After receiving my PhD at the Radboud University Nijmegen, The Netherlands, I joined the group of professor Ernfors in februari 2016 as a postdoctoral fellow (Rubicon). I am interested in a more fundamental understanding of glioblastoma biology.
I focus my studies on elucidating fundamental mechanisms that are required for glioblastoma development and progression.
The project involves state-of-the-art technologies including single cell RNA sequencing and CRISPR genome editing.
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG
Acta neuropathologica communications 2013;1():18-
Multivoxel H-1 MR spectroscopy is superior to contrast-enhanced MRI for response assessment after anti-angiogenic treatment of orthotopic human glioma xenografts and provides handles for metabolic targeting
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models
JOURNAL OF PATHOLOGY 2011;223(5):626-34
Protein tyrosine phosphatases in glioma biology
ACTA NEUROPATHOLOGICA 2010;119(2):157-75
The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response
NUCLEIC ACIDS RESEARCH 2009;37(2):322-35