Alberto Joven Araus

Alberto Joven Araus

Research Specialist
Visiting address: Solnavägen 9, 17165 Stockholm
Postal address: C5 Cell- och molekylärbiologi, C5 CMB Simon, 171 77 Stockholm
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About me

  • I have developed my scientific experience in the fields of Neuroscience, Developmental Biology and Regeneration, mainly using newts as animal model. My social and meticulous nature, together with an ambitious professional attitude, have led me to be part of a number of groundbreaking projects, in which we innovate and contribute to the continuous development of scientific knowledge, applying cutting-edge techniques to this animal model.

    My goal is to continue advancing the basic knowledge of complex tissue regeneration that occurs naturally in newts. This will pave the way towards translational approaches that will accelerate the development of new regenerative therapies for humans.

Research

  • Some of the milestones I have achieved in András Simon's lab have been the implementation of molecular methods to the Iberian ribbed newt (Pleurodeles waltl), the generation of genetically modified newts, and the study of their internal tissues using non-invasive research imaging techniques (ultrasound, micro-computed tomography and magnetic resonance imaging). Our group was also a pioneer in the sequencing and assembly of the large genome and transcriptome of Pleurodeles, as well as in the implementation of next generation sequencing (Next Generation Sequencing) in this species (single-cell RNA sequencing and spatially-resolved transcriptomics).

    Taken together, these advances have been fundamental in positioning Pleurodeles as an internationally emerging model organism in cellular, molecular and genetic biology studies in the fields of neuroscience, tissue development and regeneration with an innovative, multidisciplinary and collaborative approach.

Teaching

  • I contribute to teaching at Karolinska Institutet since 2015. For my professional development and adequacy, I have completed the web course for supervisors of Karolinska Insitutet and the course “Teaching and Learning in Higher Education Distance (GHPD)”.

    My teaching activities have included:
    • Cytoskeleton, ECM, Adhesion, Genetics in Health and Disease discussions for the Medicine program (2015-2018: 49 hours).
    • Laboratory practical in Basic Cell biology (2017, 13 hours).
    • Embryology and molecular signalling lectures for the Biomedicine program (2015-2023: 68 hours).
    • Main supervisor of 3 projects from 2 undergrad students of the Master in Biomedicine:
    • Junior Research Project: Role and cell dynamics of macrophages during salamander limb regeneration (6 weeks, full-time).
    • Master thesis: Innate immune response in salamanders during homeostasis, induced sickness behavior and regeneration (20 weeks, full-time).
    • Junior Research Project: Establishment of pharmacological depletion methodology of microglia and macrophages in the Salamander brain (6 weeks, full-time).
    • Main supervisor of 1 ERASMUS+ trainee internship (project as part of his Master's degree program in Molecular Biotechnology):
    • Methods development for subtype-specific neuronal tracing in salamanders (14 weeks, full-time).
    • Co-supervisor of 2 PhD students:
    • https://openarchive.ki.se/xmlui/handle/10616/46157
    • https://openarchive.ki.se/xmlui/handle/10616/48882

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