Aisha Siddiqah Ahmed

Publications
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Articles

Journal article: PAIN. 2024;165(7):e65-e79
Unraveling the neuroimmune interface in chronic pain-the association between cytokines in the cerebrospinal fluid and pain in patients with lumbar disk herniation or degenerative disk disease
Rosenstrom AHC; Ahmed AS; Kultima K; Freyhult E; Berg S; Farinotti AB; Palada V; Svensson CI; Kosek E
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:s479-s480
BIOFUNC: IDENTIFYING OSTEOARTHRITIS-SPECIFIC PROTEINS ASSOCIATED WITH OBJECTIVELY EVALUATED PERFORMANCE-BASED JOINT FUNCTION AND PATIENT REPORTED PAIN
Naili J; Hedstrom M; Ahmed AS; Simonsen MB; Brostrom EW; Harris H; Vegvari A; Aulin C
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:s482-s483
INTEGRATIVE ANALYSIS OF MENISCI TISSUE IDENTIFIES PROTEASOME AS A REGULATOR FOR DEGENERATIVE CHANGES IN KNEE OSTEOARTHRITIS
Wu X; Hamzatova A; Aulin C; Struglics A; Ackermann P; Ahmed AS
Article: ARCHIVES OF REHABILITATION RESEARCH AND CLINICAL TRANSLATION. 2023;5(4):100297
The Effect of Group Training or Spinal Orthosis on Quality of Life and Potential Plasma Markers of Pain in Older Women With Osteoporosis. A Randomized Controlled Trial
Uzunel E; Kronhed A-CG; Alin CK; Ahmed AS; Wandell P; Salminen H
Journal article: GAIT & POSTURE. 2023;106:S53-S54
Objectively evaluated joint function and patient-reported pain are associated with differences in the proteomic landscape of knee osteoarthritis
Naili JE; Hedström M; Ahmed A; Simonsen MB; Broström EW; Harris HE; Vegvari A; Aulin C
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(5):128
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson CI; Yuan J; Hart DA; Ahmed AS; Ackermann PW
Article: BIOMOLECULES. 2023;13(2):342
Identification of Lipid Biomarkers for Chronic Joint Pain Associated with Different Joint Diseases
Khoury S; Colas J; Breuil V; Kosek E; Ahmed AS; Svensson CI; Marchand F; Deval E; Ferreira T
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1191536
Network proteomic analysis identifies inter-alpha-trypsin inhibitor heavy chain 4 during early human Achilles tendon healing as a prognostic biomarker of good long-term outcomes
Wu X; Chen J; Sun W; Hart DA; Ackermann PW; Ahmed AS
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1225957
Complement factor D regulates collagen type I expression and fibroblast migration to enhance human tendon repair and healing outcomes
Chen J; Wang J; Hart DA; Zhou Z; Ackermann PW; Ahmed AS
Article: PAIN. 2022;163(10):1999-2013
Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Jacquot F; Khoury S; Labrum B; Delanoe K; Pidoux L; Barbier J; Delay L; Bayle A; Aissouni Y; Barriere DA; Kultima K; Freyhult E; Hugo A; Kosek E; Ahmed AS; Jurczak A; Lingueglia E; Svensson CI; Breuil V; Ferreira T; Marchand F; Deval E
Article: FASEB JOURNAL. 2022;36(6):e22365
Complement factor D as a predictor of Achilles tendon healing and long-term patient outcomes
Chen J; Wang J; Hart DA; Ahmed AS; Ackermann PW
Article: RHEUMATOLOGY. 2021;60(4):1724-1733
Expression of mitochondrial TSPO and FAM173B is associated with inflammation and symptoms in patients with painful knee osteoarthritis
Palada V; Ahmed AS; Hugo A; Radojcic MR; Svensson CI; Kosek E
Article: JOURNAL OF EXPERIMENTAL ORTHOPAEDICS. 2021;8(1):20
FGF gene expression in injured tendons as a prognostic biomarker of 1-year patient outcome after Achilles tendon repair
Chen J; Svensson J; Sundberg C-J; Ahmed AS; Ackermann PW
Article: JOURNAL OF NEUROIMMUNOLOGY. 2020;349:577391
Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity
Palada V; Ahmed AS; Freyhult E; Hugo A; Kultima K; Svensson CI; Kosek E
Journal article: 2019;22(4):16895-16904
Differential Expressions of Nerve Fibers During Distraction Osteogenesis - A Study in Rat Model
Li J; Ahmed AS; Zachrisson P; Nannmark U; Mark H; Stark A; Ahmed M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(3):E658-658
NF-B-Associated Pain-Related Neuropeptide Expression in Patients with Degenerative Disc Disease
Ahmed AS; Berg S; Alkass K; Druid H; Hart DA; Svensson CI; Kosek E
Article: BRAIN BEHAVIOR AND IMMUNITY. 2019;75:60-71
Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease
Palada V; Ahmed AS; Finn A; Berg S; Svensson CI; Kosek E
Article: JOURNAL OF IMMUNOLOGY. 2018;201(7):1918-1927
Activation of NF-κB in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression
Ahmed AS; Gedin P; Hugo A; Bakalkin G; Kanar A; Hart DA; Druid H; Svensson C; Kosek E
Article: JOURNAL OF NEUROIMMUNOLOGY. 2018;321:49-60
Differences in neuroimmune signalling between male and female patients suffering from knee osteoarthritis
Kosek E; Finn A; Ultenius C; Hugo A; Svensson C; Ahmed AS
Article: PLOS ONE. 2017;12(1):e0170748
Compromised Neurotrophic and Angiogenic Regenerative Capability during Tendon Healing in a Rat Model of Type-II Diabetes
Ahmed AS; Li J; Abdul AMD; Ahmed M; Ostenson C-G; Salo PT; Hewitt C; Hart DA; Ackermann PW
Article: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES. 2017;20(1):25-32
Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis
Ahmed AS; Ahmed M; Li J; Gu HF; Bakalkin G; Stark A; Harris HE
Article: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2016;920:179-184
Does Diabetes Mellitus Affect Tendon Healing?
Ahmed AS
Journal article: OPEN JOURNAL OF RHEUMATOLOGY AND AUTOIMMUNE DISEASES. 2016;06(02):26-33
Synovial Neuronal Changes in Knee Joint Osteoarthritis
aq N; Masood U; Shahryar N; Bo CB; Jian L; Aisha SA; Mahmood A
Article: CELL AND TISSUE RESEARCH. 2014;357(1):109-117
Expressional changes in growth and inflammatory mediators during Achilles tendon repair in diabetic rats: new insights into a possible basis for compromised healing
Ahmed AS; Li J; Schizas N; Ahmed M; Ostenson C-G; Salo P; Hewitt C; Hart DA; Ackermann PW
Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2013;333:e524
Control of chronic pain by the ubiquitin proteasome system
Yakovleva T; Ossipov MH; Ahmed AS; Bakalkin G
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2012;113(11):1784-1791
Type 2 diabetes impairs tendon repair after injury in a rat model
Ahmed AS; Schizas N; Li J; Ahmed M; Ostenson C-G; Salo P; Hewitt C; Hart DA; Ackermann PW
Article: OPEN JOURNAL OF RHEUMATOLOGY AND AUTOIMMUNE DISEASES. 2012;2012(03):64-72
Validation of Reference Genes for mRNA Quantification in Adjuvant Arthritis
Alam QMA; Siddiqah AA; Jian L; André S; Per E; Mahmood A
Article: PAIN. 2012;153(1):18-26
Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis
Ahmed AS; Li J; Erlandsson-Harris H; Stark A; Bakalkin G; Ahmed M
Article: ARTHRITIS & RHEUMATOLOGY. 2010;62(7):2160-2169
Attenuation of Pain and Inflammation in Adjuvant-Induced Arthritis by the Proteasome Inhibitor MG132
Ahmed AS; Li J; Ahmed M; Hua L; Yakovleva T; Ossipov MH; Bakalkin G; Stark A
Article: FASEB JOURNAL. 2006;20(12):2124-2126
Prodynorphin storage and processing in axon terminals and dendrites
Yakovleva T; Bazov I; Cebers G; Marinova Z; Hara Y; Ahmed A; Vlaskovska M; Johansson BR; Hochgeschwender U; Singh IN; Bruce-Keller AJ; Hurd YL; Kaneko T; Terenius L; Ekstrom TJ; Hauser KF; Pickel VM; Bakalkin G
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All other publications

Review: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2024;12:1357871
Optimizing tendon repair and regeneration: how does the in vivo environment shape outcomes following rupture of a tendon such as the Achilles tendon?
Hart DA; Ahmed AS; Chen J; Ackermann PW
Preprint: RESEARCH SQUARE. 2023
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson CI; Yuan J; Hart DA; Ahmed AS; Ackermann PW
Preprint: BIORXIV. 2022
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson C; Yuan J; Hart D; Ahmed A; Ackermann P
Review: FRONTIERS IN SPORTS AND ACTIVE LIVING. 2022;4:1081129
Optimizing repair of tendon ruptures and chronic tendinopathies: Integrating the use of biomarkers with biological interventions to improve patient outcomes and clinical trial design
Hart DA; Ahmed AS; Ackermann P
Preprint: BIORXIV. 2021
Lysophosphatidyl-choline 16:0 mediates persistent joint pain through Acid-Sensing Ion Channel 3: preclinical and clinical evidences
Jacquot F; Khoury S; Labrum B; Delanoe K; Pidoux L; Barbier J; Delay L; Bayle A; Aissouni Y; Barriere D; Kultima K; Freyhult E; Hugo A; Kosek E; Ahmed A; Jurczak A; Lingueglia E; Svensson C; Breuil V; Ferreira T; Marchand F; Deval E
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:21
PROTEASOME AS A THERAPEUTIC TARGET IN OSTEOARTHRITIS?
Ahmed A
Book chapter: RHEUMATOID ARTHRITIS TREATMENT. 2012;p.
Proteasome targeted therapies in rheumatoid arthritis. Rheumatoid Arthritis
Ahmed AS
Thesis / dissertation: 2010
Proteasome targeted therapy in arthritis models : effects on pain and inflammation
Ahmed, Aisha Siddiqah

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2023
Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2010

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