Hong Jiao

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Articles

Article: JOURNAL OF INTERNAL MEDICINE. 2024;296(3):234-248
Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs
Paucar M; Nilsson D; Engvall M; Laffita-Mesa J; Soderhall C; Skorpil M; Halldin C; Fazio P; Lagerstedt-Robinson K; Solders G; Angeria M; Varrone A; Risling M; Jiao H; Nennesmo I; Wedell A; Svenningsson P
Journal article: ATHEROSCLEROSIS. 2022;355:139
Identifying molecular defects in Swedish patients with FH: No influence of polygenic LDL cholesterol SNP-score
Benedek P; Jiao H; Kiviluoma P; Kere J; Eriksson M; Angelin B
Article: AUTISM RESEARCH. 2022;15(3):434-446
Rare variants in the outcome of social skills group training for autism
Li D; Choque Olsson N; Becker M; Arora A; Jiao H; Norgren N; Jonsson U; Bolte S; Tammimies K
Article: JOURNAL OF INTERNAL MEDICINE. 2021;290(2):404-415
Founder effects facilitate the use of a genotyping-based approach to molecular diagnosis in Swedish patients with familial hypercholesterolaemia
Benedek P; Jiao H; Duvefelt K; Skoog T; Linde M; Kiviluoma P; Kere J; Eriksson M; Angelin B
Article: NPJ GENOMIC MEDICINE. 2020;5(1):45
The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder
Li D; Choque-Olsson N; Jiao H; Norgren N; Jonsson U; Bolte S; Tammimies K
Article: DIABETES. 2019;68(12):2235-2246
Evaluation of the Genetic Association Between Adult Obesity and Neuropsychiatric Disease
Stahel P; Nahmias A; Sud SK; Lee SJ; Pucci A; Yousseif A; Youseff A; Jackson T; Urbach DR; Okrainec A; Allard JP; Sockalingam S; Yao T; Barua M; Jiao H; Magi R; Bassett AS; Paterson AD; Dahlman I; Batterham RL; Dash S
Article: NATURE COMMUNICATIONS. 2019;10(1):1396
Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions
Olive M; Engvall M; Ravenscroft G; Cabrera-Serrano M; Jiao H; Bortolotti CA; Pignataro M; Lambrughi M; Jiang H; Forrest ARR; Benseny-Cases N; Hofbauer S; Obinger C; Battistuzzi G; Bellei M; Borsari M; Di Rocco G; Viola HM; Hoo LC; Cladera J; Lagerstedt-Robinson K; Xiang F; Wredenberg A; Miralles F; Jose Baiges J; Malfatti E; Romero NB; Streichenberger N; Via C; Claeys KG; Straathof CSM; Goris A; Freyer C; Lammens M; Bassez G; Kere J; Clemente P; Sejersen T; Udd B; Vidal N; Ferrer I; Edstrom L; Wedell A; Laing NG
Article: EBIOMEDICINE. 2018;30:248-260
Long Non-Coding RNAs Associated with Metabolic Traits in Human White Adipose Tissue
Gao H; Kerr A; Jiao H; Hon C-C; Ryden M; Dahlman I; Arner P
Article: FRONTIERS IN ENDOCRINOLOGY. 2018;9:380
Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility
Costantini A; Skarp S; Kampe A; Makitie RE; Pettersson M; Mannikko M; Jiao H; Taylan F; Lindstrand A; Makitie O
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2017;32(12):2394-2404
PLS3 Deletions Lead to Severe Spinal Osteoporosis and Disturbed Bone Matrix Mineralization
Kampe AJ; Costantini A; Levy-shraga Y; Zeitlin L; Roschger P; Taylan F; Lindstrand A; Paschalis EP; Gamsjaeger S; Raas-Rothschild A; Hoevel M; Jiao H; Klaushofer K; Grasemann C; Makitie O
Article: OSTEOPOROSIS INTERNATIONAL. 2017;28(10):3023-3032
PLS3 sequencing in childhood-onset primary osteoporosis identifies two novel disease-causing variants
Kampe AJ; Costantini A; Makitie RE; Jantti N; Valta H; Mayranpaa M; Kroger H; Pekkinen M; Taylan F; Jiao H; Makitie O
Article: SCIENTIFIC REPORTS. 2017;7:45771
Sequence analysis of pooled bacterial samples enables identification of strain variation in group A streptococcus
Weldatsadik RG; Wang J; Puhakainen K; Jiao H; Jalava J; Raisanen K; Datta N; Skoog T; Vuopio J; Jokiranta TS; Kere J
Article: PLOS ONE. 2017;12(12):e0189591
CELSR2 is a candidate susceptibility gene in idiopathic scoliosis
Einarsdottir E; Grauers A; Wang J; Jiao H; Escher SA; Danielsson A; Simony A; Andersen M; Christensen SB; Akesson K; Kou I; Khanshour AM; Ohlin A; Wise C; Ikegawa S; Kere J; Gerdhem P
Article: DIABETES. 2016;65(10):2980-2989
Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity
Jiao H; Kulyte A; Naslund E; Thorell A; Gerdhem P; Kere J; Arner P; Dahlman I
Article: SCIENTIFIC REPORTS. 2016;6:33256
Investigation of rare and low-frequency variants using high-throughput sequencing with pooled DNA samples
Wang J; Skoog T; Einarsdottir E; Kaartokallio T; Laivuori H; Grauers A; Gerdhem P; Hytonen M; Lohi H; Kere J; Jiao H
Article: SCIENTIFIC REPORTS. 2016;6:29085
Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants
Kaartokallio T; Wang J; Heinonen S; Kajantie E; Kivinen K; Pouta A; Gerdhem P; Jiao H; Kere J; Laivuori H
Article: PLOS ONE. 2016;11(7):e0160197
Identification of Novel Transcribed Regions in Zebrafish (Danio rerio) Using RNA-Sequencing
Wang J; Vesterlund L; Kere J; Jiao H
Article: JOURNAL OF NEURODEVELOPMENTAL DISORDERS. 2016;8:4
Genomic sequencing of a dyslexia susceptibility haplotype encompassing ROBO1
Massinen S; Wang J; Laivuori K; Bieder A; Paez IT; Jiao H; Kere J
Article: SPINE JOURNAL. 2015;15(10):2239-2246
Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis.
Grauers A; Wang J; Einarsdottir E; Simony A; Danielsson A; Åkesson K; Ohlin A; Halldin K; Grabowski P; Tenne M; Laivuori H; Dahlman I; Andersen M; Christensen SB; Karlsson MK; Jiao H; Kere J; Gerdhem P
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2015;23(9):1216-1222
Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity
Jiao H; Arner P; Gerdhem P; Strawbridge RJ; Naslund E; Thorell A; Hamsten A; Kere J; Dahlman I
Article: PLOS ONE. 2013;8(2):e56225
Genetic Susceptibility to Non-Necrotizing Erysipelas/Cellulitis
Hannula-Jouppi K; Massinen S; Siljander T; Makela S; Kivinen K; Leinonen R; Jiao H; Aitos P; Karppelin M; Vuopio J; Syrjanen J; Kere J
Article: PLOS ONE. 2013;8(5):e61920
Ultra-Rare Mutation in Long-Range Enhancer Predisposes to Thyroid Carcinoma with High Penetrance
He H; Li W; Wu D; Nagy R; Liyanarachchi S; Akagi K; Jendrzejewski J; Jiao H; Hoag K; Wen B; Srinivas M; Waidyaratne G; Wang R; Wojcicka A; Lattimer IR; Stachlewska E; Czetwertynska M; Dlugosinska J; Gierlikowski W; Ploski R; Krawczyk M; Jazdzewski K; Kere J; Symer DE; Jin V; Wang Q; de la Chapelle A
Article: BMC MEDICAL GENOMICS. 2011;4:51
Genome wide association study identifies KCNMA1 contributing to human obesity
Jiao H; Arner P; Hoffstedt J; Brodin D; Dubern B; Czernichow S; van't Hooft F; Axelsson T; Pedersen O; Hansen T; Sorensen TIA; Hebebrand J; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2011;96(6):E962-E966
Genetic Association and Gene Expression Analysis Identify FGFR1 as a New Susceptibility Gene for Human Obesity
Jiao H; Arner P; Dickson SL; Vidal H; Mejhert N; Henegar C; Taube M; Hansson C; Hinney A; Galan P; Simon C; Silveira A; Benrick A; Jansson J-O; Bouloumie A; Langin D; Laville M; Debard C; Axelsson T; Ryden M; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: BMC DEVELOPMENTAL BIOLOGY. 2011;11:30
The zebrafish transcriptome during early development
Vesterlund L; Jiao H; Unneberg P; Hovatta O; Kere J
Article: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2010;36(3):198-210
Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas
Qu M; Jiao H; Zhao J; Ren Z-P; Smits A; Kere J; Nister M
Article: MOLECULAR HUMAN REPRODUCTION. 2009;15(7):443-449
ROCK2 allelic variants are not associated with pre-eclampsia susceptibility in the Finnish population
Peterson H; Laivuori H; Kerkela E; Jiao H; Hiltunen L; Heino S; Tiala I; Knuutila S; Rasi V; Kere J; Kivinen K
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2009;24(6):1066-1074
Genetic Regulation of Bone Traits Is Influenced by Sex and Reciprocal Cross in F₂ Progeny From GK and F344 Rats
Lagerholm S; Li L-S; Jiao H; Park H-B; Ohlsson C; Akesson K; Luthman H
Article: CANCER RESEARCH. 2009;69(2):625-631
A Susceptibility Locus for Papillary Thyroid Carcinoma on Chromosome 8q24
He H; Nagy R; Liyanarachchi S; Jiao H; Li W; Suster S; Kere J; de la Chapelle A
Article: MOLECULAR IMMUNOLOGY. 2008;46(1):202-206
Novel and recurrent STAT3 mutations in hyper-IgE syndrome patients from different ethnic groups
Jiao H; Toth B; Erdos M; Fransson I; Rakoczi E; Balogh I; Magyarics Z; Derfalvi B; Csorba G; Szaflarska A; Megarbane A; Akatcherian C; Dbaibo G; Rajnavoelgyi E; Hammarstrom L; Kere J; Lefranc G; Marodi L
Article: INTERNATIONAL JOURNAL OF OBESITY. 2008;32(5):816-825
Association analysis of positional obesity candidate genes based on integrated data from transcriptomics and linkage analysis
Jiao H; Kaaman M; Dungner E; Kere J; Arner P; Dahlman I
Article: HORMONE RESEARCH IN PAEDIATRICS. 2008;69(1):31-36
Association of ADRB1 and UCP3 gene polymorphisms with insulin sensitivity but not obesity
Mottagui-Tabar S; Hoffstedt J; Brookes AJ; Jiao H; Arner P; Dahlman I
Article: BMC MEDICAL GENETICS. 2007;8:73
Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis - a cohort study
Nilsson M; Dahlman I; Jiao H; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2007;81(3):467-474
Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic β cells
Otonkoski T; Jiao H; Kaminen-Ahola N; Tapia-Paez I; Ullah MS; Parton LE; Schuit F; Quintens R; Sipilae I; Mayatepek E; Meissner T; Halestrap AP; Rutter GA; Kere J
Article: MOLECULAR VISION. 2007;13(124-26):1154-1160
Two Chinese families with pulverulent congenital cataracts and ΔG91 CRYBA1 mutations
Lu S; Zhao C; Jiao H; Kere J; Tang X; Zhao F; Zhang X; Zhao K; Larsson C
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2007;80(6):1115-1124
A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis
Dahlman I; Dicker A; Jiao H; Kere J; Blomqvist L; van Harmelen V; Hoffstedt J; Borch-Johnsen K; Jorgensen T; Hansen T; Pedersen O; Laakso M; Arner P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2007;85(6):589-601
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes
Tiala I; Suomela S; Huuhtanen J; Wakkinen J; Hoelttae-Vuori M; Kainu K; Ranta S; Turpeinen U; Haemaelaeinen E; Jiao H; Karvonen S-L; Ikonen E; Kere J; Saarialho-Kere U; Elomaa O
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(12):881-889
Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity
Dahlman I; Nilsson M; Jiao H; Hoffstedt J; Lindgren CM; Humphreys K; Kere J; Gustafsson J-A; Arner P; Dahlman-Wright K
Article: OBESITY. 2005;13(10):1645-1650
A common β₂-adrenoceptor gene haplotype protects against obesity in Swedish women
Jiao H; Dahlman I; Eriksson P; Kere J; Arner P
Article: DIABETES. 2005;54(10):3032-3034
The CIDEA gene V115F polymorphism is associated with obesity in Swedish subjects
Dahlman I; Kaaman M; Jiao H; Kere J; Laakso M; Arner P
Article: DIABETOLOGIA. 2004;47(11):1974-1979
α₂-Heremans-Schmid glycoprotein gene polymorphisms are associated with adipocyte insulin action
Dahlman I; Eriksson P; Kaaman M; Jiao H; Lindgren CM; Kere J; Arner P
Article: HUMAN MOLECULAR GENETICS. 2004;13(15):1551-1561
Transgenic mouse models support HCR as an effector gene in the PSORS1 locus
Elomaa O; Majuri I; Suomela S; Asumalahti K; Jiao H; Mirzaei Z; Rozell B; Dahlman-Wright K; Pispa J; Kere J; Saarialho-Kere U
Article: JOURNAL OF NEUROIMMUNOLOGY. 2001;119(2):166-174
Polygenic control of autoimmune peripheral nerve inflammation in rat
Dahlman I; Wallström E; Jiao H; Luthman H; Olsson T; Weissert R
Article: MAMMALIAN GENOME. 1999;10(11):1102-1105
A rat genetic linkage map including 67 new microsatellite markers
Fakhrai-Rad H; Jiao H; Li LS; Glaser A; Koike G; Jacob HJ; Luthman H; Galli J
Article: NATURE GENETICS. 1996;12(1):31-37
Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat
Galli J; Li LS; Glaser A; Ostenson CG; Jiao H; FakhraiRad H; Jacob HJ; Lander ES; Luthman H
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All other publications

Preprint: MEDRXIV. 2023
Spinocerebellar ataxia type 4 is caused by a GGC expansion in theZFHX3gene and is associated with prominent dysautonomia and motor neuron signs
Paucar M; Nilsson D; Engvall M; Laffita-Mesa J; Söderhäll C; Skorpil M; Halldin C; Fazio P; Lagerstedt-Robinson K; Solders G; Angeria M; Varrone A; Risling M; Jiao H; Nennesmo I; Wedell A; Svenningsson P
Conference publication: ATHEROSCLEROSIS. 2022;355:E221
IDENTIFYING MOLECULAR DEFECTS IN SWEDISH PATIENTS WITH FH: NO INFLUENCE OF POLYGENIC LDL CHOLESTEROL SNP-SCORE
Benedek P; Jiao H; Kiviluoma P; Kere J; Eriksson M; Angelin B
Conference publication: ATHEROSCLEROSIS. 2021;331:E218
FOUNDER EFFECTS FACILITATE GENOTYPING APPROACH TO MOLECULAR DIAGNOSIS IN FAMILIAL HYPERCHOLESTEROLAEMIA IN SWEDEN
Benedek P; Jiao H; Duvefelt K; Skoog T; Linde M; Kiviluoma P; Kere J; Eriksson M; Angelin B
Preprint: MEDRXIV. 2021
Rare variants in the outcome of social skills group training for autism
Li D; Olsson NC; Becker M; Arora A; Jiao H; Norgren N; Jonsson U; Bölte S; Tammimies K
Corrigendum: DIABETES. 2020;69(4):798
Evaluation of the Genetic Association Between Adult Obesity and Neuropsychiatric Disease (vol 68, 2235, 2019)
Stahel P; Nahmias A; Sud SK; Lee SJ; Pucci A; Yousseif A; Youseff A; Jackson T; Urbach DR; Okrainec A; Allard JP; Sockalingam S; Yao T; Barua M; Jiao H; Magi R; Bassett AS; Paterson AD; Dahlman I; Batterham RL; Dash S
Preprint: MEDRXIV. 2019
The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder
Li D; Choque-Olsson N; Jiao H; Norgren N; Jonsson U; Bölte S; Tammimies K
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2019;27:1421-1422
Genetic determinants for social skill training outcomes in autism spectrum disorder
Li D; Rabkina I; Stamouli S; Jiao H; Becker M; Jonsson U; Choque-Olsson N; Bolte S; Tammimies K
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2019;27:123-124
PLS3 deletions lead to severe spinal osteoporosis and disturbed bone matrix mineralization
Kampe AJ; Costantini A; Levy-shraga Y; Zeitlin L; Roschger P; Taylan F; Lindstrand A; Paschalis EP; Gamsjaeger S; Raas-Rothschild A; Hoevel M; Jiao H; Klaushofer K; Grasemann C; Makitie O
Letter: JOURNAL OF INTERNAL MEDICINE. 2018;283(6):604-606
Unique case of cerebrotendinous xanthomatosis revisited: All the mutations responsible for this disease are present in the CYP27A1 gene
Jiao H; Olin M; Hansson M; Eggertsen G; Eriksson M; Angelin B; Bjorkhem I
Meeting abstract: ATHEROSCLEROSIS. 2017;263:E62
THE USE OF GENOTYPING AS A FIRST STEP IN MOLECULAR DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA
Benedek P; Angelin B; Duvefelt K; Hong J; Kere J; Rudling M; Eriksson M
Conference publication: BONE ABSTRACTS. 2017
Rare copy number variants in array-based comparative genomic hybridization in early-onset skeletal fragility
Costantini A; Skarp S; Kampe A; Pettersson M; Makitie R; Mannikko M; Jiao H; Taylan F; Lindstrand A; Makitie O
Letter: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2017;173(3):806-808
CRTAP variants in early-onset osteoporosis and recurrent fractures
Costantini A; Vuorimies I; Makitie R; Mayranpaa MK; Becker J; Pekkinen M; Valta H; Netzer C; Kampe A; Taylan F; Jiao H; Makitie O
Conference publication: JOURNAL OF CLINICAL IMMUNOLOGY. 2014;34(6):715
NOVEL AND RECURRENT STAT3 MUTATIONS IN HYPER-IGE SYNDROME PATIENTS FROM DIFFERENT ETHNIC GROUPS
Toth B; Jiao H; Erdos M; Fransson I; Rakoczi E; Balogh I; Magyarics Z; Derfalvi B; Csorba G; Szaflarska A; Megarbane A; Akatcherian C; Dbaibo G; Rajnavoelgyi E; Hammarstrom L; Kere J; Lefranck G; Marodi L
Conference publication: FEBS JOURNAL. 2014;281:322
Discovery of a novel zebrafish calponin homology-domain containing transcript using systematic search of RNA sequencing data
Vesterlund L; Wang J; Kere J; Jiao H
Conference publication: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;154:66
Novel and recurrent STAT3 mutations in hyper-IgE syndrome patients 2 from different ethnic groups
Erdos ME; Jiao H; Toth B; Erdos M; Fransson I; Rakoczi E; Balogh I; Magyarics Z; Derfalvi B; Csorba G; Szaflarska A; Megarbane A; Akatcherian C; Dbaibo G; Hammarstrom L; Kere J; Lefranc G; Marodi L
Conference publication: EUROPEAN JOURNAL OF PEDIATRICS. 2008;167(3):365
Exercise-induced hyperinsulinism:: A new disorder caused by promoter-activating mutations in the SLC16A1 gene
Meissner T; Otonkoski T; Jiao H; Kaminen-Ahola N; Tapia-Paez I; Ullah MS; Parton LE; Schuit F; Quintens R; Sipilae I; Halestrap AP; Rutter GA; Kere J; Mayatepek E
Conference publication: HYPERTENSION IN PREGNANCY. 2006;25:47
Characterization of susceptibility locus for preeclampsia on chromosome 2p25.
Peterson H; Kivinen K; Laivuori H; Kerkela E; Jiao H; Makela V-V; Hiltunen L; Kaaja R; Ylikorkala O; Rasi V; Kere J
Conference publication: CLINICA CHIMICA ACTA. 2005;355:S92
Genetic characterization of familial hypercholesterolemia in Sweden
Lind S; Jiao H; Lindgren CM; Eriksson M; Eggertsen G; Kere J; Angelin B
Conference publication: REPRODUCTIVE SCIENCES. 2004;11(2):258A
Haplotype association for preeclampsia on chromosome 2p25.
Laivuori H; Kerkela E; Jiao H; Makela VV; Kaaja R; Ylikorkala O; Kere J
Conference publication: AMERICAN JOURNAL OF HUMAN GENETICS. 2003;73(5):498
Fine mapping of susceptibility loci for preeclampsia on chromosomes 2p25, 4q23 and 9p13-p21.
Kerkelä E; Laivuori H; Jiao H; Mäkelä VV; Kaaja R; Ylikorkala O; Kere J
Thesis / dissertation: 2002
Genetic dissection of multifactorial disease models in the rat
Jiao, Hong
Conference publication: DIABETOLOGIA. 1996;39:9
Total genome scan for identification of NIDDM susceptibility factors in the GK rat
Jiao H; Li LS; Glaser A; Galli J; Fakhrairad H; Koike G; Jacob HJ; Luthman H
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Grants

Finding novel causes and new cases of hereditary dyslipidemia in Sweden - clinical, genetic and experimental studies
Swedish Heart-Lung Foundation
1 January 2021 - 31 December 2023
Genetiska undersökningar för kartläggning av orsakerna till allvarlig skolios
Swedish Research Council
1 January 2018 - 31 December 2020
A systems biology approach to unravel causes of insulin resistance in white adipose tissue
Swedish Research Council
1 January 2012 - 31 December 2015

Employments

Affiliated to Research, Department of Medicine, Huddinge, Karolinska Institutet, 2024-2025

Degrees and Education

Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2002

Supervisor

Anders Kämpe, Genetic causes and underlying disease mechanisms in early-onset osteoporosis, https://openarchive.ki.se/articles/thesis/Genetic_causes_and_underlying_disease_mechanisms_in_early-onset_osteoporosis/26919550?file=48964903

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