Fredrik Wermeling

Fredrik Wermeling

Principal Researcher | Docent
Visiting address: D2:01, Karolinska Universitetssjukhuset, 17177 Stockholm
Postal address: K2 Medicin, Solna, K2 Reuma Wermeling F, 171 77 Stockholm

About me

  • Using experimental systems and patient material we study the immune system
    with a specific interest related to inflammation, autoimmune disease and
    A major part of the different projects in the lab involves using CRISPR-based
    custom screens as a discovery platform to understand complex biological
    processes and to identify novel drug targets.
    Currently several projects in the lab relates to our interest in signaling
    downstream of the IL-4 receptor (IL-4R). The basis for this interest was the
    unexpected finding that the expression of the IL-4R on myeloid cells is
    essential for the activity of a drug (IVIG) used to treat patients with
    autoimmune disease, and that this receptor is highly regulated during
    inflammation (Anthony et al, 2011, Nature and Wermeling et al, 2013, PNAS).
    The Wermeling Laboratory is located at the Center for Molecular Medicine
    (CMM), Karolinska University Hospital, Solna, Sweden. The group is part of
    the Devision of Rheumatology, Department of Medicine, Karolinska Institutet,
    Wenner-Gren fellow, 2010
    Ingvar Carlsson Award (SSF), 2013
    Senior Investigator Award from Swedish Cancer Foundation, 2022


  • More than 200h teaching in several KI programs, including Medical, Optometry,
    Biomedicine, and various master programs and PhD courses.


All other publications


  • Principal Researcher, Department of Medicine, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2021
  • Degree Of Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2010
  • Master Of Medical Science, Karolinska Institutet, 2009

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