Filip Segerberg

Publications
CV
Public outreach and news

Articles

Article: JOURNAL OF IMMUNOLOGY. 2024;212(5):868-880
KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity
Leijonhufvud C; Sanz-Ortega L; Schlums H; Gaballa A; Andersson A; Eriksson C; Segerberg F; Uhlin M; Bryceson YT; Carlsten M
Article: LEUKEMIA. 2023;37(9):1830-1841
Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells
Palau A; Segerberg F; Lidschreiber M; Lidschreiber K; Naughton AJ; Needhamsen M; Jung LA; Jagodic M; Cramer P; Lehmann S; Carlsten M; Lennartsson A
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(10):e1346
LIR-1 educates expanded human NK cells and defines a unique antitumor NK cell subset with potent antibody-dependent cellular cytotoxicity
Leijonhufvud C; Reger R; Segerberg F; Theorell J; Schlums H; Bryceson YT; Childs RW; Carlsten M
Article: METHODS IN MOLECULAR BIOLOGY. 2020;2121:213-239
CRISPR/Cas9-Based Gene Engineering of Human Natural Killer Cells: Protocols for Knockout and Readouts to Evaluate Their Efficacy.
Lambert M; Leijonhufvud C; Segerberg F; Melenhorst JJ; Carlsten M
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1262
Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4^R334X
Levy E; Reger R; Segerberg F; Lambert M; Leijonhufvud C; Baumer Y; Carlsten M; Childs R
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2164
Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness
Segerberg F; Lundtoft C; Reid S; Hjorton K; Leonard D; Nordmark G; Carlsten M; Hagberg N

All other publications

Letter: HEMASPHERE. 2023;7(11):e974
Improved Leukemia Clearance After Adoptive Transfer of NK Cells Expressing the Bone Marrow Homing Receptor CXCR4^R334X
Segerberg F; Lambert M; Sanz-Ortega L; Andersson A; Childs RW; Carlsten M
Doctoral thesis: 2023
Improving NK cell-based immunotherapy of cancer by exploration of migration and inhibitory receptor-ligand interactions
Segerberg F

Employments

Clinical Assistant, Department of Laboratory Medicine, Karolinska Institutet, 2025-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2023
Degree Of Master Of Science In Medicine, Karolinska Institutet, 2018

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