Erik Johan Eliasson

Publications
CV
Public outreach and news

Articles

Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2026;81(5):dkag116
Optimizing cloxacillin prophylaxis in hip and knee arthroplasty based on population pharmacokinetics of unbound plasma concentrations
Beijer G; Wallander K; Soderquist B; Giske CG; Breuer O; Eriksen J; Eliasson E
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2026;81(3):dkag067
Is current guidance for cloxacillin prophylaxis dosages in hip and knee arthroplasty adequate? Evidence from a prospective Swedish cohort
Wallander K; Beijer G; Eliasson E; Giske CG; Ponzer S; Soderquist B; Eriksen J
Article: ACTA ONCOLOGICA. 2025;64:848-856
CYP2D6 genotype and outcome in tamoxifen treated early breast cancer
Thoren L; Lindh JD; Molden E; Kringen MK; Bergh J; Eliasson E; Margolin S
Article: CRITICAL CARE. 2025;29(1):208
First dose target attainment with extended infusion regimens of piperacillin and meropenem
Beijer G; Swartling M; Nielsen EI; Breuer O; Giske CG; Eliasson E; Petersson J
Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2025;117(4):629-636
Influence of endoxifen on mammographic density: results from the KARISMA-Tam trial
Hammarstrom M; Gabrielson M; Bergqvist J; Lundholm C; Crippa A; Backlund M; Wengstrom Y; Borgquist S; Eliasson E; Eriksson M; Tapia J; Czene K; Hall P
Article: NUCLEIC ACIDS RESEARCH. 2025;53(D1):D1498-D1509
PharmFreq: a comprehensive atlas of ethnogeographic allelic variation in clinically important pharmacogenes
Tremmel R; Zhou Y; Camara MD; Laarif S; Eliasson E; Lauschke VM
Article: BREAST CANCER RESEARCH AND TREATMENT. 2023;198(3):499-508
Adherence to endocrine therapy in early breast cancer in relation to Cytochrome P450 2D6 genotype: a comparison between pharmacy dispensation data and medical records
Thoren L; Margolin S; Eliasson E; Bergh J; Lindh JD
Article: HUMAN GENOMICS. 2023;17(1):15
Global distribution of functionally important CYP2C9 alleles and their inferred metabolic consequences
Zhou Y; Nevosadova L; Eliasson E; Lauschke VMM
Article: THERAPEUTIC DRUG MONITORING. 2023;45(1):45-54
Reproducible Quantification of Unbound Fractions of Four Beta-Lactam Antibiotics: Ultrafiltration Versus Microdialysis of Spiked Healthy Donor Plasma
Beijer G; Clarin L; oestervall J; Barclay V; Eliasson E
Article: SCIENTIFIC REPORTS. 2022;12(1):21891
Low attainment to PK/PD-targets for β-lactams in a multi-center study on the first 72 h of treatment in ICU patients
Smekal A-K; Furebring M; Eliasson E; Lipcsey M
Article: BREAST CANCER RESEARCH AND TREATMENT. 2021;190(3):451-462
Impact of systemic adjuvant therapy and CYP2D6 activity on mammographic density in a cohort of tamoxifen-treated breast cancer patients
Thoren L; Eriksson M; Lindh JD; Czene K; Bergh J; Eliasson E; Hall P; Margolin S
Article: ANNALS OF ONCOLOGY. 2021;32(10):1286-1293
CYP2D6 genotype predicts tamoxifen discontinuation and drug response: a secondary analysis of the KARISMA trial
He W; Eriksson M; Eliasson E; Grassmann F; Backlund M; Gabrielson M; Hammarstrom M; Margolin S; Thoren L; Wengstrom Y; Borgquist S; Hall P; Czene K
Article: LAKARTIDNINGEN. 2021;118:20176
[Pharmacogenomics - a cornerstone of Precision Medicine. Genomic Medicine Sweden analyses genotypes associated with serious drug toxicity or therapeutic failure].
Eliasson E; Wadelius M
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2021;65(4):e02029-e02020
Poor Correlation between Meropenem and Piperacillin Plasma Concentrations and Delivered Dose of Continuous Renal Replacement Therapy
Petersson J; Giske CG; Eliasson E
Article: EUROPEAN RESPIRATORY JOURNAL. 2021;57(3):2003463
Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China.
Davies Forsman L; Niward K; Kuhlin J; Zheng X; Zheng R; Ke R; Hong C; Werngren J; Paues J; Simonsson USH; Eliasson E; Hoffner S; Xu B; Alffenaar J-W; Schön T; Hu Y; Bruchfeld J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2021;77(3):409-419
Bleeding and thromboembolism due to drug-drug interactions with non-vitamin K antagonist oral anticoagulants-a Swedish, register-based cohort study in atrial fibrillation outpatients
Holm J; Mannheimer B; Malmstrom RE; Eliasson E; Lindh JD
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2021;87(3):1243-1252
Impairment of endoxifen formation in tamoxifen-treated premenopausal breast cancer patients carrying reduced-function CYP2D6 alleles
Thoren L; Lindh JD; Ackehed G; Kringen MK; Hall P; Bergh J; Molden E; Margolin S; Eliasson E
Article: PHARMACOGENOMICS JOURNAL. 2020;20(4):579-585
SWEDEGENE-a Swedish nation-wide DNA sample collection for pharmacogenomic studies of serious adverse drug reactions
Hallberg P; Yue Q-Y; Eliasson E; Melhus H; As J; Wadelius M
Journal article: THERAPEUTIC DRUG MONITORING. 2020;42(3):353
In Memoriam: Professor Folke Sjoqvist
Christians U; Henthorn TK; Walson PD; Oellerich M; Eliasson E
Article: JOURNAL OF CLINICAL ONCOLOGY. 2020;38(6):548-557
CYP2D6 Genotype Predicts Tamoxifen Discontinuation and Prognosis in Patients With Breast Cancer
He W; Grassmann F; Eriksson M; Eliasson E; Margolin S; Thoren L; Hall P; Czene K
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All other publications

Study protocol: BMJ OPEN. 2026;16(4):e109745
Unbound cloxacillin plasma concentrations in relation to toxicity and renal function: protocol for a prospective, observational clinical trial in a real-world Staphylococcus aureus bacteraemia population
Damgaard T; Hellborg T; Larsson A; Eliasson E; Bonnedahl J; Nielsen EI; Schon T; Hallgren A
Review: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2024;416(26):5565-5577
Development and clinical implementation of an LC-HRMS method for ivacaftor, lumacaftor, tezacaftor and elexacaftor in human plasma and breast milk.
Hansson AB; Wadström H; Eliasson E; Al Shakirchi M; de Monestrol I; Barclay V
Letter: LAKARTIDNINGEN. 2024;121:151
Nya rekommendationer för infusion av betalaktamantibiotika.
Gustafsson T; Eliasson E; Furebring M; Nielsen E; Petersson J; von Seth M; Tängden T
Review: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2022;131(6):452-464
A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing
Zhou Y; Koutsilieri S; Eliasson E; Lauschke VM
Other: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2020;108(6):1127-1128
Tribute to Folke Sjoqvist, a Pioneer in Clinical Pharmacology
Dahl M-L; Bergman U; Bertilsson L; Eliasson E; Gustafsson LL; Panagiotidis G; Rane A
Study protocol: BMJ OPEN. 2018;8(9):e023899
Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study
Forsman LD; Niward K; Hu Y; Zheng R; Zheng X; Ke R; Cai W; Hong C; Li Y; Gao Y; Werngren J; Paues J; Kuhlin J; Simonsson USH; Eliasson E; Alffenaar J-W; Mansjo M; Hoffner S; Xu B; Schon T; Bruchfeld J
Letter: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2017;121(4):215-216
Reply to "Multiple and Opposite Effects of Angiotensin II Receptor Blockers on the Bioavailability of Epoxyeicosatrienoic Acids'
Senda A; Mukai Y; Hayakawa T; Kato Y; Eliasson E; Rane A; Toda T; Inotsume N
Review: LAKARTIDNINGEN. 2015;112:CW3P
[Beta lactam antibiotics and the question of dose regimen for severe infection. Prolonged infusion theoretically appealing--yet no evidence of clinical benefit].
Leander G; Eliasson E; Hanberger H; Giske C
Review: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2013;45(3):161-175
Rational use of aminoglycosides-Review and recommendations by the Swedish Reference Group for Antibiotics (SRGA)
Hanberger H; Edlund C; Furebring M; Giske CG; Melhus A; Nilsson LE; Petersson J; Sjolin J; Ternhag A; Werner M; Eliasson E
Editorial: PHARMACOGENOMICS. 2012;13(16):1887-1891
Karolinska Institutet
Eliasson E; Sim SC; Rane A; Ingelman-Sundberg M
Letter: PHARMACOGENOMICS. 2012;13(14):1561-1562
Influence of the CYP2C9*3 allele on the pharmacological interaction between warfarin and simvastatin: author reply
Andersson ML; Eliasson E; Lindh JD
Review: JOURNAL OF INTERNAL MEDICINE. 2010;268(6):540-548
Drug-drug interactions that reduce the formation of pharmacologically active metabolites: a poorly understood problem in clinical practice
Mannheimer B; Eliasson E
Letter: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2009;65(10):1055
Severely diminished response to vitamin K-treatment for self-inflicted warfarin intoxication in a patient genotyped as CYP2C9*3*3
Backstrom T; Barkman G; Lindh JD; Eliasson E
Published conference paper: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2007;81(6):899-902
The convergence of conventional therapeutic drug monitoring and pharmacogenetic testing in personalized medicine:: Focus on antidepressants
Sjoqvist F; Eliasson E
Letter: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2006;80(3):301-302
Is celecoxib an inducer of cytochrome P450 3A4 in subjects carrying the CYP2C9*3 allele? Reply
Eliasson E; Lundblad MS
Editorial: BMJ-BRITISH MEDICAL JOURNAL. 2006;332(7551):1163-1164
Ethnicity and adverse drug reactions - Personalised drug treatment is getting closer but will not replace good clinical judgment
Eliasson E
Letter: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2006;79(3):287-288
Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9*3
Lundblad MS; Ohlsson S; Johansson P; Lafolie P; Eliasson E
Published conference paper: DRUG METABOLISM AND DISPOSITION. 2004;32(5):484-489
The impact of CYP2C9 genetics and oral contraceptives on cytochrome P4502C9 phenotype
Sandberg M; Johansson I; Christensen M; Rane A; Eliasson E
Review: DRUG METABOLISM AND DISPOSITION. 2002;30(10):1053-1058
Reactive intermediates and the dynamics of glutathione transferases
Rinaldi R; Eliasson E; Swedmark S; Morgenstern R
Letter: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2002;54(2):183-185
Intra-individual variability in urinary losartan oxidation ratio, an in vivo marker of CYP2C9 activity
Yasar Ü; Dahl ML; Christensen M; Eliasson E
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Employments

Professor/Senior Physician, Pharmacogenetics, Department of Laboratory Medicine, Karolinska Institutet, 2012-

Degrees and Education

Docent, Karolinska Institutet, 2000
University Medical Degree, Karolinska Institutet, 1994

Articles

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