Brinton Seashore-Ludlow

Brinton Seashore-Ludlow

Senior Research Specialist
Telephone: +46852487873
Visiting address: Tomtebodavägen 23B, SciLifeLab, 17165 Stockholm
Postal address: K7 Onkologi-Patologi, K7 Forskning Kallioniemi SeashoreLudlow, 171 77 Stockholm
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About me

  • I currently hold two positions at the Karolinska Institute (KI). I am a team
    leader in the larger group of Olli Kallioniemi at the department of
    Oncology-Pathology. I am a group leader at SciLifeLab, and head of the
    biology team at Chemical Biology Consortium Sweden [1] (CBCS) KI node.
    [1] https://www.scilifelab.se/facilities/cbcs/

Research

  • .... Our ultimate goal is to promote the move away from one-size-fits-all
    therapies to improve patient outcome through treatment stratification
    and tailoring. Despite advances in precision medicine diagnostics, there
    are still major opportunities to improve individualized patient care
    throughout the entire health care value chain, spanning from preclinical
    studies in drug discovery through to the design of precision
    diagnostics. Research in my team focuses on challenges central to these
    fields, developing technologies and disease models that enable direct
    measurement of patient response to treatment /ex vivo /and investigation
    of the molecular determinants of drug response. Such methods and model
    systems are critical to improve the study of disease biology, identify
    and validate new drug targets, correctly prioritize drug candidates for
    clinical trials, uncover potential biomarkers for future patient
    stratification and have even recently been used successfully as
    diagnostics to match patients to effective treatments.
    .... Our translational research group and surrounding team of clinicians and
    experts has two major themes as described below united by the main goal
    of investigating drug response and biomarkers in primary patient cells
    and other near-patient models of disease.
    ....

Teaching

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