Helen Kaipe

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Articles

Article: CANCER RESEARCH COMMUNICATIONS. 2024;4(2):460-474

Exhausted Tumor-infiltrating CD39⁺CD103⁺ CD8⁺ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernandez-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Lohr MJ; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1129261

Labour promotes systemic mobilisation of monocytes, T cell activation and local secretion of chemotactic factors in the intervillous space of the placenta

Vikberg S; Lindau R; Solders M; Raffetseder J; Budhwar S; Ernerudh J; Tiblad E; Kaipe H
Article: CANCERS. 2022;14(15):3826

Chemokine Receptor Expression on T Cells Is Modulated by CAFs and Chemokines Affect the Spatial Distribution of T Cells in Pancreatic Tumors

Gorchs L; Oosthoek M; Yucel-Lindberg T; Moro CF; Kaipe H
Article: MOLECULAR IMAGING AND BIOLOGY. 2021;23(6):952-962

Optimisation of the Synthesis and Cell Labelling Conditions for [⁸⁹Zr]Zr-oxine and [⁸⁹Zr]Zr-DFO-NCS: a Direct In Vitro Comparison in Cell Types with Distinct Therapeutic Applications

Friberger I; Jussing E; Han J; Goos JACM; Siikanen J; Kaipe H; Lambert M; Harris RA; Samen E; Carlsten M; Holmin S; Tran TA
Article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2021;146:103330

Decidual stromal cells support tolerance at the human foetal-maternal interface by inducing regulatory M2 macrophages and regulatory T-cells

Lindau R; Vondra S; Spreckels J; Solders M; Svensson-Arvelund J; Berg G; Pollheimer J; Kaipe H; Jenmalm MC; Ernerudh J
Article: SCIENTIFIC REPORTS. 2020;10(1):17444

The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity

Gorchs L; Ahmed S; Mayer C; Knauf A; Moro CF; Svensson M; Heuchel R; Rangelova E; Bergman P; Kaipe H
Article: STEM CELL REPORTS. 2020;14(4):648-662

Generation of Retinal Pigment Epithelial Cells Derived from Human Embryonic Stem Cells Lacking Human Leukocyte Antigen Class I and II

Petrus-Reurer S; Winblad N; Kumar P; Gorchs L; Chrobok M; KathleenWagner A; Bartuma H; Lardner E; Aronsson M; Reyes AP; Andre H; Alici E; Kaipe H; Kvanta A; Lanner F
Article: METHODS IN MOLECULAR BIOLOGY. 2020;2098:55-70

Isolation of Immune Cells from Placental Tissues and Phenotypic and Functional Analysis of MAIT Cells.

Solders M; Gorchs L; Kaipe H
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2019;82(3):e13154

Mature naive B cells are retained in the placental intervillous blood and positively associate with specific chemokines in full-term healthy pregnancy

Solders M; Lundell A-C; Gorchs L; Gidlof S; Tiblad E; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1300

Recruitment of MAIT Cells to the Intervillous Space of the Placenta by Placenta-Derived Chemokines

Solders M; Gorchs L; Tiblad E; Gidlof S; Leeansyah E; Dias J; Sandberg JK; Magalhaes I; Lundell A-C; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:847

Human Pancreatic Carcinoma-Associated Fibroblasts Promote Expression of Co-inhibitory Markers on CD4⁺ and CD8⁺ T-Cells

Gorchs L; Moro CF; Bankhead P; Kern KP; Sadeak I; Meng Q; Rangelova E; Kaipe H
Article: SCIENTIFIC REPORTS. 2017;7(1):6123

MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation

Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlof S; Tiblad E; Magalhaes I; Kaipe H
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2017;101(3):623-632

Frontline Science: Placenta-derived decidual stromal cells alter IL-2R expression and signaling in alloantigen-activated T cells

Erkers T; Solders M; Verleng L; Bergstroem C; Stikvoort A; Rane L; Nava S; Ringden O; Kaipe H
Article: SCIENTIFIC REPORTS. 2017;7:39904

IFN type I and II induce BAFF secretion from human decidual stromal cells

Lundell A-C; Nordstrom I; Andersson K; Lundqvist C; Telemo E; Nava S; Kaipe H; Rudin A
Article: STEM CELLS INTERNATIONAL. 2017;2017:8010961-15

Maternal Adaptive Immune Cells in Decidua Parietalis Display a More Activated and Coinhibitory Phenotype Compared to Decidua Basalis

Solders M; Gorchs L; Gidlof S; Tiblad E; Lundell A-C; Kaipe H
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1861

Mucosal-associated invariant T cells Display a Poor reconstitution and altered Phenotype after allogeneic hematopoietic stem cell Transplantation

Solders M; Erkers T; Gorchs L; Poiret T; Remberger M; Magalhaes I; Kaipe H
Article: CELL TRANSPLANTATION. 2016;25(2):401-410

Intra-arterial Administration of Placenta-Derived Decidual Stromal Cells to the Superior Mesenteric Artery in the Rabbit: Distribution of Cells, Feasibility, and Safety

Arnberg F; Lundberg J; Olsson A; Samen E; Jaff N; Jussing E; Dahlen U; Nava S; Axelsson R; Ringden O; Kaipe H; Holmin S
Article: CYTOTHERAPY. 2015;17(12):1732-1745

Xeno-immunosuppressive properties of human decidual stromal cells in mouse models of alloreactivity in vitro and in vivo

Sadeghi B; Heshmati Y; Khoein B; Kaipe H; Uzunel M; Walfridsson J; Ringden O
Article: STEM CELLS AND DEVELOPMENT. 2015;24(12):1471-1482

Immunogenicity of Decidual Stromal Cells in an Epidermolysis Bullosa Patient and in Allogeneic Hematopoietic Stem Cell Transplantation Patients

Kaipe H; Carlson L-M; Erkers T; Nava S; Mollden P; Gustafsson B; Qian H; Li X; Hashimoto T; Sadeghi B; Alheim M; Ringden O
Article: STEM CELLS AND DEVELOPMENT. 2015;24(2):253-263

Treatment of Severe Chronic Graft-Versus-Host Disease with Decidual Stromal Cells and Tracing with ¹¹¹Indium Radiolabeling

Erkers T; Kaipe H; Nava S; Mollden P; Gustafsson B; Axelsson R; Ringden O
Article: BONE MARROW TRANSPLANTATION. 2014;49(12):1486-1491

Superselective intra-arterial umbilical cord blood administration to BM in experimental animals

Arnberg F; Lundberg J; Kenne E; Jaff N; Mueller P; Nava S; Kaipe H; Ringden O; Holmin S
Article: STEM CELLS AND DEVELOPMENT. 2013;22(19):2596-2605

Decidual Stromal Cells Promote Regulatory T Cells and Suppress Alloreactivity in a Cell Contact-Dependent Manner

Erkers T; Nava S; Yosef J; Ringden O; Kaipe H
Article: STEM CELLS. 2013;31(3):592-601

Fetal Membrane Cells for Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease

Ringden O; Erkers T; Nava S; Uzunel M; Iwarsson E; Conrad R; Westgren M; Mattsson J; Kaipe H
Journal article: FRONTIERS IN IMMUNOLOGY. 2013;4

Decidual Stromal Cells Promote Regulatory T Cells and Suppress Alloreactivity in a Cell Contact-Dependent Manner

Tom E; Silvia N; Jena Y; Olle RN; Helen K
Article: BONE MARROW TRANSPLANTATION. 2012;47(5):706-715

Increased costs after allogeneic haematopoietic SCT are associated with major complications and re-transplantation

Svahn B-M; Remberger M; Alvin O; Karlsson H; Ringden O
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2012;18(4):557-564

Long-Term Complications, Immunologic Effects, and Role of Passage for Outcome in Mesenchymal Stromal Cell Therapy

von Bahr L; Sundberg B; Lonnies L; Sander B; Karbach H; Hagglund H; Ljungman P; Gustafsson B; Karlsson H; Le Blanc K; Ringden O
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2012;167(3):543-555

Stromal cells from term fetal membrane are highly suppressive in allogeneic settings in vitro

Karlsson H; Erkers T; Nava S; Ruhm S; Westgren M; Ringden O
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2011;87(6):503-509

Sirolimus and tacrolimus as immune prophylaxis compared to cyclosporine with or without methotrexate in patients undergoing allogeneic haematopoietic stem cell transplantation for non-malignant disorders

Ringden O; Remberger M; Dahllof G; Garming-Legert K; Karlsson H; Svenberg P; Uhlin M; Uzunel M; Mattsson J
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697

Improved Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Recent Years. A Single-Center Study

Remberger M; Ackefors M; Berglund S; Blennow O; Dahllof G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hagglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikstrom A-C; Winiarski J; Ringden O
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(4):1143-1153

N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Article: TRANSPLANTATION. 2010;90(9):1022-1029

Granulocyte Colony-Stimulating Factor Induced Acute and Chronic Graft-Versus-Host Disease

Ringden O; Hassan Z; Karlsson H; Olsson R; Omazic B; Mattsson J; Remberger M
Article: BLOOD. 2010;115(2):396-407

Functional characterization of alloreactive T cells identifies CD25 and CD71 as optimal targets for a clinically applicable allodepletion strategy

Samarasinghe S; Mancao C; Pule M; Nawroly N; Karlsson H; Brewin J; Openshaw P; Gaspar HB; Veys P; Amrolia PJ
Article: JOURNAL OF IMMUNOTHERAPY. 2010;33(1):96-105

Clinical Expansion of Cord Blood-derived T Cells for Use as Donor Lymphocyte Infusion After Cord Blood Transplantation

Okas M; Gertow J; Uzunel M; Karlsson H; Westgren M; Karre K; Ringden O; Mattsson J; Uhlin M
Article: BLOOD. 2009;114(23):4792-4803

Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease

Brewin J; Mancao C; Straathof K; Karlsson H; Samarasinghe S; Amrolia PJ; Pule M
Article: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. 2009;31(6):456-461

Improved Survival and Preserved Antiviral Responses After Combination Therapy With Daclizumab and Infliximab in Steroid-refractory Graft-Versus-Host Disease

Rao K; Rao A; Karlsson H; Jagani M; Veys P; Amrolia PJ
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2009;39(5):662-670

High circulating immunoglobulin A levels in infants are associated with intestinal toxigenic Staphylococcus aureus and a lower frequency of eczema

Lundell A-C; Hesselmar B; Nordstrom I; Saalman R; Karlsson H; Lindberg E; Aberg N; Adlerberth I; Wold AE; Rudin A
Article: TRANSPLANTATION. 2009;87(4):467-472

Increased Frequency and Responsiveness of PSA-Specific T Cells After Allogeneic Hematopoetic Stem-Cell Transplantation

Uhlin M; Okas M; Karlsson H; Gertow J; Henningsohn L; Ringden O; Karre K; Levitsky V; Mattsson J
Article: BLOOD. 2008;112(3):532-541

Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses

Karlsson H; Samarasinghe S; Ball LM; Sundberg B; Lankester AC; Dazzi F; Uzunel M; Rao K; Veys P; Le Blanc K; Ringden O; Amrolia PJ
Article: BONE MARROW TRANSPLANTATION. 2008;41(9):785-790

A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation

Barkholt L; Remberger M; Hassan Z; Fransson K; Omazic B; Svahn B-M; Karlsson H; Brune M; Hassan M; Mattsson J; Ringden O
Article: JOURNAL OF IMMUNOTHERAPY. 2007;30(5):544-556

Generation of trispecific cytotoxic T cells recognizing cytomegalovirus, adenovirus, and Epstein-Barr virus - An approach for adoptive immunotherapy of multiple pathogens

Karlsson H; Brewin J; Kinnon C; Veys P; Amrolia PJ
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2007;37(1):62-71

Increased levels of circulating soluble CD14 but not CD83 in infants are associated with early intestinal colonization with Staphylococcus aureus

Lundell A-C; Adlerberth I; Lindberg E; Karlsson H; Ekberg S; Aberg N; Saalman R; Hock B; Steinkasserer A; Hesselmar B; Wold AE; Rudin A
Article: ALLERGY. 2005;60(9):1184-1191

Cat allergen induces proinflammatory responses by human monocyte-derived macrophages but not by dendritic cells

Lundell ACA; Grindebacke H; Karlsson H; Seppälä U; Rudin A
Article: INFLAMMATION. 2004;28(3):159-168

Impact of site-specific nucleobase deletions on the arthritogenicity of DNA

Bjersing JL; Tarkowski A; Kandimalla ER; Karlsson H; Agrawal S; Collins LV
Article: INFECTION AND IMMUNITY. 2004;72(5):2671-2678

Pattern of cytokine responses to gram-positive and gram-negative commensal bacteria is profoundly changed when monocytes differentiate into dendritic cells

Karlsson H; Larsson P; Wold AE; Rudin A
Article: INFECTION AND IMMUNITY. 2002;70(12):6688-6696

Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora

Karlsson H; Hessle C; Rudin A
Article: IMMUNOLOGY. 2002;106(2):190-199

Characterization of human CD25⁺ CD4⁺ T cells in thymus, cord and adult blood

Wing K; Ekmark A; Karlsson H; Rudin A; Suri-Payer E
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All other publications

Preprint: BIORXIV. 2024

Reconstitution of the uterine immune milieu after transplantation

Strunz B; Ivarsson MA; Sun D; Ziegenhain C; Crona-Guterstam Y; Solders M; Björklund A; Marquardt N; Kaipe H; Flöter-Rådestad A; Gidlöf S; Brännström M; Björkström NK
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

TABLE 1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Table S1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S3 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S3 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S2 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 5 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 5 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Table S1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S6 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S5 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 4 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S5 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 4 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 6 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 2 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S6 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Data from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S4 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 3 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 3 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 6 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Data from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S2 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

FIGURE 2 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

Supplementary Figure S4 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024

TABLE 1 from Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer

Gorchs L; Fernández-Moro C; Asplund E; Oosthoek M; Solders M; Ghorbani P; Sparrelid E; Rangelova E; Löhr MJ; Kaipe H
Corrigendum: MOLECULAR IMAGING AND BIOLOGY. 2022;24(3):510

Optimisation of the Synthesis and Cell Labelling Conditions for [89Zr]Zr-oxine and [89Zr]Zr-DFO-NCS: a Direct In Vitro Comparison in Cell Types with Distinct Therapeutic Applications (vol 23, pg 952, 2021)

Friberger I; Jussing E; Han J; Goos JACM; Siikanen J; Kaipe H; Lambert M; Harris RA; Samen E; Carlsten M; Holmin S; Tran TA
Review: CHINESE CLINICAL ONCOLOGY. 2022;11(1):4

Immunotherapy in pancreatic cancer-an emerging role: a narrative review

Rangelova E; Kaipe H
Review: CANCERS. 2021;13(12):2995

Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines

Gorchs L; Kaipe H
Review: METHODS IN MOLECULAR BIOLOGY. 2020;2098:3-21

MAIT Cells in Health and Disease.

Magalhaes I; Solders M; Kaipe H
Review: FRONTIERS IN IMMUNOLOGY. 2020;11:1788

MAIT Cells at the Fetal-Maternal Interface During Pregnancy

Kaipe H; Raffetseder J; Ernerudh J; Solders M; Tiblad E
Conference publication: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2018;128:54

Decidual stromal cells induce homeostatic M2 macrophages and regulatory T cells

Lindau R; Vondra S; Spreckels J; Solders M; Svensson-Arvelund J; Berg G; Pollheimer J; Knoefler M; Jenmalm MC; Kaipe H; Ernerudh J
Conference publication: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2018;59(9)

In vitro and in vivo immunologic characterization of human embryonic stem cell-derived retinal pigment epithelial cells

Petrus-Reurer S; Gorchs L; Chrobok M; Wagner AK; Lardner E; Bartuma H; Aronsson M; Westman S; Alici E; Kaipe H; Lanner F; Kvanta AP
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):302

MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype

Solders M; Gorchs L; Erkers T; Lundell A-C; Nava S; Gidlof S; Tiblad E; Magalhaes I; Kaipe H
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):308-309

Phenotype and immunoregulatory functions of pancreatic carcinoma associated fibroblasts

Gorchs L; Paraschoudi G; Meng Q; Bergman P; Maeurer M; Kaipe H
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(3):S48

Placenta-Derived Decidual Stromal Cells for Treatment of Severe Acute Graft-Versus-Host Disease

Ringden O; Solders M; Baygan A; Remberger M; Erkers T; Nava S; Gustavsson B; Winiarski J; Westgren M; Sadeghi B; Mattsson J; Kaipe H
Conference publication: BONE MARROW TRANSPLANTATION. 2016;51:S319

Placenta-Derived Decidual Stromal Cells as Treatment for Haemorrhagic Cystitis in Patients Who Have Undergone Allogeneic Haematopoietic Stem Cell Transplantation (NCT02172963)

Aronsson-Kurttila W; Baygan A; Remberger M; Solders M; Erkers T; Nava S; Khoein B; Sadeghi B; Kaipe H; Ringden O
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:50

Characterization and functionality of MAIT cells at the feto-maternal interface

Solders M; Gorchs L; Erkers T; Nava S; Ringden O; Magalhaes I; Kaipe H
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:845

Placenta-derived decidual stromal cells alter IL-2R expression and signaling in alloantigen-activated T cells

Erkers T; Solders M; Verlang L; Bergstrom C; Stikvoort A; Rane L; Nava S; Ringden O; Kaipe H
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46:844-845

Ex vivo immunological analysis following decidual stromal cell therapy in patients with acute graft-versus-host disease

Erkers T; Solders M; Verleng L; Nava S; Mollden P; Mattsson J; Ringden O; Lundell A-C; Kaipe H
Conference publication: BONE MARROW TRANSPLANTATION. 2016;51:S377

Placenta-derived decidual stromal cells for treatment of severe acute graft-versus-host disease

Solders M; Baygan A; Remberger M; Erkers T; Nava S; Gustafsson B; Winiarski J; Sadeghi B; Kaipe H; Ringden O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2015;21(2):S149

Placenta-Derived Decidual Stromal Cells for Graft-Versus-Host Disease, Hemorrhaging, and Toxicity after Allogeneic Hematopoietic Stem Cell Transplantation

Ringden O; Solders M; Erkers T; Nava S; Mollden P; Khoein B; Baygan A; Aronsson-Kurttila W; Mohmand S; Remberger M; Westgren M; Mattsson J; Sadeghi B; Kaipe H
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2015;21(2):S147

Immunological Effects of Decidual Stromal Cell Treatment in Patients with Severe Chronic Graft-Versus-Host Disease

Erkers T; Kaipe H; Nava S; Mollden P; Gustafsson B; Axelsson R; Ringden O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2015;21(2):S349-S350

Decidual Stromal Cells As Treatment for Acute Graft Versus Host Disease

Solders M; Erkers T; Remberger M; Nava S; Mollden P; Mattsson J; Kaipe H; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2015;50:S315-S316

Placenta-Derived Decidual Stromal Cells for Graft-Versus-Host Disease, Hemorrhaging, and Toxicity after Allogeneic Hematopoietic Stem Cell Transplantation

Ringden O; Solders M; Erkers T; Nava S; Mollden P; Khoein B; Aronsson-Kurttila W; Mohmand S; Remberger M; Westgren M; Mattsson J; Sadeghi B; Kaipe H
Conference publication: BONE MARROW TRANSPLANTATION. 2015;50:S321-S322

Decidual stromal cells induce IL-2 insensitivity in allo-stimulated T cells in vitro

Erkers T; Bergstrom C; Nava S; Mollden P; Kaipe H
Conference publication: BONE MARROW TRANSPLANTATION. 2015;50:5572

Nifedipine and Ketoconazole is associated with a significant decrease in blood pressure and a loss of control of aGVHD and possibly GVL

Feldreich NG; Kaipe H; Ringden O; Omazic B
Conference publication: BONE MARROW TRANSPLANTATION. 2015;50:S24

Decidual stromal cells as treatment for acute graft versus host disease

Solders M; Remberger M; Erkers T; Nava S; Mollden P; Mattsson J; Kaipe H; Ringden O
Review: BONE MARROW TRANSPLANTATION. 2014;49(6):737-743

Stromal cells-are they really useful for GVHD?

Kaipe H; Erkers T; Sadeghi B; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2014;49:S128

EXPERIMENTAL AND CLINICAL STUDIES USING DECIDUAL STROMAL CELLS FROM FETAL MEMBRANE LAYERS FOR IMMUNE MODULATION AND GRAFT-VERSUS-HOST DISEASE

Sadeghi B; Erkers T; Heshmati Y; Magalhaes I; Nava S; Mollden P; Walfridsson J; Kaipe H; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2014;49:S131-S132

DECIDUAL STROMAL CELL THERAPY MAY INDUCE MULTISPECIFIC ANTI-HLA ANTIBODIES IN EPIDERMOLYSIS BULLOSA PATIENTS, BUT NOT IN ALLOGENEIC SCT PATIENTS

Kaipe H; Carlson L-M; Erkers T; Nava S; Mollden P; Alheim M; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2014;49:S126-S127

TREATMENT OF CHRONIC GRAFT-VERSUS-HOST DISEASE WITH DECIDUAL STROMAL CELLS AND TRACING WITH 111INDIUM RADIOLABELLING

Erkers T; Kaipe H; Nava S; Gustafsson B; Jansson B; Axelsson R; Ringden O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2013;19(2):S141-S142

Fetal Membrane Cells for Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease

Ringden O; Erkers T; Nava S; Uzunel M; Iwarsson E; Conrad R; Westgren M; Mattsson J; Kaipe H
Conference publication: BONE MARROW TRANSPLANTATION. 2013;48:S73

Fetal membrane cells promote regulatory T-cells and suppress alloreactivity in a cell contact-dependent manner

Erkers T; Nava S; Yosef J; Ringden O; Kaipe H
Conference publication: BONE MARROW TRANSPLANTATION. 2013;48:S175-S176

Fetal membrane cells for treatment of steroid-refractory acute graft-versus-host disease

Kaipe H; Erkers T; Nava S; Uzunel M; Iwarsson E; Conrad R; Westgren M; Mattsson J; Ringden O
Conference publication: TRANSPLANTATION AND CELLULAR THERAPY. 2012;18(2):S339

INCREASED COSTS AFTER ALLOGENEIC HAEMATOPOIETIC SCT ARE ASSOCIATED WITH MAJOR COMPLICATIONS AND RE-TRANSPLANTATION

Svahn B-M; Remberger M; Alvin O; Karlsson H; Ringden O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2012;18(2):S264

STROMAL CELLS ISOLATED FROM TERM FETAL MEMBRANE GREATLY SUPPRESS ALLOANTIGEN-STIMULATED IMMUNE CELLS IN VITRO

Erkers T; Nava S; Ruhm S; Westgren M; Ringden O; Karlsson H
Conference publication: BONE MARROW TRANSPLANTATION. 2011;46:S241-S242

Modulation of alloantigen-induced immune responses by stromal cells isolated from placental tissue

Karlsson H; Ruhm S; Nava S; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2011;46:S167-S168

Improved survival after allogeneic haematopoietic stem cell transplantation in recent years

Ringden O; Ackefors M; Berglund S; Blennow O; Dahllof G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hagglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikstrom A-C; Winiarski J; Remberger M
Review: BRITISH JOURNAL OF HAEMATOLOGY. 2009;147(5):614-633

The allogeneic graft-versus-cancer effect

Ringden O; Karlsson H; Olsson R; Omazic B; Uhlin M
Editorial comment: LANCET ONCOLOGY. 2009;10(5):440-442

Immune reconstitution after HLA mismatched haemopoietic stem-cell transplantation

Ringden O; Karlsson H; Omazic B
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):130-131

CLINICAL EXPANSION OF CORD BLOOD DERIVED T CELLS FOR USE AS DONOR LYMPHOCYTE INFUSION AFTER CORD BLOOD TRANSPLANTATION

Okas M; Gertow J; Uzunel M; Karlsson H; Uzunel M; Ringden O; Mattsson J; Ublin M
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):127

N-ACETYL-L-CYSTEINE PROMOTES T CELL MEDIATED IMMUNITY IN ALLOGENEIC SETTINGS IN VIVO AND IN VITRO

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2009;43:S51-S52

N-acetyl-L-cysteine promotes T-cell mediated immunity in allogeneic settings in vivo and in vitro

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Conference publication: BONE MARROW TRANSPLANTATION. 2009;43:S14-S15

INF-G levels before SCT are strongly correlated to acute GvHD

Uzunel M; Kearsley S; Nava S; Ruhm S; Remberger M; Karlsson H
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2008;14(2):48-49

MESENCHYMAL STEM CELLS EXERT DIFFERENTIAL EFFECTS ON ALLO-ANTIGEN- AND VIRUS-SPECIFIC T CELLS

Karlsson H; Samarasinghe S; Ball L; Sundberg B; Lankester AC; Dazzi F; Rao K; Veys P; Le Blanc K; Ringden O; Amrolia PJ
Conference publication: TRANSPLANTATION AND CELLULAR THERAPY. 2007;13(2):21

Enhanced depletion of alloreactive T cells using combined CD25/71 immunomagnetic selection

Samarasinghe S; Karlsson H; Nawroly N; Openshaw P; Veys P; Amrolia P
Conference publication: TRANSPLANTATION AND CELLULAR THERAPY. 2007;13(2):15

Preserved anti-viral responses and improved survival in steroid refractory GVHD using a combination of daclizumab and infliximab

Rao K; Rao A; Karlsson H; Veys P; Amrolia P
Conference publication: ALLERGY. 2002;57:154

Inhalant allergens induce a potent innate immune response in human cells with a cytokine pattern similar to Gram-negative bacteria

Grindebacke H; Karlsson H; Rudin A
Conference publication: ALLERGY. 2002;57:128

Cord cells are at least as potent producers of IL-12, TNF-α, IL-6 and IL-10 as adult cells in response to Gram-positive and Gram-negative bacteria

Karlsson H; Hessle C; Rudin A
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Grants

Virus infections as the cause of miscarriages and malformations: Tropism and Mechanisms

Swedish Research Council

1 January 2023 - 31 December 2026
Maternal immune cells in the intervillous space of the placenta in healthy and complicated pregnancies

Swedish Research Council

1 January 2020 - 31 December 2022
Increased understanding of how fibroblasts in pancreatic cancer affect T cells and MAIT cells - effects of reprogramming of fibroblasts to reduce tumor growth

Swedish Cancer Society

1 January 2018
Cells from placenta as treatment for severe inflammatory complications following allogeneic stem cell transplantation and other cancer treatment

Swedish Cancer Society

1 January 2017
Placenta-derived decidual stromal cells in immune regulation – implications in acute inflammatory disorders

Swedish Research Council

1 January 2016 - 31 December 2018
Cells from placenta as treatment for severe inflammatory complications following allogeneic stem cell transplantation and other cancer treatment

Swedish Cancer Society

1 January 2015
Cells from placenta as treatment for severe inflammatory complications following allogeneic stem cell transplantation and other cancer treatment

Swedish Cancer Society

1 January 2014

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