Changrong Ge

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Article: ARTHRITIS & RHEUMATOLOGY. 2022;74(6):961-971
Antibodies to Cartilage Oligomeric Matrix Protein Are Pathogenic in Mice and May Be Clinically Relevant in Rheumatoid Arthritis
Ge C; Tong D; Loennblom E; Liang B; Cai W; Fahlquist-Hagert C; Li T; Kastbom A; Gjertsson I; Dobritzsch D; Holmdahl R
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(4):480-489
Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor
Ge C; Weisse S; Xu B; Dobritzsch D; Viljanen J; Kihlberg J; Do N-N; Schneider N; Lanig H; Holmdahl R; Burkhardt H
Article: SCIENCE ADVANCES. 2022;8(6):eabm1759
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation
Kissel T; Ge C; Hafkenscheid L; Kwekkeboom JC; Slot LM; Cavallari M; He Y; van Schie KA; Vergroesen RD; Kampstra ASB; Reijm S; Stoeken-Rijsbergen G; Koeleman C; Voortman LM; Heitman LH; Xu B; Pruijn GJM; Wuhrer M; Rispens T; Huizinga TWJ; Scherer HU; Reth M; Holmdahl R; Toes REM
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:631249
Cartilage Oligomeric Matrix Protein Induced Arthritis-A New Model for Rheumatoid Arthritis in the C57BL/6 Mouse
Zhao Y; Urbonaviciute V; Xu B; Cai W; Sener Z; Ge C; Holmdahl R
Article: ACS CHEMICAL BIOLOGY. 2020;15(9):2605-2615
Synthesis of an Array of Triple-Helical Peptides from Type II Collagen for Multiplex Analysis of Autoantibodies in Rheumatoid Arthritis
Viljanen J; Lonnblom E; Ge C; Yang J; Cheng L; Aldi S; Cai W; Kastbom A; Sjowall C; Gjertsson I; Holmdahl R; Kihlberg J
Article: RHEUMATOLOGY. 2019;58(9):1623-1633
The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis
Liang B; Ge C; Lonnblom E; Lin X; Feng H; Xiao L; Bai J; Ayoglu B; Nilsson P; Nandakumar KS; Zhao M; Holmdahl R
Article: NATURE REVIEWS RHEUMATOLOGY. 2019;15(8):503-508
The structure, specificity and function of anti-citrullinated protein antibodies
Ge C; Holmdahl R
Article: ARTHRITIS & RHEUMATOLOGY. 2019;71(2):210-221
Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies
Ge C; Xu B; Liang B; Lonnblom E; Lundstrom SL; Zubarev RA; Ayoglu B; Nilsson P; Skogh T; Kastbom A; Malmstrom V; Klareskog L; Toes REM; Rispens T; Dobritzsch D; Holmdahl R
Article: JOURNAL OF IMMUNOLOGY. 2017;199(12):3937-3942
Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis
Yang M; Haase C; Viljanen J; Xu B; Ge C; Kihlberg J; Holmdahl R
Article: JCI INSIGHT. 2017;2(13):93688
Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage
Ge CP; Tong DR; Liang BT; Lonnblom ES; Schneider NK; Hagert CU; Viljanen JV; Ayoglu BR; Stawikowska RT; Nilsson PC; Fields GB; Skogh TA; Kastbom AR; Kihlberg JT; Burkhardt HT; Dobritzsch DC; Holmdahl RK
Article: NATURE IMMUNOLOGY. 2017;18(1):104-113
Regulation of autoantibody activity by the IL-23-T_H17 axis determines the onset of autoimmune disease
Pfeifle R; Rothe T; Ipseiz N; Scherer HU; Culemann S; Harre U; Ackermann JA; Seefried M; Kleyer A; Uderhardt S; Haugg B; Huebert AJ; Daum P; Heidkamp GF; Ge C; Boehm S; Lux A; Schuh W; Magorivskal I; Nandakumar KS; Loennblom E; Becker C; Dudziak D; Wuhrer M; Rombouts Y; Koeleman CA; Toes R; Winkler TH; Holmdahl R; Herrmann M; Blueml S; Nimmerjahn F; Schett G; Kroenke G
Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(5):1124-1135
A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis
Chemin K; Pollastro S; James E; Ge C; Albrecht I; Herrath J; Gerstner C; Tandre K; Rizzi TS; Ronnblom L; Catrina A; Holmdahl R; Klareskog L; de Vries N; Malmstrom V
Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2015;13(22):6203-6216
Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A^q/glycopeptide complexes
Lindgren C; Andersson IE; Berg L; Dobritzsch D; Ge C; Haag S; Uciechowska U; Holmdahl R; Kihlberg J; Linusson A
Article: FEBS JOURNAL. 2014;281(16):3667-3684
Membrane remodeling capacity of a vesicle-inducing glycosyltransferase
Ge C; Gomez-Llobregat J; Skwark MJ; Ruysschaert J-M; Wieslander A; Linden M
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2014;211(3):405-411
Epitope-specific antibody response is controlled by immunoglobulin V_H polymorphisms
Raposo B; Dobritzsch D; Ge C; Ekman D; Xu B; Lindh I; Forster M; Uysal H; Nandakumar KS; Schneider G; Holmdahl R
Article: MOLECULAR PLANT. 2014;7(1):121-136
Import determinants of organelle-specific and dual targeting peptides of mitochondria and chloroplasts in Arabidopsis thaliana.
Ge C; Spånning E; Glaser E; Wieslander A
Article: BIOCHEMISTRY. 2013;52(33):5533-5544
Anionic lipid binding to the foreign protein MGS provides a tight coupling between phospholipid synthesis and protein overexpression in Escherichia coli.
Ariöz C; Ye W; Bakali A; Ge C; Liebau J; Götzke H; Barth A; Wieslander A; Mäler L
Article: STRUCTURE. 2012;20(6):1062-1070
The Mycobacterium tuberculosis very-long-chain fatty acyl-CoA synthetase: structural basis for housing lipid substrates longer than the enzyme.
Andersson CS; Lundgren CAK; Magnúsdóttir A; Ge C; Wieslander A; Martinez Molina D; Högbom M
Article: JOURNAL OF PROTEOME RESEARCH. 2011;10(8):3617-3631
Model for membrane organization and protein sorting in the cyanobacterium Synechocystis sp. PCC 6803 inferred from proteomics and multivariate sequence analyses.
Pisareva T; Kwon J; Oh J; Kim S; Ge C; Wieslander A; Choi J-S; Norling B
Article: BIOCHEMISTRY. 2011;50(21):4451-4466
Lipid interacting regions in phosphate stress glycosyltransferase atDGD2 from Arabidopsis thaliana.
Szpryngiel S; Ge C; Iakovleva I; Georgiev A; Lind J; Wieslander A; Mäler L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(8):6669-6684
Tryptophan residues promote membrane association for a plant lipid glycosyltransferase involved in phosphate stress.
Ge C; Georgiev A; Öhman A; Wieslander Å; Kelly AA
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2009;284(49):33904-33914
Massive formation of intracellular membrane vesicles in Escherichia coli by a monotopic membrane-bound lipid glycosyltransferase.
Eriksson HM; Wessman P; Ge C; Edwards K; Wieslander A
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2006;101(7):1625-1632
Expression of polymeric immunoglobulin receptor mRNA and protein in human paneth cells: Paneth cells participate in acquired immunity.
Tang Q-J; Wang L-M; Tao K-Z; Ge C-R; Li J; Peng Y-L; Jiang C-L; Geng M-Y
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Corrigendum: ACS CHEMICAL BIOLOGY. 2020;15(11):3072
Synthesis of an Array of Triple-Helical Peptides from Type II Collagen for Multiplex Analysis of Autoantibodies in Rheumatoid Arthritis (vol 15, pg 2605, 2020)
Viljanen J; Lonnblom E; Ge C; Yang J; Cheng L; Aldi S; Cai W; Kastbom A; Sjowall C; Fields GB; Gjertsson I; Holmdahl R; Kihlberg J

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Affiliated to Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2025-2026
Research Specialist, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2024-2024

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