Enikö Sonkoly

Enikö Sonkoly

Senior Lecturer | Docent
Visiting address: CMM, L8:02, Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K2 Medicin, Solna, K2 Derm o Ven Sonkoly E, 171 77 Stockholm
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About me

  • Current position: Associate professor in Dermatology
    • Inflammation Europe ASPIRE 2014 research award (Pfizer) (2014) •
    “Future Leaders in Dermatology” Award from the European Society for
    Dermatological Research (2011) • MSD Dermatologistipendium (2011) •
    Schering-Ploughs Immunologistipendium (2009) • Fellowship of the
    Wenner-Gren Foundations for foreign postdoctoral researchers (2006) • Award
    of the “Fekete Zoltan” Foundation of the Hungarian Society for
    Dermatology (2005)
    2002-2005: PhD in immunology, Department of Dermatology,
    University of Szeged, Szeged, Hungary
  • Title of the dissertation:
    Identification and characterization of a novel
    psoriasis-susceptibility-related, non-coding RNA gene, PRINS
    1999-2002: Semmelweis University, Faculty of Medicine, Budapest,
    Hungary
  • MD
    1996-1999: University of Szeged, Faculty of Medicine, Szeged,
    Hungary

Research

  • My main scientific focus is to explore the role of a class of non-coding
    RNAs, microRNAs (miRNAs) in psoriasis, to understand their roles in
    regulatory pathways underlying chronic skin inflammation and to explore their
    potential to become therapeutic targets and biomarkers for psoriasis.
    Psoriasis is a common chronic inflammatory skin disease, considered as a
    systemic inflammatory disease with significant comorbidities.
    Results from our lab strongly implicate miRNAs in the pathogenesis of
    psoriasis. We are currently investigating the function and therapeutic
    potential of miRNAs in psoriasis by (1) in vivo functional studies of
    psoriasis-associated miRNAs, (2) exploring psoriasis-associated pathways
    including miRNAs/ protein-coding transcripts (3) exploring possibilities of
    miRNA modulation for topical and systemic treatment. MiRNA modulation may be
    a promising approach for the treatment of psoriasis, or other inflammatory
    diseases, since miRNA modulation can affect entire pathways rather than
    single molecules, and miRNA inhibitors have been shown to be well-tolerated
    in human studies.
    Another main goal for my research is the identification of miRNA-based
    biomarkers, which are associated with clinical phenotypes of psoriasis and
    response to treatments. Prediction of treatment response and diagnosis of
    comorbidities in psoriasis patients represent an unmet medical need, and
    miRNAs present in the circulation are promising candidates as minimally
    invasive biomarkers.

Articles

All other publications

Employments

  • Senior Lecturer, Department of Medicine, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2011

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