Camilla Koolmeister

Publications
Public outreach and news

Articles

Article: NATURE METABOLISM. 2024;6(6):1024-1035
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity
Jiang S; Yuan T; Rosenberger FA; Mourier A; Dragano NRV; Kremer LS; Rubalcava-Gracia D; Hansen FM; Borg M; Mennuni M; Filograna R; Alsina D; Misic J; Koolmeister C; Papadea P; de Angelis MH; Ren L; Andersson O; Unger A; Bergbrede T; Di Lucrezia R; Wibom R; Zierath JR; Krook A; Giavalisco P; Mann M; Larsson N-G
Article: NPJ PARKINSON'S DISEASE. 2024;10(1):93
PARKIN is not required to sustain OXPHOS function in adult mammalian tissues
Filograna R; Gerlach J; Choi H-N; Rigoni G; Barbaro M; Oscarson M; Lee S; Tiklova K; Ringner M; Koolmeister C; Wibom R; Riggare S; Nennesmo I; Perlmann T; Wredenberg A; Wedell A; Motori E; Svenningsson P; Larsson N-G
Article: JCI INSIGHT. 2023;8(17):e167656
Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations
Zhang J; Koolmeister C; Han J; Filograna R; Hanke L; Adori M; Sheward DJ; Teifel S; Gopalakrishna S; Shao Q; Liu Y; Zhu K; Harris RA; Mcinerney G; Murrell B; Aoun M; Baeckdahl L; Holmdahl R; Pekalski M; Wedell A; Engvall M; Wredenberg A; Hedestam GBK; Dopico XC; Rorbach J
Article: PLOS GENETICS. 2023;19(1):e1010573
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA
Kremer LS; Bozhilova LV; Rubalcava-Gracia D; Filograna R; Upadhyay M; Koolmeister C; Chinnery PF; Larsson N-G
Article: NUCLEIC ACIDS RESEARCH (NAR). 2022;50(15):8749-8766
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion
Misic J; Milenkovic D; Al-Behadili A; Xie X; Jiang M; Jiang S; Filograna R; Koolmeister C; Siira SJ; Jenninger L; Filipovska A; Clausen AR; Caporali L; Valentino ML; La Morgia C; Carelli V; Nicholls TJ; Wredenberg A; Falkenberg M; Larsson N-G
Article: LIFE SCIENCE ALLIANCE. 2021;4(11):e202101034
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo
Bonekamp NA; Jiang M; Motori E; Villegas RG; Koolmeister C; Atanassov I; Mesaros A; Park CB; Larsson N-G
Article: PLOS GENETICS. 2021;17(9):e1009822
Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response
Filograna R; Lee S; Tiklova K; Mennuni M; Jonsson V; Ringner M; Gillberg L; Sopova E; Shupliakov O; Koolmeister C; Olson L; Perlmann T; Larsson N-G
Article: EMBO MOLECULAR MEDICINE. 2020;12(7):e11659
FBXL4 deficiency increases mitochondrial removal by autophagy
Alsina D; Lytovchenko O; Schab A; Atanassov I; Schober FA; Jiang M; Koolmeister C; Wedell A; Taylor RW; Wredenberg A; Larsson N-G
Article: MOLECULAR CELL. 2019;76(5):784-796.e6
Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria
Nicholls TJ; Spahr H; Jiang S; Siira SJ; Koolmeister C; Sharma S; Kauppila JHK; Jiang M; Kaever V; Rackham O; Chabes A; Falkenberg M; Filipovska A; Larsson N-G; Gustafsson CM
Article: EMBO REPORTS. 2019;20(6):embr201948101
TEFM regulates both transcription elongation and RNA processing in mitochondria
Jiang S; Koolmeister C; Misic J; Siira S; Kuehl I; Ramos ES; Miranda M; Jiang M; Posse V; Lytovchenko O; Atanassov I; Schober FA; Wibom R; Hultenby K; Milenkovic D; Gustafsson CM; Filipovska A; Larsson N-G
Article: SCIENCE ADVANCES. 2019;5(4):eaav9824
Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse
Filograna R; Koolmeister C; Upadhyay M; Pajak A; Clemente P; Wibom R; Simard ML; Wredenberg A; Freyer C; Stewart JB; Larsson NG
Article: NUCLEIC ACIDS RESEARCH (NAR). 2014;42(6):3638-3647
The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation
Posse V; Hoberg E; Dierckx A; Shahzad S; Koolmeister C; Larsson N-G; Wilhelmsson LM; Hallberg BM; Gustafsson CM
Article: NATURE GENETICS. 2012;44(11):1282-1285
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
Freyer C; Cree LM; Mourier A; Stewart JB; Koolmeister C; Milenkovic D; Wai T; Floros VI; Hagstrom E; Chatzidaki EE; Wiesner RJ; Samuels DC; Larsson N-G; Chinnery PF
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2007;27(10):2142-2149
Platelet-derived growth factor receptor-β constitutive activity promotes angiogenesis in vivo and in vitro
Magnusson PU; Looman C; Ahgren A; Wu Y; Claesson-Welsh L; Heuchel RL
Article: PLACENTA. 2007;28(5-6):412-420
Expression and function of the gene encoding the voltage-dependent calcium channel β3-subunit in the mouse placenta
Singh U; Sun T; Looman C; Heuchel R; Elliott R; Freichel A; Meissner A; Flockerzi V; Fundele R
Article: INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 2007;51(5):361-370
An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta
Looman C; Sun T; Yu Y; Zieba A; Ahgren A; Feinstein R; Forsberg H; Hellberg C; Heldin C-H; Zhang X-Q; Forsberg-Nilsson K; Khoo N; Fundele R; Heuchel R
Article: MAMMALIAN GENOME. 2004;15(1):35-40
A novel Krüppel-Associated Box identified in a panel of mammalian zinc finger proteins.
Looman C; Hellman L; Abrink M
Article: DNA AND CELL BIOLOGY. 2003;22(8):489-496
MZF6D, a novel KRAB zinc-finger gene expressed exclusively in meiotic male germ cells.
Looman C; Mark C; Abrink M; Hellman L
Article: IN VIVO. 2003;17(1):1-4
Fetal antigen 1 (FA1) in the adult rat adrenal gland, ovary and pituitary gland.
Hedlund GP; Carlsson HE; Shieck E; Nilsson I; Lundblad C; Arons S; Iversen AK; Looman C; Jensen HE; Hau J
Article: MOLECULAR BIOLOGY AND EVOLUTION (MBE). 2002;19(12):2118-2130
KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution.
Looman C; Abrink M; Mark C; Hellman L
Article: DNA AND CELL BIOLOGY. 2001;20(5):275-286
Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19.
Mark C; Looman C; Abrink M; Hellman L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(4):1422-1426
Conserved interaction between distinct Krüppel-associated box domains and the transcriptional intermediary factor 1 beta.
Abrink M; Ortiz JA; Mark C; Sanchez C; Looman C; Hellman L; Chambon P; Losson R
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Editorial comment: NATURE METABOLISM. 2020;2(8):673-675
Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos
Sharma S; Koolmeister C; Phong T; Nilsson AK; Larsson N-G; Chabes A
Letter: NATURE. 2014;514(7521):E7-11
POLRMT does not transcribe nuclear genes
Kuehl I; Kukat C; Ruzzenente B; Milenkovic D; Mourier A; Miranda M; Koolmeister C; Falkenberg M; Larsson N-G

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