Inga-Lena Nilsson

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Articles

Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2025;9(11):bvaf152
Familial Aggregation of Primary Hyperparathyroidism and Malignancy-Nationwide Case-Control and Cohort Study
Thorsteinsson D; Granath F; Branstrom R; Zedenius J; Nilsson I-L
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;:dgaf418
Parathyroidectomy Restores Muscle Strength and Transcriptome in Individuals With Primary Hyperparathyroidism
Bjornsdotter-Oberg S; Koman A; Skorpil M; Ryden H; Lanner JT; Krook A; Nilsson I-L; Pillon NJ; Nylen C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;110(3):693-705
BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N
Article: RARE TUMORS. 2025;17:20363613251324973
Complete remission in a rare pelvic angiosarcoma with liposomal doxorubicin: A comprehensive case report and review of literature
Graberg T; Papakonstantinou A; de Flon FH; Shabo I; Morgell A; Linder-Straglitto C; Nilsson I-L; Karlsson F; Braenstroem R
Article: WORLD JOURNAL OF SURGERY. 2024;48(2):408-415
Surgical strategy in lithium-associated hyperparathyroidism: A population-based study.
Nilsson I-L; Thorsteinsson D; Nylén C; Koman A; Granath F; Bränström R
Article: BJS OPEN. 2024;8(1):zrad154
Regional variations in the management of primary hyperparathyroidism in Sweden: population-based case-control study
Thorsteinsson D; Granath F; Branstrom R; Koman A; Zedenius J; Nilsson I-L
Article: ORAL DISEASES. 2023;29(7):2954-2961
Effects of primary hyperparathyroidism on oral health. A longitudinal register-based study
Lexomboon D; Tagt M; Nilsson I-L; Buhlin K; Habel H; Sandborgh-Englund G
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2022;187(2):257-263
Primary hyperparathyroidism, a machine learning approach to identify multiglandular disease in patients with a single adenoma found at preoperative Sestamibi-SPECT/CT
Sandqvist P; Sundin A; Nilsson I-L; Gryback P; Sanchez-Crespo A
Article: WORLD JOURNAL OF SURGERY. 2022;46(6):1420-1430
Neuropsychiatric Comorbidity in Primary Hyperparathyroidism Before and After Parathyroidectomy: A Population Study
Koman A; Branstrom R; Pernow Y; Branstrin R; Nilsson I-L; Granath F
Article: PATHOLOGY. 2021;53(7):852-859
Institutional characterisation of water clear cell parathyroid adenoma: a rare entity often unrecognised by TC-99m-sestamibi scintigraphy
Juhlin CC; Nilsson I-L; Falhammar H; Zedenius J
Article: SCANDINAVIAN JOURNAL OF SURGERY. 2021;110(3):322-328
A Single Parathyroid Hormone Measurement Two Hours after a Thyroidectomy Reliably Predicts Permanent Hypoparathyroidism
Palmhag D; Brydolf J; Zedenius J; Branstrom R; Nilsson I-L
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2021;557:14-19
Direct interaction of the ATP-sensitive K⁺ channel by the tyrosine kinase inhibitors imatinib, sunitinib and nilotinib
Frobom R; Berglund E; Aspinwall CA; Lui W-O; Nilsson I-L; Larsson C; Branstrom R
Article: INSIGHTS INTO IMAGING. 2021;12(1):72
The preoperative localisation of small parathyroid adenomas improves when adding Tc-99m-Sestamibi SPECT to multiphase contrast-enhanced CT
Sandqvist P; Farnebo J; Nilsson I-L; Gryback P; Sundin A; Sanchez-Crespo A
Article: BJS OPEN. 2021;5(2):zraa029
Prediction of cognitive response to surgery in elderly patients with primary hyperparathyroidism
Koman A; Branstrom R; Pernow Y; Branstrom R; Nilsson I-L
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2020;69(11):2393-2401
Phase I trial evaluating safety and efficacy of intratumorally administered inflammatory allogeneic dendritic cells (ilixadencel) in advanced gastrointestinal stromal tumors
Frobom R; Berglund E; Berglund D; Nilsson I-L; Ahlen J; von Sivers K; Linder-Stragliotto C; Suenaert P; Karlsson-Parra A; Branstrom R
Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;183(3):669-675
Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study
Karlsson F; Granath F; Smedby KE; Zedenius J; Branstrom R; Nilsson I-L
Article: CLINICAL ORAL INVESTIGATIONS. 2020;24(8):2755-2761
Increased risk for tooth extraction in primary hyperparathyroidism and hypercalcemia: a population study
Koman A; Nasman P; Discacciati A; Ekbom A; Nilsson I-L; Sandborgh-Englund G
Article: ENDOCRINE PATHOLOGY. 2020;31(2):156-165
Lipoadenoma of the Parathyroid Gland: Characterization of an Institutional Series Spanning 28 Years
Juhlin CC; Falhammar H; Zedenius J; Nilsson I-L; Hoog A
Article: ENDOCRINE PATHOLOGY. 2020;31(1):77-83
Metastatic Anaplastic Thyroid Carcinoma in Complete Remission: Morphological, Molecular, and Clinical Work-Up of a Rare Case
Stenman A; Hellgren LS; Jatta K; Hysek M; Zemmler M; Altena R; Nilsson I-L; Branstrom R; Zedenius J; Juhlin CC
Article: CLINICAL NUCLEAR MEDICINE. 2019;44(12):929-935
Multiphase Iodine Contrast-Enhanced SPECT/CT Outperforms Nonenhanced SPECT/CT for Preoperative Localization of Small Parathyroid Adenomas
Sandqvist P; Nilsson I-L; Gryback P; Sanchez-Crespo A; Sundin A
Article: BJS-BRITISH JOURNAL OF SURGERY. 2019;106(13):1810-1818
Short-term medical treatment of hypercalcaemia in primary hyperparathyroidism predicts symptomatic response after parathyroidectomy
Koman A; Ohlsson S; Branstrom R; Pernow Y; Nilsson I-L
Article: ANTICANCER RESEARCH. 2019;39(7):3433-3442
Biochemical Inhibition of DOG1/TMEM16A Achieves Antitumoral Effects in Human Gastrointestinal Stromal Tumor Cells In Vitro
Frobom R; Sellberg F; Xu C; Zhao A; Larsson C; Lui W-O; Nilsson I-L; Berglund E; Branstrom R
Article: MODERN PATHOLOGY. 2019;32(8):1082-1094
Parafibromin immunostainings of parathyroid tumors in clinical routine: a near-decade experience from a tertiary center
Juhlin CC; Nilsson I-L; Lagerstedt-Robinson K; Stenman A; Branstrom R; Tham E; Hoog A
Article: ONCOGENE. 2019;38(7):965-979
GABPA inhibits invasion/metastasis in papillary thyroid carcinoma by regulating DICER1 expression
Yuan X; Mu N; Wang N; Straat K; Sofiadis A; Guo Y; Stenman A; Li K; Cheng G; Zhang L; Kong F; Ekblad L; Wennerberg J; Nilsson I-L; Juhlin CC; Larsson C; Xu D
Article: ENDOCRINE PATHOLOGY. 2018;29(4):365-368
Solid Cell Nests Within a Parathyroid GlandReport of an Exceptional Case
Juhlin CC; Nilsson I-L; Hoog A
Article: ENDOCRINE. 2018;61(2):293-302
High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma
Mu N; Juhlin CC; Tani E; Sofiadis A; Reihner E; Zedenius J; Larsson C; Nilsson I-L
Article: WORLD JOURNAL OF SURGERY. 2018;42(8):2512-2521
Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs)
Ahlen J; Karlsson F; Wejde J; Nilsson I-L; Larsson C; Branstrom R
Article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2018;470:84-95
Molecular profiles of oxyphilic and chief cell parathyroid adenoma
Lu M; Kjellin H; Fotouhi O; Lee L; Nilsson I-L; Haglund F; Hoog A; Lehtio J; Larsson C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2017;177(6):445-453
Inflammatory infiltrates in parathyroid tumors
Haglund F; Hallstrom BM; Nilsson I-L; Hoog A; Juhlin CC; Larsson C
Article: SURGERY. 2017;162(2):429-436
Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy
Nilsson I-L; Norenstedt S; Zedenius J; Pernow Y; Branstrom R
Article: CLINICAL NUCLEAR MEDICINE. 2017;42(2):e109-e114
SPECT/CT's Advantage for Preoperative Localization of Small Parathyroid Adenomas in Primary Hyperparathyroidism
Sandqvist P; Nilsson I-L; Gryback P; Sanchez-Crespo A; Sundin A
Article: ENDOCRINE PATHOLOGY. 2016;27(4):346-351
Detailed Lymph Node Sectioning of Papillary Thyroid Carcinoma Specimen Increases the Number of pN1a Patients
Haglund F; Garvin S; Ihre-Lundgren C; Nilsson I-L; Hall E; Carling T; Hoog A; Juhlin CC
Article: ENDOCRINE. 2016;53(2):505-511
Minimally invasive follicular thyroid carcinomas: prognostic factors
Stenson G; Nilsson I-L; Mu N; Larsson C; Lundgren CI; Juhlin CC; Hoog A; Zedenius J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2016;174(5):583-590
Diffuse PTH expression in parathyroid tumors argues against important functional tumor subclones
Haglund F; Juhlin CC; Kiss NB; Larsson C; Nilsson I-L; Hoog A
Article: SURGERY. 2016;159(1):211-217
FGF23, metabolic risk factors, and blood pressure in patients with primary hyperparathyroidism undergoing parathyroid adenomectomy
Nilsson I-L; Norenstedt S; Granath F; Zedenius J; Pernow Y; Larsson TE
Article: ENDOCRINE CONNECTIONS. 2015;4(1):76-85
Tumour nuclear oestrogen receptor beta 1 correlates inversely with parathyroid tumour weight
Haglund F; Rosin G; Nilsson I-L; Juhlin CC; Pernow Y; Norenstedt S; Dinets A; Larsson C; Hartman J; Hoog A
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2015;172(2):181-187
Health-related quality of life after successful surgery for primary hyperparathyroidism: no additive effect from vitamin D supplementation: results of a double-blind randomized study
Aberg V; Norenstedt S; Zedenius J; Saaf M; Nordenstrom J; Pernow Y; Nilsson I-L
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2014;29(4):960-967
Vitamin D Supplementation After Parathyroidectomy: Effect on Bone Mineral Density-A Randomized Double-Blind Study
Norenstedt S; Pernow Y; Zedenius J; Nordenstrom J; Saaf M; Granath F; Nilsson I-L
Article: ANTI-CANCER DRUGS. 2014;25(4):415-422
Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells
Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Frobom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Branstrom R
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2013;169(6):795-804
Primary hyperparathyroidism and metabolic risk factors, impact of parathyroidectomy and vitamin D supplementation, and results of a randomized double-blind study
Norenstedt S; Pernow Y; Brismar K; Saaf M; Ekip A; Granath F; Zedenius J; Nilsson I-L
Article: EPIGENETICS. 2013;8(6):646-655
Global and gene-specific promoter methylation analysis in primary hyperparathyroidism
Sulaiman L; Juhlin CC; Nilsson I-L; Fotouhi O; Larsson C; Hashemi J
Article: JOURNAL OF SURGICAL ONCOLOGY. 2012;106(8):981-986
Anaplastic carcinoma of the thyroid gland: Treatment and outcome over 13 years at one institution
Segerhammar I; Larsson C; Nilsson I-L; Backdahl M; Hoog A; Wallin G; Foukakis T; Zedenius J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2012;97(12):4631-4639
Evidence of a Functional Estrogen Receptor in Parathyroid Adenomas
Haglund F; Ma R; Huss M; Sulaiman L; Lu M; Nilsson I-L; Hoog A; Juhlin CC; Hartman J; Larsson C
Article: FAMILIAL CANCER. 2012;11(3):355-362
Molecular characterization of parathyroid tumors from two patients with hereditary colorectal cancer syndromes
Andreasson A; Sulaiman L; do Vale S; Martins JM; Ferreira F; Miltenberger-Miltenyi G; Batista L; Haglund F; Bjorck E; Nilsson I-L; Hoog A; Larsson C; Juhlin CC
Article: PLOS ONE. 2012;7(7):e39519
Arterial Structure and Function in Mild Primary Hyperparathyroidism Is Not Directly Related to Parathyroid Hormone, Calcium, or Vitamin D
Ring M; Farahnak P; Gustavsson T; Nilsson I-L; Eriksson MJ; Caidahl K
Article: ENDOCRINE-RELATED CANCER. 2012;19(3):389-407
Genetic characterization of large parathyroid adenomas
Sulaiman L; Nilsson I-L; Juhlin CC; Haglund F; Hoog A; Larsson C; Hashemi J
Article: PLOS ONE. 2012;7(5):e36448
Prolactin Receptor in Primary Hyperparathyroidism - Expression, Functionality and Clinical Correlations
Haglund F; Lu M; Vukojevic V; Nilsson I-L; Andreasson A; Dzabic M; Branstrom R; Hoog A; Juhlin CC; Larsson C
Article: WORLD JOURNAL OF SURGERY. 2011;35(12):2691-2697
Thyroid Incidentaloma Detected by Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography: Practical Management Algorithm
Nilsson I-L; Arnberg F; Zedenius J; Sundin A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2011;96(7):2112-2118
Mild Primary Hyperparathyroidism: Vitamin D Deficiency and Cardiovascular Risk Markers
Farahnak P; Laerfars G; Sten-Linder M; Nilsson I-L
Article: CLINICAL EPIDEMIOLOGY. 2011;3:103-106
Breast cancer associated with primary hyperparathyroidism: a nested case control study.
Norenstedt S; Granath F; Ekbom A; Bergh J; Lambe M; Adolfsson J; Warnberg F; Zedenius J; Nilsson I-L
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2010;163(3):461-467
Cardiac function in mild primary hyperparathyroidism and the outcome after parathyroidectomy
Farahnak P; Ring M; Caidahl K; Farnebo L-O; Eriksson MJ; Nilsson I-L
Article: ENDOCRINE PATHOLOGY. 2010;21(3):166-177
Parafibromin and APC as Screening Markers for Malignant Potential in Atypical Parathyroid Adenomas
Juhlin CC; Nilsson I-L; Johansson K; Haglund F; Villablanca A; Hoog A; Larsson C
Article: JOURNAL OF WOMENS HEALTH. 2010;19(6):1117-1121
Primary Hyperparathyroidism in Pregnancy: A Diagnostic and Therapeutic Challenge
Nilsson I-L; Adner N; Reihner E; Palme-Kilander C; Edstrom G; Degerblad M
Article: CLINICAL MEDICINE INSIGHTS: ENDOCRINOLOGY AND DIABETES. 2010;3:37-42
Parathyroid Hormone's Acute Effect on Vasodilatory Function.
Farahnak P; Lind L; Mattala K; Nilsson I-L
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2009;160(2):295-299
Postoperative mortality in parathyroid surgery in Sweden during five decades: improved outcome despite older patients
Norenstedt S; Ekbom A; Brandt L; Zedenius J; Nilsson I-L
Article: ENDOCRINE-RELATED CANCER. 2007;14(1):135-140
The association between primary hyperparathyroidism and malignancy: nationwide cohort analysis on cancer incidence after parathyroidectomy
Nilsson I-L; Zedenius J; Yin L; Ekbom A
Article: SURGERY. 2005;137(6):632-638
Maintained normalization of cardiovascular dysfunction 5 years after parathyroidectomy in primary hyperparathyroidism
Nilsson IL; Åberg J; Rastad J; Lind L
Article: SURGERY. 2004;136(5):981-987
Mortality in sporadic primary hyperparathyroidism: Nationwide cohort study of multiple parathyroid gland disease
Nilsson IL; Wadsten C; Brandt L; Rastad J; Ekbom A
Article: LAKARTIDNINGEN. 2003;100(47):3848-3854
[Management of asymptomatic primary hyperparathyroidism. New North American guidelines discussed from a Swedish perspective].
Nilsson I-L; Lundgren E; Ekbom A; Ljunghall S; Rastad J
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Editorial comment: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2024;51(8):2165-2171
How nuclear imaging changed parathyroid surgical strategies through time
Schouw HM; Noltes ME; Brouwers AH; Nilsson I-L; Zedenius J; Kruijff S
Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(2):149-164
Primary hyperparathyroidism: should surgery be performed on all patients? Current evidence and residual uncertainties
Nilsson I-L
Editorial comment: SURGERY. 2016;159(1):224-225
A pilot study investigating the effect of parathyroidectomy on arterial stiffness and coronary artery calcification in patients with primary hyperparathyroidism DISCUSSION
Nilsson I-L; Berber E; Patel S; Sharma J
Editorial comment: SURGERY. 2016;159(1):217
FGF23, metabolic risk factors, and blood pressure in patients with primary hyperparathyroidism undergoing parathyroid adenomectomy DISCUSSION
Pablo Pantoja J; Nilsson I-L; Weber CJ; Holt SA
Editorial comment: SURGERY. 2016;159(1):29-30
Breast cancer in thyroid cancer survivors: An analysis of the Surveillance, Epidemiology, and End Results-9 database DISCUSSION
Nilsson I-L; Kuo JH; Garner CN; McHenry CR; Balentine CJ; Linos DA
Letter: CLINICAL ENDOCRINOLOGY. 2010;73(4):552-553
Lack of S37A CTNNB1/β-catenin mutations in a Swedish cohort of 98 parathyroid adenomas
Haglund F; Andreasson A; Nilsson I-L; Hoog A; Larsson C; Juhlin CC
Published conference paper: SURGERY. 2003;134(6):1013-1019
Circadian cardiac autonomic nerve dysfunction in primary hyperparathyroidism improves after parathyroidectomy
Nilsson IL; Åberg J; Rastad J; Lind L
Published conference paper: JOURNAL OF BONE AND MINERAL RESEARCH. 2002;17:N68-N74
Clinical presentation of primary hyperparathyroidism in Europe - Nationwide cohort analysis on mortality from nonmalignant causes
Nilsson IL; Yin L; Lundgren E; Rastad J; Ekbom A
Published conference paper: SURGERY. 2001;130(6):986-990
Endothelial vasodilatory function and blood pressure response to local and systemic hypercalcemia
Nilsson IL; Rastad J; Johansson K; Lind L
Published conference paper: SURGERY. 2000;128(6):895-902
Left ventricular systolic and diastolic function and exercise testing in primary hyperparathyroidism - effects of parathyroidectomy
Nilsson IL; Aberg J; Rastad J; Lind L
Published conference paper: SURGERY. 1999;126(6):1049-1055
Endothelial vasodilatory dysfunction in primary hyperparathyroidism is reversed after parathyroidectomy
Nilsson IL; Åberg J; Rastad J; Lind L

Grants

Primär hyperparatyreoidism, en folksjukdom. Kliniska, fysiologiska och epidemiologiska studier för förbättrad diagnostik, behandling och uppföljning
Stockholm Region
1 January 2017 - 31 December 2018
Primary hyperparathyroidism: Clinical and experimental studies to improve diagnosis and to understand the physiologic regulation of parathyroid hormone secretion
Novo Nordisk Foundation
28 August 2014 - 28 August 2015
Primary hyperparathyroidism and vitamin D deficiency, clinical implications and effects of vitamin D supplementation. Use of calcimimetics in primary hyperparathyroidism to predict the outcome of parathyroid surgery.
Novo Nordisk Foundation
24 August 2012
Vitamin D Supplementation After Parathyroid Surgery
Novo Nordisk Foundation
26 August 2011

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2027

Degrees and Education

Docent, Karolinska Institutet, 2011

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