Yizhou Hu

Yizhou Hu

Postdoctoral Researcher
Visiting address: Solnavägen 9, 6C, 17177 Stockholm
Postal address: C2 Medicinsk biokemi och biofysik, C2 Molekylär neurobiologi Ernfors, 171 77 Stockholm
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About me

  • Molecular system biology, work on molecular biochemistry and translational medicine since 2005, coding since 2008. * Ph.D., Pathology (Oncology and Molecular Cell Biology), Translational Cancer Biology Program, Faculty of Medicine, University of Helsinki, Finland * M.Sc., Genetics (Human Genetics and Bioinformatics), Faculty of Biological and Environmental Sciences, University of Helsinki, Finland * B.Sc., Biotechnology (Medical Biotechnology), Life Science College of Soochow University, Suzhou, China

Research

  • Nervous system tumor, single-cell/spatial technology, developmental neurobiology, and deep learning. *Recent Publications: * * Neogenin suppresses tumor progression and metastasis via inhibiting Merlin/YAP signaling [1], Cell Death Discov., 2023 * Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages [2], Sci Adv., 2022 * Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells [3], Cell Death Dis., 2021 *Software:* 1) SWAPLINE, Single-cell Weighted Assignment and Projection on developmental LINEages [4] 2) scCAMEL, learning-based single-cell analysis toolkits, website: https://sccamel.readthedocs.io/ [5] *Dataset visualization:* 1. Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells, Cell Death Dis., 2021 Website: https://yz-studio.shinyapps.io/shinyapph5ad/ [6] [1] https://pubmed.ncbi.nlm.nih.gov/36746934/ [2] https://pubmed.ncbi.nlm.nih.gov/35675414/ [3] https://pubmed.ncbi.nlm.nih.gov/33958582/ [4] https://github.com/ernforslab/Hu-et-al._GBMlineage2022 [5] https://sccamel.readthedocs.io [6] https://yz-studio.shinyapps.io/shinyapph5ad/

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