Antonio Lentini

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About me

Antonio Lentini is a computational biologist and SSMF post-doctoral
researcher studying transcriptional regulation and dosage compensation.

Articles

Article: NATURE NANOTECHNOLOGY. 2024;19(2):237-245
Multivalent insulin receptor activation using insulin-DNA origami nanostructures
Spratt J; Dias JM; Kolonelou C; Kiriako G; Engstrom E; Petrova E; Karampelias C; Cervenka I; Papanicolaou N; Lentini A; Reinius B; Andersson O; Ambrosetti E; Ruas JL; Teixeira AI
Article: NATURE COMMUNICATIONS. 2024;15(1):465
Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force
Smyrlaki I; Foerdos F; Rocamonde-Lago I; Wang Y; Shen B; Lentini A; Luca VC; Reinius B; Teixeira AI; Hoegberg B
Article: NATURE NEUROSCIENCE. 2023;26(7):1245-1255
Esr1⁺ hypothalamic-habenula neurons shape aversive states
Calvigioni D; Fuzik J; Le Merre P; Slashcheva M; Jung F; Ortiz C; Lentini A; Csillag V; Graziano M; Nikolakopoulou I; Weglage M; Lazaridis I; Kim H; Lenzi I; Park H; Reinius B; Carlen M; Meletis K
Article: MED. 2022;3(9):636-643.e4
Clinical and Translational Report Monitoring of the SARS-CoV-2 Omicron BA.1/BA.2 lineage transition in the Swedish population reveals increased viral RNA levels in BA.2 cases
Lentini A; Pereira A; Winqvist O; Reinius B
Article: NATURE COMMUNICATIONS. 2022;13(1):1854
Elastic dosage compensation by X-chromosome upregulation
Lentini A; Cheng H; Noble JC; Papanicolaou N; Coucoravas C; Andrews N; Deng Q; Enge M; Reinius B
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(34):e2110758118
TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia
Bensberg M; Rundquist O; Selimovic A; Lagerwall C; Benson M; Gustafsson M; Vogt H; Lentini A; Nestor CE
Article: SCIENCE IMMUNOLOGY. 2021;6(56):eabb7800
Continuous human uterine NK cell differentiation in response to endometrial regeneration and pregnancy
Strunz B; Bister J; Jonsson H; Filipovic I; Crona-Guterstam Y; Kvedaraite E; Sleiers N; Dumitrescu B; Brannstrom M; Lentini A; Reinius B; Cornillet M; Willinger T; Gidlof S; Hamilton RS; Ivarsson MA; Bjorkstrom NK
Article: METHODS IN MOLECULAR BIOLOGY. 2021;2198:431-439
Analyzing DNA-Immunoprecipitation Sequencing Data.
Lentini A; Nestor CE
Article: BMC GENOMICS. 2020;21(1):769
DNA methylation in infants with low and high body fatness
Henriksson P; Lentini A; Altmaee S; Brodin D; Mueller P; Forsum E; Nestor CE; Lof M
Article: NATURE COMMUNICATIONS. 2020;11(1):4812
Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR
Smyrlaki I; Ekman M; Lentini A; de Sousa NR; Papanicolaou N; Vondracek M; Aarum J; Safari H; Muradrasoli S; Rothfuchs AG; Albert J; Hoegberg B; Reinius B
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: SCIENCE ADVANCES. 2020;6(12):eaay3335
No evidence for DNA N⁶-methyladenine in mammals
Douvlataniotis K; Bensberg M; Lentini A; Gylemo B; Nestor CE
Article: GENOME MEDICINE. 2019;11(1):47
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases
Gawel DR; Serra-Musach J; Lilja S; Aagesen J; Arenas A; Asking B; Bengner M; Bjorkander J; Biggs S; Ernerudh J; Hjortswang H; Karlsson J-E; Kopsen M; Lee EJ; Lentini A; Li X; Magnusson M; Martinez-Enguita D; Matussek A; Nestor CE; Schafer S; Seifert O; Sonmez C; Stjernman H; Tjarnberg A; Wu S; Akesson K; Shalek AK; Stenmarker M; Zhang H; Gustafsson M; Benson M
Article: EMBO JOURNAL. 2019;38(2):e98873
TCF/LEF dependent and independent transcriptional regulation of Wnt/β-catenin target genes
Doumpas N; Lampart F; Robinson MD; Lentini A; Nestor CE; Cantu C; Basler K
Article: NATURE METHODS. 2018;15(7):499-504
A reassessment of DNA-immunoprecipitation-based genomic profiling
Lentini A; Lagerwall C; Vikingsson S; Mjoseng HK; Douvlataniotis K; Vogt H; Green H; Meehan RR; Benson M; Nestor CE
Article: CELL REPORTS. 2016;16(2):559-570
5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4⁺ T Cells
Nestor CE; Lentini A; Nilsson CH; Gawel DR; Gustafsson M; Mattson L; Wang H; Rundquist O; Meehan RR; Klocke B; Seifert M; Hauck SM; Laumen H; Zhang H; Benson M
Article: JOURNAL OF IMMUNOLOGY RESEARCH. 2016;2016:5153184-6
Potential Involvement of Type I Interferon Signaling in Immunotherapy in Seasonal Allergic Rhinitis
Mattson L; Lentini A; Gawel DR; Badam TVS; Benson M; Ledin T; Nestor CE; Gustafsson M; Serra-Musach J; Bjorkander J; Xiang Z; Zhang H
Article: SCIENCE TRANSLATIONAL MEDICINE. 2015;7(313):313ra178
A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases
Gustafsson M; Gawel DR; Alfredsson L; Baranzini S; Bjorkander J; Blomgran R; Hellberg S; Eklund D; Ernerudh J; Kockum I; Konstantinell A; Lahesmaa R; Lentini A; Liljenstrom HRI; Mattson L; Matussek A; Mellergard J; Mendez M; Olsson T; Pujana MA; Rasool O; Serra-Musach J; Stenmarker M; Tripathi S; Viitala M; Wang H; Zhang H; Nestor CE; Benson M
Article: GENOME BIOLOGY. 2015;16(1):11
Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems
Nestor CE; Ottaviano R; Reinhardt D; Cruickshanks HA; Mjoseng HK; McPherson RC; Lentini A; Thomson JP; Dunican DS; Pennings S; Anderton SM; Benson M; Meehan RR
Article: PLOS GENETICS. 2014;10(1):e1004059
DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4⁺ T-Cell Population Structure
Nestor CE; Barrenas F; Wang H; Lentini A; Zhang H; Bruhn S; Jornsten R; Langston MA; Rogers G; Gustafsson M; Benson M

All other publications

Letter: CURRENT BIOLOGY. 2023;33(10):R395-R396
Limitations of X:autosome ratio as a measurement of X-chromosome upregulation
Lentini A; Reinius B
Review: METHODS IN MOLECULAR BIOLOGY. 2021;2198:37-50
Mapping DNA Methylation in Mammals: The State of the Art.
Lentini A; Nestor CE
Corrigendum: GENOME MEDICINE. 2020;12(1):37
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases (vol 11, 47, 2019)
Gawel DR; Serra-Musach J; Lilja S; Aagesen J; Arenas A; Asking B; Bengner M; Bjorkander J; Biggs S; Ernerudh J; Hjortswang H; Karlsson J-E; Kopsen M; Lee EJ; Lentini A; Li X; Magnusson M; Martinez-Enguita D; Matussek A; Nestor CE; Schafer S; Seifert O; Sonmez C; Stjernman H; Tjarnberg A; Wu S; Akesson K; Shalek AK; Stenmarker M; Zhang H; Gustafsson M; Benson M
Review: CURRENT OPINION IN CHEMICAL BIOLOGY. 2018;45:48-56
DNA methylation as a genomic marker of exposure to chemical and environmental agents
Meehan RR; Thomson JP; Lentini A; Nestor CE; Pennings S
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;132(4):1005-1008
Profiling of human CD4⁺ T-cell subsets identifies the T_H2-specific noncoding RNA GATA3-AS1
Zhang H; Nestor CE; Zhao S; Lentini A; Bohle B; Benson M; Wang H

Employments

Affiliated to Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2024-2025
Research Specialist, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2024-2024

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