Gaetano Marrone
Researcher | Docent
E-mail: gaetano.marrone@ki.se
Visiting address: Widerströmska huset Tomtebodavägen 18 A, plan 3, 17165 Solna
Postal address: K9 Global folkhälsa, K9 GPH Stålsby Lundborg, 171 77 Stockholm
About me
- On leave of abscence from April 2021 until April 2022.
Gaetano is associate professor in Global Health, employed at the
Department of Public Health Sciences, Karolinska Institutet, Stockholm, and
at the Department of Infectious Diseases, Karolinska Hospital, Stockholm
County Council. Gaetano has a PhD in Public Health (2010) from the University
of Pavia (Italy), and a Master degree in Statistical and Economical Sciences
(Faculty of Economics, University of Bari, Italy).
His main areas of research are HIV/AIDS epidemiology and antibiotic use and
resistance. He has extensive collaborations with Public Health England,
Swedish National Board of Health and Welfare, ECDC (European Center for
Disease Control), AMREF (African Medical and Research Foundation) Kenya,
AMREF Tanziania, R.D. Gardi Medical College (Ujjain, Madhya Pradesh, India),
Tata Institute of Social Sciences (Mumbai, India), Makerere University
(Kampala, Uganda) and National Centre for AIDS and STD Control (Kathmandu,
Nepal).
Since 2009 he is the course leader for the Research Methodology course,
Master in Global Health, and since 2012 also lecturer for KI’s Master in
Public Health track Epidemiology. The topics of these courses include
epidemiology, study design, sampling methods, data management and
biostatistics. Moreover, he has organised several data management training
courses in Kenya, Uganda and Tanzania. He has published more than 50
scientific papers.
Research
- I am the Principal Investigator of a project regarding Incidence and risk
factors of cardiovascular diseases amongst people living with HIV in Sweden:
a retrospective cohort study.
I am also involved in on-going collaborative projects in India, China,
Uganda, Nepal, Ethiopia and Sweden. Being a biostatistican by training, I
focus mainly on the research methodology part (study design, sampling
methods, sample size calculation, statistical analysis, scientific writing
and manuscript revisions).
In India, I am involved in the Antibiotics prescription part of APRIAM study.
The aim is to analyze the antibiotic prescribing in two tertiary
care, private sector hospitals, one teaching and one non-teaching.
It is an ongoing study where the antibiotics prescribed to the patients
admitted in two Indian tertiary care hospitals is being followed since 2007.
In China, I am involved in two main projects:
- IMPACT: a One Health project investigating antibiotic use and resistance in
a rural area of China, and finding ways to improve the situation. It is a
joint collaboration between institutions in China and Sweden, and has
received five years of funding from the National Natural Sciences Foundation
of China and the Swedish Research Council
- Collaboration between Guangdong Provincial Hospital of Chinese Medicine and
Karolinska Institutet under the theme ’Prevention, control and treatment of
infections and other diseases’. The planned research topics are:
1) Evaluation of an exercise-based cardiac rehabilitation program for
patients with chronic heart failure in China.
2) Infection-related hospitalizations in Chinese patients with chronic
disease.
Efficacy and Safety of Sanfu Herbal Patch at Acupuncture points for
Persistent Allergic Rhinitis (SPAR): a randomized controlled clinical trial.
3) Efficacy and costs of Chinese herbal medicine for flu A H1N1.
In Uganda, I am involved in a project on Innovations in the health system and
interventions for improved treatment of infectious diseases in children in
rural Uganda. The aim is to find better diagnostics and algorithms for
increased quality of care, rational use of medicines and minimized
antimicrobial resistance.
In Nepal, I am involved in a projects studying effectiveness of HIV
preventive interventions at population-level among vulnerable young
populations (men who have sex with men, female sex workers, people who inject
drugs and migrants).
In Ethiopia, I am involved in two projects:
1) Developing & - evaluating a predictive model from routinely used
immunological, hematological, & - clinical parameters to be used as a screening
tool for Anti Retroviral Treatment (ART) failure.
2) Molecular evolution of HIV-1 subtype C and its impact in therapeutic
response.
I am also involved in a number of other projects in Sweden, about:
- Antibiotics use, knowledge and attitude
- Patients´ treatment satisfaction with health and care within the Swedish
Cohort InfCareHIV
- Incidence of HPV induced cancer in HIV infected patients in Sweden.
- Assigning probable country of HIV acquisition among adults born abroad
based on estimation CD4 cell decline and CD4 cell count at HIV
sero-conversion among HIV sero-convertors.
Since 2009 I am the course leader for the Research Methodology course, Master
in Global Health, and since 2012 also lecturer for KI’s Master in Public
Health track Epidemiology.
Teaching
- Typically, my learning activities include lectures, group work and practical
sessions.
Morning lectures are generally theoretical lectures of 3.5 hours with the use
of power point presentations and white board, with the main aim of providing
at least factual knowledge while in the afternoon students are required to
apply and interpret the concepts taught during the morning session, with
practical exercises and the use of the statistical software SPSS (3 hours).
Moreover, I use to arrange group activities dividing the students in 6 groups
of around 6-7 students each. Groups are based according to the free choice of
the students on reading published papers on qualitative, cross-sectional,
case-control, cohort, and ecological or randomized controlled trial design.
Towards the end of the course each group prepares a presentation where they
summarize the study and try to critically discuss with me the paper they have
chosen (strengths and limitations, what they would have done different if
they were the PI of the project etc). The audience participate actively as
well commenting and asking questions. This is a good way to practically show
the students how much now they are able to read, understand, interpret and
even criticize others pieces of work.
Even though the group work is not evaluated officially, it creates the basis
for me for a self-assessment of what the students have learned during the
course.
The examination consists in a written exam with 24 questions, some with
multiple choices, some open-ended questions and some questions were
calculations are needed. While preparing the official assessment, I try to
align it to the course content and the syllabus and to use the assessment to
evaluate the course content. At the end of the course students are asked to
evaluate the course and how they feel the course have been useful for them.
They are also asked what they have liked and not liked, and what their
recommendations are in order to improve the course in the future.
I dedicate around 20% of my full-time employment to teaching activities. I
have been teaching statistics the first cycle education outside KI (Bachelor
degree in Medicine and Bachelor degree in Biotechnology, Medical University
of Pavia, Italy) - I have been teaching Research methodology within
second-cycle education (Master´s) at KI (mainly Masters´programme in Global
Health and Public Health Sciences), and within second-cycle education
(Master´s) in another HEI (Course in Biostatistics, Master in Medicine,
Medical University of Pavia). Moreover, I have been involved in several
workshops and teaching exchange programs in Kenya, Tanzania, Uganda and
China. I am also involved extensively in supervision of master thesis and
evaluation of master thesis: so far, more than MSc students have completed
their thesis under my supervision and I have evaluated around 10 master
theses.
Articles
- Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2024;59(9):1111-1121
- Article: EUROSURVEILLANCE. 2023;28(48):2300642
- Article: INTERNATIONAL JOURNAL OF DRUG POLICY. 2023;119:104145
- Article: EUROSURVEILLANCE. 2023;28(19):2200575
- Article: EUROSURVEILLANCE. 2023;28(11):2200114
- Article: CLINICAL INFECTIOUS DISEASES. 2023;76(1):25-31
- Article: AIDS. 2022;36(13):1829-1834
- Article: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 2022;25(4):e25901
- Article: BMC NEPHROLOGY. 2022;23(1):93
- Article: EUROSURVEILLANCE. 2022;27(7):2200060
- Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2022;38(2):135-142
- Article: MICROBIOLOGY SPECTRUM. 2021;9(3):e0181021-e01821
- Article: GLOBAL HEART. 2021;16(1):83-13
- Article: SCIENTIFIC REPORTS. 2021;11(1):22599
- Article: JOURNAL OF CLINICAL EPIDEMIOLOGY. 2021;139:330-339
- Article: BMC PSYCHIATRY. 2021;21(1):476
- Article: EUROSURVEILLANCE. 2021;26(33):2000161
- Article: CLINICAL INFECTIOUS DISEASES. 2021;72(12):2079-2086
- Article: OPEN FORUM INFECTIOUS DISEASES. 2021;8(6):ofab131
- Article: ANTIBIOTICS-BASEL. 2021;10(4):371
- Article: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS. 2021;152(3):386-394
- Article: SEXUALLY TRANSMITTED INFECTIONS. 2021;97(2):141-146
- Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2021;8:715207
- Article: THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE. 2021;8:20499361211062107
- Article: ESC HEART FAILURE. 2020;7(6):3782-3791
- Article: HEALTH AND QUALITY OF LIFE OUTCOMES. 2020;18(1):298
- Article: BMC INFECTIOUS DISEASES. 2020;20(1):402
- Article: BMC INFECTIOUS DISEASES. 2020;20(1):340
- Article: PLOS ONE. 2020;15(12):e0242710
- Article: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS. 2019;147(3):389-396
- Article: TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE. 2019;113(11):714-721
- Article: BMC INFECTIOUS DISEASES. 2019;19(1):569
- Article: JOURNAL OF INFECTION. 2019;78(5):402-408
- Article: SCIENTIFIC REPORTS. 2019;9(1):6682
- Article: BMJ GLOBAL HEALTH. 2019;4(2):e001214
- Article: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS. 2019;144(1):37-48
- Article: EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2018;57:32-38
- Article: SCIENTIFIC REPORTS. 2018;8(1):13372
- Article: ACTA PAEDIATRICA. 2018;107(9):1548-1554
- Article: CURRENT HIV RESEARCH. 2018;16(2):113-120
- Article: SCIENTIFIC REPORTS. 2018;8(1):7556
- Article: AIDS. 2018;32(7):877-884
- Article: JOURNAL OF TRADITIONAL CHINESE MEDICINE = CHUNG I TSA CHIH YING WEN PAN / SPONSORED BY ALL-CHINA ASSOCIATION OF TRADITIONAL CHINESE MEDICINE, ACADEMY OF TRADITIONAL CHINESE MEDICINE. 2018;38(1):107-116
- Article: PLOS ONE. 2018;13(7):e0200505
- Article: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2017;124(11):1680-1687
- Article: ACTA PAEDIATRICA. 2017;106(10):1674-1683
- Article: HIV MEDICINE. 2017;18(9):677-684
- Article: SCIENTIFIC REPORTS. 2017;7(1):11530
- Article: INTERNATIONAL JOURNAL OF STD & AIDS. 2017;28(9):864-875
- Article: SUBSTANCE USE & MISUSE. 2017;52(9):1170-1180
- Article: SCIENTIFIC REPORTS. 2017;7(1):6371
- Article: BMC INFECTIOUS DISEASES. 2017;17(1):37
- Article: PLOS ONE. 2017;12(9):e0182688
- Article: PLOS ONE. 2017;12(8):e0182384
- Article: BMC INFECTIOUS DISEASES. 2016;16(1):759
- Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2016;49:100-106
- Article: HIV MEDICINE. 2016;17(6):425-435
- Article: INTERNATIONAL JOURNAL FOR EQUITY IN HEALTH. 2016;15:71
- Article: HEALTH CARE FOR WOMEN INTERNATIONAL. 2016;37(4):392-411
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2016;31(4):395-404
- Article: BMJ OPEN. 2016;6(1):e009056
- Article: PLOS ONE. 2016;11(9):e0163597
- Article: PLOS ONE. 2016;11(9):e0162503
- Article: JOURNAL OF AGROMEDICINE. 2016;21(4):335-344
- Article: PLOS ONE. 2016;11(7):e0159359
- Article: PLOS ONE. 2016;11(6):e0156916
- Article: PLOS ONE. 2016;11(4):e0152160
- Article: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 2015;70(2):e36-e43
- Article: BMC RESEARCH NOTES. 2015;8:495
- Article: GLOBAL HEALTH ACTION. 2015;8:23969
- Article: ORAL HEALTH & PREVENTIVE DENTISTRY. 2015;13(1):75-83
- Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2014;11(9):8996-9007
- Article: AFRICAN JOURNAL OF REPRODUCTIVE HEALTH. 2014;18(1):102-109
- Article: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 2014;17(1):18841
- Article: PLOS ONE. 2014;9(12):e115453
- Article: JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN. 2013;23(4):276-281
- Article: WORLD HEALTH & POPULATION. 2012;14(1):31-43
- Article: ZOONOSES AND PUBLIC HEALTH. 2012;59(5):330-338
- Article: BMC INFECTIOUS DISEASES. 2012;12:155
- Article: HEALTH AND QUALITY OF LIFE OUTCOMES. 2012;10:53
- Article: PLOS ONE. 2012;7(10):e47000
- Article: PLOS ONE. 2012;7(8):e37590
- Article: BMC PUBLIC HEALTH. 2011;11:705
- Article: AFRICAN JOURNAL OF REPRODUCTIVE HEALTH. 2011;15(2):45-55
- Article: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. 2011;14:20
- Article: ASIA EUROPE JOURNAL. 2011;8(4):485-497
- Article: BMC PUBLIC HEALTH. 2011;11:151
- Article: BMC INFECTIOUS DISEASES. 2011;11:32
- Article: PLOS ONE. 2010;5(10):e13613
- Article: ARCHIVES OF MEDICAL RESEARCH. 2008;39(7):682-685
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All other publications
- Review: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE. 2021;2021:5585239-12
- Review: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE. 2020;2020:2034625
- Editorial comment: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 2010;53(3):283-284
- Letter: ARCHIVES OF MEDICAL RESEARCH. 2009;40(1):65
Employments
- Researcher, Department of Global Public Health, Karolinska Institutet, 2018-
Degrees and Education
- Docent, Karolinska Institutet, 2017