Dimitrius Guimaraes

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CV
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Articles

Journal article: BIOCHEMISTRY AND BIOPHYSICS REPORTS. 2024;40:101831
The dose-effect response of combined red and infrared photobiomodulation on insulin resistance in skeletal muscle cells
Silva G; da Silva SS; Guimaraes DSPSF; da Cruz MV; Silveira LR; Rocha-Vieira E; Amorim FT; Magalhaes FDC
Article: SCIENCE TRANSLATIONAL MEDICINE. 2024;16(768):eado3022
Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes
Rizo-Roca D; Guimaraes DSPSF; Pendergrast LA; Di Leo N; Chibalin AV; Maqdasy S; Ryden M; Naslund E; Zierath JR; Krook A
Article: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE. 2024;15(4):1335-1347
Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6
Guimaraes DSPSF; Barrios NMF; de Oliveira AG; Rizo-Roca D; Jollet M; Smith JAB; Araujo TR; da Cruz MV; Marconato E; Hirabara SM; Vieira AS; Krook A; Zierath JR; Silveira LR
Journal article: MICROBIAL CELL FACTORIES. 2024;23(1):51
The recombinant l-lysine α-oxidase from the fungus Trichoderma harzianum promotes apoptosis and necrosis of leukemia CD34+hematopoietic cells
Costa MDN; Silva TA; Guimaraes DSPSF; Ricci-Azevedo R; Teixeira FR; Silveira LR; Gomes MD; Faca VM; de Oliveira EB; Calado RT; Silva RN
Journal article: PHOTOCHEMICAL AND PHOTOBIOLOGICAL SCIENCES. 2024;23(1):107-118
Antioxidant effects of LEDT in dystrophic muscle cells: involvement of PGC-1α and UCP-3 pathways
da Rocha GL; Guimaraes DSPSF; da Cruz MV; Mizobuti DS; da Silva HNM; Pereira ECL; Silveira LR; Minatel E
Journal article: AMINO ACIDS. 2023;55(7):913-929
The first evidence of biological activity for free Hypusine, an enigmatic amino acid discovered in the '70s
Tamborlin L; Pereira KD; Guimaraes DSPSF; Silveira LR; Luchessi AD
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(6):104702
Interaction between poly(A)-binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response.
Oliveira AG; Oliveira LD; Cruz MV; Guimarães DSPSF; Lima TI; Santos-Fávero BC; Luchessi AD; Pauletti BA; Leme AP; Bajgelman MC; Afonso J; Regitano LCA; Carvalho HF; Carneiro EM; Kobarg J; Perissi V; Auwerx J; Silveira LR
Journal article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2022;928:175122
Rosiglitazone protects INS-1E cells from human islet amyloid polypeptide toxicity
Marmentini C; Guimaraes DSPSF; de LTI; Teofilo FBS; da Silva NS; Soares GM; Boschero AC; Kurauti MA
Journal article: EUROPEAN JOURNAL OF NUTRITION. 2022;61(3):1699-1700
Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway (vol 60, pg 3947, 2021)
Alves BL; dos Reis Araujo T; Guimaraes DSPSF; Zoppi CC; Figueiredo MS; Carneiro EM
Journal article: EUROPEAN JOURNAL OF NUTRITION. 2021;60(7):3947-3957
Amino acid restriction alters survival mechanisms in pancreatic beta cells: possible role of the PI3K/Akt pathway
Alves BL; Araujo TDR; Guimaraes DSPSF; Zoppi CC; Figueiredo MS; Carneiro EM
Journal article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2021;535:111379
Effects of growth hormone-releasing hormone agonistic analog MR-409 on insulin-secreting cells under cyclopiazonic acid-induced endoplasmic reticulum stress
Rodrigues-dos-Santos K; Soares GM; Guimaraes DSPSF; Araujo TR; Vettorazzi JF; Zangerolamo L; Marconato-Junior E; Cai R; Sha W; Schally AV; Boschero AC; Barbosa HCL
Journal article: MOLECULAR METABOLISM. 2021;51:101226
The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition
Queiroz AL; Lessard SJ; Ouchida AT; Araujo HN; Goncalves DA; Guimaraes DSPSF; Teodoro BG; So K; Esprea EM; Hirshman MF; Alberici LC; Kettelhut IDC; Goodyear LJ; Silveira LR
Journal article: SAUDI PHARMACEUTICAL JOURNAL. 2021;29(9):1061-1069
Phytomodulatory proteins isolated from Calotropis procera latex promote glycemic control by improving hepatic mitochondrial function in HepG2 cells
de Oliveira KA; Araujo HN; de Lima TI; Oliveira AG; Favero-Santos BC; Guimaraes DSPSF; de Freitas PA; das Neves RDJ; Vasconcelos RP; Guimaraes de Almeida MG; Ramos MV; Silveira LR; de Oliveira AC
Journal article: LIVERS. 2021;1(4):201-220
Changes in PGC-1α-Dependent Mitochondrial Biogenesis Are Associated with Inflexible Hepatic Energy Metabolism in the Offspring Born to Dexamethasone-Treated Mothers
Campos CV; Teixeira CJ; Payolla TB; Crisma AR; Murata GM; Amaral AG; Pantaleao LC; Sodre FS; Onari MM; Almeida LDS; Pereira GA; Guimaraes DSSF; Silveira LR; Anhe GF; Bordin S
Journal article: FRONTIERS IN PHYSIOLOGY. 2021;12:676265
Intramuscular Injection of miR-1 Reduces Insulin Resistance in Obese Mice
Rodrigues AC; Spagnol AR; Frias FDT; de Mendonca M; Araujo HN; Guimaraes D; Silva WJ; Bolin AP; Murata GM; Silveira L
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2020;319(3):C541-C551
Regulation of Lin28a-miRNA let-7b-5p pathway in skeletal muscle cells by peroxisome proliferator-activated receptor delta
Araujo HN; Lima TI; Guimaraes DSPSF; Oliveira AG; Favero-Santos BC; Branco RCS; da Silva Araujo RM; Dantas AFB; Castro A; Chacon-Mikahil MPT; Minatel E; Geraldo MV; Carneiro EM; Rodrigues AC; Narkar VA; Silveira LR
Journal article: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2020;501:110661
MicroRNA miR-222 mediates pioglitazone beneficial effects on skeletal muscle of diet-induced obese mice
de Mendonca M; de Sousa E; da Paixao AO; dos Santos BA; Spagnol AR; Murata GM; Araujo HN; de Lima TI; Passos Simoes Froes Guimaraes DS; Silveira LR; Rodrigues AC
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(46):17249-17261
The pseudosubstrate inhibitor Acm1 inhibits the anaphase-promoting complex/cyclosome by combining high-affinity activator binding with disruption of Doc1/Apc10 function
Qin L; Mizrak A; Guimaraes DSPSF; Tambrin HM; Morgan DO; Hall MC
Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2019;143:203-208
Opposing action of NCoR1 and PGC-1α in mitochondrial redox homeostasis
Lima TI; Guimaraes DSPSF; Oliveira AG; Araujo H; Sponton CHG; Souza-Pinto NC; Saito A; Figueira ACM; Palameta S; Bajgelman MC; Calixto A; Pinto S; Mori MA; Orofino J; Perissi V; Mottis A; Auwerx J; Silveira LR
Journal article: JOURNAL OF PHYSIOLOGY. 2019;597(16):4277-4291
Essential role of the PGC-1α/PPARβ axis in Ucp3 gene induction
Lima TI; Guimaraes D; Sponton CH; Bajgelman MC; Palameta S; Toscaro JM; Reis O; Silveira LR
Journal article: THE FASEB JOURNAL. 2019;33:794.9
Characterization of the NCoR1 complex and its association with the molecular control of the mitochondrial biogenesis process
Silveira LR; Oliveira AG; Lima TI; Guimaraes DSP; Favero BC; Araujo HN; Araujo R
Journal article: TROPICAL PLANT PATHOLOGY. 2018;43(6):520-532
Differential expression and phytohormone unbalance in Citrus aurantifolia plants during "sudden decline of lime", a new phytoplasma disease of citrus
Alves MS; Silva FN; Guimaraes DSPSF; Vital CE; Vidigal PMP; Al-Mahmooli I; Al-Sadi AM; Carvalho CM
Journal article: PROTEIN EXPRESSION AND PURIFICATION. 2018;143:57-61
Expression, purification, and characterization of the TRIM49 protein
Guimaraes DS; Gomes MD
Journal article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2017;621:38-45
FBXO25 regulates MAPK signaling pathway through inhibition of ERK1/2 phosphorylation
Teixeira FR; Manfiolli AO; Vieira NA; Medeiros AC; Coelho PDO; Guimaraes DS; Schechtman D; Gomes MD
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2017;292(12):5125-5127
Substrate recognition by the Cdh1 destruction box receptor is a general requirement for APC/C^Cdh1-mediated proteolysis (vol 291, pg 15564, 2016)
Qin L; GuimaraES DSPSF; Melesse M; Hall MC
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(30):15564-15574
Substrate Recognition by the Cdh1 Destruction Box Receptor Is a General Requirement for APC/C^Cdh1-mediated Proteolysis
Qin L; Guimaraes DSPSF; Melesse M; Hall MC
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All other publications

Preprint: BIORXIV. 2024
Decreased sarcomeric mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin action in type 2 diabetes
Rizo-Roca D; Guimarães DS; Pendergrast LA; Di Leo N; Chibalin AV; Maqdasy S; Rydén M; Näslund E; Zierath JR; Krook A
Preprint: BIORXIV. 2023
Concerted regulation of skeletal muscle metabolism and contractile properties by the orphan nuclear receptor Nr2f6
Guimarães DSPSF; Barrios NMF; de Oliveira AG; Rizo-Roca D; Jollet M; Smith JAB; Araujo T; da Cruz MV; Junior EM; Hirabara S; Vieira A; Krook A; Zierath J; Silveira L
Conference publication: ACTA PHYSIOLOGICA. 2023;239
Sarcomeric mitochondrial creatine kinase 2 modulates mitochondrial homeostasis and is downregulated in men with type 2 diabetes
Rizo-Roca D; Guimaraes DS; Pendergrast L; Di Leo N; Naslund E; Zierath JR; Krook A
Book chapter: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2022;p. 293-303
The Taurine-Conjugated Bile Acid (TUDCA) Normalizes Insulin Secretion in Pancreatic β-Cells Exposed to Fatty Acids: The Role of Mitochondrial Metabolism.
Dos Reis Araujo T; Santiago D; Simões P; Guimarães F; Zoppi CC; Carneiro EM

Grants

Genomic plasticity and metabolic memory of skeletal muscle insulin resistance
Wenner-Gren Foundation
15 March 2024

Employments

Affiliated to Research, Department of Physiology and Pharmacology, Karolinska Institutet, 2024-2025

Degrees and Education

PhD, Functional and Molecular Biology, Functional and molecular characterization of the role of the Nr2f6 nuclear receptor in skeletal muscle, Structural and Functional Biology, State University of Campinas, 2023
Master, Biochemistry, Caracterização bioquímica e celular da proteína TRIM49, Biochemistry, Universidade de São Paulo, 2017

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