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About me

Assistant Professor in Global Health at KI since 2014.

Register for free here in our MOOC in Global health! It is now archived, but videos and quizzes still work. The course will be launched again in 2017!


Helena Nordenstedt finished her medical degree at the Karolinska Institutet in 2007. The same year she defended her PhD thesis in surgery with Professor Jesper Lagergren as main supervisor. After medical internship (AT) she spent 6 months in 2009-2010 at Baylor College of Medicine, Houston, Texas, USA as a postdoc under the supervision of Professor Hashem El-Serag. 

In 2012, after working as a physician in a district hospital in the eastern part of the Democratic Republic of Congo for Médecins Sans Frontières, she is currently working as an Assistant Professor in Global Health. Since 2016 she is a specialist physician in internal medicine, working half time at The Department of Internal Medicine at Danderyd University Hospital.

In October-November 2014 she worked as a physician in an Ebola treatment centre in Liberia, and in August 2015 in an Ebola treatment centre in Guinea, both missions for Médecins Sans Frontières.

Research description

Research Area

After defending her thesis in 2007, "Gastroesophageal Reflux Disease: Etiological factors", Helena Nordenstedt started studying epidemiology of esophageal, stomach and liver cancer globally. 

Since 2013 her focus of research has changed to Global health, still with an epidemiological basis, working closely with Professor Anna Mia Ekström.

In 2015 received a grant from The Swedish Research Council for a project on cardiovascular diseases in aging HIV patients in Uganda. 

Teaching portfolio

Lately Helena has been working closely with Karin Båge, Hans Rosling and other collegues, on a Massive Open Online Course (MOOC) in Global health. 

Together with Anna Mia Ekström, since 2013, Helena is responsible for a 5-week elective undergraduate course in Global health, with 70-90 students each semester, who spend 2 weeks of the course in  a low-income country like Uganda, Tanzania, Vietnam and Laos.

In 2016 she was responsible for the 2-week Non-Communicable Diseases, Injuries and Disasters course, which is part of the Master of Global Health at KI.



Comparison of mHealth and Face-to-Face Interventions for Smoking Cessation Among People Living With HIV: Meta-Analysis
Uthman Oa, Nduka Cu, Abba M, Enriquez R, Nordenstedt H, Nalugoda F, et al
JMIR mHealth and uHealth 2019;7(1):e203-

Perceptions and acceptability of an experimental Ebola vaccine among health care workers, frontline staff, and the general public during the 2014-2015 Ebola outbreak in Sierra Leone
Jalloh Mf, Jalloh Mb, Albert A, Wolff B, Callis A, Ramakrishnan A, et al
Vaccine 2019;37(11):1495-1502

Risk Communication and Ebola-Specific Knowledge and Behavior during 2014-2015 Outbreak, Sierra Leone
Winters M, Jalloh Mf, Sengeh P, Jalloh Mb, Conteh L, Bunnell R, et al
Emerging infectious diseases 2018;24(2):336-344

A meta-analysis of reflux genome-wide association studies in 6750 Northern Europeans from the general population
Bonfiglio F, Hysi Pg, Ek W, Karhunen V, Rivera Nv, Männikkö M, et al
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2017;29(2):-

Mortality among PCR negative admitted Ebola suspects during the 2014/15 outbreak in Conakry, Guinea: A retrospective cohort study
Ingelbeen B, Bah Ei, Decroo T, Balde I, Nordenstedt H, Van Griensven J, et al
PloS one 2017;12(6):e0180070-

Ebola Virus in Breast Milk in an Ebola Virus-Positive Mother with Twin Babies, Guinea, 2015
Nordenstedt H, Bah Ei, De La Vega Ma, Barry M, N'faly M, Barry M, et al
Emerging infectious diseases 2016;22(4):759-60

Electrolyte and Metabolic Disturbances in Ebola Patients during a Clinical Trial, Guinea, 2015
Ebola-tx Consortium, Van Griensven J, Bah Ei, Haba N, Delamou A, Camara Bs, et al
Emerging infectious diseases 2016;22(12):-

FGM in the time of Ebola-carpe opportunitatem
Bjälkander O, Nordenstedt H, Brolin K, Ekström Am
The Lancet. Global health 2016;4(7):e447-8

FGM in the time of Ebola-carpe opportunitatem
Bjalkander O, Nordenstedt H, Brolin K, Ekstrom Am
LANCET GLOBAL HEALTH 2016;4(7):E447-E448

Gastroesophageal Reflux and Sleep Disturbances: A Bidirectional Association in a Population-Based Cohort Study, The HUNT Study
Lindam A, Ness-jensen E, Jansson C, Nordenstedt H, Åkerstedt T, Hveem K, et al
Sleep 2016;39(7):1421-7

The Impact of the West Africa Ebola Outbreak on Obstetric Health Care in Sierra Leone
Brolin Ribacke Kj, Van Duinen Aj, Nordenstedt H, Höijer J, Molnes R, Froseth Tw, et al
PloS one 2016;11(2):e0150080-

[Challenges and opportunities for the next generation in global health]
Frielingsdorf H, Bushayija E, Nordström A, Nyberg F, Rosling H, Von Schreeb J, et al
Lakartidningen 2014;111(46):2012-3

International comparisons of acute myocardial infarction
Ejerhed J, Nordenstedt H, Laska Ac
Lancet (London, England) 2014;384(9940):303-4

Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux
Mayo Clinic Esophageal Adenocarcinoma And Barrett’s Esophagus Registry Consortium, Beacon Study Investigators, Ek We, Levine Dm, D'amato M, Pedersen Nl, et al
Journal of the National Cancer Institute 2013;105(22):1711-8

Helicobacter pylori-negative gastritis: prevalence and risk factors
Nordenstedt H, Graham Dy, Kramer Jr, Rugge M, Verstovsek G, Fitzgerald S, et al
The American journal of gastroenterology 2013;108(1):65-71

A population-based study of gastroesophageal reflux disease and sleep problems in elderly twins
Lindam A, Jansson C, Nordenstedt H, Pedersen Nl, Lagergren J
PloS one 2012;7(10):e48602-

Expression of Androgen Receptors in Barrett Esophagus
Nordenstedt H, Younes M, El-serag Hb

Gallstones and cholecystectomy in relation to risk of intra- and extrahepatic cholangiocarcinoma
Nordenstedt H, Mattsson F, El-serag H, Lagergren J
BRITISH JOURNAL OF CANCER 2012;106(5):1011-5

Physical activity, obesity and gastroesophageal reflux disease in the general population
Djärv T, Wikman A, Nordenstedt H, Johar A, Lagergren J, Lagergren P
World journal of gastroenterology 2012;18(28):3710-4

The association between Barrett's esophagus and Helicobacter pylori infection: a meta-analysis
Fischbach La, Nordenstedt H, Kramer Jr, Gandhi S, Dick-onuoha S, Lewis A, et al
Helicobacter 2012;17(3):163-75

Twelve tips for conducting a postgraduate course on study design and study protocol writing for the medical profession
Ljung R, Jansson C, Nordenstedt H, Martin L, Lagergren P, Lagergren J
MEDICAL TEACHER 2012;34(1):25-9

Increased risk of hepatocellular carcinoma after cholecystectomy
Lagergren J, Mattsson F, El-serag H, Nordenstedt H

Oesophageal adenocarcinoma: The new epidemic in men?
Rutegard M, Lagergren P, Nordenstedt H, Lagergren J
MATURITAS 2011;69(3):244-8

The influence of age, sex, and race on the incidence of esophageal cancer in the United States (1992--2006)
Nordenstedt H, El-serag H

Sex-specific exposure prevalence of established risk factors for oesophageal adenocarcinoma
Rutegard M, Nordenstedt H, Lu Y, Lagergren J, Lagergren P
BRITISH JOURNAL OF CANCER 2010;103(5):735-40

The changing pattern of epidemiology in hepatocellular carcinoma
Nordenstedt H, White Dl, El-serag Hb
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2010;42 Suppl 3():S206-14

A Population-Based Study Showing an Association Between Gastroesophageal Reflux Disease and Sleep Problems
Jansson C, Nordenstedt H, Wallander Ma, Johansson S, Johnsen R, Hveem K, et al

Environmental factors in the etiology of gastroesophageal reflux disease
Nordenstedt H, Lagergren J
Expert review of gastroenterology & hepatology 2008;2(1):93-103

Postmenopausal hormone therapy as a risk factor for gastroesophageal reflux symptoms among female twins
Nordenstedt H, Zheng Zl, Cameron Aj, Ye Wm, Pedersen Nl, Lagergren J
GASTROENTEROLOGY 2008;134(4):921-8

Severe symptoms of gastro-oesophageal reflux disease are associated with cardiovascular disease and other gastrointestinal symptoms, but not diabetes: a population-based study
Jansson C, Nordenstedt H, Wallander Ma, Johansson S, Johnsen R, Hveem K, et al

Helicobacter pylori infection and gastroesophageal reflux in a population-based study (The HUNT study)
Nordenstedt H, Nilsson M, Johnsen R, Lagergren J, Hveem K
HELICOBACTER 2007;12(1):16-22

Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins
Zheng Zl, Nordenstedt H, Pedersen Nl, Lagergren J, Ye Wm
GASTROENTEROLOGY 2007;132(1):87-95

Relation between gastroesophageal reflux symptoms and socioeconomic factors: A population-based study (the HUNT study)
Jansson C, Nordenstedt H, Johansson S, Wallander Ma, Johnsen R, Hveem K, et al

Severe gastro-oesophageal reflux symptoms in relation to anxiety, depression and coping in a population-based study
Jansson C, Nordenstedt H, Wallander Ma, Johansson S, Johnsen R, Hveem K, et al

The relation between gastroesophageal reflux and respiratory symptoms in a population-based study - The Nord-Trondelag Health Survey
Nordenstedt H, Nilsson M, Johansson S, Wallander Ma, Johnsen R, Hveem K, et al
CHEST 2006;129(4):1051-6

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