Helene Engstrand Lilja

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About me

Helene Engstrand Lilja, MD, PhD, is Adjunct Professor of Paediatric Surgery
at the Department of Women’s and Children’s Health, Karolinska
Institutet.

Articles

Article: ACTA PAEDIATRICA. 2024;113(3):550-556
Swedish registry study showed that 50% of paediatric operations were performed in university hospitals and mortality was low
Pelkonen R-M; Frykholm P; Enlund G; Lilja HE
Article: BMC PEDIATRICS. 2024;24(1):6
Experiences and satisfaction of video follow up of children with paediatric gastrointestinal conditions linking tertiary centre with guardians and clinicians at the local hospital: a cross-sectional study.
Kassa A-M; Nyström N; Waldenvik K; Engstrand Lilja H
Article: NEONATOLOGY. 2024;121(3):336-341
The Incidence of Necrotizing Enterocolitis and Late-Onset Sepsis during the COVID-19 Pandemic in Sweden: A Population-Based Cohort Study
Palleri E; Svenningsson A; Markasz L; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2023;58(11):2249-2254
Paediatric Adhesive Small Bowel Obstruction is Associated with a Substantial Economic Burden and High Frequency of Postoperative Complications.
Håkanson CA; Fredriksson F; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2023;58(10):1942-1948
Bowel Control, Bladder Function, and Quality of Life in Children with Cloacal Malformations
Ortqvist L; Holmdahl G; Borg H; Bjornland K; Lilja H; Stenstrom P; Qvist N; Hagen TS; Pakarinen M; Wester T; Rintala R
Article: JOURNAL OF PEDIATRIC SURGERY. 2023;58(9):1646-1655
Prevalence of Mental Health Problems, Associated Factors, and Health-Related Quality of Life in Children with Long-Gap Esophageal Atresia in Sweden
Dellenmark-Blom M; Ax SO; Lilja HE; Reilly C; Svensson JF; Kassa A-M; Jonsson L; Abrahamsson K; Gatzinsky V; Omling E; Tollne A; Stenstrom P; Ost E
Article: ORPHANET JOURNAL OF RARE DISEASES. 2023;18(1):233
Schooling experiences in children with long-gap esophageal atresia compared with children with esophageal atresia and primary anastomosis: a Swedish study
Dellenmark-Blom M; Reilly C; Ost E; Ax SO; Svensson JF; Kassa A-M; Jonsson L; Abrahamsson K; Gatzinsky V; Tollne AM; Omling E; Stenstrom P; Lilja HE
Article: ACTA PAEDIATRICA. 2023;112(8):1683-1688
Surgical management of necrotising enterocolitis in Sweden: A national cohort study
Svenningsson A; Borg H; Hagander L; Lilja HE
Article: DISEASES OF THE ESOPHAGUS. 2023;36(7):doac097
The risk of autism spectrum disorder and intellectual disability but not attention deficit/hyperactivity disorder is increased in individuals with esophageal atresia
Kassa A-M; Hakanson CA; Lilja HE
Article: CLINICAL NUTRITION. 2023;42(7):1095-1103
A nordic multicenter study on contemporary outcomes of pediatric short bowel syndrome in 208 patients
Mutanen A; Lilja HE; Wester T; Norrby H; Borg H; Persson S; Bjornland K; Brun AC; Telborn L; Stenstrom P; Pakarinen MP
Article: EUROPEAN JOURNAL OF PEDIATRICS. 2023;182(6):2775-2784
Paneth cell proteins DEFA6 and GUCA2A as tissue markers in necrotizing enterocolitis.
Hoffsten A; Lilja HE; Mobini-Far H; Sindelar R; Markasz L
Article: PLOS ONE. 2023;18(6):e0288061
Neurodevelopmental outcomes in individuals with VACTERL association. A population-based cohort study
Kassa A-M; Lilja HE
Article: BMC MEDICINE. 2022;20(1):492
Population-based cohort study: proton pump inhibitor use during pregnancy in Sweden and the risk of maternal and neonatal adverse events
Breddels EM; Simin J; Fornes R; Engstrand HL; Engstrand L; Bruyndonckx R; Brusselaers N
Article: GUT PATHOGENS. 2022;14(1):47
Effect of proton pump inhibitors in infants with esophageal atresia on the gut microbiome: a pilot cohort
Brusselaers N; Pereira M; Alm J; Engstrand L; Engstrand Lilja H
Article: BMC PEDIATRICS. 2022;22(1):640
Vascular adhesion protein-1 expression is reduced in the intestines of infants with necrotizing enterocolitis: an observational research study
Andersson B; Markasz L; Mobini-Far H; Lilja HE
Article: ORPHANET JOURNAL OF RARE DISEASES. 2022;17(1):239
Postoperative morbidity and health-related quality of life in children with delayed reconstruction of esophageal atresia: a nationwide Swedish study
Dellenmark-Blom M; Ax SO; Ost E; Svensson JF; Kassa A-M; Jonsson L; Abrahamsson K; Gatzinsky V; Stenstrom P; Tollne A; Omling E; Lilja HE
Article: EUROPEAN JOURNAL OF PEDIATRICS. 2022;181(6):2291-2298
Outcome and management in neonates with gastroschisis in the third millennium-a single-centre observational study
Rasanen L; Lilja HE
Article: HGG ADVANCES. 2022;3(2):100093
First genome-wide association study of esophageal atresia identifies three genetic risk loci at CTNNA3, FOXF1/FOXC2/FOXL1, and HNF1B
Gehlen J; Giel A-S; Koellges R; Haas SL; Zhang R; Trcka J; Sungur AO; Renziehausen F; Bornholdt D; Jung D; Hoyer PD; Nordenskjold A; Tibboel D; Vlot J; Spaander MCW; Smigiel R; Patkowski D; Roeleveld N; van Rooij IA; de Blaauw I; Hoelscher A; Pauly M; Leutner A; Fuchs J; Niethammer J; Melissari M-T; Jenetzky E; Zwink N; Thiele H; Hilger AC; Hess T; Trautmann J; Marks M; Baumgarten M; Blaess G; Landen M; Fundin B; Bulik CM; Pennimpede T; Ludwig M; Ludwig KU; Mangold E; Heilmann-Heimbach S; Moebus S; Herrmann BG; Alsabeah K; Burgos CM; Lilja HE; Azodi S; Stenstrom P; Arnbjornsson E; Frybova B; Lebensztejn DM; Debek W; Kolodziejczyk E; Kozera K; Kierkus J; Kalicinski P; Stefanowicz M; Socha-Banasiak A; Kolejwa M; Piaseczna-Piotrowska A; Czkwianianc E; Noethen MM; Grote P; Rygl M; Reinshagen K; Spychalski N; Ludwikowski B; Hubertus J; Heydweiller A; Ure B; Muensterer OJ; Aubert O; Gosemann J-H; Lacher M; Degenhardt P; Boemers TM; Mokrowiecka A; Malecka-Panas E; Woehr M; Knapp M; Seitz G; de Klein A; Oracz G; Brosens E; Reutter H; Schumacher J
Article: PLOS ONE. 2022;17(5):e0269163
Understanding of the transition to adult healthcare services among individuals with VACTERL association in Sweden: A qualitative study
Kassa A-M; Engvall G; Blom MD; Lilja HE
Article: PLOS ONE. 2022;17(4):e0266995
Predictors of histopathological esophagitis in infants and adolescents with esophageal atresia within a national follow-up programme
Donoso F; Beckman A; Malinovschi A; Lilja HE
Article: FRONTIERS IN PEDIATRICS. 2021;9:755437
Early Postnatal Comprehensive Biomarkers Cannot Identify Extremely Preterm Infants at Risk of Developing Necrotizing Enterocolitis
Hoffsten A; Markasz L; Lilja HE; Olsson KW; Sindelar R
Article: NEONATOLOGY. 2021;118(1):73-79
The Risk of Necrotizing Enterocolitis following the Administration of Hyperosmolar Enteral Medications to Extremely Preterm Infants
Latheef F; Wahlgren H; Lilja HE; Diderholm B; Paulsson M
Article: JOURNAL OF PEDIATRIC SURGERY. 2020;55(11):2419-2424
Adhesive small bowel obstruction after appendectomy in children - Laparoscopic versus open approach
Hakanson CA; Fredriksson F; Lilja HE
Article: BJS OPEN. 2020;4(5):943-953
Total colonic aganglionosis: multicentre study of surgical treatment and patient-reported outcomes up to adulthood
Stenstrom P; Kyrklund K; Brautigam M; Lilja HE; Stensrud KJ; Granstrom AL; Qvist N; Johansson LS; Arnbjornsson E; Borg H; Wester T; Bjornland K; Pakarinen MP
Article: BMC PEDIATRICS. 2020;20(1):400
Gender and birth weight as risk factors for anastomotic stricture after esophageal atresia repair: a systematic review and meta-analysis
Teimourian A; Donoso F; Stenstrom P; Arnadottir H; Arnbjornsson E; Lilja H; Salo M
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2020;71(2):223-231
Improved Outcome of Intestinal Failure in Preterm Infants
Fredriksson F; Nystroem N; Waldenvik K; OErden H; Lindblom M; Paulsson M; Finkel Y; Lilja HE
Article: QUALITY OF LIFE RESEARCH. 2020;29(4):913-924
Children and adolescents with VACTERL association: health-related quality of life and psychological well-being in children and adolescents and their parents
Kassa A-M; Dellenmark-Blom M; Cederberg JT; Engvall G; Lilja HE
Article: ACTA PAEDIATRICA. 2020;109(4):783-789
Attention difficulties and physical dysfunction common in children with complex congenital malformations: a study of preschool children withVACTERLassociation
Kassa A-M; Dahl M; Strinnholm M; Lilja HE
Article: PLOS ONE. 2020;15(10):e0240891
Attention deficit hyperactivity disorder and educational level in adolescent and adult individuals after anesthesia and abdominal surgery during infancy
Arana Hakanson C; Fredriksson F; Engstrand Lilja H
Article: PEDIATRIC PULMONOLOGY. 2020;55(1):206-213
Pulmonary function in children and adolescents after esophageal atresia repair
Donoso F; Hedenstrom H; Malinovschi A; Lilja HE
Article: ACTA PAEDIATRICA. 2019;108(9):1603-1608
Survival rates for surgically treated necrotising enterocolitis have improved over the last four decades
Fredriksson F; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2019;54(8):1638-1643
Functional outcome and health-related quality of life in patients with sacrococcygeal teratoma - a Swedish multicenter study
Hambraeus M; Al-Mashhadi A; Wester T; Svensson P-J; Stenstrom P; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2019;54(3):423-428
Surgical repair of long-gap esophageal atresia: A retrospective study comparing the management of long-gap esophageal atresia in the Nordic countries
Stadil T; Koivusalo A; Pakarinen M; Mikkelsen A; Emblem R; Svensson JF; Ehren H; Jonsson L; Backstrand J; Lilja HE; Donoso F; Thorup JM; Saeter T; Rasmussen L; Pedersen RN; Stenstrom P; Arnbjornsson E; Oskarsson K; Qvist N
Article: PLOS ONE. 2019;14(4):e0215751
From crisis to self-confidence and adaptation; Experiences of being a parent of a child with VACTERL association - A complex congenital malformation
Kassa A-M; Lilja HE; Engvall G
Article: GASTROENTEROLOGY RESEARCH AND PRACTICE. 2018;2018:7345426-7
Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis
Markasz L; Wanders A; Szekely L; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2017;52(11):1853-1858
Sutures impregnated with carbazate-activated polyvinyl alcohol reduce intraperitoneal adhesions
Fredriksson F; Sellberg F; Bowden T; Engstrand T; Berglund D; Lilja HE
Article: ACTA PAEDIATRICA. 2017;106(10):1694-1701
Young children with severe congenital malformations (VACTERL) expressed mixed feelings about their condition and worries about needles and anaesthesia
Kassa A-M; Engvall G; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2017;52(8):1302-1307
Patient-reported Swedish nationwide outcomes of children and adolescents with total colonic aganglionosis
Stenstrom P; Brautigam M; Borg H; Graneli C; Lilja HE; Wester T
Article: PEDIATRIC SURGERY INTERNATIONAL. 2017;33(3):317-323
Risk factors for postoperative mortality in congenital diaphragmatic hernia: a single-centre observational study
Kadir D; Lilja HE
Article: SURGERY. 2017;161(3):818-822
Absent ileocecal valve predicts the need for repeated step in children
Wester T; Lilja HE; Stenstrom P; Pakarinen M
Article: EUROPEAN JOURNAL OF PEDIATRIC SURGERY. 2017;27(1):50-55
Risk Factors for Anastomotic Strictures after Esophageal Atresia Repair: Prophylactic Proton Pump Inhibitors Do Not Reduce the Incidence of Strictures
Donoso F; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2016;51(9):1421-1425
Outcome and management in infants with esophageal atresia - A single centre observational study
Donoso F; Kassa A-M; Gustafson E; Meurling S; Lilja HE
Article: BRITISH JOURNAL OF SURGERY. 2016;103(3):284-289
Adhesive small bowel obstruction after laparotomy during infancy
Fredriksson F; Christofferson RH; Lilja HE
Article: PEDIATRIC SURGERY INTERNATIONAL. 2015;31(11):1067-1072
Outcome of laparoscopic versus open gastrostomy in children
Angsten G; Danielson J; Kassa A-M; Lilja HE
Article: MICROBIOME. 2015;3:18
Intestinal dysbiosis in children with short bowel syndrome is associated with impaired outcome
Lilja HE; Wefer H; Nystrom N; Finkel Y; Engstrand L
Article: JOURNAL OF PEDIATRIC SURGERY. 2014;49(10):1480-1484
Locally increased concentrations of inflammatory cytokines in an experimental intraabdominal adhesion model
Fredriksson F; Christofferson RH; Carlsson PO; Lilja HE
Article: BRITISH JOURNAL OF SURGERY. 2014;101(10):1329-1333
Serial transverse enteroplasty to facilitate enteral autonomy in selected children with short bowel syndrome
Wester T; Borg H; Naji H; Stenstrom P; Westbacke G; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2013;48(11):2308-2312
Genes regulating tight junctions and cell adhesion are altered in early experimental necrotizing enterocolitis
Hogberg N; Stenback A; Carlsson P-O; Wanders A; Lilja HE
Article: ACTA PAEDIATRICA. 2013;102(2):129-136
Intestinal microbial profiles in extremely preterm infants with and without necrotizing enterocolitis
Normann E; Fahlen A; Engstrand L; Lilja HE
Article: JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. 2012;36(5):587-595
Improved Outcome in Neonatal Short Bowel Syndrome Using Parenteral Fish Oil in Combination With ω-6/9 Lipid Emulsions
Angsten G; Finkel Y; Lucas S; Kassa A-M; Paulsson M; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2012;47(9):1646-1651
Intraluminal intestinal microdialysis detects markers of hypoxia and cell damage in experimental necrotizing enterocolitis
Hogberg N; Carlsson P-O; Hillered L; Stenback A; Lilja HE
Article: LAKARTIDNINGEN. 2011;108(46):2380-2381
[Does the doctor know what a child's bottom looks like? Late detection of anorectal abnormalities in children].
Naji H; Zetterlind L; Lilja HE; Gustafson E; Lindblad K; Christofferson R
Article: JOURNAL OF PEDIATRIC SURGERY. 2011;46(11):2108-2114
Predictors of postnatal outcome in neonates with gastroschisis
Kassa A-M; Lilja HE
Article: JOURNAL OF PEDIATRIC SURGERY. 2011;46(7):1361-1367
Prevention and reversal of intestinal failure-associated liver disease in premature infants with short bowel syndrome using intravenous fish oil in combination with omega-6/9 lipid emulsions
Lilja HE; Finkel Y; Paulsson M; Lucas S
Article: LAKARTIDNINGEN. 2008;105(24-25):1849-1851
[Serial transverse enteroplasty (STEP). A new surgical technique for treatment of short bowel syndrome].
Lilja HE; Finkel Y; Wester T
Article: PEDIATRIC SURGERY INTERNATIONAL. 2008;24(5):531-536
Outcome in neonates with esophageal atresia treated over the last 20 years
Lilja HE; Wester T
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000;273(1):129-135
Inhibition of signal transducer and activator transcription factor 3 in rats with acute hepatic failure
Kamohara Y; Sugiyama N; Mizuguchi T; Inderbitzin D; Lilja H; Middleton Y; Neuman T; Demetriou AA; Rozga J
Article: JOURNAL OF SURGICAL RESEARCH. 1999;85(2):243-250
Bioartificial liver treatment in rats with fulminant hepatic failure: effect on DNA-binding activity of liver-enriched and growth-associated transcription factors.
Suh KS; Lilja H; Kamohara Y; Eguchi S; Arkadopoulos N; Neuman T; Demetriou AA; Rozga J
Article: MOLECULAR CELL BIOLOGY RESEARCH COMMUNICATIONS. 1999;1(3):188-195
Transforming growth factor beta1 helps maintain differentiated functions in mitogen-treated primary rat hepatocyte cultures.
Lilja H; Kamohara Y; Neuman T; Demetriou AA; Rozga J
Article: HEPATOLOGY. 1998;28(5):1365-1370
Intrasplenic transplantation of allogeneic hepatocytes prolongs survival in anhepatic rats.
Arkadopoulos N; Lilja H; Suh KS; Demetriou AA; Rozga J
Article: CELL TRANSPLANTATION. 1998;7(4):357-363
Transplantation of hepatocytes for prevention of intracranial hypertension in pigs with ischemic liver failure
Arkadopoulos N; Chen SC; Khalili TM; Detry O; Hewitt WR; Lilja H; Kamachi H; Petrovic L; Mullon CJP; Demetriou AA; Rozga J
Article: CELL TRANSPLANTATION. 1998;7(3):257-266
Response of cultured fetal and adult rat hepatocytes to growth factors and cyclosporine.
Lilja H; Blanc P; Demetriou AA; Rozga J
Article: TRANSPLANTATION. 1997;64(9):1240-1248
Fetal rat hepatocytes: isolation, characterization, and transplantation in the Nagase analbuminemic rats.
Lilja H; Arkadopoulos N; Blanc P; Eguchi S; Middleton Y; Meurling S; Demetriou AA; Rozga J
Article: JOURNAL OF SURGICAL RESEARCH. 1997;72(2):112-122
Loss and recovery of liver regeneration in rats with fulminant hepatic failure.
Eguchi S; Lilja H; Hewitt WR; Middleton Y; Demetriou AA; Rozga J
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All other publications

Review: JOURNAL OF PEDIATRIC SURGERY. 2019;54(11):2242-2249
Surgical treatment and major complications Within the first year of life in newborns with long-gap esophageal atresia gross type A and B - a systematic review
Stadil T; Koivusalo A; Svensson JF; Jonsson L; Lilja HE; Thorup JM; Saeter T; Stenstrom P; Qvist N
Review: MICROBIOME. 2017;5(1):31
Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis
Pammi M; Cope J; Tarr PI; Warner BB; Morrow AL; Mai V; Gregory KE; Kroll JS; McMurtry V; Ferris MJ; Engstrand L; Lilja HE; Hollister EB; Versalovic J; Neu J
Letter: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 1998;78(3):306-307
Lethal autosomal recessive syndrome with intrauterine growth retardation, intra- and extrahepatic biliary atresia, and esophageal and duodenal atresia
Annerén G; Meurling S; Lilja H; Wallander J; von Döbeln U

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