Hui Wang

Publications
Public outreach and news

Articles

Article: NATURE COMMUNICATIONS. 2026;17(1):5238
Aurka-Bhlhe41 axis prevents premature aging-like microglial dysfunction and promotes remyelination
Yan W; Zhao Y; Li H; Hong L; Jia Q; Zhu D; Xiang D; Du L; Hu L; Bai R; Xu M; Tang Y; Chen X; Cao Y; Jia W; Wang S; Liu Y; Ren J; Pan S; Shi Y; Gao S; Dong F; Shi J; Li J; Zheng K; Yang J; Zhao S; Wang H
Article: ISCIENCE. 2026;29(2):114718
Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination
Yan W; Xiang D; Du L; Zhu D; Jia Q; Liu Y; Wang S; Liu L; Guan H; Zhao Y; Jiang G; Gao S; Wang H
Article: CANCER RESEARCH. 2025;85(13):2514-2526
Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Article: MOLECULAR BIOTECHNOLOGY. 2025;67(3):1156-1164
An Efficient Probe-Based Quantitative PCR Assay Targeting Human-Specific DNA in ST6GALNAC3 for the Quantification of Human Cells in Preclinical Animal Models.
Ren J; Liu K; Hu L; Yang R; Liu Y; Wang S; Chen X; Zhao S; Jing L; Liu T; Hu B; Zhang X; Wang H; Li H
Article: SCIENTIFIC REPORTS. 2025;15(1):3902
Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer
Mahmud AKMF; Mansour Aly DG; Zhao Y; Benson M; Smelik M; Sysoev O; Wang H; Li X
Article: IMMUNITY. 2024;57(12):2808-2826.e8
Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism.
Zou X; Wang K; Deng Y; Guan P; Pu Q; Wang Y; Mou J; Du Y; Lou X; Wang S; Jiang N; Zhou S; Wang H; Du D; Liu X; Hu H; Zhang H
Article: NATURE COMMUNICATIONS. 2024;15(1):7914
A mouse protozoan boosts antigen-specific mucosal IgA responses in a specific lipid metabolism- and signaling-dependent manner.
Kou Y; Zhang S; Chen J; Shen Y; Zhang Z; Huang H; Ma Y; Xiang Y; Liao L; Zhou J; Cheng W; Zhou Y; Yang H; Liu Z; Wei Y; Wang H; Wang Y
Article: GENOME MEDICINE. 2024;16(1):42
scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases
Schafer S; Smelik M; Sysoev O; Zhao Y; Eklund D; Lilja S; Gustafsson M; Heyn H; Julia A; Kovacs IA; Loscalzo J; Marsal S; Zhang H; Li X; Gawel D; Wang H; Benson M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;98(4):e13309
Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b
Xu M; Ren J; Jia W; Wang S; Liu Y; Chen X; Shi J; Wang H
Article: CELL REPORTS MEDICINE. 2023;4(3):100956
Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases
Lilja S; Li X; Smelik M; Lee EJ; Loscalzo J; Marthanda PB; Hu L; Magnusson M; Sysoev O; Zhang H; Zhao Y; Sjowall C; Gawel D; Wang H; Benson M
Journal article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2023;97(1)
Sputum basophils from allergic asthmatic patients do not express IL-7Rα that is essential for TSLP signalling
Gao S; Shi Y; Bai R; Li H; Ren J; Chen X; Hu L; Shi Z; Zhao S; Wang H
Article: JOURNAL OF CLINICAL INVESTIGATION. 2022;132(18):e147566
The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity.
Chen X; Hu J; Wang Y; Lee Y; Zhao X; Lu H; Zhu G; Wang H; Jiang Y; Liu F; Chen Y; Kim B-S; Zhou Q; Liu X; Wang X; Chang SH; Dong C
Article: GENOME MEDICINE. 2022;14(1):48
A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets
Li X; Lee EJ; Lilja S; Loscalzo J; Schafer S; Smelik M; Strobl MR; Sysoev O; Wang H; Zhang H; Zhao Y; Gawel DR; Bohle B; Benson M
Article: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2022;101(2):150-158
An efficient and cost-effective method for the purification of human basophils
He C; Gao S; Zhao X; Shi Y; Tang Y; Cao Y; Bai R; Ren J; Zhao S; Shi Z; Wang H
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:946202
Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41 dTomato-Cre.
Li H; Tang Y; Ren J; Bai R; Hu L; Jia W; Cao Y; Hong L; Xu M; Gao S; Shi Y; Pan S; Wang L; Zheng K; Zhao S; Wang H
Article: IMMUNOLOGY. 2021;164(2):292-304
Induction of the apoptosis, degranulation and IL-13 production of human basophils by butyrate and propionate via suppression of histone deacetylation
Shi Y; Xu M; Pan S; Gao S; Ren J; Bai R; Li H; He C; Zhao S; Shi Z; Yu F; Xiang Z; Wang H
Article: SCIENCE ADVANCES. 2021;7(36):eabh0609
Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway
Jie Z; Ko C-J; Wang H; Xie X; Li Y; Gu M; Zhu L; Yang J-Y; Gao T; Ru W; Tang S-J; Cheng X; Sun S-C
Article: CELLULAR & MOLECULAR IMMUNOLOGY. 2021;18(9):2262-2274
TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells.
Xie X; Zhu L; Jie Z; Li Y; Gu M; Zhou X; Wang H; Chang J-H; Ko C-J; Cheng X; Sun S-C
Article: CELL REPORTS. 2021;35(9):109188
Transcription factor Ascl2 promotes germinal center B cell responses by directly regulating AID transcription
Sun L; Zhao X; Liu X; Zhong B; Tang H; Jin W; Clevers H; Wang H; Wang X; Dong C
Journal article: THERANOSTICS. 2021;11(10):4655-4671
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production.
Chen X; Wang C; Sun N; Pan S; Li R; Li X; Zhao J; Tong H; Tang Y; Han J; Qiao J; Qiu H; Wang H; Yang J; Ikezoe T
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Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S6 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S20 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S15 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Table S1 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S16 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S13 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S11 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S5 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S1 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S17 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S4 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S10 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Data S1 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S19 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Data from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S8 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S22 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S21 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Figure S3 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2025
Data S2 from Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer
Smelik M; Diaz-Roncero Gonzalez D; An X; Heer R; Henningsohn L; Li X; Wang H; Zhao Y; Benson M
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