Cagla Sahin

About me
Publications
Public outreach and news

About me

I'm a postdoctoral fellow at KI and at Copenhagen University. I'm working
with protein biophysics and structural biology, focusing on intrinsically
disordered proteins, amyloids and phase separation.
Novo Nordisk Fonden Postdoctoral Fellowship 2019-2023

Articles

Article: NATURE COMMUNICATIONS. 2024;15(1):1865
A druggable conformational switch in the c-MYC transactivation domain
Lama D; Vosselman T; Sahin C; Liano-Pons J; Cerrato CP; Nilsson L; Teilum K; Lane DP; Landreh M; Arsenian Henriksson M
Article: NATURE PROTOCOLS. 2023;18(12):3653-3661
Advances in mass spectrometry to unravel the structure and function of protein condensates
Sahin C; Leppert A; Landreh M
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2023;145(19):10659-10668
Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures
Sahin C; Motso A; Gu X; Feyrer H; Lama D; Arndt T; Rising A; Gese GV; Haellberg BM; Marklund EG; Schafer NP; Petzold K; Teilum K; Wolynes PG; Landreh M
Article: PNAS NEXUS. 2023;2(2):pgac303
A "grappling hook" interaction connects self-assembly and chaperone activity of Nucleophosmin 1
Saluri M; Leppert A; Gese GV; Sahin C; Lama D; Kaldmae M; Chen G; Elofsson A; Allison TM; Arsenian-Henriksson M; Johansson J; Lane DP; Hallberg BM; Landreh M
Article: MOLECULAR & CELLULAR PROTEOMICS. 2022;21(10):100413
Mass Spectrometry and Machine Learning Reveal Determinants of Client Recognition by Antiamyloid Chaperones
Osterlund N; Vosselman T; Leppert A; Graslund A; Jornvall H; Ilag LL; Marklund EG; Elofsson A; Johansson J; Sahin C; Landreh M
Article: NATURE COMMUNICATIONS. 2022;13(1):4695
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform
Arndt T; Jaudzems K; Shilkova O; Francis J; Johansson M; Laity PR; Sahin C; Chatterjee U; Kronqvist N; Barajas-Ledesma E; Kumar R; Chen G; Stromberg R; Abelein A; Langton M; Landreh M; Barth A; Holland C; Johansson J; Rising A
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2022;144(27):11949-11954
Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization
Sahin C; Osterlund EC; Osterlund N; Costeira-Paulo J; Pedersen JN; Christiansen G; Nielsen J; Gronnemose AL; Amstrup SK; Tiwari MK; Rao RSP; Bjerrum MJ; Ilag LL; Davies MJ; Marklund EG; Pedersen JS; Landreh M; Moller IM; Jorgensen TJD; Otzen DE
Article: STRUCTURE. 2022;30(5):733-742.e7
A "spindle and thread"mechanism unblocks p53 translation N-terminal disorder
Kaldmae M; Vosselman T; Zhong X; Lama D; Chen G; Saluri M; Kronqvist N; Siau JW; Ng AS; Ghadessy FJ; Sabatier P; Vojtesek B; Sarr M; Sahin C; Osterlund N; Ilag LL; Vaananen VA; Sedimbi S; Arsenian-Henriksson M; Zubarev RA; Nilsson L; Koeck PJB; Rising A; Abelein A; Fritz N; Johansson J; Lane DP; Landreh M
Article: JACS AU. 2021;1(12):2385-2393
Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry
Abramsson ML; Sahin C; Hopper JTS; Branca RMM; Danielsson J; Xu M; Chandler SA; Osterlund N; Ilag LL; Leppert A; Costeira-Paulo J; Lang L; Teilum K; Laganowsky A; Benesch JLP; Oliveberg M; Robinson CV; Marklund EG; Allison TM; Winther JR; Landreh M
Article: SCIENCE ADVANCES. 2021;7(27):eabh3805
Order and disorder-An integrative structure of the full-length human growth hormone receptor
Kassem N; Araya-Secchi R; Bugge K; Barclay A; Steinocher H; Khondker A; Wang Y; Lenard AJ; Buerck J; Sahin C; Ulrich AS; Landreh M; Pedersen MC; Rheinstaedter MC; Pedersen PA; Lindorff-Larsen K; Arleth L; Kragelund BB
Article: CHEMICAL COMMUNICATIONS. 2021;57(12):1450-1453
Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions
Sahin C; Osterlund N; Leppert A; Johansson J; Marklund EG; Benesch JLP; Ilag LL; Allison TM; Landreh M
Article: BIOCHIMIE. 2021;180:121-133
Molecular characteristics of porcine alpha-synuclein splicing variants
Larsen K; Baek R; Sahin C; Kjaer L; Christiansen G; Nielsen J; Farajzadeh L; Otzen DE
Article: ANALYTICAL CHEMISTRY. 2020;92(18):12297-12303
Predicting the Shapes of Protein Complexes through Collision Cross Section Measurements and Database Searches
Landreh M; Sahin C; Gault J; Sadeghi S; Drum CL; Uzdavinys P; Drew D; Allison TM; Degiacomi MT; Marklund EG
Article: THE FEBS JOURNAL. 2020;287(13):2823-2833
High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry
Kaldmae M; Leppert A; Chen G; Sarr M; Sahin C; Nordling K; Kronqvist N; Gonzalvo-Ulla M; Fritz N; Abelein A; Lain S; Biverstal H; Jornvall H; Lane DP; Rising A; Johansson J; Landreh M
Article: ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2020;59(9):3523-3528
A Mass-Spectrometry-Based Approach to Distinguish Annular and Specific Lipid Binding to Membrane Proteins
Bolla JR; Corey RA; Sahin C; Gault J; Hummer A; Hopper JTS; Lane DP; Drew D; Allison TM; Stansfeld PJ; Robinson CV; Landreh M
Article: JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY. 2019;30(8):1385-1388
Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction
Kaldmae M; Osterlund N; Lianoudaki D; Sahin C; Bergman P; Nyman T; Kronqvist N; Ilag LL; Allison TM; Marklund EG; Landreh M
Article: PROTEIN SCIENCE. 2019;28(6):1024-1030
A strategy for the identification of protein architectures directly from ion mobility mass spectrometry data reveals stabilizing subunit interactions in light harvesting complexes
Kaldmae M; Sahin C; Saluri M; Marklund EG; Landreh M
Article: ACS NANO. 2019;13(3):3243-3256
Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein
Mohammad-Beigi H; Hosseini A; Adeli M; Ejtehadi MR; Christiansen G; Sahin C; Tu Z; Tavakol M; Dilmaghani-Marand A; Nabipour I; Farzadfar F; Otzen DE; Mahmoudi M; Hajipour MJ

All other publications

Letter: NANO LETTERS. 2023;23(12):5836-5841
Liquid-Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain
Leppert A; Chen G; Lama D; Sahin C; Railaite V; Shilkova O; Arndt T; Marklund EG; Lane DP; Rising A; Landreh M
Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2020;48(2):547-558
Scratching the surface: native mass spectrometry of peripheral membrane protein complexes
Sahin C; Reid DJ; Marty MT; Landreh M

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