Federica Giammarino

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About me

Federica received her Ph.D. in 2023 at the Department of Medical Biotechnology, University of Siena, Italy, on the in vitro characterization of novel antivirals for the treatment of multidrug resistant HIV-1, flaviviruses and coronaviruses. She joined us as postdoctoral researcher in October 2023. Her research focuses on the in vitro and ex vivo evaluation of compounds for the regulation of HIV latency/replication and on the role of biomaterials in combination with antiviral compounds as treatment and prophylaxis against sexually transmitted infections.

Articles

Journal article: SCIENTIFIC REPORTS. 2025;15(1):28197
Harnessing prebiotic formamide chemistry: a novel platform for antiviral exploration.
Martina MG; Vagaggini C; Dreassi E; De Angelis M; Nencioni L; Dragoni F; Giammarino F; Boccuto A; Zazzi M; Vicenti I; Radi M
Journal article: ANTIVIRAL RESEARCH. 2025;239:106157
Combined doravirine and islatravir cooperate to inhibit NRTI and NNRTI resistant HIV-1 in vitro
Giammarino F; Paletti C; Bartolini N; Fiaschi L; Biba C; Varasi I; Foca E; Gulminetti R; Ferrara M; Comi L; Vicenti I; Castagna A; Zazzi M; Saladini F
Journal article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2024;277:116737
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization.
Bonomini A; Felicetti T; Pacetti M; Bertagnin C; Coletti A; Giammarino F; De Angelis M; Poggialini F; Macchiarulo A; Sabatini S; Mercorelli B; Nencioni L; Vicenti I; Dreassi E; Cecchetti V; Tabarrini O; Loregian A; Massari S
Journal article: JOURNAL OF MEDICAL VIROLOGY. 2024;96(8):e29832
Regaining virological suppression in a woman living with a six-class resistant HIV by combining injectable antiretroviral drugs guided by genotypic and phenotypic tests
Monti B; Soria A; Saladini F; Lapadula G; Squillace N; Giammarino F; Paletti C; Bartolini N; Spagnuolo V; Castagna A; Zazzi M; Bonfanti P
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;229(6):1796-1802
Prevalence and Phenotypic Susceptibility to Doravirine of the HIV-1 Reverse Transcriptase V106I Polymorphism in B and Non-B Subtypes.
Giammarino F; de Salazar A; Malet I; Viñuela L; Fuentes A; Saladini F; Bartolini N; Charpentier C; Lambert-Niclot S; Sterrantino G; Colao MG; Micheli V; Bertoli A; Fabeni L; Teyssou E; Delgado R; Falces-Romero I; Aguilera A; Gomes P; Paraskevis D; Santoro MM; Ceccherini-Silberstein F; Marcelin A-G; Moreno C; Zazzi M; García F
Article: NEW MICROBIOLOGICA. 2024
PRESTIGIO RING "a 59-year-old man with multidrug resistant HIV-1 infection failing a regimen including dolutegravir, rilpivirine, atazanavir/cobicistat: successful treatment tailoring based on genotypic and phenotypic resistance tests"
Panza F; Saladini F; Bartolini N; Giammarino F; Montagnani F; Spagnuolo V; Tumbarello M; Santoro MM; Castagna A; Zazzi M; Fabbiani M
Article: MOLECULES. 2024;29(7):1452
Serendipitous Identification of Azine Anticancer Agents Using a Privileged Scaffold Morphing Strategy
Cesarini S; Vicenti I; Poggialini F; Filippi S; Mancin E; Fiaschi L; De Marchi E; Giammarino F; Vagaggini C; Bizzarri BM; Saladino R; Dreassi E; Zazzi M; Botta L
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2024;22(4):767-783
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines
Pacetti M; Pismataro MC; Felicetti T; Giammarino F; Bonomini A; Tiecco M; Bertagnin C; Barreca ML; Germani R; Cecchetti V; Vicenti I; Tabarrini O; Zazzi M; Loregian A; Massari S
Article: VIRUSES-BASEL. 2024;16(2):168
In Vitro Combinatorial Activity of Direct Acting Antivirals and Monoclonal Antibodies against the Ancestral B.1 and BQ.1.1 SARS-CoV-2 Viral Variants.
Fiaschi L; Biba C; Varasi I; Bartolini N; Paletti C; Giammarino F; Saladini F; Zazzi M; Vicenti I
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2024;14:1334126
Broad synergistic antiviral efficacy between a novel elite controller-derived dipeptide and antiretrovirals against drug-resistant HIV-1
Giammarino F; Sonnerborg A; Cena-Diez R
Article: CHEMMEDCHEM. 2023;18(16):e202300200
Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties.
Grazia Martina M; Giammarino F; Vicenti I; Groaz E; Rozenski J; Incerti M; Sannio F; Docquier JD; Zazzi M; Radi M
Article: PHARMACEUTICALS. 2023;16(8):1118
HIV-1 Integrase Inhibition Activity by Spiroketals Derived from Plagius flosculosus, an Endemic Plant of Sardinia (Italy) and Corsica (France).
Sanna C; D'Abrosca B; Fiorentino A; Giammarino F; Vicenti I; Corona A; Caredda A; Tramontano E; Esposito F
Article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2023;61(3):106737
Residual phenotypic susceptibility to doravirine in multidrug-resistant HIV-1 from subjects enrolled in the PRESTIGIO Registry
Saladini F; Giammarino F; Maggiolo F; Ferrara M; Cenderello G; Celesia BM; Martellotta F; Spagnuolo V; Corbelli GM; Gianotti N; Santoro MM; Rusconi S; Zazzi M; Castagna A
Article: MOLECULES. 2022;27(24):8829
Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity
Cesarini S; Vicenti I; Poggialini F; Secchi M; Giammarino F; Varasi I; Lodola C; Zazzi M; Dreassi E; Maga G; Botta L; Saladino R
Article: JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES. 2022;91(4):381-389
Dynamics of Total and Intact HIV-1 DNA in Virologically Suppressed Patients Switching to DTG-Based or ATV-Based Dual Therapy
Dragoni F; Rossetti B; Lombardi F; Raffaelli CS; Bartolini N; Giammarino F; Moschese D; Di Giambenedetto S; Fabbiani M; De Luca A; Vicenti I; Zazzi M; Saladini F
Article: VACCINES. 2022;10(8):1237
Long-Term Longitudinal Analysis of Neutralizing Antibody Response to Three Vaccine Doses in a Real-Life Setting of Previously SARS-CoV-2 Infected Healthcare Workers: A Model for Predicting Response to Further Vaccine Doses
Parisi SG; Mengoli C; Basso M; Vicenti I; Gatti F; Scaggiante R; Fiaschi L; Giammarino F; Iannetta M; Malagnino V; Zago D; Dragoni F; Zazzi M
Article: VIRUSES-BASEL. 2022;14(7):1374
Efficacy of Licensed Monoclonal Antibodies and Antiviral Agents against the SARS-CoV-2 Omicron Sublineages BA.1 and BA.2
Fiaschi L; Dragoni F; Schiaroli E; Bergna A; Rossetti B; Giammarino F; Biba C; Gidari A; Lai A; Nencioni C; Francisci D; Zazzi M; Vicenti I
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(5):2670
Sofosbuvir Selects for Drug-Resistant Amino Acid Variants in the Zika Virus RNA-Dependent RNA-Polymerase Complex In Vitro
Boccuto A; Dragoni F; Picarazzi F; Lai A; Della Ventura C; Veo C; Giammarino F; Saladini F; Zehender G; Zazzi M; Mori M; Vicenti I
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2021;76(1):130-134
In vitro cross-resistance to doravirine in a panel of HIV-1 clones harbouring multiple NNRTI resistance mutations
Saladini F; Giammarino F; Hosseini BA; Giannini A; Boccuto A; Dragoni F; Vicenti I; Shafer RW; Zazzi M
Article: SLAS DISCOVERY. 2020;25(5):506-514
Development of a Cell-Based Immunodetection Assay for Simultaneous Screening of Antiviral Compounds Inhibiting Zika and Dengue Virus Replication
Vicenti I; Dragoni F; Giannini A; Giammarino F; Spinicci M; Saladini F; Boccuto A; Zazzi M
Article: ANTIVIRAL RESEARCH. 2020;175:104708
Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro
Dragoni F; Boccuto A; Picarazzi F; Giannini A; Giammarino F; Saladini F; Mori M; Mastrangelo E; Zazzi M; Vicenti I
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