Alexandra Circiumaru

Publications
CV
Public outreach and news

Articles

Article: RHEUMATOLOGY. 2024;:keae146

Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis-a prospective cohort study

Circiumaru A; Kisten Y; Hansson M; Mathsson-Alm L; Joshua V; Waehaemaa H; Loberg Haarhaus M; Lindqvist J; Padyukov L; Catrina S-B; Fei G; Vivar N; Rezaei H; af Klint E; Antovic A; Rethi B; Catrina AI; Hensvold A
Article: BIOMOLECULES. 2023;13(4):630

Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation

Circiumaru A; Afonso MG; Wahamaa H; Krishnamurthy A; Hansson M; Mathsson-Alm L; Keszei M; Stalesen R; Ottosson L; de Vries C; Shelef MA; Malmstrom V; Klareskog L; Catrina AI; Gronwall C; Hensvold A; Rethi B
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(2):164-170

Combination of Two Monoclonal Anti-Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase-4-Dependent Manner

Krishnamurthy A; Circiumaru A; Sun J; Kisten Y; Damberg P; Sakuraba K; Sandor K; Jarvoll P; Zhou T; Malmstrom V; Svensson CI; Hensvold A; Catrina AI; Klareskog L; Rethi B
Article: FRONTIERS IN MEDICINE. 2022;9:774945

Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study

Knevel R; Knitza J; Hensvold A; Circiumaru A; Bruce T; Evans S; Maarseveen T; Maurits M; Beaart-van de Voorde L; Simon D; Kleyer A; Johannesson M; Schett G; Huizinga T; Svanteson S; Lindfors A; Klareskog L; Catrina A
Article: RMD OPEN. 2021;7(2):e001662

Tocilizumab decreases T cells but not macrophages in the synovium of patients with rheumatoid arthritis while it increases the levels of serum interleukin-6 and RANKL

Chatzidionysiou K; Circiumaru A; Rethi B; Joshua V; Engstrom M; Hensvold A; af Klint E; Catrina A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts

Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Gronwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wahamaa H; Catrina AI

All other publications

Thesis / dissertation: 2024

From autoimmunity to inflamed joints : study of risk factors, mediators and cellular targets in rheumatoid arthritis

Cîrciumaru, Alexandra
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2020;79:569-570

DIVERSITY OF ANTI-CITRULLINATED PROTEIN ANTIBODY COMPOSITIONS INFLUENCE SYNOVIAL FIBROBLAST REACTIVITY

Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Engstrom M; Gronwall C; Malmstrom V; Amara K; Klareskog L; Wahamaa H; Catrina A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2020;79:934-935

METABOLIC CHANGES INDUCED BY ANTI-MALONDIALDEHYDE/MALINDIALDEHYDE-ACETALDEHYDE ANTIBODIES PROMOTE OSTEOCLAST DEVELOPMENT

Sakuraba K; Krishnamurthy A; Circiumaru A; Sun M; Joshua V; Engstrom M; Zheng X; Xu C; Amara K; Malmstrom V; Catrina SB; Gronwall C; Rethi B; Catrina A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2020;79:1247

SPECIFIC ACPA REACTIVITIES AND INFLAMMATORY BIOMARKERS ALONG WITH ULTRASOUND TENOSYNOVITIS ARE ASSOCIATED WITH ARTHRITIS ONSET IN A POPULATION AT RISK FOR RHEUMATOID ARTHRITIS

Circiumaru A; Kisten Y; Hansson M; Joshua V; Sun M; Rezaei H; Af Klint E; Antovic A; Catrina A; Hensvold A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:957

HUMAN MONOCLONAL ACPAS INDUCE MOBILITY OF PRIMED SYNOVIAL FIBROBLAST IN A PAD-DEPENDENT PATHWAY

Sun M; Krishnamurthy A; Circiumaru A; Engstrom M; Steen J; Titcombe P; Malmstrom V; Wahamaa H; Klareskog L; Rethi B; Catrina A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:954

IDENTIFICATION OF CELLULAR TARGETS FOR ANTI-CITRULLINATED PROTEIN ANTIBODIES (ACPAS)

Rethi B; Sun M; Circiumaru A; Krishnamurthy A; Wahamaa H; Ytterberg J; Malmstrom V; Klareskog L; Catrina A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:310

DEVELOPMENT OF ULTRASOUND DETECTABLE ARTHRITIS AMONG ACPA POSITIVE SUBJECTS WITH MUSCULOSKELETAL SYMPTOMS: THE RISK RA PROSPECTIVE STUDY

Hensvold A; Kisten Y; Circiumaru A; Hansson M; Sun M; Fei G; Vivar N; Af Klint E; Rezaei H; Klareskog L; Antovic A; Catrina A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:1090-1091

INVESTIGATING MECHANISMS OF AUTOANTIBODY INDUCED PAIN, BONE LOSS AND ARTHRITIS DEVELOPMENT

Krishnamurthy A; Kisten Y; Sandor K; Circiumaru A; Wigerblad G; Damberg P; Sakurabas K; Wahamaa H; Jarvolli P; Jimenez Andrade JJ; Malmstrom V; Klareskog L; Svensson C; Rethi B; Catrina A
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:A75

POTENTIAL ROLE FOR THE CHEMOKINE CCL22 IN THE DEVELOPMENT AND EARLY PROGRESSION OF RHEUMATOID ARTHRITIS

Rethi B; Krishnamurthy A; Circiumaru A; Sakurabas K; Joshua V; Sun M; Szu-Ying C; Engstrom M; Wahamaa H; Hensvold A; Smith JE; Catrina AI
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2019;78:A8-A9

TENOSYNOVITIS AND HLA-SE PREDICT ARTHRITIS ONSET IN ACPA-POSITIVE INDIVIDUALS AT RISK OF DEVELOPING RHEUMATOID ARTHRITIS

Hensvold AH; Kisten Y; Hansson M; Circiumaru A; Sun M; Fei G; Af Klint E; Rezaei H; Antovic A; Catrina AI
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2017;76:212

ROLES OF IL-8 IN RANK-L- AND ACPA-MEDIATED OSTEOCLASTOGENESIS

Circiumaru A; Liu Y; Krishnamurthy A; Mia SM; Joshua V; Engstrom M; Malmstrom V; Sun M; Wahamaa H; Rethi B; Catrina A

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2024-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2024

Articles

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Employments

Degrees and Education

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