Hannah Bower

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About me

I am a research coordinator working in the Clinical Epidemiology Division at
the Department of Medicine, Solna at Karolinska Institutet. In addition to
coordinating pharmacoepidemiological projects, I also contribute to research
projects as a statistician in the Chronic Inflammatory Diseases research
group.
I defended my thesis in March 2018 at the Department of Medical Epidemiology
and Biostatistics with the title "Flexible Parametric Models for Cancer
Patient Survival: Loss in Expectation of Life and Further Developments".
*Doctoral thesis*
/Flexible parametric models for cancer patient survival : loss in expectation
of life and further developments/ [1] 2018, Department of Medical
Epidemiology and Biostatistics, Karolinska Institutet.
*University studies*
2012-2013. MSc Medical Statistics, University of Leicester, UK
2009-2012. BSc Mathematics, University of Birmingham, UK
[1] https://openarchive.ki.se/xmlui/handle/10616/46179

Articles

Article: COMMUNICATIONS IN STATISTICS PART B: SIMULATION AND COMPUTATION. 2024;53(2):993-1006
Potential bias introduced by not including multiple time-scales in survival analysis: a simulation study
Batyrbekova N; Bower H; Dickman PW; Szulkin R; Lambert PC; Andersson TM-L
Article: RMD OPEN. 2023;9(4):e003648
Are JAKis more effective among elderly patients with RA, smokers and those with higher cardiovascular risk? A comparative effectiveness study of b/tsDMARDs in Sweden
Bower H; Frisell T; di Giuseppe D; Delcoigne B; Lindstrom U; Turesson C; Chatzidionysiou K; Lindqvist E; Knight A; Forsblad-d'Elia H; Askling J
Article: BMC MEDICAL RESEARCH METHODOLOGY. 2023;23(1):291
Including uncertainty of the expected mortality rates in the prediction of loss in life expectancy
Leontyeva Y; Lambe M; Bower H; Lambert PC; Andersson TM-L
Article: RMD OPEN. 2023;9(4):e003630
Comparative cardiovascular safety with janus kinase inhibitors and biological disease-modifying antirheumatic drugs as used in clinical practice: an observational cohort study from Sweden in patients with rheumatoid arthritis
Bower H; Frisell T; di Giuseppe D; Delcoigne B; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(7):911-919
Cancer risks with JAKi and biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis or psoriatic arthritis: a national real-world cohort study
Huss V; Bower H; Hellgren K; Frisell T; Askling J; ARTIS G
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):601-610
Safety of biological and targeted synthetic disease-modifying antirheumatic drugs for rheumatoid arthritis as used in clinical practice: results from the ARTIS programme
Frisell T; Bower H; Morin M; Baecklund E; Di Giuseppe D; Delcoigne B; Feltelius N; Forsblad-d'Elia H; Lindqvist E; Lindstroem U; Askling J
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2023;52(2):111-117
Validation and characterization of venous thromboembolism diagnoses in the Swedish National Patient Register among patients with rheumatoid arthritis
Molander V; Bower H; Askling J
Article: RHEUMATOLOGY AND THERAPY. 2023;10(1):201-223
Evaluation of VTE, MACE, and Serious Infections Among Patients with RA Treated with Baricitinib Compared to TNFi: A Multi-Database Study of Patients in Routine Care Using Disease Registries and Claims Databases
Salinas CA; Louder A; Polinski J; Zhang TC; Bower H; Phillips S; Song Y; Rashidi E; Bosan R; Chang H-C; Foster N; Gershenson B; Yamanaka H; Kishimoto M; Tanaka Y; Fischer P; Zhu B; Faries D; Mai X; Doherty BT; Grelaud A; Thurin NH; Askling J; Deberdt W
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(2):189-197
Venous thromboembolism with JAK inhibitors and other immune-modulatory drugs: a Swedish comparative safety study among patients with rheumatoid arthritis
Molander V; Bower H; Frisell T; Delcoigne B; Di Giuseppe D; Askling J
Article: BMC MEDICAL RESEARCH METHODOLOGY. 2022;22(1):290
Modelling multiple time-scales with flexible parametric survival models
Batyrbekova N; Bower H; Dickman PW; Ravn Landtblom A; Hultcrantz M; Szulkin R; Lambert PC; Andersson TM-L
Article: STATA JOURNAL. 2022;22(3):679-701
Flexible parametric survival analysis with multiple timescales: Estimation and implementation using stmt
Bower H; Andersson TM-L; Crowther MJ; Lambert PC
Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2022;9(9):1449-1458
COVID-19 clinical outcomes and DMT of MS patients and population-based controls
Longinetti E; Bower H; McKay KA; Englund S; Burman J; Fink K; Fogdell-Hahn A; Gunnarsson M; Hillert J; Langer-Gould A; Lycke J; Nilsson P; Salzer J; Svenningsson A; Mellergard J; Olsson T; Piehl F; Frisell T
Article: RHEUMATOLOGY. 2022;61(9):3596-3605
Comparison of treatment retention of originator vs biosimilar products in clinical rheumatology practice in Sweden
Di Giuseppe D; Lindstrom U; Bower H; Delcoigne B; Frisell T; Chatzidionysiou K; Sjowall C; Lindqvist E; Askling J
Article: RHEUMATOLOGY. 2022;61(5):1810-1818
Short- and longer-term cancer risks with biologic and targeted synthetic disease-modifying antirheumatic drugs as used against rheumatoid arthritis in clinical practice
Huss V; Bower H; Wadstrom H; Frisell T; Askling J
Article: BMC MEDICAL RESEARCH METHODOLOGY. 2022;22(1):130
Assessing the impact of including variation in general population mortality on standard errors of relative survival and loss in life expectancy
Leontyeva Y; Bower H; Gauffin O; Lambert PC; Andersson TM-L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(3):433-439
Influenza outcomes in patients with inflammatory joint diseases and DMARDs: how do they compare to those of COVID-19?
Bower H; Frisell T; Di Giuseppe D; Delcoigne B; Askling J
Article: RMD OPEN. 2021;7(3):e001987
Effects of the COVID-19 pandemic on patients with inflammatory joint diseases in Sweden: from infection severity to impact on care provision
Bower H; Frisell T; di Giuseppe D; Delcoigne B; Ahlenius G-M; Baecklund E; Chatzidionysiou K; Feltelius N; Forsblad-d'Elia H; Kastbom A; Klareskog L; Lindqvist E; Lindstrom U; Turesson C; Sjowall C; Askling J
Article: AGE AND AGEING. 2021;50(6):2174-2182
Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?
Bai G; Szwajda A; Wang Y; Li X; Bower H; Karlsson IK; Johansson B; Aslan AKD; Pedersen NL; Hagg S; Jylhava J
Article: COMMUNICATIONS IN STATISTICS PART B: SIMULATION AND COMPUTATION. 2021;50(11):3777-3793
Capturing simple and complex time-dependent effects using flexible parametric survival models: A simulation study
Bower H; Crowther MJ; Rutherford MJ; Andersson TM-L; Clements M; Liu X-R; Dickman PW; Lambert PC
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(8):1086-1093
Impact of the COVID-19 pandemic on morbidity and mortality in patients with inflammatory joint diseases and in the general population: a nationwide Swedish cohort study
Bower H; Frisell T; Di Giuseppe D; Delcoigne B; Ahlenius G-M; Baecklund E; Chatzidionysiou K; Feltelius N; Forsblad-d'Elia H; Kastbom A; Klareskog L; Lindqvist E; Lindstrom U; Turesson C; Sjowall C; Askling J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(2):169-175
Risk of venous thromboembolism in rheumatoid arthritis, and its association with disease activity: a nationwide cohort study from Sweden
Molander V; Bower H; Frisell T; Askling J
Article: THORAX. 2020;75(12):1040-1046
Asthma and all-cause mortality in children and young adults: a population-based study
Osvald EC; Bower H; Lundholm C; Larsson H; Brew BK; Almqvist C
Article: CKJ: CLINICAL KIDNEY JOURNAL. 2020;13(5):821-827
Contemporary management of anaemia, erythropoietin resistance and cardiovascular risk in patients with advanced chronic kidney disease: a nationwide analysis
Evans M; Bower H; Cockburn E; Jacobson SH; Barany P; Carrero J-J
Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;182(3):699-707
Impact of chemotherapy, radiotherapy, and endocrine therapy on sick leave in women with early-stage breast cancer during a 5-year period: a population-based cohort study
Plym A; Johansson ALV; Bower H; Wennstig A-K; Fredriksson I; Ahlgren J; Lambe M
Article: BREAST. 2019;45:75-81
Potential gain in life years for Swedish women with breast cancer if stage and survival differences between education groups could be eliminated - Three what-if scenarios
Bower H; Andersson TM-L; Syriopoulou E; Rutherford MJ; Lambe M; Ahlgren J; Dickman PW; Lambert PC
Article: BREAST. 2019;45:48-55
Causes of sick leave, disability pension, and death following a breast cancer diagnosis in women of working age
Plym A; Johansson ALV; Bower H; Voss M; Holmberg L; Fredriksson I; Lambe M
Article: LEUKEMIA. 2018;32(10):2203-2210
Second malignancies in patients with myeloproliferative neoplasms: a population-based cohort study of 9379 patients
Landtblom AR; Bower H; Andersson TM-L; Dickman PW; Samuelsson J; Bjorkholm M; Kristinsson SY; Hultcrantz M
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2018;187(4):828-836
Adjusting Expected Mortality Rates Using Information From a Control Population: An Example Using Socioeconomic Status
Bower H; Andersson TM-L; Crowther MJ; Dickman PW; Lambe M; Lambert PC
Article: BRITISH JOURNAL OF CANCER. 2018;118(5):738-743
Loss in working years after a breast cancer diagnosis
Plym A; Bower H; Fredriksson I; Holmberg L; Lambert PC; Lambe M
Article: BRITISH JOURNAL OF CANCER. 2017;117(9):1419-1426
Estimating the impact of a cancer diagnosis on life expectancy by socio-economic group for a range of cancer types in England
Syriopoulou E; Bower H; Andersson TM-L; Lambert PC; Rutherford MJ
Article: ARCHIVES OF DISEASE IN CHILDHOOD: FETAL AND NEONATAL EDITION. 2017;102(2):F131-F135
The ORACLE Children Study: educational outcomes at 11years of age following antenatal prescription of erythromycin or co-amoxiclav
Marlow N; Bower H; Jones D; Brocklehurst P; Kenyon S; Pike K; Taylor D; Salt A
Article: STATA JOURNAL. 2016;16(4):989-1012
strcs: A command for fitting flexible parametric survival models on the log-hazard scale
Bower H; Crowther MJ; Lambert PC
Article: BLOOD CANCER JOURNAL. 2016;6(2):e390
Continued improvement in survival of acute myeloid leukemia patients: an application of the loss in expectation of life
Bower H; Andersson TM-L; Bjorkholm M; Dickman PW; Lambert PC; Derolf AR
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All other publications

Thesis / dissertation: 2018
Flexible parametric models for cancer patient survival : loss in expectation of life and further developments
Bower, Hannah
Letter: JOURNAL OF CLINICAL ONCOLOGY. 2017;35(6):696-697
Population-Level Survival for Patients With Chronic Myeloid Leukemia: Higher Survival in Sweden Than Internationally Reply
Bower H; Bjorkholm M; Dickman PW; Hoglund M; Lambert PC; Andersson TM-L
Published conference paper: JOURNAL OF CLINICAL ONCOLOGY. 2016;34(24):2851-2857
Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population
Bower H; Bjorkholm M; Dickman PW; Hoglund M; Lambert PC; Andersson TM-L
Software / code:
STRCS: Stata module to estimate flexible parametric survival models on the log hazard scale
Bower H; Crowther MJ; Lambert P

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2024-2025
Research Coordinator, Department of Medicine, Karolinska Institutet, 2019-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2018

Supervisor

Yuliya Leontyeva, Development, extensions and applications of statistical models in population-based studies to estimate loss in expectation of life (LEL) due to cancer., 2019

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