valind S; Nennesmo I; Lundberg PO; Raininko R
Article: AIDS. 1999;13(9):1071-1075

BK virus as the cause of meningoencephalitis, retinitis and nephritis in a patient with AIDS.

Bratt G; Hammarin AL; Grandien M; Hedquist BG; Nennesmo I; Sundelin B; Seregard S
Article: JOURNAL OF AUTOIMMUNITY. 1999;12(2):81-89

Nasal administration of recombinant rat IL-4 ameliorates ongoing experimental autoimmune neuritis and inhibits demyelination.

Deretzi G; Zou LP; Pelidou SH; Nennesmo I; Levi M; Wahren B; Mix E; Zhu J
Article: JOURNAL OF NEUROIMMUNOLOGY. 1999;94(1-2):196-203

Induction of experimental autoimmune neuritis in CD4-8-C57BL/6J mice.

Zhu J; Nennesmo I; Deng GM; Levi M; Wahren B; Diab A; Mix E; Zhou JN; Ljunggren HG
Article: OPHTHALMOLOGY. 1999;106(1):129-132

Identification of BK virus in a patient with acquired immune deficiency syndrome and bilateral atypical retinitis.

Hedquist BG; Bratt G; Hammarin AL; Grandien M; Nennesmo I; Sundelin B; Seregard S
Article: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. 1999;4(2):91-98

Lymphocytes in sural nerve biopsies from patients with plasma cell dyscrasia and polyneuropathy.

Solders G; Nennesmo I; Ernerudh J; Cruz M; Vrethem M
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 1998;77(9):939

Fatal brain edema not related to metastatic disease in a patient with choriocarcinoma.

Flam F; Nennesmo I; Sjövall K; Hannerz J; Lindqvist M
Article: AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY. 1997;18(4):384-390

Unexpected death in two young infants mimics SIDS: autopsies demonstrate tumors of medulla and heart.

Rajs J; Råsten-Almqvist P; Nennesmo I
Article: ACTA PAEDIATRICA. 1997;86(5):484-492

Treatment of adrenoleukodystrophy with bone marrow transplantation.

Malm G; Ringdén O; Anvret M; von Döbeln U; Hagenfeldt L; Isberg B; Knuutila S; Nennesmo I; Winiarski J; Marcus C
Article: JOURNAL OF PEDIATRICS. 1997;130(3):358-365

Neuropathologic findings and neurologic symptoms in twenty-three children with hemophagocytic lymphohistiocytosis.

Henter JI; Nennesmo I
Article: ACTA NEUROPATHOLOGICA. 1997;93(2):205-209

Multiple sclerosis and amyloid deposits in the white matter of the brain.

Nennesmo I; Bogdanovic N; Petrén AL; Fredrikson S
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 1997;176(1 Pt 1):49-53

Tissue distribution of transplanted fetal liver cells in the human fetal recipient.

Westgren M; Ek S; Bui T; Jansson B; Kjaeldgaard A; Markling L; Nennesmo I; Seiger A; Sarby B; Thornström S; Ringden O
Article: ACTA NEUROLOGICA SCANDINAVICA. 1996;94(4):233-241

Monozygotic twins with MELAS-like syndrome lacking ragged red fibers and lactacidaemia.

Melberg A; Akerlund P; Raininko R; Silander HC; Wibom R; Khaled A; Nennesmo I; Lundberg PO; Olsson Y
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(18):9799-9804

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation.

Lütjohann D; Breuer O; Ahlborg G; Nennesmo I; Sidén A; Diczfalusy U; Björkhem I
Article: EUROPEAN UROLOGY. 1996;29(3):355-361

Morphological and X-ray microanalytical changes in mammalian tissue after overhydration with irrigating fluids.

Hahn RG; Nennesmo I; Rajs J; Sundelin B; Wróblewski R; Zhang W
Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 1995;134(1-2):119-129

Autosomal dominant cerebellar ataxia deafness and narcolepsy.

Melberg A; Hetta J; Dahl N; Nennesmo I; Bengtsson M; Wibom R; Grant C; Gustavson KH; Lundberg PO
Article: CLINICAL AND DIAGNOSTIC VIROLOGY. 1995;4(3):223-230

No association of JC virus with Alzheimer's disease or astrocytomas.

Bogdanovic G; Hammarin AL; Grandien M; Winblad B; Bergenheim AT; Nennesmo I; Dalianis T
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Editorial comment: NEUROLOGY-GENETICS. 2021;7(6):e636

Predominant Spastic Paraparesis Associated With the D178N Mutation in PRNP.

Thams S; Paucar M; Wingård L; Thonberg H; Smith C; Nennesmo I; Svenningsson P
Editorial comment: MOLECULAR PSYCHIATRY. 2021;26(10):5471

Lack of fibrillar amyloid plaques but hypometabolism and astrogliosis in autosomal dominant variant AssPParc Alzheimer's disease

Lemoine L; Gillberg P-G; Bogdanovic N; Nennesmo I; Saint-Aubert L; Viitanen M; Graff C; Ingelsson M; Nordberg A
Other: CEREBELLUM AND ATAXIAS. 2017;4:5

An unusual cause of fatal rapid-onset ataxia plus syndrome.

Kmezic I; Weinberg J; Hauzenberger D; Hashim F; Kollia E; Klimkowska M; Nennesmo I; Paucar M
Other: CLINICAL CASE REPORTS. 2016;4(8):777-781

Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis.

Dahlin LB; Nennesmo I; Besjakov J; Ferencz I; Andersson GS; Backman C
Meeting abstract: NEUROMUSCULAR DISORDERS. 2015;25:S235

Late-onset limb-girdle muscular dystrophy caused by GMPPB-mutation

Balcin H; Palmio J; Nennesmo I; Solders G; Udd B
Letter: ACTA NEUROPATHOLOGICA. 2014;127(2):297-298

Neuropathological characterization of two siblings carrying the MAPT S305S mutation demonstrates features resembling argyrophilic grain disease.

Rönnbäck A; Nennesmo I; Tuominen H; Grueninger F; Viitanen M; Graff C
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2012;53:S72

Redox proteins in the defense against dopamine induced cell death

Arodin L; Nennesmo I; Bjornstedt M; Fernandes AP
Corrigendum: EUROPEAN JOURNAL OF HUMAN GENETICS. 2012;20(8):910

Mutations in the mitochondrial tRNA^Ser(AGY) gene are associated with deafness, retinal degeneration, myopathy and epilepsy (vol 20, pg 897, 2012)

Tuppen HAL; Naess K; Kennaway NG; Al-Dosary M; Lesko N; Yarham JW; Bruhn H; Wibom R; Nennesmo I; Weleber RG; Blakely EL; Taylor RW; McFarland R
Published paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1787(5):484-490

MtDNA mutations are a common cause of severe disease phenotypes in children with Leigh syndrome.

Naess K; Freyer C; Bruhn H; Wibom R; Malm G; Nennesmo I; von Döbeln U; Larsson N-G
Letter: ACTA NEUROPATHOLOGICA. 2005;110(3):315-316

Alzheimer pathology associated with POLG1 mutation, multiple mtDNA deletions, and APOE4/4: premature ageing or just coincidence?

Melberg A; Nennesmo I; Moslemi A-R; Kollberg G; Luoma P; Suomalainen A; Holme E; Oldfors A
Corrigendum: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2003;30(1):187

Multitracer study with positron emission tomography in Creutzfeldt-Jakob disease (vol 30, pg 187, 2003)

Engler H; Lundberg PO; Ekbom K; Nennesmo I; Nilsson A; Bergström M; Tsukada H; Hartvig P; Långström B
Letter: LANCET. 1999;354(9189):1559

Reappraisal of aluminosis and dementia.

Sjögren B; Ljunggren KG; Basun H; Frech W; Nennesmo I

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