Anita Lövgren Sandblom

Publications
Public outreach and news

Articles

Article: BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2024;131(9):1218-1228
Serum bile acid measurements in women of European and South Asian ethnicity with or without gestational diabetes mellitus: A cohort study
Schoonejans JM; Fan HM; Mitchell AL; Lovgren-Sandblom A; Sukumar N; Periyathambi N; Weldeselassie Y; Seed PT; Molinaro A; Marschall H-U; Saravanan P; Williamson C
Article: JHEP REPORTS. 2022;4(11):100561
Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis
Braadland PR; Schneider KM; Bergquist A; Molinaro A; Lovgren-Sandblom A; Henricsson M; Karlsen TH; Vesterhus M; Trautwein C; Hov JR; Marschall H-U
Article: BRAIN SCIENCES. 2022;12(11):1450
Ventriculoperitoneal Shunt Treatment Increases 7 Alpha Hy-Droxy-3-Oxo-4-Cholestenoic Acid and 24-Hydroxycholesterol Concentrations in Idiopathic Normal Pressure Hydrocephalus
Porru E; Edstrom E; Arvidsson L; Elmi-Terander A; Fletcher-Sandersjoo A; Sandblom AL; Hansson M; Duell F; Bjorkhem I
Article: DIABETES. 2022;71(4):837-852
Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus
Fan HM; Mitchell AL; Bellafante E; McIlvride S; Primicheru LI; Giorgi M; Eberini I; Syngelaki A; Lovgren-Sandblom A; Jones P; McCance D; Sukumar N; Periyathambi N; Weldeselassie Y; Hunt KF; Nicolaides KH; Andersson D; Bevan S; Seed PT; Bewick GA; Bowe JE; Fraternali F; Saravanan P; Marschall H-U; Williamson C
Article: CANCERS. 2021;13(18):4689
CYP3A Activity in End-of-Life Cancer Patients Measured by 4β-Hydroxycholesterol/cholesterol Ratio, in Men and Women
Bergstrom H; Frankling MH; Klasson C; Sandblom AL; Diczfalusy U; Bjorkhem-Bergman L
Article: JOURNAL OF HEPATOLOGY. 2021;74(5):1087-1096
Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations
Vasavan T; Deepak S; Jayawardane IA; Lucchini M; Martin C; Geenes V; Yang J; Lovgren-Sandblom A; Seed PT; Chambers J; Stone S; Kurlak L; Dixon PH; Marschall H-U; Gorelik J; Chappell L; Loughna P; Thornton J; Pipkin FB; Hayes-Gill B; Fifer WP; Williamson C
Article: SCANDINAVIAN JOURNAL OF CLINICAL AND LABORATORY INVESTIGATION. 2020;80(5):395-400
Further evidence for a continuous flux of bile acids into the brain: trapping of bile acids in subdural hematomas
Porru E; Edstrom E; Saeed AA; Eggertsen G; Lovgren-Sandblom A; Roda A; Bjorkhem I
Article: BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2019;126(13):1633-1640
Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study
Manna LB; Ovadia C; Lovgren-Sandblom A; Chambers J; Begum S; Seed P; Walker I; Chappell LC; Marschall H-U; Williamson C
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019;190:115-125
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods
Luetjohann D; Bjorkhem I; Friedrichs S; Kerksiek A; Lovgren-Sandblom A; Geilenkeuser W-J; Ahrends R; Andrade I; Ansorena D; Astiasaran I; Baila-Rueda L; Barriuso B; Becker S; Bretillon L; Browne RW; Caccia C; Ceglarek UH; Cenarro A; Crick PJ; Fauler G; Garcia-Llatas G; Gray R; Griffiths WJ; Gylling H; Harding S; Helmschrodt C; Iuliano L; Janssen H-G; Jones P; Kaipiainen L; Kannenberg F; Jesus Lagarda M; Leoni V; Lottenberg AM; MacKay DS; Matysik S; McDonald J; Menendez-Carreno M; Myrie SB; Nunes VS; Ostlund RE; Polisecki E; Ramos F; Rideout TC; Schaefer EJ; Schmitz G; Wang Y; Zerbinati C; Diczfalusy U; Schoett H-F
Article: JOURNAL OF CLINICAL APHERESIS. 2018;33(6):638-644
Therapeutic plasma exchange as a novel treatment for severe intrahepatic cholestasis of pregnancy: Case series and mechanism of action
Ovadia C; Lovgren-Sandblom A; Edwards LA; Langedijk J; Geenes V; Chambers J; Cheng F; Clarke L; Begum S; Noori M; Pusey C; Padmagirison R; Agarwal S; Peerless J; Cheesman K; Heneghan M; Elferink RO; Patel VC; Marschall H-U; Williamson C
Article: BIOCHIMIE. 2018;153:26-32
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods
Luetjohann D; Bjorkhem I; Friedrichs S; Kerksiek A; Geilenkeuser W-J; Lovgren-Sandblom A; Ansorena D; Astiasaran I; Baila-Rueda L; Barriuso B; Bretillon L; Browne RW; Caccia C; Cenarro A; Crick PJ; Fauler G; Garcia-Llatas G; Griffiths WJ; Iuliano L; Jesus Lagarda M; Leoni V; Lottenberg AM; Matysik S; McDonald J; Rideout TC; Schmitz G; Nunes VS; Wang Y; Zerbinati C; Diczfalusy U; Schoett H-F
Article: JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY. 2018;8(2):162-168
Circulating Fibroblast Growth Factor 19 in Portal and Systemic Blood
Johansson H; Mork L-M; Li M; Sandblom AL; Bjorkhem I; Hoijer J; Ericzon B-G; Jorns C; Gilg S; Sparrelid E; Isaksson B; Nowak G; Ellis E
Article: HEPATOLOGY. 2016;63(4):1287-1298
Prognostic and Mechanistic Potential of Progesterone Sulfates in Intrahepatic Cholestasis of Pregnancy and Pruritus Gravidarum
Abu-Hayyeh S; Ovadia C; Lieu T; Jensen DD; Chambers J; Dixon PH; Lovgren-Sandblom A; Bolier R; Tolenaars D; Kremer AE; Syngelaki A; Noori M; Williams D; Marin JJG; Monte MJ; Nicolaides KH; Beuers U; Oude-Elferink R; Seed PT; Chappell L; Marschall H-U; Bunnett NW; Williamson C
Article: JOURNAL OF LIPID RESEARCH. 2014;55(6):1165-1172
On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO
Bjorkhem I; Diczfalusy U; Lovgren-Sandblom A; Starck L; Jonsson M; Tallman K; Schirmer H; Ousager LB; Crick PJ; Wang Y; Griffiths WJ; Guengerich FP
Article: JOURNAL OF LIPID RESEARCH. 2014;55(2):313-318
7α-hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier
Saeed A; Floris F; Andersson U; Pikuleva I; Lovgren-Sandblom A; Bjerke M; Paucar M; Wallin A; Svenningsson P; Bjorkhem I
Article: PLOS ONE. 2014;9(1):e83828
The Reversed Feto-Maternal Bile Acid Gradient in Intrahepatic Cholestasis of Pregnancy Is Corrected by Ursodeoxycholic Acid
Geenes V; Lovgren-Sandblom A; Benthin L; Lawrance D; Chambers J; Gurung V; Thornton J; Chappell L; Khan E; Dixon P; Marschall H-U; Williamson C
Article: PLOS ONE. 2014;9(11):e113619
Cholesterol, Oxysterol, Triglyceride, and Coenzyme Q Homeostasis in ALS. Evidence against the Hypothesis That Elevated 27-Hydroxycholesterol Is a Pathogenic Factor
Wuolikainen A; Acimovic J; Loevgren-Sandblom A; Parini P; Andersen PM; Bjoerkhem I
Article: NEUROSCIENCE LETTERS. 2013;555:102-105
Oxysterols and Parkinson's disease: Evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease
Bjorkhem I; Lovgren-Sandblom A; Leoni V; Meaney S; Brodin L; Salveson L; Winge K; Palhagen S; Svenningsson P
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2013;36(4):739-747
Diagnostic Power of 24S-Hydroxycholesterol in Cerebrospinal Fluid: Candidate Marker of Brain Health
Leoni V; Solomon A; Lovgren-Sandblom A; Minthon L; Blennow K; Hansson O; Wahlund L-O; Kivipelto M; Bjorkhem I
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2013;75(6):1536-1540
A comparison of 4-hydroxycholesterol:cholesterol and 6-hydroxycortisol:cortisol as markers of CYP3A4 induction
Arrhen YM; Nylen H; Lovgren-Sandblom A; Kanebratt KP; Wide K; Diczfalusy U
Article: JOURNAL OF LIPID RESEARCH. 2013;54(4):1033-1043
On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1^-/- mice
Ali Z; Heverin M; Olin M; Acimovic J; Lovgren-Sandblom A; Shafaati M; Bavner A; Meiner V; Leitersdorf E; Bjorkhem I
Article: HEPATOLOGY. 2013;57(2):716-726
Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype
Abu-Hayyeh S; Papacleovoulou G; Lovgren-Sandblom A; Tahir M; Oduwole O; Jamaludin NA; Ravat S; Nikolova V; Chambers J; Selden C; Rees M; Marschall H-U; Parker MG; Williamson C
Article: PLOS ONE. 2013;8(11):e78550
Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism
Ellis ECS; Nauglers S; Parini P; Mork L-M; Jorns C; Zemack H; Sandblom AL; Bjorkhem I; Ericzon B-G; Wilson EM; Strom SC; Grompe M
Article: PLOS ONE. 2013;8(7):e68031
Sulphatation Does Not Appear to Be a Protective Mechanism to Prevent Oxysterol Accumulation in Humans and Mice
Acimovic J; Lovgren-Sandblom A; Olin M; Ali Z; Heverin M; Schuele R; Schoels L; Fischler B; Fickert P; Trauner M; Bjorkhem I
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;425(2):348-352
The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone
Acimovic J; Lovgren-Sandblom A; Eriksson LC; Bjorkhem-Bergman L
Article: JOURNAL OF LIPID RESEARCH. 2011;52(5):1004-1010
Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation
Shafaati M; Marutle A; Pettersson H; Lovgren-Sandblom A; Olin M; Pikuleva I; Winblad B; Nordberg A; Bjorkhem I
Article: JOURNAL OF LIPID RESEARCH. 2011;52(1):170-174
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: fact or fiction?
Bjorkhem I; Lovgren-Sandblom A; Piehl F; Khademi M; Pettersson H; Leoni V; Olsson T; Diczfalusy U
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1801(6):674-681
Marked variability in hepatic expression of cytochromes CYP7A1 and CYP27A1 as compared to cerebral CYP46A1. Lessons from a dietary study with omega 3 fatty acids in hamsters
Mast N; Shafaati M; Zaman W; Zheng W; Prusak D; Wood T; Ansari GAS; Loevgren-Sandblom A; Olin M; Bjorkhem I; Pikuleva I
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2010;30(6):1174-1180
Impaired Development of Atherosclerosis in Abcg1^-/- Apoe^-/- Mice Identification of Specific Oxysterols That Both Accumulate in Abcg1^-/- Apoe^-/- Tissues and Induce Apoptosis
Tarling EJ; Bojanic DD; Tangirala RK; Wang X; Lovgren-Sandblom A; Lusis AJ; Bjorkhem I; Edwards PA
Article: JOURNAL OF LIPID RESEARCH. 2010;51(1):169-181
Differential expression and function of ABCG1 and ABCG4 during development and aging
Bojanic DD; Tarr PT; Gale GD; Smith DJ; Bok D; Chen B; Nusinowitz S; Loevgren-Sandblom A; Bjoerkhem I; Edwards PA
Article: BMC GENOMICS. 2009;10:384
Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers
Rezen T; Viola T; Lovgren-Sandblom A; Bjorkhem I; Meyer UA; Rozman D
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2009;877(22):2081-2086
Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells
Acimovic J; Lovgren-Sandblom A; Monostory K; Rozman D; Golicnik M; Lutjohann D; Bjorkhem I
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2007;27(10):2191-2197
Studies on the cholesterol-free mouse -: Strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol
Heverin M; Meaney S; Brafman A; Shafir M; Olin M; Shafaati M; von Bahr S; Larsson L; Loevgren-Sandblom A; Diczfalusy U; Parini P; Feinstein E; Bjoerkhem I
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2007;856(1-2):15-19
Novel LC-MS/MS method for assay of 7α-hydroxy-4-cholesten-3-one in human plasma evidence for a significant extrahepatic metabolism
Lovgren-Sandblom A; Heverin M; Larsson H; Lundstrom E; Wahren J; Diczfalusy U; Bjorkhem I
Article: AMERICAN JOURNAL OF MEDICAL GENETICS, PART A. 2002;113(2):183-189
Simvastatin treatment in the SLO syndrome:: A safe approach?
Starck L; Lövgren-Sandblom A; Björkhem I
Article: JOURNAL OF INTERNAL MEDICINE. 2002;252(4):314-321
Cholesterol treatment forever?: The first Scandinavian trial of cholesterol supplementation in the cholesterol-synthesis defect Smith-Lemli-Opitz syndrome
Starck L; Lövgren-Sandblom A; Björkhem I
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Meeting abstract: JOURNAL OF HEPATOLOGY. 2014;60(1):S194
BIOCHEMICAL MARKERS FOR INTRAHEPATIC CHOLESTASIS OF PREGNANCY AND PRURITUS GRAVIDARUM IN WOMEN WITH GESTATIONAL PRURITUS
Ovadia C; Abu-Hayyeh S; Dixon PH; Chambers J; Lovgren-Sandblom A; Bolier R; Tolenaars D; Beuers U; Oude-Elferink R; Jansen E; Seed PT; Marschall H-U; Williamson C

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