David Brodin

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Public outreach and news

Articles

Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1328401

Cystatin from the helminth Ascaris lumbricoides upregulates mevalonate and cholesterol biosynthesis pathways and immunomodulatory genes in human monocyte-derived dendritic cells.

Acevedo N; Lozano A; Zakzuk J; Llinás-Caballero K; Brodin D; Nejsum P; Williams AR; Caraballo L
Article: NATURE NEUROSCIENCE. 2023;26(6):1008-1020

ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain.

Stratoulias V; Ruiz R; Kanatani S; Osman AM; Keane L; Armengol JA; Rodríguez-Moreno A; Murgoci A-N; García-Domínguez I; Alonso-Bellido I; González Ibáñez F; Picard K; Vázquez-Cabrera G; Posada-Pérez M; Vernoux N; Tejera D; Grabert K; Cheray M; González-Rodríguez P; Pérez-Villegas EM; Martínez-Gallego I; Lastra-Romero A; Brodin D; Avila-Cariño J; Cao Y; Airavaara M; Uhlén P; Heneka MT; Tremblay M-È; Blomgren K; Venero JL; Joseph B
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2023;53(3):e2250083

Staphylococcus aureus-derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation.

Badolati I; van der Heiden M; Brodin D; Zuurveld M; Szilágyi S; Björkander S; Sverremark-Ekström E
Article: BIOMEDICINES. 2023;11(2):295

Intravenous Infusion of High Dose Selenite in End-Stage Cancer Patients: Analysis of Systemic Exposure to Selenite and Seleno-Metabolites.

Breuer O; Brodin O; Razaghi A; Brodin D; Gammelgaard B; Björnstedt M
Article: ANTICANCER RESEARCH. 2022;42(6):2827-2833

Altered mRNA Expression Due to Rectal Perforation in a Porcine Model - A Pilot Study.

Oikonomakis I; Brodin D; Hörer TM; Skoog P; Seilitz J; Nilsson KF; Meehan AD; Jansson K
Article: BMC GENOMICS. 2020;21(1):769

DNA methylation in infants with low and high body fatness.

Henriksson P; Lentini A; Altmäe S; Brodin D; Müller P; Forsum E; Nestor CE; Löf M
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(11):2272-2280.e12

Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins.

Sola-Carvajal A; Revêchon G; Helgadottir HT; Whisenant D; Hagblom R; Döhla J; Katajisto P; Brodin D; Fagerström-Billai F; Viceconte N; Eriksson M
Article: SCIENTIFIC REPORTS. 2018;8(1):15841

Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis.

Järver P; Dondalska A; Poux C; Sandberg A; Bergenstråhle J; Sköld AE; Dereuddre-Bosquet N; Martinon F; Pålsson S; Zaghloul E; Brodin D; Sander B; Lennox KA; Behlke MA; El-Andaloussi S; Lehtiö J; Lundeberg J; LeGrand R; Spetz A-L
Article: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. 2018;12(2):e720-e726

Study on genetic stability in human urothelial cells in vitro.

Chamorro CI; Zeiai S; Reinfeldt Engberg G; Brodin D; Lundin J; Nordenskjöld A; Fossum M
Journal article: BMJ GLOBAL HEALTH. 2017;2(Suppl 2):a17-A18

EFFECT OF ARTESUNATE MONOTHERAPY ON PLASMODIUM FALCIPARUM IN VIVO GENOMIC EXPRESSION

Kone A; Dara A; Niangaly A; Sinha I; Brodin D; Fofana B; Dama S; Dembele D; Sidibe B; Diallo N; Thera M; Sagara I; Wright K; Björkman A; Gil J; Doumbo O; Djimde A
Article: ONCOTARGET. 2017;8(3):4530-4542

Ameloblastoma RNA profiling uncovers a distinct non-coding RNA signature.

Davanian H; Balasiddaiah A; Heymann R; Sundström M; Redenström P; Silfverberg M; Brodin D; Sällberg M; Lindskog S; Kruger Weiner C; Chen M
Article: MOLECULAR BIOLOGY REPORTS. 2016;43(3):141-150

The transcriptional coregulator MAML1 affects DNA methylation and gene expression patterns in human embryonic kidney cells.

Putnik M; Brodin D; Wojdacz TK; Fagerström-Billai F; Dahlman-Wright K; Wallberg AE
Article: DIABETES. 2016;65(2):433-437

Numerous Genes in Loci Associated With Body Fat Distribution Are Linked to Adipose Function.

Dahlman I; Rydén M; Brodin D; Grallert H; Strawbridge RJ; Arner P
Article: ONCOIMMUNOLOGY. 2016;5(12):e1232222

Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.

Eissler N; Mao Y; Brodin D; Reuterswärd P; Andersson Svahn H; Johnsen JI; Kiessling R; Kogner P
Article: INTERNATIONAL JOURNAL OF OBESITY. 2015;39(6):910-919

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman I; Sinha I; Gao H; Brodin D; Thorell A; Rydén M; Andersson DP; Henriksson J; Perfilyev A; Ling C; Dahlman-Wright K; Arner P
Article: TISSUE ENGINEERING PART A. 2015;21(3-4):510-517

A study on proliferation and gene expression in normal human urothelial cells in culture.

Chamorro CI; Zeiai S; Engberg GR; Brodin D; Nordenskjöld A; Fossum M
Article: BONE MARROW TRANSPLANTATION. 2013;48(2):284-293

Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?

Sadeghi B; Al-Chaqmaqchi H; Al-Hashmi S; Brodin D; Hassan Z; Abedi-Valugerdi M; Moshfegh A; Hassan M
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(7):1593-1605

Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression.

Selenius M; Hedman M; Brodin D; Gandin V; Rigobello MP; Flygare J; Marzano C; Bindoli A; Brodin O; Björnstedt M; Fernandes AP
Article: BMC MOLECULAR BIOLOGY. 2011;12:46

SWI/SNF regulates the alternative processing of a specific subset of pre-mRNAs in Drosophila melanogaster.

Waldholm J; Wang Z; Brodin D; Tyagi A; Yu S; Theopold U; Farrants AKÖ; Visa N
Article: BMC MEDICAL GENOMICS. 2011;4:51

Genome wide association study identifies KCNMA1 contributing to human obesity.

Jiao H; Arner P; Hoffstedt J; Brodin D; Dubern B; Czernichow S; van't Hooft F; Axelsson T; Pedersen O; Hansen T; Sørensen TIA; Hebebrand J; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2011;41(2):281-287

Altered mRNA expression due to acute mesenteric ischaemia in a porcine model.

Block T; Isaksson HS; Acosta S; Björck M; Brodin D; Nilsson TK
Article: PLOS ONE. 2011;6(6):e14816

Specific syndecan-1 domains regulate mesenchymal tumor cell adhesion, motility and migration.

Zong F; Fthenou E; Mundt F; Szatmári T; Kovalszky I; Szilák L; Brodin D; Tzanakakis G; Hjerpe A; Dobra K
Article: JOURNAL OF INTERNAL MEDICINE. 2010;268(2):181-193

The role of IL-1beta in reduced IL-7 production by stromal and epithelial cells: a model for impaired T-cell numbers in the gut during HIV-1 infection.

Thang PH; Ruffin N; Brodin D; Rethi B; Cam PD; Hien NT; Lopalco L; Vivar N; Chiodi F
Article: BRITISH JOURNAL OF CANCER. 2010;102(10):1541-1548

Adipose tissue pathways involved in weight loss of cancer cachexia.

Dahlman I; Mejhert N; Linder K; Agustsson T; Mutch DM; Kulyte A; Isaksson B; Permert J; Petrovic N; Nedergaard J; Sjölin E; Brodin D; Clement K; Dahlman-Wright K; Rydén M; Arner P
Article: BMC GENOMICS. 2010;11:200

Genome-wide characterisation of the Gcn5 histone acetyltransferase in budding yeast during stress adaptation reveals evolutionarily conserved and diverged roles.

Xue-Franzén Y; Johnsson A; Brodin D; Henriksson J; Bürglin TR; Wright APH
Article: PLOS GENETICS. 2009;5(5):e1000470

SWI/SNF associates with nascent pre-mRNPs and regulates alternative pre-mRNA processing.

Tyagi A; Ryme J; Brodin D; Ostlund Farrants AK; Visa N
Article: EXPERIMENTAL CELL RESEARCH. 2007;313(14):3141-3152

Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines.

Dohda T; Maljukova A; Liu L; Heyman M; Grandér D; Brodin D; Sangfelt O; Lendahl U
Article: DIABETES. 2007;56(4):1095-1106

Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta-cell sensitivity.

Ma Z; Portwood N; Brodin D; Grill V; Björklund A
Article: DISEASES OF THE ESOPHAGUS. 2006;19(1):20-23

Genes associated with telomerase activity levels in esophageal carcinoma cell lines.

Bergqvist M; Brattström D; Brodin D; Lindkvist A; Dahlman-Wright K; Dreilich M; Wagenius G; Paulsson-Karlsson Y
Article: EXPERIMENTAL ONCOLOGY. 2005;27(2):102-107

Radiation-induced DNA-damage and gene expression profiles in human lung cancer cells with different radiosensitivity.

Hellman B; Brodin D; Andersson M; Dahlman-Wright K; Isacsson U; Brattstrom D; Bergqvist M
Article: JOURNAL OF CELL BIOLOGY. 2005;168(7):1013-1025

Hrp59, an hnRNP M protein in Chironomus and Drosophila, binds to exonic splicing enhancers and is required for expression of a subset of mRNAs.

Kiesler E; Hase ME; Brodin D; Visa N
Journal article: LUNG CANCER. 2003;41:s25

O-77 Genes associated with response to irradiation according to array studies

Lenneby C; Brodin D; Hedman M; Brattström D; Bergqvist M; Wagenius G; Dahlman-Wright K; Brodin O
Journal article: LUNG CANCER. 2003;41:s128

P-150 RNA-expression in radioresponsive and radioresistant human lungcancer cell-lines

Brodin OP; Hedman M; Brodin D; Bergqvist M; Brattström D; Wagenius G; Lenneby C; Dahlman-Wright K
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Letter: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2022;33(1):e13682

Transcriptome changes during peanut oral immunotherapy and omalizumab treatment.

Björkander S; Merid SK; Brodin D; Brandström J; Fagerström-Billai F; van der Heiden M; Konradsen JR; Kabesch M; van Drunen CM; Golebski K; Maitland-van der Zee AH; Potočnik U; Vijverberg SJH; Nopp A; Nilsson C; Melén E

Employments

Bioinformatician, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
Bioinformatician, Department of Biosciences and Nutrition, Karolinska Institutet, 2021-2024

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