Ibrahim El Serafi

Publications
CV
Public outreach and news

Articles

Article: CANCER RESEARCH. 2021;81(11):3022-3035
Mesothelin-Specific CAR T Cells Target Ovarian Cancer
Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: BONE MARROW TRANSPLANTATION. 2021;56(4):807-817
Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study
El-Serafi A; He R; Zheng W; Benkossou F; Oerther S; Zhao Y; Mellgren K; Gustafsson B; Heilmann C; Kanerva J; Lotfi K; Toporski J; Sundin M; Hoglund M; Mattsson J; El-Serafi I; Hassan M
Article: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 2020;13(2):293-300
Reduced Risk of Sinusoidal Obstruction Syndrome of the Liver after Busulfan-Cyclophosphamide Conditioning Prior to Allogeneic Hematopoietic Stem Cell Transplantation
El-Serafi I; Remberger M; Ringden O; Torlen J; Sundin M; Bjorklund A; Winiarski J; Mattsson J
Article: PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY. 2019;24(5):639-648
Pre-formulation investigations for establishing a protocol for treosulfan handling and activation
El-Serafi I; Loy O; Zhao Y; Oerther S; Mattsson J
Article: SCIENTIFIC REPORTS. 2018;8(1):8293
The effect of N-acetyl-l-cysteine (NAC) on liver toxicity and clinical outcome after hematopoietic stem cell transplantation
El-Serafi I; Remberger M; El-Serafi A; Benkessou F; Zheng W; Martell E; Ljungman P; Mattsson J; Hassan M
Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2017;106(4):471-475
Toxicological effects of fludarabine and treosulfan conditioning before allogeneic stem-cell transplantation
Remberger M; Torlen J; El Serafi I; Garming-Legert K; Bjorklund A; Ljungman P; Sundin M; Hassan M; Mattsson J
Article: PLOS ONE. 2017;12(11):e0187294
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
El-Serafi I; Terelius Y; Abedi-Valugerdi M; Naughton S; Saghafian M; Moshfegh A; Mattsson J; Potacova Z; Hassan M
Article: JOURNAL OF NANOBIOTECHNOLOGY. 2016;14(1):82
Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging
Asem H; Zhao Y; Ye F; Barrefelt A; Abedi-Valugerdi M; El-Sayed R; El-Serafi I; Abu-Salah KM; Hamm J; Muhammed M; Hassan M
Article: PHARMACOGENOMICS JOURNAL. 2015;15(5):405-413
Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies
El-Serafi I; Fares M; Abedi-Valugerdi M; Afsharian P; Moshfegh A; Terelius Y; Potacova Z; Hassan M
Article: PLOS ONE. 2015;10(11):e0141979
Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation
El-Serafi I; Afsharian P; Moshfegh A; Hassan M; Terelius Y
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2014;58(8):4941-4943
Posaconazole Concentrations in Human Tissues after Allogeneic Stem Cell Transplantation
Blennow O; Eliasson E; Pettersson T; Pohanka A; Szakos A; El-Serafi I; Hassan M; Ringden O; Mattsson J
Article: BIOMATERIALS. 2014;35(12):3885-3894
Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging
Ye F; Barrefelt A; Asem H; Abedi-Valugerdi M; El-Serafi I; Saghafian M; Abu-Salah K; Alrokayan S; Muhammed M; Hassan M
Article: CLINICAL DRUG INVESTIGATION. 2014;34(1):43-52
Comparison of Algorithms for Oral Busulphan Area Under the Concentration-Time Curve Limited Sampling Estimate
Sjoo F; El-Serafi I; Enestig J; Mattsson J; Liwing J; Hassan M
Article: PLOS ONE. 2014;9(1):e86619
Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation
El-Serafi I; Abedi-Valugerdi M; Potacova Z; Afsharian P; Mattsson J; Moshfegh A; Hassan M
Article: BMC PHARMACOLOGY & TOXICOLOGY. 2013;14:50
Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor-CR8-in mice
Sallam H; El-Serafi I; Meijer L; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2013;913:98-105
Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine
El-Serafi I; Terelius Y; Twelkmeyer B; Hagbjork A-L; Hassan Z; Hassan M

All other publications

Review: DIFFERENTIATION. 2017;96:26-29
Skin regeneration in three dimensions, current status, challenges and opportunities
El-Serafi AT; El-Serafi IT; Elmasry M; Steinvall I; Sjoberg F
Corrigendum: PLOS ONE. 2017;12(12):e0190181
Correction: Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway.
PLOS ONE Staff
Doctoral thesis: 2014
Genetic and metabolic studies towards personalized conditioning regimen prior to stem cell transplantation
Serafi IE
Corrigendum: PLOS ONE. 2014;9(3):e93239
Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation (vol 9, e86619, 2014)
El-Serafi I; Abedi-Valugerdi M; Potacova Z; Afsharian P; Mattsson J

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2025-2028

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2014

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