Arne Lindqvist

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Articles

Article: MOLECULAR CELL. 2021;81(24):5007-5024.e9
Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
Wiegard A; Kuzin V; Cameron DP; Grosser J; Ceribelli M; Mehmood R; Ballarino R; Valant F; Grochowski R; Karabogdan I; Crosetto N; Lindqvist A; Bizard AH; Kouzine F; Natsume T; Baranello L
Article: LIFE SCIENCE ALLIANCE. 2021;4(3):e202000980
Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1
Cascales HS; Burdova K; Middleton A; Kuzin V; Mullers E; Stoy H; Baranello L; Macurek L; Lindqvist A
Article: CELLS. 2020;9(9):E2126-2126
FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery
Lafranchi L; Mullers E; Rutishauser D; Lindqvist A
Article: NUCLEIC ACIDS RESEARCH (NAR). 2020;48(10):5777-5787
Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers
Verheyen T; Fang T; Lindenhofer D; Wang Y; Akopyan K; Lindqvist A; Hogberg B; Teixeira AI
Article: CELL CHEMICAL BIOLOGY. 2019;26(10):1436-1449.e5
Neutralization of the Positive Charges on Histone Tails by RNA Promotes an Open Chromatin Structure
Dueva R; Akopyan K; Pederiva C; Trevisan D; Dhanjal S; Lindqvist A; Farnebo M
Article: SCIENTIFIC REPORTS. 2019;9(1):13758
The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2
Vakkilainen S; Skoog T; Einarsdottir E; Middleton A; Pekkinen M; Ohman T; Katayama S; Krjutskov K; Kovanen PE; Varjosalo M; Lindqvist A; Kere J; Makitie O
Article: CELL REPORTS. 2019;26(7):1691-1700.e5
Mapping Metabolic Events in the Cancer Cell Cycle Reveals Arginine Catabolism in the Committed SG₂M Phase
Roci I; Watrous JD; Lagerborg KA; Lafranchi L; Lindqvist A; Jain M; Nilsson R
Article: MOLECULAR CELL. 2018;71(1):117-128.e3
DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation
Lemmens B; Hegarat N; Akopyan K; Sala-Gaston J; Bartek J; Hochegger H; Lindqvist A
Article: EMBO JOURNAL. 2017;36(14):2161-2176
ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration
Jaiswal H; Benada J; Mullers E; Akopyan K; Burdova K; Koolmeister T; Helleday T; Medema RH; Macurek L; Lindqvist A
Article: AGING CELL. 2017;16(3):575-584
Residual Cdk1/2 activity after DNA damage promotes senescence
Mullers E; Cascales HS; Burdova K; Macurek L; Lindqvist A
Article: STEM CELL REPORTS. 2016;6(5):643-651
Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells
Braune E-B; Tsoi YL; Phoon YP; Landor S; Cascales HS; Ramskold D; Deng Q; Lindqvist A; Lian X; Sahlgren C; Jin S-B; Lendahl U
Article: METHODS IN MOLECULAR BIOLOGY. 2016;1342:173-183
Cell Cycle Dynamics of Proteins and Post-translational Modifications Using Quantitative Immunofluorescence.
Akopyan K; Lindqvist A; Müllers E
Article: FRONTIERS IN ONCOLOGY. 2015;5:132
Spatial separation of Plk1 phosphorylation and activity
Bruinsma W; Aprelia M; Kool J; Macurek L; Lindqvist A; Medema RH
Article: FRONTIERS IN GENETICS. 2015;6:63
Bystander communication and cell cycle decisions after DNA damage
Jaiswal H; Lindqvist A
Article: PLOS GENETICS. 2014;10(10):e1004680
The Chromosomal Association of the Smc5/6 Complex Depends on Cohesion and Predicts the Level of Sister Chromatid Entanglement
Jeppsson K; Carlborg KK; Nakato R; Berta DG; Lilienthal I; Kanno T; Lindqvist A; Brink MC; Dantuma NP; Katou Y; Shirahige K; Sjogren C
Article: ONCOTARGET. 2014;5(18):8379-8392
Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism
Waraky A; Akopyan K; Parrow V; Stroemberg T; Axelson M; Abrahmsen L; Lindqvist A; Larsson O; Aleem E
Article: CELL CYCLE. 2014;13(17):2733-2743
Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase
Mullers E; Cascales HS; Jaiswal H; Saurin AT; Lindqvist A
Article: CELL DEATH AND DISEASE. 2014;5(5):e1235
Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H₂O₂
Peng X; Mandal PK; Kaminskyy VO; Lindqvist A; Conrad M; Arner ESJ
Article: MOLECULAR CANCER THERAPEUTICS. 2014;13(5):1054-1066
Centmitor-1, a Novel Acridinyl-Acetohydrazide, Possesses Similar Molecular Interaction Field and Antimitotic Cellular Phenotype as Rigosertib, ON 01910.Na
Maki-Jouppila JHE; Laine LJ; Rehnberg J; Narvi E; Tiikkainen P; Hukasova E; Halonen P; Lindqvist A; Kallio L; Poso A; Kallio MJ
Article: MOLECULAR CELL. 2014;53(5):843-853
Assessing Kinetics from Fixed Cells Reveals Activation of the Mitotic Entry Network at the S/G2 Transition
Akopyan K; Cascales HS; Hukasova E; Saurin AT; Mullers E; Jaiswal H; Hollman DAA; Kops GJPL; Medema RH; Lindqvist A
Article: JOURNAL OF CELL SCIENCE. 2014;127(4):801-811
Bora and Aurora-A continue to activate Plk1 in mitosis
Bruinsma W; Macurek L; Freire R; Lindqvist A; Medema RH
Article: CELL CYCLE. 2014;13(11):1727-1736
Phosphorylation-mediated stabilization of Bora in mitosis coordinates Plx1/Plk1 and Cdk1 oscillations
Feine O; Hukasova E; Bruinsma W; Freire R; Fainsod A; Gannon J; Mahbubani HM; Lindqvist A; Brandeis M
Article: CELL CYCLE. 2014;13(7):1162-1170
Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning
Tame MA; Raaijmakers JA; van den Broek B; Lindqvist A; Jalink K; Medema RH
Article: CELL CYCLE. 2013;12(2):251-262
Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis
Macurek L; Benada J; Muellers E; Halim VA; Krejcikova K; Burdova K; Pechackova S; Hodny Z; Lindqvist A; Medema RH; Bartek J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;417(4):1248-1253
Functional characterization of the pleckstrin homology domain of a cellulose synthase from the oomycete Saprolegnia monoica
Fugelstad J; Brown C; Hukasova E; Sundqvist G; Lindqvist A; Bulone V
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2012;(59):e3410
Monitoring Kinase and Phosphatase Activities Through the Cell Cycle by Ratiometric FRET
Hukasova E; Cascales HS; Kumar SR; Lindqvist A
Article: ONCOGENE. 2010;29(15):2281-2291
Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition
Macurek L; Lindqvist A; Voets O; Kool J; Vos HR; Medema RH
Article: PLOS BIOLOGY. 2010;8(4):e1000350
Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry
Splinter D; Tanenbaum ME; Lindqvist A; Jaarsma D; Flotho A; Yu KL; Grigoriev I; Engelsma D; Haasdijk ED; Keijzer N; Demmers J; Fornerod M; Melchior F; Hoogenraad CC; Medema RH; Akhmanova A
Article: EMBO JOURNAL. 2009;28(20):3196-3206
Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression
Lindqvist A; de Bruijn M; Macurek L; Bras A; Mensinga A; Bruinsma W; Voets O; Kranenburg O; Medema RH
Article: NATURE. 2008;455(7209):119-U88
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
Macurek L; Lindqvist A; Lim D; Lampson MA; Klompmaker R; Freire R; Clouin C; Taylor SS; Yaffe MB; Medema RH
Article: PLOS BIOLOGY. 2007;5(5):e123-1137
Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression
Lindqvist A; van Zon W; Rosenthal CK; Wolthuis RMF
Article: JOURNAL OF CELL BIOLOGY. 2005;171(1):35-45
Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome
Lindqvist A; Källström H; Lundgren A; Barsoum E; Rosenthal CK
Article: EXPERIMENTAL CELL RESEARCH. 2005;303(1):89-100
Cdc25A localisation and shuttling:: characterisation of sequences mediating nuclear export and import
Källström H; Lindqvist A; Pospisil V; Lundgren A; Rosenthal CK
Article: JOURNAL OF CELL SCIENCE. 2004;117(21):4979-4990
Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress
Lindqvist A; Källström H; Rosenthal CK
Article: MOLECULAR MICROBIOLOGY. 2001;42(5):1179-1188
Distribution of the Escherichia coli structural maintenance of chromosomes (SMC)-like protein MukB in the cell
den Blaauwen T; Lindqvist A; Löwe J; Nanninga N
Article: ANTONIE VAN LEEUWENHOEK. 2000;78(1):23-31
Roles of respiratory oxidases in protecting Escherichia coli K12 from oxidative stress
Lindqvist A; Membrillo-Hernández J; Poole RK; Cook GM
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All other publications

Book chapter: METHODS IN CELL BIOLOGY. 2024;p. 187-197
Using an ImageJ-based script to detect replication stress and associated cell cycle exit from G2 phase by fluorescence microscopy.
Lindqvist A; Hao Z; Akopyan K
Review: JOURNAL OF CELL BIOLOGY. 2019;218(12):3892-3902
DNA replication and mitotic entry: A brake model for cell cycle progression
Lemmens B; Lindqvist A
Editorial comment: AGING. 2017;9(10):2022-2023
How the cell cycle enforces senescence
Cascales HS; Muellers E; Lindqvist A
Review: TRENDS IN BIOCHEMICAL SCIENCES. 2011;36(11):578-584
Boosting and suppressing mitotic phosphorylation
Medema RH; Lindqvist A
Editorial comment: JOURNAL OF CELL BIOLOGY. 2010;189(2):197-199
Cyclin B-Cdk1 activates its own pump to get into the nucleus
Lindqvist A
Review: CANCER RESEARCH. 2009;69(11):4555-4558
Aurora-A and hBora Join the Game of Polo
Macurek L; Lindqvist A; Medema RH
Review: JOURNAL OF CELL BIOLOGY. 2009;185(2):193-202
The decision to enter mitosis: feedback and redundancy in the mitotic entry network
Lindqvist A; Rodriguez-Bravo V; Medema RH
Thesis / dissertation: 2005
Regulation of CDK dephosphorylation in mitotic entry
Lindqvist, Arne

Employments

Principal Researcher, Department of Cell and Molecular Biology, Karolinska Institutet, 2022-

Degrees and Education

Docent, Karolinska Institutet, 2016
Doctor Of Philosophy, Department of Cell and Molecular Biology, Karolinska Institutet, 2005

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