Aisha Siddiqah Ahmed

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Articles

Journal article: OSTEOARTHRITIS AND CARTILAGE OPEN. 2025;7(1):100543
Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis
Naili JE; Ahmed AS; Hedstrom M; Simonsen MB; Brostrom EW; Harris HE; Vegvari A; Aulin C
Article: PAIN. 2024;165(7):e65-e79
Unraveling the neuroimmune interface in chronic pain-the association between cytokines in the cerebrospinal fluid and pain in patients with lumbar disk herniation or degenerative disk disease
Rosenstrom AHC; Ahmed AS; Kultima K; Freyhult E; Berg S; Farinotti AB; Palada V; Svensson CI; Kosek E
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:S479-S480
BIOFUNC: IDENTIFYING OSTEOARTHRITIS-SPECIFIC PROTEINS ASSOCIATED WITH OBJECTIVELY EVALUATED PERFORMANCE-BASED JOINT FUNCTION AND PATIENT REPORTED PAIN
Naili J; Hedstrom M; Ahmed AS; Simonsen MB; Brostrom EW; Harris H; Vegvari A; Aulin C
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:S482-S483
INTEGRATIVE ANALYSIS OF MENISCI TISSUE IDENTIFIES PROTEASOME AS A REGULATOR FOR DEGENERATIVE CHANGES IN KNEE OSTEOARTHRITIS
Wu X; Hamzatova A; Aulin C; Struglics A; Ackermann P; Ahmed AS
Article: ARCHIVES OF REHABILITATION RESEARCH AND CLINICAL TRANSLATION. 2023;5(4):100297
The Effect of Group Training or Spinal Orthosis on Quality of Life and Potential Plasma Markers of Pain in Older Women With Osteoporosis. A Randomized Controlled Trial
Uzunel E; Kronhed A-CG; Alin CK; Ahmed AS; Wandell P; Salminen H
Journal article: GAIT AND POSTURE. 2023;106:s53-s54
Objectively evaluated joint function and patient-reported pain are associated with differences in the proteomic landscape of knee osteoarthritis
Naili JE; Hedström M; Ahmed A; Simonsen MB; Broström EW; Harris HE; Vegvari A; Aulin C
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(5):128
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson CI; Yuan J; Hart DA; Ahmed AS; Ackermann PW
Article: BIOMOLECULES. 2023;13(2):342
Identification of Lipid Biomarkers for Chronic Joint Pain Associated with Different Joint Diseases
Khoury S; Colas J; Breuil V; Kosek E; Ahmed AS; Svensson CI; Marchand F; Deval E; Ferreira T
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1191536
Network proteomic analysis identifies inter-alpha-trypsin inhibitor heavy chain 4 during early human Achilles tendon healing as a prognostic biomarker of good long-term outcomes
Wu X; Chen J; Sun W; Hart DA; Ackermann PW; Ahmed AS
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1225957
Complement factor D regulates collagen type I expression and fibroblast migration to enhance human tendon repair and healing outcomes
Chen J; Wang J; Hart DA; Zhou Z; Ackermann PW; Ahmed AS
Article: PAIN. 2022;163(10):1999-2013
Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Jacquot F; Khoury S; Labrum B; Delanoe K; Pidoux L; Barbier J; Delay L; Bayle A; Aissouni Y; Barriere DA; Kultima K; Freyhult E; Hugo A; Kosek E; Ahmed AS; Jurczak A; Lingueglia E; Svensson CI; Breuil V; Ferreira T; Marchand F; Deval E
Article: THE FASEB JOURNAL. 2022;36(6):e22365
Complement factor D as a predictor of Achilles tendon healing and long-term patient outcomes
Chen J; Wang J; Hart DA; Ahmed AS; Ackermann PW
Article: RHEUMATOLOGY. 2021;60(4):1724-1733
Expression of mitochondrial TSPO and FAM173B is associated with inflammation and symptoms in patients with painful knee osteoarthritis
Palada V; Ahmed AS; Hugo A; Radojcic MR; Svensson CI; Kosek E
Article: JOURNAL OF EXPERIMENTAL ORTHOPAEDICS. 2021;8(1):20
FGF gene expression in injured tendons as a prognostic biomarker of 1-year patient outcome after Achilles tendon repair
Chen J; Svensson J; Sundberg C-J; Ahmed AS; Ackermann PW
Article: JOURNAL OF NEUROIMMUNOLOGY. 2020;349:577391
Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity
Palada V; Ahmed AS; Freyhult E; Hugo A; Kultima K; Svensson CI; Kosek E
Journal article: 2019;22(4):16895-16904
Differential Expressions of Nerve Fibers During Distraction Osteogenesis - A Study in Rat Model
Li J; Ahmed AS; Zachrisson P; Nannmark U; Mark H; Stark A; Ahmed M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(3):E658-658
NF-B-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease
Ahmed AS; Berg S; Alkass K; Druid H; Hart DA; Svensson CI; Kosek E
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2019;75:60-71
Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease
Palada V; Ahmed AS; Finn A; Berg S; Svensson CI; Kosek E
Article: JOURNAL OF IMMUNOLOGY. 2018;201(7):1918-1927
Activation of NF-κB in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression
Ahmed AS; Gedin P; Hugo A; Bakalkin G; Kanar A; Hart DA; Druid H; Svensson C; Kosek E
Article: JOURNAL OF NEUROIMMUNOLOGY. 2018;321:49-60
Differences in neuroimmune signalling between male and female patients suffering from knee osteoarthritis
Kosek E; Finn A; Ultenius C; Hugo A; Svensson C; Ahmed AS
Article: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES. 2017;20(1):25-32
Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis
Ahmed AS; Ahmed M; Li J; Gu HF; Bakalkin G; Stark A; Harris HE
Article: PLOS ONE. 2017;12(1):e0170748
Compromised Neurotrophic and Angiogenic Regenerative Capability during Tendon Healing in a Rat Model of Type-II Diabetes
Ahmed AS; Li J; Abdul AMD; Ahmed M; Ostenson C-G; Salo PT; Hewitt C; Hart DA; Ackermann PW
Journal article: OPEN JOURNAL OF RHEUMATOLOGY AND AUTOIMMUNE DISEASES. 2016;06(02):26-33
Synovial Neuronal Changes in Knee Joint Osteoarthritis
aq N; Masood U; Shahryar N; Bo CB; Jian L; Aisha SA; Mahmood A
Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2016;920:179-184
Does Diabetes Mellitus Affect Tendon Healing?
Ahmed AS
Article: CELL AND TISSUE RESEARCH. 2014;357(1):109-117
Expressional changes in growth and inflammatory mediators during Achilles tendon repair in diabetic rats: new insights into a possible basis for compromised healing
Ahmed AS; Li J; Schizas N; Ahmed M; Ostenson C-G; Salo P; Hewitt C; Hart DA; Ackermann PW
Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2013;333:e524
Control of chronic pain by the ubiquitin proteasome system
Yakovleva T; Ossipov MH; Ahmed AS; Bakalkin G
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2012;113(11):1784-1791
Type 2 diabetes impairs tendon repair after injury in a rat model
Ahmed AS; Schizas N; Li J; Ahmed M; Ostenson C-G; Salo P; Hewitt C; Hart DA; Ackermann PW
Article: OPEN JOURNAL OF RHEUMATOLOGY AND AUTOIMMUNE DISEASES. 2012;2012(03):64-72
Validation of Reference Genes for mRNA Quantification in Adjuvant Arthritis
Alam QMA; Siddiqah AA; Jian L; André S; Per E; Mahmood A
Article: PAIN. 2012;153(1):18-26
Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis
Ahmed AS; Li J; Erlandsson-Harris H; Stark A; Bakalkin G; Ahmed M
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):2160-2169
Attenuation of Pain and Inflammation in Adjuvant-Induced Arthritis by the Proteasome Inhibitor MG132
Ahmed AS; Li J; Ahmed M; Hua L; Yakovleva T; Ossipov MH; Bakalkin G; Stark A
Article: THE FASEB JOURNAL. 2006;20(12):2124-2126
Prodynorphin storage and processing in axon terminals and dendrites
Yakovleva T; Bazov I; Cebers G; Marinova Z; Hara Y; Ahmed A; Vlaskovska M; Johansson BR; Hochgeschwender U; Singh IN; Bruce-Keller AJ; Hurd YL; Kaneko T; Terenius L; Ekstrom TJ; Hauser KF; Pickel VM; Bakalkin G
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All other publications

Review: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2024;12:1357871
Optimizing tendon repair and regeneration: how does the in vivo environment shape outcomes following rupture of a tendon such as the Achilles tendon?
Hart DA; Ahmed AS; Chen J; Ackermann PW
Preprint: RESEARCH SQUARE. 2023
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson CI; Yuan J; Hart DA; Ahmed AS; Ackermann PW
Preprint: BIORXIV. 2022
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson C; Yuan J; Hart D; Ahmed A; Ackermann P
Review: FRONTIERS IN SPORTS AND ACTIVE LIVING. 2022;4:1081129
Optimizing repair of tendon ruptures and chronic tendinopathies: Integrating the use of biomarkers with biological interventions to improve patient outcomes and clinical trial design
Hart DA; Ahmed AS; Ackermann P
Preprint: BIORXIV. 2021
Lysophosphatidyl-choline 16:0 mediates persistent joint pain through Acid-Sensing Ion Channel 3: preclinical and clinical evidences
Jacquot F; Khoury S; Labrum B; Delanoe K; Pidoux L; Barbier J; Delay L; Bayle A; Aissouni Y; Barriere D; Kultima K; Freyhult E; Hugo A; Kosek E; Ahmed A; Jurczak A; Lingueglia E; Svensson C; Breuil V; Ferreira T; Marchand F; Deval E
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:21
PROTEASOME AS A THERAPEUTIC TARGET IN OSTEOARTHRITIS?
Ahmed A
Book chapter: RHEUMATOID ARTHRITIS TREATMENT. 2012;p.
Proteasome targeted therapies in rheumatoid arthritis. Rheumatoid Arthritis
Ahmed AS
Thesis / dissertation: 2010
Proteasome targeted therapy in arthritis models : effects on pain and inflammation
Ahmed, Aisha Siddiqah

Grants

Identifiering, validering och mekanistisk analys av biomarkör för smärta vid knäartros
Identification, validation, and mechanistic analysis of biomarker of pain in Osteoarthritis
Prognostic Biomarkers of Patient Outcome after Achilles Tendon Rupture (ATR)
The Swedish Research Council for Sport Science

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2023
Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2010

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