Albin Björk

Publications
CV
Public outreach and news

Selected publications

Review: NATURE REVIEWS RHEUMATOLOGY. 2023;19(5):288-306
Genetics and epigenetics of primary Sjogren syndrome: implications for future therapies
Thorlacius GE; Bjork A; Wahren-Herlenius M

Articles

Journal article: RHEUMATOLOGY. 2025
Anti-mitochondrial antibodies as markers of disease activity in childhood-onset systemic lupus erythematosus: a longitudinal cohort study
Macêdo MB; Wahadat MJ; Björk A; Kamphuis S; Versnel MA; Lood C
Article: RMD OPEN. 2025;11(2):e005351
Amlexanox inhibits production of type I interferon and suppresses B cell differentiation in vitro: a possible therapeutic option for systemic lupus erythematosus and other systemic inflammatory diseases
Bjork A; Wahadat MJ; Sanchez-Blazquez M; Braams M; Rip J; van Tilburg SJ; van Helden-Meeuwsen CG; Kamphuis S; van den Bosch TPP; Brkic Z; Versnel MA
Article: JOURNAL OF AUTOIMMUNITY. 2025;154:103434
Microbial dysbiosis fuels STING-driven autoinflammation through cyclic dinucleotides
Shibahara T; Temizoz B; Egashira S; Hosomi K; Park J; Surucu N; Bjork A; Sag E; Doi T; Ekinci RMK; Balci S; Versnel MA; Kunisawa J; Yamamoto M; Hayashi T; Ito S; Kamiyama Y; Kobiyama K; Katsikis PD; Coban C; Gursel M; Ozen S; Nishida S; Kumanogoh A; Ishii KJ
Article: ARTHRITIS RESEARCH & THERAPY. 2025;27(1):49
Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation
Juto A; Martin M; Bjork A; Padyukov L; Gronwall C; Antovic A; Bruchfeld A; Gunnarsson I; Blom AM
Article: RHEUMATOLOGY. 2024;:keae693
A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren's disease
Fugmann C; Reid S; Pucholt P; Kvarnstrom M; Bjork A; Mofors J; Sjowall C; Eriksson P; Olsson P; Mandl T; Forsblad-d'Elia H; Magnusson Bucher S; Johnsen SJ; Norheim KB; Appel S; Hammenfors D; Jensen JL; Palm O; Omdal R; Jonsson R; Baecklund E; Wahren-Herlenius M; Leonard D; Imgenberg-Kreuz J; Nordmark G
Article: RHEUMATOLOGY. 2021;60(3):1445-1455
Interferon activation status underlies higher antibody response to viral antigens in patients with systemic lupus erythematosus receiving no or light treatment
Bjork A; Rodrigues RDS; Andersson ER; Sepulveda JIR; Mofors J; Kvarnstrom M; Oke V; Svenungsson E; Gunnarsson I; Wahren-Herlenius M
Article: RHEUMATOLOGY. 2021;60(2):837-848
Genetic and clinical basis for two distinct subtypes of primary Sjogren's syndrome
Thorlacius GE; Hultin-Rosenberg L; Sandling JK; Bianchi M; Imgenberg-Kreuz J; Pucholt P; Theander E; Kvarnstrom M; Forsblad-d'Elia H; Bucher SM; Norheim KB; Johnsen SJA; Hammenfors D; Skarstein K; Jonsson MV; Baecklund E; Aqrawi LA; Jensen JL; Palm O; Morris AP; Meadows JRS; Rantapaa-Dahlqvist S; Mandl T; Eriksson P; Lind L; Omdal R; Jonsson R; Lindblad-Toh K; Ronnblom L; Wahren-Herlenius M; Nordmark G
Article: RMD OPEN. 2020;6(3):e001402
Cigarette smoking patterns preceding primary Sjogren's syndrome
Mofors J; Bjork A; Richardsdotter Andersson E; Kvarnstrom M; Forsblad D'Elia H; Magnusson-Bucher S; Padyukov L; Kockum I; Hillert J; Eriksson P; Mandl T; Nordmark G; Alfredsson L; Wahren-Herlenius M
Article: RHEUMATOLOGY. 2020;59(7):1651-1661
Viral antigens elicit augmented immune responses in primary Sjogren's syndrome
Bjork A; Thorlacius GE; Mofors J; Andersson ER; Ivanchenko M; Tingstrom J; James T; Brokstad KA; Cox RJ; Jonsson R; Kvarnstrom M; Wahren-Herlenius M
Article: RMD OPEN. 2020;6(1):e000995
Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjogren's syndrome
Bjork A; Andersson ER; Imgenberg-Kreuz J; Thorlacius GE; Mofors J; Syvanen A-C; Kvarnstrom M; Nordmark G; Wahren-Herlenius M
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:580547
Single-Stranded Oligonucleotide-Mediated Inhibition of Respiratory Syncytial Virus Infection
Palsson SA; Dondalska A; Bergenstrahle J; Rolfes C; Bjork A; Sedano L; Power UF; Rameix-Welti M-A; Lundeberg J; Wahren-Herlenius M; Mastrangelo P; Eleouet J-F; Le Goffic R; Galloux M; Spetz A-L
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:582737
Plasma C4d Correlates With C4d Deposition in Kidneys and With Treatment Response in Lupus Nephritis Patients
Martin M; Trattner R; Nilsson SC; Bjork A; Zickert A; Blom AM; Gunnarsson I
Article: BIOLOGY OF SEX DIFFERENCES. 2019;10(1):60
Sex differences in clinical presentation of systemic lupus erythematosus
Sepulveda JIR; Bolin K; Mofors J; Leonard D; Svenungsson E; Jonsen A; Bengtsson C; Nordmark G; Dahlqvist SR; Bengtsson AA; Ronnblom L; Sjowall C; Gunnarsson I; Wahren-Herlenius M; Zickert A; Bjork A; Jonsen A; Sjowali C; Enocsson H; Wettero J; Eriksson P; Thorlacius GE; Lundberg IE; Sanding JK; SeNiveda JIR; Lindblad-Toh K; Ronnblom L; Padyukov L; Hultin-Rosenberg L; Eloranta M-L; Dahiqvist SR
Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(4):458-468
Concomitant Ro/SSA and La/SSB antibodies are biomarkers for the risk of venous thromboembolism and cerebral infarction in primary Sjogren's syndrome
Mofors J; Holmqvist M; Westermark L; Bjork A; Kvarnstrom M; Forsblad-d'Elia H; Bucher SM; Eriksson P; Theander E; Mandl T; Wahren-Herlenius M; Nordmark G
Article: JOURNAL OF INTERNAL MEDICINE. 2019;285(6):670-680
Infections increase the risk of developing Sjogren's syndrome
Mofors J; Arkema EV; Bjork A; Westermark L; Kvarnstrom M; Forsblad-d'Elia H; Bucher SM; Eriksson P; Mandl T; Nordmark G; Wahren-Herlenius M
Article: ELIFE. 2019;8:e41608
In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta
Pernemalm M; Sandberg A; Zhu Y; Boekel J; Tamburro D; Schwenk JM; Bjork A; Wahren-Herlenius M; Amark H; Ostenson C-G; Westgren M; Lehtio J
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;192(3):259-270
Diminished CXCR5 expression in peripheral blood of patients with Sjogren's syndrome may relate to both genotype and salivary gland homing
Aqrawi LA; Ivanchenko M; Bjork A; Sepulveda JIR; Imgenberg-Kreuz J; Kvarnstrom M; Haselmayer P; Jensen JL; Nordmark G; Chemin K; Skarstein K; Wahren-Herlenius M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2018;87(5):e12662
Transcription profiling of peripheral B cells in antibody-positive primary Sjogren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature
Imgenberg-Kreuz J; Sandling JK; Bjork A; Nordlund J; Kvarnstrom M; Eloranta M-L; Ronnblom L; Wahren-Herlenius M; Syvanen A-C; Nordmark G
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1939
Early Resistance of Non-virulent Mycobacterial Infection in C57BL/6 Mice Is Associated With Rapid Up-Regulation of Antimicrobial Cathelicidin Camp
Adam L; Lopez-Gonzalez M; Bjork A; Palsson S; Poux C; Wahren-Herlenius M; Fernandez C; Spetz A-L
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):266
Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus.
Martin M; Smoląg KI; Björk A; Gullstrand B; Okrój M; Leffler J; Jönsen A; Bengtsson AA; Blom AM
Article: CELL DEATH AND DIFFERENTIATION. 2016;23(5):903-911
Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes.
Martin M; Leffler J; Smoląg KI; Mytych J; Björk A; Chaves LD; Alexander JJ; Quigg RJ; Blom AM
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All other publications

Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2024;83:42-43
OP0179 DISEASE ASSOCIATED AUTOANTIBODIES ARE LINKED TO GRADUAL PROTEOMIC CHANGES IN PRIMARY SJÖGREN’S SYNDROME
Björk A; Mofors J; Meneghel L; Kvarnström M; Jonsson R; Omdal R; Forsblad-D’elia H; Bucher SM; Eriksson P; Mandl T; Olsson P; Imgenberg-Kreuz J; Nordmark G; Wahren-Herlenius M
Preprint: BIORXIV. 2023;BIORXIV
Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland.
Wiley MM; Khatri B; Joachims ML; Tessneer KL; Stolarczyk AM; Rasmussen A; Anaya J-M; Aqrawi LA; Bae S-C; Baecklund E; Björk A; Brun JG; Bucher SM; Dand N; Eloranta M-L; Engelke F; Forsblad-d'Elia H; Fugmann C; Glenn SB; Gong C; Gottenberg J-E; Hammenfors D; Imgenberg-Kreuz J; Jensen JL; Johnsen SJA; Jonsson MV; Kelly JA; Khanam S; Kim K; Kvarnström M; Mandl T; Martín J; Morris DL; Nocturne G; Norheim KB; Olsson P; Palm Ø; Pers J-O; Rhodus NL; Sjöwall C; Skarstein K; Taylor KE; Tombleson P; Thorlacius GE; Venuturupalli S; Vital EM; Wallace DJ; Grundahl KM; Radfar L; Brennan MT; James JA; Scofield RH; Gaffney PM; Criswell LA; Jonsson R; Appel S; Eriksson P; Bowman SJ; Omdal R; Rönnblom L; Warner BM; Rischmueller M; Witte T; Farris AD; Mariette X; Shiboski CH; Sjögren’s International Collaborative Clinical All; Wahren-Herlenius M; Alarcón-Riquelme ME; PRECISESADS Clinical Consortium; Ng W-F; UK Primary Sjögren’s Syndrome Registry; Sivils KL; Guthridge JM; Adrianto I; Vyse TJ; Tsao BP; Nordmark G; Lessard CJ
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:1068
AMLEXANOX INHIBITS PRODUCTION OF TYPE I INTERFERON AND SUPPRESSES B CELL DIFFERENTIATION AND IMMUNOGLOBULIN PRODUCTION IN VITRO: A POTENTIAL NOVEL THERAPEUTIC OPTION FOR SLE
Bjork A; Wahadat MJ; Braams M; Van Helden-Meeuwsen CG; Versnel M
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:705
SEX-EQTL ANALYSIS REVEALS A SIGNIFICANT SEXBIAS IN THE EFFECTS OF SJOGREN'S SYNDROME ASSOCIATED ALLELES ON GENE TRANSCRIPTION
Thorlacius GE; Bjork A; Wahren-Herlenius M
Review: RHEUMATOLOGY. 2021;60(6):2561-2573
Innate immunity and interferons in the pathogenesis of Sjogren's syndrome
Bodewes ILA; Bjork A; Versnel MA; Wahren-Herlenius M
Book chapter: OXFORD TEXTBOOK OF SJÖGREN'S SYNDROME. 2021;p. 33-44
Autoantibodies and autoantigens in Sjögren’s syndrome
Ambrosi A; Björk A; Wahren-Herlenius M
Doctoral thesis: 2021
Immunopathogenic mechanisms in primary Sjögren’s syndrome
Björk A
Corrigendum: RHEUMATOLOGY. 2021;60(3):1575
Interferon activation status underlies higher antibody response to viral antigens in patients with systemic lupus erythematosus receiving no or light treatment (vol 60, pg 1445, 2021)
Bjork A; Rodrigues RDS; Andersson ER; Sepulveda JIR; Mofors J; Kvarnstrom M; Oke V; Svenungsson E; Gunnarsson I; Wahren-Herlenius M
Review: JOURNAL OF INTERNAL MEDICINE. 2020;287(5):475-492
Environmental factors in the pathogenesis of primary Sjogren's syndrome
Bjork A; Mofors J; Wahren-Herlenius M
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(2):307-308
Increased risk of multiple myeloma in primary Sjogren's syndrome is limited to individuals with Ro/SSA and La/SSB autoantibodies
Mofors J; Bjoerk A; Smedby KE; Kvarnstrom M; Forsblad-d'Elia H; Magnusson-Bucher S; Eriksson P; Mandl T; Baecklund E; Nordmark G; Wahren-Herlenius M
Letter: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2019;195(3):305-309
FoxP3⁺CXCR5⁺CD4⁺ T cell frequencies are increased in peripheral blood of patients with primary Sjogren's syndrome
Ivanchenko M; Aqrawi LA; Bjork A; Wahren-Herlenius M; Chemin K
Conference publication: MOLECULAR IMMUNOLOGY. 2019;114:416-417
PLASMA C4d CORRELATES WITH C4d DEPOSITION IN KIDNEYS AND WITH TREATMENT RESPONSE IN SYSTEMIC LUPUS ERYTHEMATOSUS
Martin M; Nilsson SC; Bjork A; Gunnarsson I; Blom AM
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(12):1840-1842
Clinical associations and expression pattern of the autoimmunity susceptibility factor DIORA-1 in patients with primary Sjogren's syndrome
Aqrawi LA; Mentlein L; Meneghel L; Bjork A; Thorlacius GE; Ivanchenko M; Sepulveda JIR; Skarstein K; Kvarnstrom M; Brauner S; Espinosa A; Wahren-Herlenius M
Meeting abstract: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2018;36(3):S331-S332
Primary Sjogren's syndrome increases the risk of cardiovascular events, with the highest risk in SSA/SSB autoantibody positive patients
Mofors J; Westermark L; Bjork A; Kvarnstrom M; Forsblad-d'Elia H; Bucher SM; Eriksson P; Mandl T; Wahren-Herlenius M; Nordmark G
Meeting abstract: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2018;36(3):S330
Cigarette smoking is a risk factor for developing primary Sjogren's syndrome with Ro/SSA and La/SSB autoantibodies
Bjork A; Mofors J; Kvarnstrom M; Forsblad-d'Elia H; Bucher SM; Hillert J; Eriksson P; Mandl T; Nordmark G; Alfredsson L; Wahren-Herlenius M
Meeting abstract: ARTHRITIS & RHEUMATOLOGY. 2016;68
Expression of the Chemokine Receptor CXCR5 Is Decreased in the Periphery of Patients with Primary Sjogren's Syndrome
Wahren-Herlenius M; Aqrawi LA; Ivanchenko M; Bjork A; Ramirez J; Kvarnstrom M; Jensen JCL; Skarstein K

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2021

Selected publications

Articles

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Employments

Degrees and Education

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