Carl Sellgren Majkowitz

About me
Publications
CV
Public outreach and news

About me

I am a Group leader and Associate Professor at the Department of Physiology and Pharmacology. I obtained my MD and PhD at the Karolinska Institutet and completed my residency in psychiatry at Psykiatri Nordväst (Stockholm County) in 2011. My postdoctoral training was performed at the Broad Institiute of MIT and Harvard.

Research

Neurodevelopment, developmental biology, neurodevelopmental disorder, psychiatry, disease modeling, glial biology.

Articles

Article: JAMA PSYCHIATRY. 2024;81(5):468-476
Cognitive Function and Variability in Antipsychotic Drug-Naive Patients With First-Episode Psychosis
Lee M; Cernvall M; Borg J; Plaven-Sigray P; Larsson C; Erhardt S; Sellgren CM; Fatouros-Bergman H; Cervenka S
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2024;117:313-319
Lower complement C1q levels in first-episode psychosis and in schizophrenia
Koskuvi M; Malwade S; Lekander JG; Horbeck E; Bruno S; Larsson JH; Pelanis A; Isgren A; Goulding A; Fatouros-Bergman H; Samudyata; Schalling M; Piehl F; Erhardt S; Landen M; Cervenka S; Orhan F; Sellgren CM
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2024;171:306-315
Cerebrospinal fluid proteomic signatures are associated with symptom severity of first-episode psychosis
Haroon H; Ho AM-C; Gupta VK; Dasari S; Sellgren CM; Cervenka S; Engberg G; Eren F; Erhardt S; Sung J; Choi D-S
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2024;116:150-159
Dissecting the impact of complement component 4A in bipolar disorder
Horbeck E; Jonsson L; Malwade S; Karlsson R; Palsson E; Sigstrom R; Sellgren CM; Landen M
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2023;77(12):665-671
Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis
Pils M; Rutsch J; Eren F; Engberg G; Piehl F; Cervenka S; Sellgren C; Trossbach S; Willbold D; Erhardt S; Bannach O; Korth C
Journal article: BIOMARKERS IN NEUROPSYCHIATRY. 2023;9:100078
Altered brain dopamine metabolism is a trait marker for bipolar disorder
Pålsson E; Sellgren C; Pelanis A; Zetterberg H; Blennow K; Landén M
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2023;111:376-385
Immunological protein profiling of first-episode psychosis patients identifies CSF and blood biomarkers correlating with disease severity
Eren F; Schwieler L; Orhan F; Malmqvist A; Piehl F; Cervenka S; Sellgren CM; Fatouros-Bergman H; Engberg G; Erhardt S
Article: SCHIZOPHRENIA RESEARCH. 2023;257:34-40
CSF dopamine is elevated in first-episode psychosis and associates to symptom severity and cognitive performance
Orhan F; Goiny M; Becklen M; Mathe L; Piehl F; Schwieler L; Fatouros-Bergman H; Farde L; Cervenka S; Sellgren CM; Engberg G; Erhardt S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14):e2213880120
Large- scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Schijven D; Postema MC; Fukunaga M; Matsumoto J; Miura K; de Zwarte SMC; van Haren NEM; Cahn W; Pol HEH; Kahn RS; Ayesa-Arriola R; de la Foz VO-G; Tordesillas-Gutierrez D; Vazquez-Bourgon J; Crespo-Facorro B; Alnaes D; Dahl A; Westlye LT; Agartz I; Andreassen OA; Jonsson EG; Kochunov P; Bruggemann JM; Catts SV; Michie PT; Mowry BJ; Quide Y; Rasser PE; Schall U; Scott RJ; Carr VJ; Green MJ; Henskens FA; Loughland CM; Pantelis C; Weickert CS; Weickert TW; De Haan L; Brosch K; Pfarr J-K; Ringwald KG; Stein F; Jansen A; Kircher TTJ; Nenadic I; Kramer B; Gruber O; Satterthwaite TD; Bustillo J; Mathalon DH; Preda A; Calhoun VD; Ford JM; Potkin SG; Chen J; Tan Y; Wang Z; Xiang H; Fan F; Bernardoni F; Ehrlich S; Fuentes-Claramonte P; Garcia-Leon MA; Guerrero-Pedraza A; Salvador R; Sarro S; Pomarol-Clotet E; Ciullo V; Piras F; Vecchio D; Banaj N; Spalletta G; Michielse S; van Amelsvoort T; Dickie EW; Voineskos AN; Sim K; Ciufolini S; Dazzan P; Murray RM; Kim W-S; Chung Y-C; Andreou C; Schmidt A; Borgwardt S; McIntosh AM; Whalley HC; Lawrie SM; Du Plessis S; Luckhoff HK; Scheffler F; Emsley R; Grotegerd D; Lencer R; Dannlowski U; Edmond JT; Rootes-Murdy K; Stephen JM; Mayer AR; Antonucci LA; Fazio L; Pergola G; Bertolino A; Diaz-Caneja CM; Janssen J; Lois NG; Arango C; Tomyshev AS; Lebedeva I; Cervenkav S; Sellgrenv CM; Georgiadis F; Kirschner M; Kaiser S; Hajek T; Skoch A; Spaniel F; Kim M; Bin Kwak Y; Oh S; Kwon JS; James A; Bakker G; Knochel C; Stablein M; Oertel V; Uhlmann A; Howells FM; Stein DJ; Temmingh HS; Diaz-Zuluaga AM; Pineda-Zapata JA; Lopez-Jaramillo C; Homan S; Ji E; Surbeck W; Homan P; Fishera SE; Franke B; Glahn DC; Gur RC; Hashimoto R; Jahanshad N; Luders E; Medland SE; Thompson PM; Turner JA; van Erp TGM; Francks C
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14)
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Schijven D; Postema MC; Fukunaga M; Matsumoto J; Miura K; de Zwarte SMC; van Haren NEM; Cahn W; Pol HEH; Kahn RS; Ayesa-Arriola R; de la Foz VO-G; Tordesillas-Gutierrez D; Vazquez-Bourgoni J; Crespo-Facorro B; Alnaes D; Dahl A; Westlye LT; Agartz I; Andreassen OA; Jonsson EG; Kochunov P; Bruggemann JM; Catts SV; Michie PT; Mowry BJ; Quide Y; Rasser PE; Schall U; Scott RJ; Carr VJ; Green MJ; Henskens FA; Loughland CM; Pantelis C; Weickert CS; Weickert TW; de Haan L; Brosch K; Pfarr J-K; Ringwald KG; Stein F; Jansen A; Kircher TTJ; Nenadic I; Kramer B; Gruber O; Satterthwaite TD; Bustillo J; Mathalon DH; Preda A; Calhoun VD; Ford JM; Potkin SG; Chen J; Tan Y; Wang Z; Xiang H; Fan F; Bernardoni F; Ehrlich S; Fuentes-Claramonte P; Garcia-Leon MA; Guerrero-Pedraza A; Salvador R; Sarro S; Pomarol-Clotet E; Ciullo V; Piras F; Vecchio D; Banaj N; Spalletta G; Michielse S; van Amelsvoort T; Dickie EW; Voineskos AN; Sim K; Ciufolini S; Dazzan P; Murray RM; Kim W-S; Chung Y-C; Andreou C; Schmidt A; Borgwardt S; McIntosh AM; Whalley HC; Lawrie SM; du Plessis S; Luckhoff HK; Scheffler F; Emsley R; Grotegerd D; Lencer R; Dannlowski U; Edmond JT; Rootes-Murdy K; Stephen JM; Mayer AR; Antonucci LA; Fazio L; Pergola G; Bertolino A; Diaz-Caneja CM; Janssen J; Lois NG; Arango C; Tomyshev AS; Lebedeva I; Cervenka S; Sellgren CM; Georgiadis F; Kirschner M; Kaiser S; Hajek T; Skoch A; Spaniel F; Kim M; Bin Kwak Y; Oh S; Kwon JS; James A; Bakker G; Knochel C; Stablein M; Oertel V; Uhlmann A; Howells FM; Stein DJ; Temmingh HS; Diaz-Zuluaga AM; Pineda-Zapata JA; Lopez-Jaramillo C; Homan S; Ji E; Surbeck W; Homan P; Fisher SE; Franke B; Glahn DC; Gur RC; Hashimoto R; Jahanshad N; Luders E; Medland SE; Thompson PM; Turner JA; van Erp TGM; Francks C
Journal article: NEUROSCIENCE APPLIED. 2023;2:103444
Comparative studies of microglia-like cells, in anorexia nervosa patients versus healthy controls
Xu J; Orhan F; Sellgren C; Nilsson I
Journal article: NEUROSCIENCE APPLIED. 2023;2:103319
Human 2D and 3D models of oligodendrocyte progenitor cell development and function
Gkogka A; Samudyata S; Malwade S; Koskuvi M; Sellgren C
Journal article: NEUROSCIENCE APPLIED. 2023;2:102643
Elevated synaptic pruning by microglia in schizophrenia across patient-derived brain organoids
Malwade S; Lekander JG; Samudyata S; Koskuvi M; Storvik M; Sellgren CM
Journal article: NEUROSCIENCE APPLIED. 2023;2:102623
Modelling human cytomegalovirus infection in immunocompetent brain organoids
Koskuvi M; Samudyata S; Malwade S; Almazán NM; Gkogka A; Söderberg-Nauclér C; Sellgren CM
Journal article: NEUROSCIENCE APPLIED. 2023;2:103649
Modeling lithium’s effect on neurogenesis using induced pluripotent stem cell-derived neural stem cells and brain organoids
Lundberg M; Koskuvi M; Samudyata S; Malwade S; Schalling M; Sellgren C
Journal article: NEUROSCIENCE APPLIED. 2023;2:101139
Functional connectivity alterations of the somatomotor network in euthymic bipolar disorder
Klahn AL; Thompson WH; Abé C; Liberg B; Sellgren CM; Klahn P; Landén M
Journal article: NEUROSCIENCE APPLIED. 2023;2:103551
Kynurenic acid promotes activity-dependent synaptic pruning and associates with genetic risk variance for schizophrenia
Orhan F; Malwade S; Schwieler L; Tiihonen J; Koistinahu J; Erhardt S; Engberg G; Kent J; Samudyata S; Sellgren C
Article: NATURE COMMUNICATIONS. 2022;13(1):6427
Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia
Gracias J; Orhan F; Horbeck E; Holmen-Larsson J; Khanlarkani N; Malwade S; Goparaju SK; Schwieler L; Demirel IS; Fu T; Fatourus-Bergman H; Pelanis A; Goold CP; Goulding A; Annerbrink K; Isgren A; Sparding T; Schalling M; Yanez VAC; Gopfert JC; Nilsson J; Brinkmalm A; Blennow K; Zetterberg H; Engberg G; Piehl F; Sheridan SD; Perlis RH; Cervenka S; Erhardt S; Landen M; Sellgren CM
Article: MOLECULAR PSYCHIATRY. 2022;27(11):4568-4574
Cerebrospinal fluid proteomic study of two bipolar disorder cohorts
Isgren A; Goteson A; Holmen-Larsson J; Pelanis A; Sellgren C; Joas E; Sparding T; Zetterberg H; Smedler E; Jakobsson J; Landen M
Article: MOLECULAR PSYCHIATRY. 2022;27(10):3939-3950
SARS-CoV-2 promotes microglial synapse elimination in human brain organoids
Samudyata; Oliveira AO; Malwade S; de Sousa NR; Goparaju SK; Gracias J; Orhan F; Steponaviciute L; Schalling M; Sheridan SD; Perlis RH; Rothfuchs AG; Sellgren CM
Article: HELIYON. 2022;8(9):e10424
Facial affect recognition in first-episode psychosis is impaired but not associated with psychotic symptoms
Larsson C; Lee M; Lundgren T; Erhardt S; Sellgren CM; Cervenka S; Borg J; Bolte S; Fatouros-Bergman H
Article: MOLECULAR PSYCHIATRY. 2022;27(8):3247-3261
Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia
Matlik K; Garton DR; Montano-Rodriguez AR; Olfat S; Eren F; Casserly L; Damdimopoulos A; Panhelainen A; Porokuokka LL; Kopra JJ; Turconi G; Schweizer N; Bereczki E; Piehl F; Engberg G; Cervenka S; Piepponen TP; Zhang F-P; Sipila P; Jakobsson J; Sellgren CM; Erhardt S; Andressoo J-O
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):229
Identification of cerebrospinal fluid and serum metabolomic biomarkers in first episode psychosis patients
Shang P; Ho AM-C; Tufvesson-Alm M; Lindberg DR; Grant CW; Orhan F; Eren F; Bhat M; Engberg G; Schwieler L; Fatouros-Bergman H; Imbeault S; Iverson RM; Dasari S; Piehl F; Cervenka S; Sellgren CM; Erhardt S; Choi D-S
Article: MOLECULAR PSYCHIATRY. 2022;27(2):1233-1240
Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis
Plaven-Sigray P; Ikonen Victorsson P; Santillo A; Matheson GJ; Lee M; Collste K; Fatouros-Bergman H; Sellgren CM; Erhardt S; Agartz I; Halldin C; Farde L; Cervenka S
Article: BRAIN AND BEHAVIOR. 2022;12(1):e2472
Serum concentration of zinc is elevated in clinically stable bipolar disorder patients
Jonsson BH; Orhan F; Bruno S; Oliveira AO; Sparding T; Landen M; Sellgren CM
Article: HUMAN BRAIN MAPPING. 2022;43(1):352-372
A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium
Gutman BA; van Erp TGM; Alpert K; Ching CRK; Isaev D; Ragothaman A; Jahanshad N; Saremi A; Zavaliangos-Petropulu A; Glahn DC; Shen L; Cong S; Alnaes D; Andreassen OA; Nhat TD; Westlye LT; Kochunov P; Satterthwaite TD; Wolf DH; Huang AJ; Kessler C; Weideman A; Nguyen D; Mueller BA; Faziola L; Potkin SG; Preda A; Mathalon DH; Bustillo J; Calhoun V; Ford JM; Walton E; Ehrlich S; Ducci G; Banaj N; Piras F; Piras F; Spalletta G; Canales-Rodriguez EJ; Fuentes-Claramonte P; Pomarol-Clotet E; Radua J; Salvador R; Sarro S; Dickie EW; Voineskos A; Tordesillas-Gutierrez D; Crespo-Facorro B; Setien-Suero E; van Son JM; Borgwardt S; Schoenborn-Harrisberger F; Morris D; Donohoe G; Holleran L; Cannon D; McDonald C; Corvin A; Gill M; Busatto Filho G; Rosa PGP; Serpa MH; Zanetti MV; Lebedeva I; Kaleda V; Tomyshev A; Crow T; James A; Cervenka S; Sellgren CM; Fatouros-Bergman H; Agartz I; Howells F; Stein DJ; Temmingh H; Uhlmann A; de ZGI; McMahon KL; Wright M; Cobia D; Csernansky JG; Thompson PM; Turner JA; Wang L
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):566
Screening for pathogenic neuronal autoantibodies in serum and CSF of patients with first-episode psychosis
Theorell J; Ramberger M; Harrison R; Mgbachi V; Jacobson L; Waters P; Erhardt S; Sellgren CM; Cervenka S; Piehl F; Irani SR
Article: MOLECULAR PSYCHIATRY. 2021;26(11):6820-6832
GRK3 deficiency elicits brain immune activation and psychosis
Sellgren CM; Imbeault S; Larsson MK; Oliveros A; Nilsson IAK; Codeluppi S; Orhan F; Bhat M; Tufvesson-Alm M; Gracias J; Kegel ME; Zheng Y; Faka A; Svedberg M; Powell SB; Caldwell S; Kamenski ME; Vawter MP; Schullman A; Goiny M; Svensson CI; Hokfelt T; Schalling M; Schwieler L; Cervenka S; Choi D-S; Landen M; Engberg G; Erhardt S
Article: NPJ SCHIZOPHRENIA. 2021;7(1):46
No association between cortical dopamine D2 receptor availability and cognition in antipsychotic-naive first-episode psychosis
Lee M; Fatouros-Bergman H; Plaven-Sigray P; Victorsson PI; Sellgren CM; Erhardt S; Flyckt L; Farde L; Cervenka S
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2021;46(4):E441-E450
Genetic risk for bipolar disorder and schizophrenia predicts structure and function of the ventromedial prefrontal cortex
Abe C; Petrovic P; Ossler W; Thompson WH; Liberg B; Song J; Bergen SE; Sellgren CM; Fransson P; Ingvar M; Landen M
Article: BJPSYCH OPEN. 2021;7(4):e115
Long-term trajectory of cognitive performance in people with bipolar disorder and controls: 6-year longitudinal study
Sparding T; Joas E; Clements C; Sellgren CM; Palsson E; Landen M
Article: SCIENTIFIC REPORTS. 2021;11(1):7527
Plasma bilirubin levels are reduced in first-episode psychosis patients and associates to working memory and duration of untreated psychosis
Becklen M; Orhan F; Piehl F; Cervenka S; Sellgren CM; Flyckt L; Erhardt S; Fatouros-Bergman H
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):179
Umbilical cord blood-derived microglia-like cells to model COVID-19 exposure
Sheridan SD; Thanos JM; De Guzman RM; McCrea LT; Horng JE; Fu T; Sellgren CM; Perlis RH; Edlow AG
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;43:52-62
Central levels of tryptophan metabolites in subjects with bipolar disorder
Trepci A; Sellgren CM; Palsson E; Brundin L; Khanlarkhani N; Schwieler L; Landen M; Erhardt S
Article: BIOLOGICAL PSYCHIATRY: COGNITIVE NEUROSCIENCE AND NEUROIMAGING. 2020;5(12):1095-1103
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study
Tonnesen S; Kaufmann T; de Lange A-MG; Richard G; Nhat TD; Alnaes D; van der Meer D; Rokicki J; Moberget T; Maximov II; Agartz I; Aminoff SR; Beck D; Barch DM; Beresniewicz J; Cervenka S; Fatouros-Bergman H; Craven AR; Flyckt L; Gurholt TP; Haukvik UK; Hugdahl K; Johnsen E; Jonsson EG; Kolskar KK; Kroken RA; Lagerberg TV; Loberg E-M; Nordvik JE; Sanders A-M; Ulrichsen K; Andreassen OA; Westlye LT
Article: NATURE COMMUNICATIONS. 2020;11(1):4016
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Elvsashagen T; Bahrami S; van der Meer D; Agartz I; Alnaes D; Barch DM; Baur-Streubel R; Bertolino A; Beyer MK; Blasi G; Borgwardt S; Boye B; Buitelaar J; Boen E; Celius EG; Cervenka S; Conzelmann A; Coynel D; Di Carlo P; Djurovic S; Eisenacher S; Espeseth T; Fatouros-Bergman H; Flyckt L; Franke B; Frei O; Gelao B; Harbo HF; Hartman CA; Haberg A; Heslenfeld D; Hoekstra PJ; Hogestol EA; Jonassen R; Jonsson EG; Kirsch P; Kloszewska I; Lagerberg TV; Landro NI; Le Hellard S; Lesch K-P; Maglanoc LA; Malt UF; Mecocci P; Melle I; Meyer-Lindenberg A; Moberget T; Nordvik JE; Nyberg L; O'Connell KS; Oosterlaan J; Papalino M; Papassotiropoulos A; Pauli P; Pergola G; Persson K; de Quervain D; Reif A; Rokicki J; van Rooij D; Shadrin AA; Schmidt A; Schwarz E; Selbaek G; Soininen H; Sowa P; Steen VM; Tsolaki M; Vellas B; Wang L; Westman E; Ziegler GC; Zink M; Andreassen OA; Westlye LT; Kaufmann T; Farde L; Flyckt L; Engberg G; Erhardt SS; Fatouros-Bergman H; Cervenka S; Schwieler L; Piehl F; Agartz I; Collste K; Victorsson P; Malmqvist A; Hedberg M; Orhan F; Sellgren CM
Article: IBRO REPORTS. 2020;8:136-142
CSF levels of synaptosomal-associated protein 25 and synaptotagmin-1 in first-episode psychosis subjects
Xu C; Sellgren CM; Fatouros-Bergman H; Piehl F; Blennow K; Zetterberg H; Brinkmalm A; Santillo AF; Lundgren S; Cervenka S; Engberg G; Erhardt S
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2020;141(6):534-540
Reporting trigger factors for (hypo)manic episodes in bipolar disorder: association with personality and prognosis
Smedler E; Sparding T; Hattab A; Sellgren CM; Landen M
Article: NEUROPSYCHOPHARMACOLOGY. 2020;45(4):656-665
Exosomal secretion of a psychosis-altered miRNA that regulates glutamate receptor expression is affected by antipsychotics
Amoah SK; Rodriguez BA; Logothetis CN; Chander P; Sellgren CM; Weick JP; Sheridan SD; Jantzie LL; Webster MJ; Mellios N
Article: TRANSLATIONAL PSYCHIATRY. 2020;10(1):58
Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls
Zhang R; Song J; Isgren A; Jakobsson J; Blennow K; Sellgren CM; Zetterberg H; Bergen SE; Landen M
Article: BIOLOGICAL PSYCHIATRY. 2020;87(3):271-281
Longitudinal Cortical Thickness Changes in Bipolar Disorder and the Relationship to Genetic Risk, Mania, and Lithium Use
Abe C; Liberg B; Song J; Bergen SE; Petrovic P; Ekman CJ; Sellgren CM; Ingvar M; Landen M
Article: JAMA PSYCHIATRY. 2019;76(7):739-748
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
Alnaes D; Kaufmann T; van der Meer D; Cordova-Palomera A; Rokicki J; Moberget T; Bettella F; Agartz I; Barch DM; Bertolino A; Brandt CL; Cervenka S; Djurovic S; Nhat TD; Eisenacher S; Fatouros-Bergman H; Flyckt L; Di Giorgio A; Haatveit B; Jonsson EG; Kirsch P; Lund MJ; Meyer-Lindenberg A; Pergola G; Schwarz E; Smeland OB; Quarto T; Zink M; Andreassen OA; Westlye LT; Farde L; Collste K; Victorsson P; Engberg G; Erhardt S; Malmqvist A; Hedberg M; Orhan F; Sellgren CM; Schwieler L; Piehl F
Article: NATURE NEUROSCIENCE. 2019;22(3):374-385
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
Sellgren CM; Gracias J; Watmuff B; Biag JD; Thanos JM; Whittredge PB; Fu T; Worringer K; Brown HE; Wang J; Kaykas A; Karmacharya R; Goold CP; Sheridan SD; Perlis RH
Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):37
Peripheral and central levels of kynurenic acid in bipolar disorder subjects and healthy controls
Sellgren CM; Gracias J; Jungholm O; Perlis RH; Engberg G; Schwieler L; Landen M; Erhardt S
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2018;138(5):432-440
Increased number of monocytes and plasma levels of MCP-1 and YKL-40 in first-episode psychosis
Orhan F; Schwieler L; Fatouros-Bergman H; Malmqvist A; Cervenka S; Collste K; Flyckt L; Farde L; Sellgren CM; Piehl F; Engberg G; Erhardt S
Article: MOLECULAR PSYCHIATRY. 2018;23(5):1244-1250
CSF GABA is reduced in first-episode psychosis and associates to symptom severity
Orhan F; Fatouros-Bergman H; Goiny M; Malmqvist A; Piehl F; Cervenka S; Collste K; Victorsson P; Sellgren CM; Flyckt L; Erhardt S; Engberg G
Article: PSYCHIATRY RESEARCH. 2017;258:9-14
Prevalences of autoimmune diseases in schizophrenia, bipolar I and II disorder, and controls
Cremaschi L; Kardell M; Johansson V; Isgren A; Sellgren CM; Altamura AC; Hultman CM; Landen M
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2017;65:195-201
Markers of neuroinflammation and neuronal injury in bipolar disorder: Relation to prospective clinical outcomes
Isgren A; Sellgren C; Ekman C-J; Holmen-Larsson J; Blennow K; Zetterberg H; Jakobsson J; Landen M
Article: COGNITIVE NEUROPSYCHIATRY. 2017;22(5):407-421
Classification of cognitive performance in bipolar disorder
Sparding T; Silander K; Palsson E; Ostlind J; Ekman CJ; Sellgren CM; Joas E; Hansen S; Landen M
Article: JOURNAL OF NEURAL TRANSMISSION. 2017;124(9):1135-1143
Cerebrospinal fluid monoamine metabolite profiles in bipolar disorder, ADHD, and controls
Palsson E; Sellgren C; Ryden E; Kizza R; Pelanis A; Zetterberg H; Blennow K; Landen M
Article: MALARIA JOURNAL. 2017;16(1):303
Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria
Holmberg D; Franzen-Rohl E; Idro R; Opoka RO; Bangirana P; Sellgren CM; Wickstrom R; Farnert A; Schwieler L; Engberg G; John CC
Article: PSYCHOLOGICAL MEDICINE. 2017;47(6):1107-1115
Prevalence of current anxiety disorders in people with bipolar disorder during euthymia: a meta-analysis.
Pavlova B; Perlis RH; Mantere O; Sellgren CM; Isometsä E; Mitchell PB; Alda M; Uher R
Article: MOLECULAR PSYCHIATRY. 2017;22(2):170-177
Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors
Sellgren CM; Sheridan SD; Gracias J; Xuan D; Fu T; Perlis RH
Article: SCHIZOPHRENIA BULLETIN. 2017;43(1):99-107
A History of Psychosis in Bipolar Disorder is Associated With Gray Matter Volume Reduction
Ekman CJ; Petrovic P; Johansson AGM; Sellgren C; Ingvar M; Landen M
Article: MOLECULAR PSYCHIATRY. 2016;21(11):1504-1510
Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis
Yoshimi N; Futamura T; Bergen SE; Iwayama Y; Ishima T; Sellgren C; Ekman CJ; Jakobsson J; Palsson E; Kakumoto K; Ohgi Y; Yoshikawa T; Landen M; Hashimoto K
Article: MOLECULAR PSYCHIATRY. 2016;21(10):1342-1350
A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder
Sellgren CM; Kegel ME; Bergen SE; Ekman CJ; Olsson S; Larsson M; Vawter MP; Backlund L; Sullivan PF; Sklar P; Smoller JW; Magnusson PKE; Hultman CM; Walther-Jallow L; Svensson CI; Lichtenstein P; Schalling M; Engberg G; Erhardt S; Landen M
Article: TRANSLATIONAL PSYCHIATRY. 2016;6(8):e865
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
Brundin L; Sellgren CM; Lim CK; Grit J; Palsson E; Landen M; Samuelsson M; Lundgren K; Brundin P; Fuchs D; Postolache TT; Traskman-Bendz L; Guillemin GJ; Erhardt S
Article: SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE. 2016;11(7):1041-1049
Significant grey matter changes in a region of the orbitofrontal cortex in healthy participants predicts emotional dysregulation
Petrovic P; Ekman CJ; Klahr J; Tigerstrom L; Ryden G; Johansson AGM; Sellgren C; Golkar A; Olsson A; Ohman A; Ingvar M; Landen M
Article: BBA CLINICAL. 2016;5:151-158
Blood metabolomics analysis identifies abnormalities in the citric acid cycle, urea cycle, and amino acid metabolism in bipolar disorder.
Yoshimi N; Futamura T; Kakumoto K; Salehi AM; Sellgren CM; Holmén-Larsson J; Jakobsson J; Pålsson E; Landén M; Hashimoto K
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2016;41(4):240-250
Cortical thickness, volume and surface area in patients with bipolar disorder types I and II
Abe C; Ekman C-J; Sellgren C; Petrovic P; Ingvar M; Landen M
Article: COGNITIVE NEUROPSYCHIATRY. 2016;21(3):271-278
Polymorphisms of BDNF and CACNA1C are not associated with cognitive functioning in bipolar disorder or healthy controls
Rolstad S; Majkowitz CS; Joas E; Ekman CJ; Palsson E; Landen M
Article: JOURNAL OF NEUROINFLAMMATION. 2016;13(1):51
Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients
Schwieler L; Samuelsson M; Frye MA; Bhat M; Schuppe-Koistinen I; Jungholm O; Johansson AG; Landen M; Sellgren CM; Erhardt S
Article: THE BRITISH JOURNAL OF PSYCHIATRY. SUPPLEMENT. 2016;208(2):195-196
CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder
Jakobsson J; Palsson E; Sellgren C; Rydberg F; Ekman A; Zetterberg H; Blennow K; Lander M
Article: BIPOLAR DISORDERS. 2015;17(8):859-868
Polymorphisms of dopamine pathway genes NRG1 and LMX1A are associated with cognitive performance in bipolar disorder
Rolstad S; Palsson E; Ekman CJ; Eriksson E; Sellgren C; Landen M
Article: BRAIN. 2015;138(Pt 11):3440-3448
Manic episodes are related to changes in frontal cortex: a longitudinal neuroimaging study of bipolar disorder 1
Abe C; Ekman C-J; Sellgren C; Petrovic P; Ingvar M; Landen M
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(8):1091-1098
CSF neuroinflammatory biomarkers in bipolar disorder are associated with cognitive impairment
Rolstad S; Jakobsson J; Sellgren C; Isgren A; Ekman CJ; Bjerke M; Blennow K; Zetterberg H; Palsson E; Landen M
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2015;40(4):250-258
Monocyte and microglial activation in patients with mood-stabilized bipolar disorder
Jakobsson J; Bjerke M; Sahebi S; Isgren A; Ekman CJ; Sellgren C; Olsson B; Zetterberg H; Blennow K; Palsson E; Landen M
Article: BRAIN IMAGING AND BEHAVIOR. 2015;9(2):333-341
Subcortical morphometry and psychomotor function in euthymic bipolar disorder with a history of psychosis
Liberg B; Ekman CJ; Sellgren C; Johansson AG; Landen M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2015;131(4):269-278
Low IL-8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels
Janelidze S; Suchankova P; Ekman A; Erhardt S; Sellgren C; Samuelsson M; Westrin A; Minthon L; Hansson O; Traskman-Bendz L; Brundin L
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2015;40(2):126-133
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia - significance for activation of the kynurenine pathway
Schwieler L; Larsson MK; Skogh E; Kegel ME; Orhan F; Abdelmoaty S; Finn A; Bhat M; Samuelsson M; Lundberg K; Dahl M-L; Sellgren C; Schuppe-Koistinen I; Svensson CI; Erhardt S; Engberg G
Article: PLOS ONE. 2015;10(5):e0127100
Cognitive Performance and Cerebrospinal Fluid Biomarkers of Neurodegeneration: A Study of Patients with Bipolar Disorder and Healthy Controls
Rolstad S; Jakobsson J; Sellgren C; Ekman C-J; Blennow K; Zetterberg H; Palsson E; Landen M
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(1):133-140
Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls
Palsson E; Jakobsson J; Sodersten K; Fujita Y; Sellgren C; Ekman C-J; Agren H; Hashimoto K; Landen M
Article: PLOS ONE. 2015;10(1):e0115562
Cognitive Functioning in Clinically Stable Patients with Bipolar Disorder I and II
Sparding T; Silander K; Palsson E; Ostlind J; Sellgren C; Ekman CJ; Joas E; Hansen S; Landen M
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2015;43:198-204
Increased cerebrospinal fluid interleukin-8 in bipolar disorder patients associated with lithium and antipsychotic treatment
Isgren A; Jakobsson J; Palsson E; Ekman CJ; Johansson AGM; Sellgren C; Blennow K; Zetterberg H; Landen M
Article: SCHIZOPHRENIA BULLETIN. 2014;40(6):1552-1559
The association between schizophrenia and rheumatoid arthritis: a nationwide population-based Swedish study on intraindividual and familial risks.
Sellgren C; Frisell T; Lichtenstein P; Landèn M; Askling J
Article: NEUROPSYCHOPHARMACOLOGY. 2014;39(10):2349-2356
Elevated Concentrations of Neurofilament Light Chain in the Cerebrospinal Fluid of Bipolar Disorder Patients
Jakobsson J; Bjerke M; Ekman CJ; Sellgren C; Johansson AGM; Zetterberg H; Blennow K; Landen M
Article: PSYCHIATRY RESEARCH. 2014;217(3):143-146
Blood-cerebrospinal fluid barrier dysfunction in patients with bipolar disorder in relation to antipsychotic treatment
Zetterberg H; Jakobsson J; Redsater M; Andreasson U; Palsson E; Ekman CJ; Sellgren C; Johansson AGM; Blennow K; Landen M
Article: PSYCHIATRY RESEARCH. 2014;221(3):173-178
Vertex-based morphometry in euthymic bipolar disorder implicates striatal regions involved in psychomotor function
Liberg B; Ekman CJ; Sellgren C; Johansson A; Landen M
Article: MOLECULAR PSYCHIATRY. 2014;19(3):334-341
The KMO allele encoding Arg⁴⁵² is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression
Lavebratt C; Olsson S; Backlund L; Frisen L; Sellgren C; Priebe L; Nikamo P; Traskman-Bendz L; Cichon S; Vawter MP; Osby U; Engberg G; Landen M; Erhardt S; Schalling M
Article: INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH. 2014;7:15-22
Imbalanced kynurenine pathway in schizophrenia.
Kegel ME; Bhat M; Skogh E; Samuelsson M; Lundberg K; Dahl M-L; Sellgren C; Schwieler L; Engberg G; Schuppe-Koistinen I; Erhardt S
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2013;38(4):E21-E26
Decreased cerebrospinal fluid secretogranin II concentrations in severe forms of bipolar disorder
Jakobsson J; Stridsberg M; Zetterberg H; Blennow K; Ekman C-J; Johansson AGM; Sellgren C; Landen M
Journal article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2012;28(&NA;):e42
Working memory performance in bipolar disorder
Sellgren C; Engberg G; Erhardt S; Lichtenstein P; Landèn M
Journal article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2012;28(&NA;):e41-e42
The Kynurenine pathway and cognitive performance in Euthymic bipolar disorder
Sellgren C; Olsson S; Erhardt S; Engberg G; Lichtenstein P; Landèn M
Journal article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2012;28(&NA;):e25
Genome-wide study of CSF kynurenic acid in bipolar disorder implicates a molecular pathway underlying psychosis
Sellgren C; Kegel M; Ekman C; Olsson S; Svensson C; Hultman C; Lichtenstein P; Purcell S; Sullivan P; Sklar P; Engberg G; Erhardt S; Landèn M
Journal article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2012;28(&NA;):e4
Can routinely collected data be used for research on bipolar disorder? data from the St. Göran bipolar project
Landén M; Rydén E; Johansson A; Wetterberg L; Jakobsson J; Pålsson E; Ekman CJ; Sellgren C; Olsson S; Erhardt S; Båve U
Article: BIPOLAR DISORDERS. 2012;14(7):719-726
Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder
Olsson SK; Sellgren C; Engberg G; Landen M; Erhardt S
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2011;124(6):447-453
Validity of bipolar disorder hospital discharge diagnoses: file review and multiple register linkage in Sweden
Sellgren C; Landen M; Lichtenstein P; Hultman CM; Langstrom N
Article: DIGESTIVE AND LIVER DISEASE. 2011;43(8):616-622
Increased suicide risk in coeliac disease-A Swedish nationwide cohort study
Ludvigsson JF; Sellgren C; Runeson B; Langstrom N; Lichtenstein P
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All other publications

Preprint: BIORXIV. 2023;BIORXIV
Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization.
Ge R; Yu Y; Qi YX; Fan YV; Chen S; Gao C; Haas SS; Modabbernia A; New F; Agartz I; Asherson P; Ayesa-Arriola R; Banaj N; Banaschewski T; Baumeister S; Bertolino A; Boomsma DI; Borgwardt S; Bourque J; Brandeis D; Breier A; Brodaty H; Brouwer RM; Buckner R; Buitelaar JK; Cannon DM; Caseras X; Cervenka S; Conrod PJ; Crespo-Facorro B; Crivello F; Crone EA; de Haan L; de Zubicaray GI; Di Giorgio A; Erk S; Fisher SE; Franke B; Frodl T; Glahn DC; Grotegerd D; Gruber O; Gruner P; Gur RE; Gur RC; Harrison BJ; Hatton SN; Hickie I; Howells FM; Pol HEH; Huyser C; Jernigan TL; Jiang J; Joska JA; Kahn RS; Kalnin AJ; Kochan NA; Koops S; Kuntsi J; Lagopoulos J; Lazaro L; Lebedeva IS; Lochner C; Martin NG; Mazoyer B; McDonald BC; McDonald C; McMahon KL; Nakao T; Nyberg L; Piras F; Portella MJ; Qiu J; Roffman JL; Sachdev PS; Sanford N; Satterthwaite TD; Saykin AJ; Schumann G; Sellgren CM; Sim K; Smoller JW; Soares J; Sommer IE; Spalletta G; Stein DJ; Tamnes CK; Thomopolous SI; Tomyshev AS; Tordesillas-Gutiérrez D; Trollor JN; van 't Ent D; van den Heuvel OA; van Erp TG; van Haren NE; Vecchio D; Veltman DJ; Walter H; Wang Y; Weber B; Wei D; Wen W; Westlye LT; Wierenga LM; Williams SC; Wright MJ; Medland S; Wu M-J; Yu K; Jahanshad N; Thompson PM; Frangou S
Letter: BRAIN, BEHAVIOR, AND IMMUNITY. 2023;114:163-164
Preanalytic handling of clinical blood samples in assessing immunological proteins - Role of storage duration
Eren F; Schwieler L; Orhan F; Malmqvist A; Piehl F; Cervenka S; Sellgren CM; Fatouros-Bergman H; Engberg G; Erhardt S
Preprint: BIORXIV. 2023
Kynurenic acid promotes activity-dependent synaptic pruning in schizophrenia
Orhan F; Malwade S; Khanlarkhani N; Gkoga A; Jungholm O; Koskuvi M; Lehtonen Š; Schwieler L; Jardemark K; Tiihonen J; Koistinaho J; Erhardt S; Engberg G; Samudyata S; Sellgren C
Preprint: PSYARXIV. 2023
Functional connectivity alterations of the somatomotor network in euthymic bipolar disorder
Klahn AL; Thompson WH; Abe C; Liberg B; Sellgren CM; Klahn P; Landén M
Preprint: MEDRXIV. 2023
Disrupted-in-schizophrenia 1 (DISC1) protein aggregates in cerebrospinal fluid are elevated in first-episode psychosis patients
Pils M; Rutsch J; Eren F; Engberg G; Piehl F; Cervenka S; Sellgren C; Troßbach S; Willbold D; Erhardt S; Bannach O; Korth C
Review: MOLECULAR PSYCHIATRY. 2023;28(1):34-43
Neurodevelopmental disorders-high-resolution rethinking of disease modeling
Khodosevich K; Sellgren CM
Preprint: MEDRXIV. 2022
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Schijven D; Postema MC; Fukunaga M; Matsumoto J; Miura K; de Zwarte SMC; van Haren NEM; Cahn W; Pol HEH; Kahn RS; Ayesa-Arriola R; de la Foz VO-G; Tordesillas-Gutierrez D; Vázquez-Bourgon J; Crespo-Facorro B; Alnæs D; Dahl A; Westlye LT; Agartz I; Andreassen OA; Jönsson EG; Kochunov P; Bruggemann JM; Catts SV; Michie PT; Mowry BJ; Quidé Y; Rasser PE; Schall U; Scott RJ; Carr VJ; Green MJ; Henskens FA; Loughland CM; Pantelis C; Weickert CS; Weickert TW; de Haan L; Brosch K; Pfarr J-K; Ringwald KG; Stein F; Jansen A; Kircher TTJ; Nenadic I; Krämer B; Gruber O; Satterthwaite TD; Bustillo J; Mathalon DH; Preda A; Calhoun VD; Ford JM; Potkin SG; Chen J; Tan Y; Wang Z; Xiang H; Fan F; Bernardoni F; Ehrlich S; Fuentes-Claramonte P; Garcia-Leon MA; Guerrero-Pedraza A; Salvador R; Sarró S; Pomarol-Clotet E; Ciullo V; Piras F; Vecchio D; Banaj N; Spalletta G; Michielse S; van Amelsvoort T; Dickie EW; Voineskos AN; Sim K; Ciufolini S; Dazzan P; Murray RM; Kim W-S; Chung Y-C; Andreou C; Schmidt A; Borgwardt S; McIntosh AM; Whalley HC; Lawrie SM; du Plessis S; Luckhoff HK; Scheffler F; Emsley R; Grotegerd D; Lencer R; Dannlowski U; Edmond JT; Rootes-Murdy K; Stephen JM; Mayer AR; Antonucci LA; Fazio L; Pergola G; Bertolino A; Díaz-Caneja CM; Janssen J; Lois NG; Arango C; Tomyshev AS; Lebedeva I; Cervenka S; Sellgren CM; Georgiadis F; Kirschner M; Kaiser S; Hajek T; Skoch A; Spaniel F; Kim M; Bin Kwak Y; Oh S; Kwon JS; James A; Bakker G; Knöchel C; Stäblein M; Oertel V; Uhlmann A; Howells FM; Stein DJ; Temmingh HS; Diaz-Zuluaga AM; Pineda-Zapata JA; López-Jaramillo C; Homan S; Ji E; Surbeck W; Homan P; Fisher SE; Franke B; Glahn DC; Gur RC; Hashimoto R; Jahanshad N; Luders E; Medland SE; Thompson PM; Turner JA; van Erp TGM; Francks C
Corrigendum: MOLECULAR PSYCHIATRY. 2022;27(3):1855
GRK3 deficiency elicits brain immune activation and psychosis (May, 10.1038/s41380-021-01106-0, 2021)
Sellgren CM; Imbeault S; Larsson MK; Oliveros A; Nilsson IAK; Codeluppi S; Orhan F; Bhat M; Tufvesson-Alm M; Gracias J; Kegel ME; Zheng Y; Faka A; Svedberg M; Powell SB; Caldwell S; Kamenski ME; Vawter MP; Schulmann A; Goiny M; Svensson CI; Hokfelt T; Schalling M; Schwieler L; Cervenka S; Choi D-S; Landen M; Engberg G; Erhardt S
Review: PHARMACOLOGICAL REVIEWS. 2022;74(1):141-206
Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development-Current State-of-the-Art and Future Perspectives
Youhanna S; Kemas AM; Preiss L; Zhou Y; Shen JX; Cakal SD; Paqualini FS; Goparaju SK; Shafagh RZ; Lind JU; Sellgren CM; Lauschke VM
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2022;47:378-379
Proteomic Plasma Profiling of Patients With First-Episode Psychosis Identifies Inflammatory Markers Associated With Illness Severity
Erhardt S; Schwieler L; Sellgren CM; Eren F; Cervenka S; Piehl F; Bergman HF; Orhan F; Engberg G
Preprint: MEDRXIV. 2021
Cerebrospinal fluid concentration of complement component 4A is increased in first-episode schizophrenia
Gracias J; Orhan F; Hörbeck E; Holmén-Larsson J; Khanlarkani N; Malwade S; Goparaju S; Schwieler L; Fatourus-Bergman H; Pelanis A; Goold C; Goulding A; Annerbrink K; Isgren A; Sparding T; Schalling M; Yañez VC; Göpfert J; Nilsson J; Brinkmalm A; Blennow K; Zetterberg H; Engberg G; Piehl F; Sheridan S; Perlis R; Cervenka S; Erhardt S; Landen M; Sellgren C
Preprint: RESEARCH SQUARE. 2021
SARS-CoV-2 Neurotropism and Single Cell Responses in Brain Organoids Containing Innately Developing Microglia
Samudyata S; Oliveira A; Malwade S; de Sousa NR; Goparaju S; Orhan F; Steponaviciute L; Sheridan S; Perlis R; Rothfuchs A; Sellgren C
Preprint: BIORXIV. 2021
SARS-CoV-2 promotes microglial synapse elimination in human brain organoids
Samudyata; Oliveira AO; Malwade S; de Sousa NR; Goparaju S; Lekander JG; Orhan F; Steponaviciute L; Schalling M; Sheridan S; Perlis R; Rothfuchs A; Sellgren C
Conference publication: BIOLOGICAL PSYCHIATRY. 2021;89(9):S34
Genomic Variation Within the C4 Locus and Cerebro-spinal Fluid Levels of C4 Isotype Proteins in Acute and Chronic Schizophrenia
Gracias J; Horbeck E; Holmen-Larsson J; Pelanis A; Goold C; Goulding A; Annerbrink K; Isgren A; Sparding T; Blennow K; Zetterberg H; Vuijk P; Doyle AAE; Sheridan S; Perlis R; Landen M; Sellgren C
Preprint: BIORXIV. 2020;BIORXIV
Umbilical cord blood derived microglia-like cells to model COVID-19 exposure.
Sheridan SD; Thanos JM; De Guzman RM; McCrea LT; Horng J; Fu T; Sellgren CM; Perlis RH; Edlow AG
Review: FRONTIERS IN PSYCHIATRY. 2020;11:586083
Lithium and the Interplay Between Telomeres and Mitochondria in Bipolar Disorder
Lundberg M; Millischer V; Backlund L; Martinsson L; Stenvinkel P; Sellgren CM; Lavebratt C; Schalling M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S193-S194
The genetic risk for bipolar disorder predicts cortical thickness of the medial orbitofrontal cortex in patients and healthy controls
Abe C; Ossler W; Liberg B; Song J; Sarah B; Petrovic P; Ekman CJ; Sellgren C; Ingvar M; Landen M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S341
Large-scale serum biomarker profiling in patients with bipolar disorder
Palsson E; Jakobsson J; Isgren A; Sellgren C; Ekman CJ; Holmen-Larsson J; Landen M
Conference publication: GLIA. 2019;67:E325
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
Gracias J; Watmuff B; Biag J; Thanos J; Whittredge P; Fu T; Worringer K; Brown H; Wang J; Kaykas A; Karmacharya R; Goold C; Sheridan S; Sellgren C; Perlis R
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2019;44(SUPPL 1):490-491
Role of GRK3 in Brain Immune Activation and Psychosis
Erhardt S; Sellgren CM; Schwieler L; Imbeault S; Engberg G
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2019;44(SUPPL 1):169-170
Synaptic Elimination in First-Episode Psychosis Subjects
Engberg G; Xu C; Sellgren C; Fatouros-Bergman H; Blennow K; Zetterberg H; Brinkmalm A; Erhardt S
Letter: SCHIZOPHRENIA RESEARCH. 2018;195:406-408
First-episode psychosis patients display increased plasma IL-18 that correlates with cognitive dysfunction
Orhan F; Fatouros-Bergman H; Schwieler L; Cervenka S; Flyckt L; Sellgren CM; Engberg G; Erhardt S
Preprint: BIORXIV. 2017
Increased microglial synapse elimination in patient-specific models of schizophrenia
Sellgren CM; Gracias J; Watmuff B; Goold CP; Thanos JM; Fu T; Karmacharya R; Brown HE; Wang J; Sheridan SD; Perlis RH
Conference publication: BIPOLAR DISORDERS. 2017;19:115
Proteome-wide study of cerebrospinal fluid biomarkers for bipolar disorder
Larsson JH; Holtta M; Sellgren CM; Zetterberg H; Blennow K; Landen M; Gobom J
Conference publication: BIPOLAR DISORDERS. 2017;19:126
Altered cerebrospinal monoamine metabolite concentrations in bipolar disorder
Palsson E; Ryden E; Pelanis A; Zetterberg H; Blennow K; Sellgren C; Landen M
Conference publication: BIPOLAR DISORDERS. 2017;19:39-40
Cognitive impairments in bipolar disorder
Sparding T; Silander K; Palsson E; Ostlind J; Sellgren C; Ekman CJ; Joas E; Hansen S; Landen M
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2017;42:S220-S221
First-Episode Psychosis Patients Display Increased Plasma IL-18 That Correlates With Cognitive Dysfunctions
Schwieler L; Orhan F; Fatouros-Bergman H; Cervenka S; Flyckt L; Farde L; Sellgren CM; Engberg G; Erhardt S
Conference publication: BIOLOGICAL PSYCHIATRY. 2016;79(9):338S-339S
An Enzyme in the Kynurenine Pathway That Governs Vulnerability to Develop Suicidal Behavior
Brundin L; Sellgren C; Lim C; Grit J; Palsson E; Landen M; Brundin P; Fuchs D; Postolache T; Traskman-Bendz L; Guillemin G; Erhardt S
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S429-S430
Microglial activation in mood stabilised bipolar disorder patients
Jakobsson J; Isgren A; Palsson E; Ekman CJ; Johansson AGM; Sellgren C; Blennow K; Zetterberg H; Landen M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S426
Cerebrospinal fluid biomarkers of neurodegeneration affect cognitive functions in bipolar disorder but not healthy controls
Rolstad S; Jakobsson J; Sparding T; Sellgren C; Ekman CJ; Blennow KAJ; Zetterberg H; Palson E; Landen M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S423-S424
Sense of coherence as a predictor of suicide attempts in bipolar disorder
Palsson E; Lundberg U; Johnson L; Ekman CJ; Sellgren C; Landen M
Thesis / dissertation: 2014
On neuroinflammation in psychotic disorders
Sellgren, Carl
Conference publication: BIPOLAR DISORDERS. 2014;16:65
An inflammatory pathway linked to psychosis in bipolar disorder
Sellgren C; Kegel ME; Bergen SE; Ekman CJ; Olsson S; Larsson M; Sullivan PF; Sklar P; Purcell S; Smoller JW; Magnusson PKE; Hultman CM; Walther-Jallow L; Svensson CI; Lichtenstein P; Engberg G; Erhardt S; Landen M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2013;23:S385-S386
Cerebrospinal fluid cytokine concentrations in bipolar disorder patients and healthy controls
Isgren A; Jakobsson J; Palsson E; Ekman CJ; Johansson A; Sellgren C; Blennow K; Zetterberg H; Landen M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2013;23:S376-S377
Associations between cerebrospinal fluid markers and on-going medical treatment in patients with bipolar disorder
Jakobsson J; Palsson E; Bjerke M; Olsson B; Ekman CJ; Sellgren C; Johansson AGM; Blennow K; Zetterberg H; Landen M
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2013;23:S94-S95
Cerebrospinal fluid biomarkers of brain injury in bipolar disorder
Jakobsson J; Palsson E; Ekman CJ; Sellgren C; Johansson AGM; Zetterberg H; Blennow K; Landen M
Conference publication: BIPOLAR DISORDERS. 2011;13:87
Plasticity related gene 5, kynurenic acid, and psychotic features in bipolar disorder
Sellgren C; Olsson S; Lichtenstein P; Erhardt S; Engberg G; Grankvist A; Landen M
Preprint: BIORXIV.
Oligodendrocyte precursor cells engulf synapses in a model of the developing human forebrain
Gkogka A; Malwade S; Koskuvi M; Bose R; Ceccatelli S; Koistinaho J; Tiihonen J; Schalling M; Samudyata; Sellgren CM
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Employments

Researcher, Department of Physiology and Pharmacology, Karolinska Institutet, 2017-
Assistant Professor, Department of Physiology and Pharmacology, Karolinska Institutet, 2020-2026

Degrees and Education

Associate Professor, Karolinska Institutet, 2023
Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2014
University Medical Degree, Karolinska Institutet, 2004

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