Evangelos Tzoras

Publications
Public outreach and news

Articles

Article: JAMA NETWORK OPEN. 2025;8(7):e2518906
Pathologist-Read vs AI-Driven Assessment of Tumor-Infiltrating Lymphocytes in Melanoma
Aung TN; Liu M; Su D; Shafi S; Boyaci C; Steen S; Tsiknakis N; Vidal JM; Maher N; Micevic G; Tan SX; Vesely MD; Nourmohammadi S; Bai Y; Djureinovic D; Wong PF; Bates K; Chan NNN; Gavirelatou N; He M; Burela S; Barna R; Bosic M; Braeutigam K; Illabochaca I; Zhou C; Gama J; Kreis B; Mohacsi R; Pillar N; Pinto J; Poulios C; Toli MA; Tzoras E; Bracero Y; Bosisio F; Cserni G; Dema A; Fortarezza F; Gonzalez MS; Gullo I; Queipo Gutierrez FJ; Hacihasanoglu E; Jovic V; Lazar B; Olinca M; Neppl C; Oliveira RC; Pezzuto F; Gomes Pinto D; Plotar V; Pop O; Rau T; Skok K; Sun W; Serbes ED; Solass W; Stanowska O; Szasz M; Szymonski K; Thimm F; Vignati D; Vigdorovits A; Prieto V; Sinnberg T; Wilmott J; Cowper S; Warrell J; Saenger Y; Hartman J; Plummer J; Osman I; Rimm DL; Acs B
Journal article: CLINICAL CANCER RESEARCH. 2025;31(12_Supplement):p2-01-30-p2-01-30
Abstract P2-01-30: Gene Expression patterns in early ER+/HER2- breast cancer treated with neoadjuvant chemotherapy versus CDK4/6 inhibitor therapy: results from the Swedish PREDIX Luminal B trial
Tzoras E; Sarafidis M; Sifakis EG; Salgkamis D; Acs B; Sun W; Zerdes I; Wang K; Bergh J; Hatschek T; Matikas A; Foukakis T
Journal article: CLINICAL CANCER RESEARCH. 2025;31(12_Supplement):p1-02-28-p1-02-28
Abstract P1-02-28: PDGFRa+/FAP- fibroblasts at multiplex in situ resolution are associated with resistance to HER2 blockade in neoadjuvant treated HER2+ breast cancer: results from the Swedish PREDIX HER2 trial
Manikis G; Tzoras E; Tsiknakis N; Bernabe AM; Zhu Y; Wang K; Zerdes I; Bergh J; Hatschek T; Östman A; Matikas A; Foukakis T
Journal article: ESMO OPEN. 2025;10:104584
30P Novel integrated tumor micro-/macro-environment (TMME) subtypes for prediction of treatment response to neoadjuvant anti-HER2 therapy
Zerdes I; Wang K; Manikis G; Salgkamis D; Zhu Y; Tzoras E; Mezheyeuski A; Acs B; Sifakis EG; Hartman J; Papakonstantinou A; Matikas A; Bergh J; Hatschek T; Foukakis T
Journal article: ESMO OPEN. 2025;10:104559
4MO Development and validation of CDKPredX, a novel predictor of response to neoadjuvant endocrine therapy and CDK4/6 inhibitors versus chemotherapy in ER+/HER2- breast cancer: Correlative analysis of the randomized phase II PREDIX luminal B trial
Foukakis T; Tzoras E; Sarafidis M; Sifakis EG; Salgkamis D; Zerdes I; Wang K; Pascual T; Gavilá-Gregori J; Villacampa G; Prat A; Perou CM; Bergh J; Hatschek T; Matikas A
Journal article: ESMO OPEN. 2025;10:104632
78P Validation of an AI-based solution for breast cancer risk stratification using digital H&E images: Subgroup analysis within PANTHER clinical trial
Tzoras E; Salgkamis D; Tsiknakis N; Johansson H; Sun W; Hellström M; Andersson A; Loibl S; Untch M; Denkert C; Jank P; Rantalainen M; Hartman J; Zerdes I; Matikas A; Bergh J; Foukakis T
Journal article: ESMO OPEN. 2025;10:104589
35P Deep learning for overall survival risk prediction in early breast cancer using H&E-stained images and clinicopathological variables
Tsiknakis N; Salgkamis D; Tzoras E; Manikis G; Liu X; Marias K; Acs B; Hartman J; Hellström M; Johansson H; Andersson A; Loibl S; Untch M; Denkert C; Jank P; Zerdes I; Matikas A; Bergh J; Foukakis T
Journal article: ESMO OPEN. 2025;10:104631
77P The landscape of somatic mutations in high-risk early ER+/HER2- breast cancer patients: Analysis of the randomized phase II PREDIX luminal B trial
Sarafidis M; Tzoras E; Sifakis EG; Wang K; Salgkamis D; Zerdes I; Bergh J; Hatschek T; Matikas A; Foukakis T
Article: INTERNATIONAL JOURNAL OF CANCER. 2025;156(8):1621-1633
Prognostic and predictive implications of sterile alpha motif and HD domain-containing protein 1 (SAMHD1) expression in breast cancer
Kouvaraki M; Zerdes I; Sifakis EG; Sarafidis M; Matikas A; Tzoras E; Kjallquist U; Stathopoulou K; Lovrot J; Alkodsi A; Hartman J; Sotiriou C; Richard F; Hatschek T; Herold N; Bergh J; Rassidakis GZ; Foukakis T
Article: IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS. 2024;28(9):5312-5322
Unveiling the Power of Model-Agnostic Multiscale Analysis for Enhancing Artificial Intelligence Models in Breast Cancer Histopathology Images
Tsiknakis N; Manikis G; Tzoras E; Salgkamis D; Vidal JM; Wang K; Zaridis D; Sifakis E; Zerdes I; Bergh J; Hartman J; Acs B; Marias K; Foukakis T
Article: ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY. IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY. ANNUAL INTERNATIONAL CONFERENCE. 2024;2024:1-5
Ensuring Model Fairness via Stratified Training: TP53 Mutation Prediction with Estrogen Receptor Stratification in Breast Histopathology.
Tsiknakis N; Wang K; Salgkamis D; Tzoras E; Manikis GC; Sifakis E; Bergh J; Zerdes I; Marias K; Matikas A; Foukakis T
Article: ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY. IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY. ANNUAL INTERNATIONAL CONFERENCE. 2023;2023:1-4
Multiresolution Self-Supervised Feature Integration via Attention Multiple Instance Learning for Histopathology Analysis
Tsiknakis N; Tzoras E; Zerdes I; Manikis GC; Acs B; Hartman J; Hatschek T; Foukakis T; Marias K
Journal article: HEMASPHERE. 2019;3(S1):106-107
PF308 PROGNOSTIC FACTORS AND IMMUNOHISTOCHEMICAL PROFILE IN PRIMARY REFRACTORY AND RECURRENT DIFFUSE LARGE B‐CELL LYMPHOMAS
Lampikoski H; Drakos E; Nummisalo E; Tzoras E; Kokaraki G; Harrysson S; Smedby KE; Rassidakis G

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Conference publication: ESMO OPEN. 2024;9:103110
122P Primary results and biomarker analysis from PREDIX LumB: A prospective randomized phase II trial investigating sequence of neoadjuvant chemotherapy and palbociclib/endocrine therapy for luminal breast cancer
Matikas A; Bjöhle J; Barnekow E; Isakssonfriman E; Zouzos A; Tzoras E; Johansson H; Margolin S; Acs B; Boyaci C; Sun W; Zerdes I; Kessler LE; Grybäck P; Hellström M; Hartman J; Brandberg Y; Bergh J; Hatschek T; Foukakis T
Conference publication: ESMO OPEN. 2024;9:103075
69P Deep learning prognostication through prediction of TP53 gene mutation status on breast cancer hematoxylin and eosin slides
Tsiknakis N; Salgkamis D; Tzoras E; Wang K; Liu X; Manikis G; Sifakis EG; Bergh J; Marias K; Zerdes I; Matikas A; Foukakis T
Meeting abstract: CANCER RESEARCH. 2023;83(5):p2-21-02-p2-21-02
Longitudinal tumor-immune microenvironment changes in patients with clinical luminal A early breast cancer treated with neoadjuvant palbociclib and endocrine therapy: results from the Swedish randomized PREDIX Luminal A trial
Zerdes I; Salgkamis D; Matikas A; Selander L; Wang K; Tzoras E; Sifakis E; Agartz S; Chen X; Hellstrom M; Hartman J; Bergh J; Foukakis T; Hatschek T
Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(16_suppl):e12620
Tumor-infiltrating lymphocytes (TILs) dynamics in breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis.
Zerdes I; Zhu Y; Tzoras E; Matikas A; Bergh JCS; Valachis A; Foukakis T
Review: CANCERS. 2022;14(8):1999
Dissecting Tumor-Immune Microenvironment in Breast Cancer at a Spatial and Multiplex Resolution
Tzoras E; Zerdes I; Tsiknakis N; Manikis GC; Mezheyeuski A; Bergh J; Matikas A; Foukakis T
Review: FRONTIERS IN ONCOLOGY. 2022;12:999843
Expression patterns and prognostic implications of tumor-infiltrating lymphocytes dynamics in early breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis
Zhu Y; Tzoras E; Matikas A; Bergh J; Valachis A; Zerdes I; Foukakis T
Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(16)
Tumor-infiltrating lymphocytes (TILs) dynamics in breast cancer patients receiving neoadjuvant therapy: A systematic review and meta-analysis.
Zerdes I; Zhu Y; Tzoras E; Matikas A; Bergh JCS; Valachis A; Foukakis T
Meeting abstract: BLOOD. 2018;132:4130
The Novel Tumor Suppressor SAMHD1 Is Differentially Expressed and Partly Regulated By MYC in Peripheral T-Cell Lymphomas (PTCL)
Da Silva PFN; Tsesmetzis N; Xagoraris I; Wasik AM; Kokaraki G; Tzoras E; Osterborg A; Sander B; Herold N; Rassidakis G

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