Charlotte Höybye

Publications
CV
Public outreach and news

Articles

Article: ENDOCRINE CONNECTIONS. 2024;13(6):e240046
Venous thromboembolism in Cushing syndrome: results from an EuRRECa and Endo-ERN survey
Cherenko M; Appelman-Dijkstra NM; Zurita ALP; Biermasz NR; Dekkers OM; Klok FA; Reisch N; Aulinas A; Biagetti B; Cannavo S; Canu L; Detomas M; Devuyst F; Falhammar H; Feelders RA; Ferrau F; Gatto F; Grasselli C; van Houten P; Hoybye C; Isidori AM; Kyrilli A; Loli P; Maiter D; Nowak E; Pivonello R; Ragnarsson O; Steenaard RV; Unger N; van de Ven A; Webb SM; Yeste D; Ahmed SF; Pereira AM
Article: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. 2024;47(4):995-1003
Establishing a valid cohort of patients with acromegaly by combining the National Patient Register with the Swedish Pituitary Register
Robert J; Tsatsaris E; Berinder K; Bonelli L; Burman P; Dahlqvist P; Hoybye C; Olsson DS; Ragnarsson O; Vouzouneraki K; Akerman A-K; Ekman B; Engstrom BE
Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2023;37(6):101788
Comparing treatment with daily and long-acting growth hormone formulations in adults with growth hormone deficiency: Challenging issues, benefits, and risks
Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2023;108(12):e1506-e1514
Long-term Follow-up of 84 Patients With Giant Prolactinomas-A Swedish Nationwide Study
Himonakos C; Burman P; Borg H; Dahlqvist P; Engstroem BE; Ekman B; Emilsson L; Olsson DS; Ragnarsson O; Wahlberg J; Akerman A-K; Hoybye C; Berinder K
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2023;189(4):438-447
Altered biomarkers for cardiovascular disease and inflammation in autoimmune Addison's disease - a cross-sectional study
Saevik AB; Ueland G; Akerman A-K; Methlie P; Quinkler M; Jorgensen AP; Hoybye C; Debowska AWJ; Nedrebo BG; Dahle AL; Carlsen S; Tomkowicz A; Sollid ST; Nermoen I; Gronning K; Dahlqvist P; Grimnes G; Skov J; Finnes T; Valland SF; Wahlberg J; Holte SE; Kampe O; Bensing S; Husebye ES; Oksnes M
Article: CLINICAL CHEMISTRY AND LABORATORY MEDICINE. 2023;61(10):1780-1791
Salivary cortisol and cortisone in diagnosis of Cushing's syndrome - a comparison of six different analytical methods
Backlund N; Brattsand G; Lundstedt S; Aardal E; Bartuseviciene I; Berinder K; Hoybye C; Burman P; Eden Engstrom B; Isaksson A; Blomgren A; Ragnarsson O; Ruetschi U; Wahlberg J; Olsson T; Dahlqvist P
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2023;189(2):217-224
Pituitary function before and after surgery for nonfunctioning pituitary adenomas-data from the Swedish Pituitary Register
Al-Shamkhi N; Berinder K; Borg H; Burman P; Dahlqvist P; Hoybye C; Olsson DS; Ragnarsson O; Ekman B; Engstrom BE
Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(10):3602
Plasma-Metanephrines in Patients with Autoimmune Addison's Disease with and without Residual Adrenocortical Function
Akerman A-K; Saevik AB; Thorsby PM; Methlie P; Quinkler M; Jorgensen AP; Hoybye C; Debowska AJ; Nedrebo BG; Dahle AL; Carlsen S; Tomkowicz A; Sollid ST; Nermoen I; Gronning K; Dahlqvist P; Grimnes G; Skov J; Finnes T; Wahlberg J; Holte SE; Simunkova K; Kampe O; Husebye ES; Oksnes M; Bensing S
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2023;7(6):bvad054
Long-term Effectiveness and Safety of GH Replacement Therapy in Adults ≥60 Years: Data From NordiNet® IOS and ANSWER
Biller BMK; Hoybye C; Ferran J-M; Kelepouris N; Nedjatian N; Olsen AH; Weber MM; Gordon MB
Article: ENDOCRINE CONNECTIONS. 2023;12(1):e220267
Reduced CV risk with long-term GH replacement in AGHD: data from two large observational studies
Hoybye C; Biller BMK; Ferran J-M; Gordon MB; Kelepouris N; Nedjatian N; Olsen AH; Weber MM
Article: FRONTIERS IN MEDICINE. 2023;10:1172565
Register-based and genetic studies of Prader-Willi syndrome show a high frequency of gonadal tumors and a possible mechanism for tumorigenesis through imprinting relaxation
Maya-Gonzalez C; Wessman S; Lagerstedt-Robinson K; Taylan F; Tesi B; Kuchinskaya E; McCluggage WG; Poluha A; Holm S; Nergardh R; De Stahl TD; Hoybye C; Tettamanti G; Delgado-Vega AM; Skarin Nordenvall A; Nordgren A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2022;108(1):59-84
Bone Health in Adults With Prader-Willi Syndrome: Clinical Recommendations Based on a Multicenter Cohort Study
van Abswoude DH; Pellikaan K; Rosenberg AGW; Davidse K; Coupaye M; Hoybye C; Markovic TP; Grugni G; Crino A; Caixas A; Poitou C; Mosbah H; Weir T; van Vlimmeren LA; Rutges JPHJ; De Klerk LWL; Zillikens C; van der Lely AJ; de Graaff LCG
Article: JOURNAL OF CLINICAL MEDICINE. 2022;11(19):5510
Copeptin in Growth Hormone-Treated Patients
Sjostrom A; Chisalita SI; Hoybye C
Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2022;6(6):bvac045
Increased Mortality Persists after Treatment of Cushing's Disease: A Matched Nationwide Cohort Study
Bengtsson D; Ragnarsson O; Berinder K; Dahlqvist P; Engstrom BE; Ekman B; Hoybye C; Jaras J; Valdemarsson S; Burman P; Wahlberg J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2022;107(6):1698-1705
Approach to the Patient With Prader-Willi Syndrome
Hoybye C; Tauber M
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2022;186(3):329-339
Long-term outcomes of patients with acromegaly: a report from the Swedish Pituitary Register
Arnardottir S; Jaras J; Burman P; Berinder K; Dahlqvist P; Erfurth EM; Hoybye C; Larsson K; Ragnarsson O; Ekman B; Engstrom BE
Article: CLINICAL ENDOCRINOLOGY. 2022;96(1):54-61
Natural history and surgical outcome of Rathke's cleft cysts-A study from the Swedish Pituitary Registry
Petersson M; Berinder K; Engstrom BE; Tsatsaris E; Ekman B; Wahlberg J; Burman P; Borg H; Siesjo P; Dahlqvist P; Akerman A-K; Ragnarsson O; Olsson M; Forander P; Bensing S; Hoybye C
Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(24):5781
Hypogonadism in Women with Prader-Willi Syndrome-Clinical Recommendations Based on a Dutch Cohort Study, Review of the Literature and an International Expert Panel Discussion
Pellikaan K; Ben Brahim Y; Rosenberg AGW; Davidse K; Poitou C; Coupaye M; Goldstone AP; Hoybye C; Markovic TP; Grugni G; Crino A; Caixas A; Eldar-Geva T; Hirsch HJ; Gross-Tsur V; Butler MG; Miller JL; van der Kuy P-HM; van den Berg SAA; Visser JA; van der Lely AJ; de Graaff LCG
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(9):e3634-e3643
Effects of Growth Hormone Treatment on Sleep-Related Parameters in Adults With Prader-Willi Syndrome
Shukur HH; Hussain-Alkhateeb L; Farholt S; Norregaard O; Jorgensen AP; Hoybye C
Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(16):3613
Hyperprolactinemia in Adults with Prader-Willi Syndrome
Sjostrom A; Pellikaan K; Sjostrom H; Goldstone AP; Grugni G; Crino A; De Graaff LCG; Hoybye C
Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(16):3555
Hyponatremia in Children and Adults with Prader-Willi Syndrome: A Survey Involving Seven Countries
Coupaye M; Pellikaan K; Goldstone AP; Crino A; Grugni G; Markovic TP; Hoybye C; Caixas A; Mosbah H; De Graaff LCG; Tauber M; Poitou C
Article: PITUITARY. 2021;24(4):622-629
Safety and effectiveness of replacement with biosimilar growth hormone in adults with growth hormone deficiency: results from an international, post-marketing surveillance study (PATRO Adults)
Hoybye C; Beck-Peccoz P; Murray RD; Simsek S; Stalla G; Strasburger CJ; Urosevic D; Zouater H; Johannsson G
Article: PITUITARY. 2021;24(4):611-621
Pregnancy outcomes in women receiving growth hormone replacement therapy enrolled in the NordiNet® International Outcome Study (IOS) and the American Norditropin® Studies: Web-Enabled Research (ANSWER) Program
Biller BMK; Hoybye C; Carroll P; Gordon MB; Birkegard AC; Kelepouris N; Nedjatian N; Weber MM
Article: ENDOCRINE CONNECTIONS. 2021;10(7):805-814
Electrolyte and acid-base imbalance in severe COVID-19
Sjostrom A; Rysz S; Sjostrom H; Hoybye C
Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(12):2667
Twenty Years of GH Treatment in Adults with Prader-Willi Syndrome
Sjostrom A; Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(6):1750-1760
Psychotropic Drugs in Patients with Cushing's Disease Before Diagnosis and at Long-Term Follow-Up: A Nationwide Study
Bengtsson D; Ragnarsson O; Berinder K; Dahlqvist P; Engstrom BE; Ekman B; Hoybye C; Burman P; Wahlberg J
Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(9):1991
An Adapted Model for Transition to Adult Care in Young Adults with Prader-Willi Syndrome
Pedersen M; Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(4):1183-1194
Corticotroph Aggressive Pituitary Tumors and Carcinomas Frequently Harbor ATRX Mutations
Casar-Borota O; Boldt HB; Engstrom BE; Andersen MS; Baussart B; Bengtsson D; Berinder K; Ekman B; Feldt-Rasmussen U; Hoybye C; Jorgensen JOL; Kolnes AJ; Korbonits M; Rasmussen AK; Lindsay JR; Loughrey PB; Maiter D; Manojlovic-Gacic E; Pahnke J; Poliani PL; Popovic V; Ragnarsson O; Schalin-Jantti C; Scheie D; Toth M; Villa C; Wirenfeldt M; Kunicki J; Burman P
Article: HORMONE RESEARCH IN PAEDIATRICS. 2021;94(3-4):133-143
Safety and Effectiveness of Recombinant Human Growth Hormone in Children with Turner Syndrome: Data from the PATRO Children Study
Backeljauw P; Kanumakala S; Loche S; Schwab KO; Pfaffle RW; Hoybye C; Lundberg E; Battelino T; Kristrom B; Giemza T; Zouater H
Article: FRONTIERS IN ENDOCRINOLOGY. 2021;12:656950
Pituitary Apoplexy: A Retrospective Study of 33 Cases From a Single Center
Falhammar H; Tornvall S; Hoybye C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2021;184(1):123-131
Simplified and improved fluid deprivation test for diagnosing diabetes insipidus
Sjoestrom A; Bartuseviciene I; Hoybye C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2020;:EJE-20-1180.R1-332
ESE audit on management of Adult Growth Hormone Deficiency in clinical practice.
Martel-Duguech LM; Jorgensen JOL; Korbonits M; Johannsson G; Webb SM; Amadidou F; Mintziori G; Arosio M; Giavoli C; Badiu C; Boschetti M; Ferone D; Ricci Bitti S; Brue T; Albarel F; Cannavò S; Cotta OR; Carvalho D; Salazar D; Christ E; Debono M; Dusek T; Garcia-Centeno R; Ghigo E; Gasco V; Góth MI; Oláh D; Kovacs L; Höybye C; Kocjan T; Mlekuš Kozamernik K; Kužma M; Payer J; Medic-Stojanoska M; Novak A; Miličević T; Pekic S; Miljic D; Perez Luis J; Pico AM; Preda V; Raverot G; Borson-Chazot F; Rochira V; Monzani ML; Sandahl K; Tsagarakis S; Mitravela V; Zacharieva S; Zilaitiene B; Verkauskiene R
Article: BMC ENDOCRINE DISORDERS. 2020;20(1):166
Hair cortisol-a method to detect chronic cortisol levels in patients with Prader-Willi syndrome
Shukur HH; de Rijke YB; van Rossum EFC; Hussain-Alkhateeb L; Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(8):dgaa291-2624
Excess Morbidity Persists in Patients With Cushing's Disease During Long-term Remission: A Swedish Nationwide Study
Papakokkinou E; Olsson DS; Chantzichristos D; Dahlqvist P; Segerstedt E; Olsson T; Petersson M; Berinder K; Bensing S; Hoybye C; Eden-Engstrom B; Burman P; Bonelli L; Follin C; Petranek D; Erfurth EM; Wahlberg J; Ekman B; Akerman A-K; Schwarcz E; Bryngelsson I-L; Johannsson G; Ragnarsson O
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(7):dgaa256-2441
Residual Corticosteroid Production in Autoimmune Addison Disease
Saevik AB; Akerman A-K; Methlie P; Quinkler M; Jorgensen AP; Hoybye C; Debowska AJ; Nedrebo BG; Dahle AL; Carlsen S; Tomkowicz A; Sollid ST; Nermoen I; Gronning K; Dahlqvist P; Grimnes G; Skov J; Finnes T; Valland SF; Wahlberg J; Holte SE; Simunkova K; Kampe O; Husebye ES; Bensing S; Oksnes M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2020;105(7):dgaa168-e2571
Central Adrenal Insufficiency Is Rare in Adults With Prader-Willi Syndrome
Rosenberg AGW; Pellikaan K; Poitou C; Goldstone AP; Hoybye C; Markovic T; Grugni G; Crino A; Caixas A; Coupaye M; Van den Berg SAA; Van der Lely AJ; De Graaff LCG
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2020;182(6):569-582
Reference intervals of salivary cortisol and cortisone and their diagnostic accuracy in Cushing's syndrome
Backlund N; Brattsand G; Israelsson M; Ragnarsson O; Burman P; Engstrom BE; Hoybye C; Berinder K; Wahlberg J; Olsson T; Dahlqvist P
Article: BMC ENDOCRINE DISORDERS. 2020;20(1):55
Ten years with biosimilar rhGH in clinical practice in Sweden - experience from the prospective PATRO children and adult studies
Lundberg E; Kristrom B; Zouater H; Deleskog A; Hoybye C
Article: GROWTH HORMONE AND IGF RESEARCH. 2020;50:71-82
Growth hormone replacement in adults: Real-world data from two large studies in US and Europe
Weber MM; Gordon MB; Hoeybye C; Jorgensen JOL; Puras G; Popovic-Brkic V; Molitch ME; Ostrow V; Holot N; Pietropoli A; Biller BMK
Article: THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM. 2020;11:2042018820943377
Malignancy risk in adults with growth hormone deficiency undergoing long-term treatment with biosimilar somatropin (Omnitrope(R)): data from the PATRO Adults study
Beck-Peccoz P; Hoybye C; Murray RD; Simsek S; Zabransky M; Zouater H; Stalla G
Article: BMC ENDOCRINE DISORDERS. 2019;19(1):138
No increased risk of glucose metabolism disorders in adults with growth hormone deficiency undergoing long-term treatment with biosimilar somatropin (Omnitrope®): data from an observational, longitudinal study
Beck-Peccoz P; Hoybye C; Murray RD; Simsek S; Zabransky M; Zouater H; Stalla G
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2019;181(6):629-638
Change in baseline characteristics over 20 years of adults with growth hormone (GH) deficiency on GH replacement therapy
Hoybye C; Burman P; Feldt-Rasmussen U; Hey-Hadavi J; Aydin F; Camacho-Hubner C; Mattsson AF
Article: ACTA NEUROCHIRURGICA. 2019;161(8):1715-1721
Evaluation of different hydrocortisone treatment strategies in transsphenoidal pituitary surgery
Fridman-Bengtsson O; Hoybye C; Porthen L; Stjarne P; Hulting A-L; Sunnergren O
Article: ENDOCRINE CONNECTIONS. 2019;8(6):772-779
Serum soluble urokinase plasminogen activator receptor (suPAR) in adults with growth hormone deficiency
Hoybye C; Faseh L; Himonakos C; Pielak T; Eugen-Olsen J
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2019;104(6):2375-2384
Overall and Disease-Specific Mortality in Patients With Cushing Disease: A Swedish Nationwide Study
Ragnarsson O; Olsson DS; Papakokkinou E; Chantzichristos D; Dahlqvist P; Segerstedt E; Olsson T; Petersson M; Berinder K; Bensing S; Hoybye C; Eden-Engstrom B; Burman P; Bonelli L; Follin C; Petranek D; Erfurth EM; Wahlberg J; Ekman B; Akerman A-K; Schwarcz E; Bryngelsson I-L; Johannsson G
Article: PITUITARY. 2019;22(2):179-186
The incidence of Cushing's disease: a nationwide Swedish study
Ragnarsson O; Olsson DS; Chantzichristos D; Papakokkinou E; Dahlqvist P; Segerstedt E; Olsson T; Petersson M; Berinder K; Bensing S; Hoybye C; Engstrom BE; Burman P; Bonelli L; Follin C; Petranek D; Erfurth EM; Wahlberg J; Ekman B; Akerman A-K; Schwarcz E; Bryngelsson I-L; Johannsson G
Article: JOURNAL OF REHABILITATION MEDICINE. 2019;51(4):264-272
IMPACT OF PITUITARY DYSFUNCTION ON COGNITIVE AND GLOBAL OUTCOME AFTER TRAUMATIC BRAIN INJURY AND ANEURYSMAL SUBARACHNOID HAEMORRHAGE
Tolli A; Hoybye C; Bellander B-M; Borg J
Article: ENDOCRINE. 2018;62(2):456-463
Temporal relationship of sleep apnea and acromegaly: a nationwide study
Vouzouneraki K; Franklin KA; Forsgren M; Warn M; Persson JT; Wik H; Dahlgren C; Nilsson A-S; Alkebro C; Burman P; Erfurth E-M; Wahlberg J; Akerman A-K; Hoybye C; Ragnarsson O; Engstrom BE; Dahlqvist P
Article: BRAIN INJURY. 2018;32(12):1465-1476
The effect of time on cognitive impairments after non-traumatic subarachnoid haemorrhage and after traumatic brain injury
Tolli A; Hoybye C; Bellander B-M; Johansson F; Borg J
Article: JOURNAL OF INTERNAL MEDICINE. 2018;283(2):190-199
Clues for early detection of autoimmune Addison's disease - myths and realities
Saevik AB; Akerman A-K; Gronning K; Nermoen I; Valland SF; Finnes TE; Isaksson M; Dahlqvist P; Bergthorsdottir R; Ekwall O; Skov J; Nedrebo BG; Hulting A-L; Wahlberg J; Svartberg J; Hoybye C; Bleskestad IH; Jorgensen AP; Kampe O; Oksnes M; Bensing S; Husebye ES
Article: CLINICAL ENDOCRINOLOGY. 2017;86(6):798-805
Is GH dosing optimal in female patients with adult-onset GH deficiency? An analysis from the NordiNet® International Outcome Study
Hoybye C; Weber MM; Pournara E; Pedersen BT; Biller BMK
Article: ENDOCRINE CONNECTIONS. 2017;6(3):129-138
A phase 2 trial of long-acting TransCon growth hormone in adult GH deficiency
Hoybye C; Pfeiffer AFH; Ferone D; Christiansen JS; Gilfoyle D; Christoffersen ED; Mortensen E; Leff JA; Beckert M
Article: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. 2017;40(2):193-205
Pituitary function within the first year after traumatic brain injury or subarachnoid haemorrhage
Tolli A; Borg J; Bellander B-M; Johansson F; Hoybye C
Article: CLINICAL ENDOCRINOLOGY. 2017;86(2):192-198
The effect of growth hormone (GH) replacement on blood glucose homeostasis in adult nondiabetic patients with GH deficiency: real-life data from the NordiNet^® International Outcome Study
Weber MM; Biller BMK; Pedersen BT; Pournara E; Christiansen JS; Hoybye C
Article: ENDOCRINE. 2017;55(1):296-302
Frequency of Cushing's syndrome due to ACTH-secreting adrenal medullary lesions: a retrospective study over 10 years from a single center
Falhammar H; Calissendorff J; Hoybye C
Article: ARCHIVES OF GYNECOLOGY AND OBSTETRICS. 2016;294(2):267-271
Circulating maternal cortisol levels during vaginal delivery and elective cesarean section
Stjernholm YV; Nyberg A; Cardell M; Hoybye C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2016;174(6):C1-C8
Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations
Christiansen JS; Backeljauw PF; Bidlingmaier M; Biller BMK; Boguszewski MCS; Casanueva FF; Chanson P; Chatelain P; Choong CS; Clemmons DR; Cohen LE; Cohen P; Frystyk J; Grimberg A; Hasegawa Y; Haymond MW; Ho K; Hoffman AR; Holly JMP; Horikawa R; Hoeybye C; Jorgensen JOL; Johannsson G; Juul A; Katznelson L; Kopchick JJ; Lee KO; Lee K-W; Luo X; Melmed S; Miller BS; Misra M; Popovic V; Rosenfeld RG; Ross J; Ross RJ; Saenger P; Strasburger CJ; Thorner MO; Werner H; Yuen K
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2016;101(3):988-998
Reversible Albumin-Binding GH Possesses a Potential Once-Weekly Treatment Profile in Adult Growth Hormone Deficiency
Rasmussen MH; Janukonyte J; Klose M; Marina D; Tanvig M; Nielsen LF; Hoybye C; Andersen M; Feldt-Rasmussen U; Christiansen JS
Article: PLOS ONE. 2016;11(2):e0148802
Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in Humans
Lehtihet M; Bonde Y; Beckman L; Berinder K; Hoybye C; Rudling M; Sloan JH; Konrad RJ; Angelin B
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2015;100(4):1689-1698
Long-Term Outcome and MGMT as a Predictive Marker in 24 Patients With Atypical Pituitary Adenomas and Pituitary Carcinomas Given Treatment With Temozolomide
Bengtsson D; Schroder HD; Andersen M; Maiter D; Berinder K; Rasmussen UF; Rasmussen AK; Johannsson G; Hoybye C; van der Lely AJ; Petersson M; Ragnarsson O; Burman P
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2015;104(4):422-427
Growth hormone treatment of Prader-Willi syndrome has long-term, positive effects on body composition
Hoybye C
Article: BEST PRACTICE AND RESEARCH: CLINICAL ENDOCRINOLOGY AND METABOLISM. 2015;29(1):115-123
Growth hormone replacement in adults - current standards and new perspectives
Hoybye C; Christiansen JS
Article: ENDOCRINE CONNECTIONS. 2014;3(4):200-206
Metabolomics: a tool for the diagnosis of GH deficiency and for monitoring GH replacement?
Hoybye C; Wahlstrom E; Tollet-Egnell P; Norstedt G
Article: GROWTH HORMONE AND IGF RESEARCH. 2014;24(1):16-21
Glucose homeostasis in adults with Prader-Willi syndrome during treatment with growth hormone: Results from a 12-month prospective study
Jorgensen AP; Ueland T; Sode-Carlsen R; Schreiner T; Rabben KF; Farholt S; Hoybye C; Christiansen JS; Bollerslev J
Article: EXPERT REVIEW OF ENDOCRINOLOGY AND METABOLISM. 2013;8(6):529-536
Current status of growth hormone therapy in Prader-Willi syndrome.
Höybye C
Article: JOURNAL OF INTERNAL MEDICINE. 2013;274(3):227-232
Influence of growth hormone on circulating fibroblast growth factor 21 levels in humans
Lundberg J; Hoybye C; Krusenstjerna-Hafstrom T; Bina HA; Kharitonenkov A; Angelin B; Rudling M
Article: PSYCHONEUROENDOCRINOLOGY. 2013;38(6):842-852
Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy
Holmer H; Svensson J; Rylander L; Johannsson G; Rosen T; Bengtsson B-A; Thoren M; Hoybye C; Degerblad M; Bramnert M; Hagg E; Engstrom BE; Ekman B; Erfurth E-M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2013;98(6):E1072-E1087
Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome
Deal CL; Tony M; Hoybye C; Allen DB; Tauber M; Christiansen JS
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2013;98(4):1466-1475
Deaths Among Adult Patients With Hypopituitarism: Hypocortisolism During Acute Stress, and De Novo Malignant Brain Tumors Contribute to an Increased Mortality
Burman P; Mattsson AF; Johannsson G; Hoybye C; Holmer H; Dahlqvist P; Berinder K; Engstrom BE; Ekman B; Erfurth EM; Svensson J; Wahlberg J; Karlsson FA
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2013;98(4):E753-E760
Two Years of Growth Hormone Treatment in Adults With Prader-Willi Syndrome Do Not Improve the Low BMD
Jorgensen AP; Ueland T; Sode-Carlsen R; Schreiner T; Rabben KF; Farholt S; Hoybye C; Christiansen JS; Bollerslev J
Article: ISRN ENDOCRINOLOGY. 2013;2013:148497-9
Improved Insulin Sensitivity during Pioglitazone Treatment Is Associated with Changes in IGF-I and Cortisol Secretion in Type 2 Diabetes and Impaired Glucose Tolerance.
Arnetz L; Rajamand Ekberg N; Höybye C; Brismar K; Alvarsson M
Article: CLINICAL EPIDEMIOLOGY. 2013;5:119-127
The NordiNet® International Outcome Study and NovoNet® ANSWER Program®: rationale, design, and methodology of two international pharmacoepidemiological registry-based studies monitoring long-term clinical and safety outcomes of growth hormone therapy (Norditropin®).
Höybye C; Sävendahl L; Christesen HT; Lee P; Pedersen BT; Schlumpf M; Germak J; Ross J
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2012;167(5):697-703
Effects on insulin sensitivity and body composition of combination therapy with GH and IGF1 in GH deficient adults with type 2 diabetes
Barner C; Petersson M; Engstrom BE; Hoybye C
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2012;166(4):593-600
Comorbidity and cardiovascular risk factors in adult GH deficiency following treatment for Cushing's disease or non-functioning pituitary adenomas during childhood
Ragnarsson O; Hoybye C; Jonsson PJ; Feldt-Rasmussen U; Johannsson G; Biller BMK; Koltowska-Haggstrom M
Article: PITUITARY. 2011;14(3):199-207
Insulin sensitivity and lipid profile in prolactinoma patients before and after normalization of prolactin by dopamine agonist therapy
Berinder K; Nystrom T; Hoybye C; Hall K; Hulting A-L
Article: GROWTH HORMONE AND IGF RESEARCH. 2011;21(4):185-190
Growth hormone treatment for two years is safe and effective in adults with Prader-Willi syndrome
Sode-Carlsen R; Farholt S; Rabben KF; Bollerslev J; Schreiner T; Junk AG; Frystyk J; Christiansen JS; Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2011;96(1):E173-E180
Normal Cortisol Response to High-Dose Synacthen and Insulin Tolerance Test in Children and Adults with Prader-Willi Syndrome
Farholt S; Sode-Carlsen R; Christiansen JS; Ostergaard JR; Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2010;95(11):4943-4950
One Year of Growth Hormone Treatment in Adults with Prader-Willi Syndrome Improves Body Composition: Results from a Randomized, Placebo-Controlled Study
Sode-Carlsen R; Farholt S; Rabben KF; Bollerslev J; Schreiner T; Jurik AG; Christiansen JS; Hoybye C
Article: GROWTH HORMONE AND IGF RESEARCH. 2010;20(3):179-184
Body composition, endocrine and metabolic profiles in adults with Prader-Willi syndrome
Sode-Carlsen R; Farholt S; Rabben KF; Bollerslev J; Schreiner T; Jurik AG; Christiansen JS; Hoybye C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2010;95(6):2646-2654
Discontinuation of Growth Hormone (GH) Treatment during the Transition Phase Is an Important Factor Determining the Phenotype of Young Adults with Nonidiopathic Childhood-Onset GH Deficiency
Koltowska-Haggstrom M; Geffner ME; Jonsson P; Monson JP; Abs R; Hana V; Hoybye C; Wollmann HA
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2010;162(4):677-684
Clinical features of GH deficiency and effects of 3 years of GH replacement in adults with controlled Cushing's disease
Hoybye C; Ragnarsson O; Jonsson PJ; Koltowska-Haggstrom M; Trainer P; Feldt-Rasmussen U; Biller BMK
Article: GROWTH HORMONE AND IGF RESEARCH. 2009;19(3):206-211
Amino acid profiles in adults with growth hormone (GH) deficiency before and during GH replacement therapy
Fernholm R; Thoren M; Hoybye C; Anderstam B; Pernow Y; Saaf M; Hall K
Article: PITUITARY. 2009;12(3):211-216
Adjuvant Gamma Knife radiosurgery in non-functioning pituitary adenomas; low risk of long-term complications in selected patients
Hoybye C; Rahn T
Article: DISABILITY AND REHABILITATION. 2009;31(21):1780-1784
Assessment of physical function in adults with Prader-Willi syndrome
Sode-Carlsen R; Farholt S; Rabben EF; Bollerslev J; Christiansen JS; Hoybye C
Article: HORMONE AND METABOLIC RESEARCH. 2008;40(7):498-501
Contribution of gluconeogenesis and glycogenolysis to hepatic glucose production in acromegaly before and after pituitary microsurgery
Hoybye C; Chandramouli V; Efendic S; Hulting A-L; Landau BR; Schumann WC; Wajngot A
Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2007;22(12):1842-1850
Fracture incidence in GH-deficient patients on complete hormone replacement including GH
Holmer H; Svensson J; Rylander L; Johannsson G; Rosen T; Bengtsson B-A; Thoren M; Hoybye C; Degerblad M; Bramnert M; Haegg E; Engstroem BE; Ekman B; Thorngren K-G; Hagmar L; Erfurth E-M
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2007;157(5):589-596
Impact of the primary aetiology upon the clinical outcome of adults with childhood-onset GH deficiency
Hoybye C; Joensson P; Monson JP; Koltowska-Haeggstroem M; Hana V; Geffner M; Abs R
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2007;92(9):3560-3567
Nonfatal stroke, cardiac disease, and diabetes mellitus in hypopituitary patients on hormone replacement including growth hormone
Holmer H; Svensson J; Rylander L; Johannsson G; Rosen T; Bengtsson B-A; Thoren M; Hoybye C; Degerblad M; Bramnert M; Hagg E; Engstrom BE; Ekman B; Norrving B; Hagmar L; Erfurth E-M
Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2007;96(3):410-413
Five-years growth hormone (GH) treatment in adults with Prader-Willi syndrome
Hoybye C
Article: ANNALS OF NUTRITION AND METABOLISM. 2007;51(3):264-269
Eating behavior and gastric emptying in adults with Prader-Willi syndrome
Hoybye C; Barkeling B; Naslund E; Thoren M; Hellstrom PM
Article: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. 2006;29(11):950-956
Long-term GH treatment of GH-deficient adults:: Comparison between one and two daily injections
Hoybye C; Rudling M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2006;91(9):3296-3302
Ghrelin stimulates gastric emptying and hunger in normal-weight humans
Levin F; Edholm T; Schmidt PT; Gryback P; Jacobsson H; Degerblad M; Hoybye C; Holst JJ; Rehfeld JF; Hellstrom PM; Naslund E
Article: HORMONE RESEARCH IN PAEDIATRICS. 2006;66(1):27-32
Inflammatory markers in adults with Prader-Willi syndrome before and during 12 months growth hormone treatment
Hoybye C
Article: GROWTH HORMONE AND IGF RESEARCH. 2005;15(6):411-415
Growth hormone induced lipolysis during short- and long-term administration in adult Prader-Willi patients
Höybye C; Hilding A; Marcus C; Thorén M
Article: JOURNAL OF INTELLECTUAL DISABILITY RESEARCH. 2005;49(Pt 4):245-252
Cognitive, emotional, physical and social effects of growth hormone treatment in adults with Prader-Willi syndrome
Höybye C; Thorén M; Böhm B
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2004;151(4):457-461
Serum adiponectin levels in adults with Prader-Willi syndrome are independent of anthropometrical parameters and do not change with GH treatment
Höybye C; Bruun JM; Richelsen B; Flyvbjerg A; Frystyk J
Article: JOURNAL OF NEUROSURGERY. 2004;100(4):634-638
Transsphenoidal surgery in Cushing disease:: 10 years of experience in 34 consecutive cases
Höybye C; Grenbäck E; Thorén M; Hulting AL; Lundblad L; Von Holst H; Änggård A
Article: GROWTH HORMONE AND IGF RESEARCH. 2003;13(6):322-327
Peptides associated with hyperphagia in adults with Prader-Willi syndrome before and during GH treatment
Höybye C; Barkeling B; Espelund U; Petersson M; Thorén M
Article: GROWTH HORMONE AND IGF RESEARCH. 2003;13(5):269-274
The growth hormone-insulin-like growth factor axis in adult patients with Prader Willi syndrome
Höybye C; Frystyk J; Thorén M
Article: CLINICAL ENDOCRINOLOGY. 2003;58(5):653-661
Growth hormone treatment improves body composition in adults with Prader-Willi syndrome
Höybye C; Hilding A; Jacobsson H; Thorén M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2002;87(8):3590-3597
Metabolic profile and body composition in adults with Prader-Willi syndrome and severe obesity
Höybye C; Hilding A; Jacobsson H; Thorén M
Article: JOURNAL OF NEURO-ONCOLOGY. 2001;54(2):197-203
The role of gamma knife radiosurgery in the management of pituitary adenomas
Thorén M; Höybye C; Grenbäck E; Degerblad M; Rähn T; Hulting AL
Article: NEUROSURGERY. 2001;49(2):284-291
Adrenocorticotropic hormone-producing pituitary tumors:: 12-to 22-year follow-up after treatment with stereotactic radiosurgery
Höybye C; Grenbäck E; Rähn T; Degerblad M; Thorén M; Hulting AL
Show more

All other publications

Corrigendum: FRONTIERS IN ENDOCRINOLOGY. 2024;15:1357219
Kidney disease in adults with Prader-Willi syndrome: international cohort study and systematic literature review (vol 11, 1168648, 2023)
van Abswoude DH; Pellikaan K; Nguyen N; Rosenberg AGW; Davidse K; Hoekstra FME; Rood IM; Poitou C; Grugni G; Hoybye C; Markovic TP; Caixas A; Crino A; van den Berg SAA; van der Lely AJ; de Graaff LCG
Review: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2023;108(12):e1720-e1730
Malignancies in Prader-Willi Syndrome: Results From a Large International Cohort and Literature Review
Pellikaan K; Nguyen NQC; Rosenberg AGW; Coupaye M; Goldstone AP; Hoybye C; Markovic T; Grugni G; Crino A; Caixas A; Poitou C; Corripio R; Nieuwenhuize RM; Van der Lely AJ; de Graaff LCG
Review: ENDOCRINE CONNECTIONS. 2023;12(1):e220373
The transition from pediatric to adult care in individuals with Prader-Willi syndrome
Poitou C; Holland A; Hoybye C; de Graaff LCG; Bottius S; Otterlei B; Tauber M
Review: FRONTIERS IN ENDOCRINOLOGY. 2023;14:1168648
Kidney disease in adults with Prader-Willi syndrome: international cohort study and systematic literature review
van Abswoude DH; Pellikaan K; Nguyen N; Rosenberg AGW; Davidse K; Hoekstra FME; Rood IM; Poitou C; Grugni G; Hoybye C; Markovic TP; Caixas A; Crino A; van den Berg SA; van der Lely AJ; de Graaff LCG
Review: PITUITARY. 2021;24(5):797-809
Prevalence of Nelson's syndrome after bilateral adrenalectomy in patients with cushing's disease: a systematic review and meta-analysis
Papakokkinou E; Piasecka M; Carlsen HK; Chantzichristos D; Olsson DS; Dahlqvist P; Petersson M; Berinder K; Bensing S; Hoybye C; Engstrom BE; Burman P; Follin C; Petranek D; Erfurth EM; Wahlberg J; Ekman B; Akerman A-K; Schwarcz E; Johannsson G; Falhammar H; Ragnarsson O
Review: JOURNAL OF CLINICAL MEDICINE. 2021;10(19):4361
Hypogonadism in Adult Males with Prader-Willi Syndrome-Clinical Recommendations Based on a Dutch Cohort Study, Review of the Literature and an International Expert Panel Discussion
Pellikaan K; Ben Brahim Y; Rosenberg AGW; Davidse K; Poitou C; Coupaye M; Goldstone AP; Hoybye C; Markovic TP; Grugni G; Crino A; Caixas A; Eldar-Geva T; Hirsch HJ; Gross-Tsur V; Butler MG; Miller JL; van den Berg SAA; van der Lely AJ; de Graaff LCG
Review: THE LANCET DIABETES AND ENDOCRINOLOGY. 2021;9(4):235-246
Endocrine disorders in Prader-Willi syndrome: a model to understand and treat hypothalamic dysfunction
Tauber M; Hoybye C
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(5):2705
Prader-Willi Syndrome and Hypogonadism: A Review Article
Noordam C; Hoybye C; Eiholzer U
Letter: ORPHANET JOURNAL OF RARE DISEASES. 2021;16(1):69
Time for a general approval of growth hormone treatment in adults with Prader-Willi syndrome
Hoeybye C; Holland AJ; Driscoll DJ
Review: EXPERT OPINION ON DRUG SAFETY. 2020;19(12):1539-1548
Safety of current recombinant human growth hormone treatments for adults with growth hormone deficiency and unmet needs
Hoybye C; Beck-Peccoz P; Simsek S; Zabransky M; Zouater H; Stalla G; Murray RD
Letter: CLINICAL ENDOCRINOLOGY. 2019;91(4):578-579
Letter regarding "Prevalence of growth hormone deficiency in previously GH-treated young adults with Prader-Willi syndrome" by Donze et al
Hoybye C; Tauber M; Angulo MA; Eiholzer U; Driscoll DJ; Cassidy SB; Holland AJ
Letter: ENDOCRINE. 2018;62(3):737-739
Tumoral MGMT content predicts survival in patients with aggressive pituitary tumors and pituitary carcinomas given treatment with temozolomide
Bengtsson D; Schroder HD; Berinder K; Maiter D; Hoybye C; Ragnarsson O; Feldt-Rasmussen U; Rasmussen AK; van der Lely A; Petersson M; Johannsson G; Andersen M; Burman P
Other: LAKARTIDNINGEN. 2018;115:E3DP
[
One steroid injection in combination with HIV-medication resulted in a total adrenal insufficiency
].
Rössner S; Höybye C
Review: ENDOCRINE CONNECTIONS. 2016;5(6):R44-R54
Bridging the gap: metabolic and endocrine care of patients during transition
Hokken-Koelega A; van der Lely A-J; Hauffa B; Haeusler G; Johannsson G; Maghnie M; Argente J; DeSchepper J; Gleeson H; Gregory JW; Hoybye C; Kelestimur F; Luger A; Mueller HL; Neggers S; Popovic-Brkic V; Porcu E; Savendahl L; Shalet S; Spiliotis B; Tauber M
Review: ENDOCRINE CONNECTIONS. 2016;5(5):R35-R43
Clinical aspects of symptomatic hyponatremia
Weismann D; Schneider A; Hoybye C
Review: GROWTH HORMONE AND IGF RESEARCH. 2015;25(5):201-206
Status of long-acting-growth hormone preparations-2015
Hoybye C; Cohen P; Hoffman AR; Ross R; Biller BMK; Christiansen JS
Review: CURRENT MEDICAL RESEARCH AND OPINION. 2014;30(7):1201-1207
Review and analysis of differing regulatory indications and expert panel guidelines for the treatment of hyponatremia
Verbalis JG; Grossman A; Hoybye C; Runkle I
Editorial comment: PAEDIATRIC DRUGS. 2013;15(6):427-429
Long-Acting Growth Hormone
Hoybye C; Christiansen JS
Review: ENDOCRINE. 2012;41(2):191-199
Growth hormone treatment in adults with Prader-Willi syndrome: the Scandinavian study
Sode-Carlsen R; Farholt S; Rabben KF; Bollerslev J; Schreiner T; Jurik AG; Christiansen JS; Hoybye C
Review: GROWTH HORMONE AND IGF RESEARCH. 2004;14(1):1-15
Endocrine and metabolic aspects of adult Prader-Willi syndrome with special emphasis on the effect of growth hormone treatment
Höybye C
Review: TREATMENTS IN ENDOCRINOLOGY. 2004;3(3):153-160
Somatropin therapy in adults with Prader-Willi syndrome.
Höybye C; Thorén M
Thesis / dissertation: 2003
Endocrine and metabolic aspects of adult Prader Willi syndrome with special emphasis on the effect of growth hormone treatment
Höybye, Charlotte
Show more

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Karolinska institutet, 2007
Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2003

Supervisor

Ann Sjöström, Severe COVID-19 and routine biomarker pattern, http://hdl.handle.net/10616/48787, 2019

Articles

All other publications

Employments

Degrees and Education

Supervisor

News from KI

Events from KI