Aisha Siddiqah Ahmed

Publications
Grants
CV
Public outreach and news

Articles

Article: BRAIN, BEHAVIOR, & IMMUNITY - HEALTH. 2026;53:101227
Distinct serum and cerebrospinal fluid metabolic signatures associate with pain and fatigue in knee osteoarthritis
Bjerkhaug AU; Jakobsson JE; Ahmed AS; Carlsson H; Erngren I; Al-Grety A; Farinotti AB; Svensson CI; Kultima K; Kosek E
Article: FASEB BIOADVANCES. 2026;8(5):e70101
Network Analysis Identifies Microsomal Glutathione S-Transferase as a Potential Regulator of Oxidative Stress and Proteasome Dysfunction in Human Osteoarthritic Menisci
Wu X; Hamzatova A; Aulin C; Sun W; Struglics A; Hart DA; Ackermann PW; Ahmed AS
Article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 2026;:1-11
Acute responses of inflammatory markers, glucose, and myoglobin in blood following neuromuscular electrical stimulation
Flodin J; Amiri P; Reitzner SM; Ahmed AS; Ackermann PW
Article: BRAIN BEHAVIOR AND IMMUNITY. 2025;128:54-64
CCL25 in the cerebrospinal fluid is negatively correlated with fatigue in chronic pain patients
Rosenstrom AHC; Ahmed AS; Farinotti AB; Kultima K; Berg S; Bjurstrom MF; Svensson CI; Kosek E
Article: PHYSIOLOGICAL GENOMICS. 2025;57(6):391-402
The acute effects of neuromuscular electrical stimulation on coagulation and cardiovascular factors
Flodin J; Reitzner SM; Soutari NMH; Ahmed AS; Guo L; Persson N-K; Antovic JP; Ackermann PW
Article: OSTEOARTHRITIS AND CARTILAGE OPEN. 2025;7(1):100543
Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis
Naili JE; Ahmed AS; Hedstrom M; Simonsen MB; Brostrom EW; Harris HE; Vegvari A; Aulin C
Article: SCIENTIFIC REPORTS. 2025;15(1):7318
Novel tissue biomarker candidates to predict both deep venous thrombosis and healing outcome after Achilles tendon rupture
Saarensilta A; Chen J; Reitzner SM; Hart DA; Ahmed AS; Ackermann PW
Article: PAIN. 2024;165(7):e65-e79
Unraveling the neuroimmune interface in chronic pain-the association between cytokines in the cerebrospinal fluid and pain in patients with lumbar disk herniation or degenerative disk disease
Rosenstrom AHC; Ahmed AS; Kultima K; Freyhult E; Berg S; Farinotti AB; Palada V; Svensson CI; Kosek E
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:s479-s480
BIOFUNC: IDENTIFYING OSTEOARTHRITIS-SPECIFIC PROTEINS ASSOCIATED WITH OBJECTIVELY EVALUATED PERFORMANCE-BASED JOINT FUNCTION AND PATIENT REPORTED PAIN
Naili J; Hedstrom M; Ahmed AS; Simonsen MB; Brostrom EW; Harris H; Vegvari A; Aulin C
Journal article: OSTEOARTHRITIS AND CARTILAGE. 2024;32:s482-s483
INTEGRATIVE ANALYSIS OF MENISCI TISSUE IDENTIFIES PROTEASOME AS A REGULATOR FOR DEGENERATIVE CHANGES IN KNEE OSTEOARTHRITIS
Wu X; Hamzatova A; Aulin C; Struglics A; Ackermann P; Ahmed AS
Article: ARCHIVES OF REHABILITATION RESEARCH AND CLINICAL TRANSLATION. 2023;5(4):100297
The Effect of Group Training or Spinal Orthosis on Quality of Life and Potential Plasma Markers of Pain in Older Women With Osteoporosis. A Randomized Controlled Trial
Uzunel E; Kronhed A-CG; Alin CK; Ahmed AS; Wandell P; Salminen H
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1225957
Complement factor D regulates collagen type I expression and fibroblast migration to enhance human tendon repair and healing outcomes
Chen J; Wang J; Hart DA; Zhou Z; Ackermann PW; Ahmed AS
Journal article: GAIT & POSTURE. 2023;106:s53-s54
Objectively evaluated joint function and patient-reported pain are associated with differences in the proteomic landscape of knee osteoarthritis
Naili JE; Hedström M; Ahmed A; Simonsen MB; Broström EW; Harris HE; Vegvari A; Aulin C
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1191536
Network proteomic analysis identifies inter-alpha-trypsin inhibitor heavy chain 4 during early human Achilles tendon healing as a prognostic biomarker of good long-term outcomes
Wu X; Chen J; Sun W; Hart DA; Ackermann PW; Ahmed AS
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2023;80(5):128
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson CI; Yuan J; Hart DA; Ahmed AS; Ackermann PW
Article: BIOMOLECULES. 2023;13(2):342
Identification of Lipid Biomarkers for Chronic Joint Pain Associated with Different Joint Diseases
Khoury S; Colas J; Breuil V; Kosek E; Ahmed AS; Svensson CI; Marchand F; Deval E; Ferreira T
Article: PAIN. 2022;163(10):1999-2013
Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Jacquot F; Khoury S; Labrum B; Delanoe K; Pidoux L; Barbier J; Delay L; Bayle A; Aissouni Y; Barriere DA; Kultima K; Freyhult E; Hugo A; Kosek E; Ahmed AS; Jurczak A; Lingueglia E; Svensson CI; Breuil V; Ferreira T; Marchand F; Deval E
Article: FASEB JOURNAL. 2022;36(6):e22365
Complement factor D as a predictor of Achilles tendon healing and long-term patient outcomes
Chen J; Wang J; Hart DA; Ahmed AS; Ackermann PW
Article: RHEUMATOLOGY. 2021;60(4):1724-1733
Expression of mitochondrial TSPO and FAM173B is associated with inflammation and symptoms in patients with painful knee osteoarthritis
Palada V; Ahmed AS; Hugo A; Radojcic MR; Svensson CI; Kosek E
Article: JOURNAL OF EXPERIMENTAL ORTHOPAEDICS. 2021;8(1):20
FGF gene expression in injured tendons as a prognostic biomarker of 1-year patient outcome after Achilles tendon repair
Chen J; Svensson J; Sundberg C-J; Ahmed AS; Ackermann PW
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All other publications

Preprint: RESEARCH SQUARE. 2026
A SP1-Driven Translational-Proteostatic Checkpoint Modulates the Autophagy-Proteasome Network
Ahmed A; Chen J; Hamzatova A; Zhang Y; Fu X; Souza D; Yuan J; Chen X; Hart D; Zeng W; Zhou Z
Review: ADVANCES IN WOUND CARE. 2026;15(4):246-263
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions
Chen J; Fu X; Ahmed AS; Hart DA; Zhou Z; Ackermann PW
Book chapter: TENDON REGENERATION. 2025;p. 181-218
Chapter 5 Medical considerations in tendinopathy
Ackermann PW; Ahmed AS; Hart DA
Review: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 2024;12:1357871
Optimizing tendon repair and regeneration: how does the in vivo environment shape outcomes following rupture of a tendon such as the Achilles tendon?
Hart DA; Ahmed AS; Chen J; Ackermann PW
Preprint: RESEARCH SQUARE. 2023
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson CI; Yuan J; Hart DA; Ahmed AS; Ackermann PW
Review: FRONTIERS IN SPORTS AND ACTIVE LIVING. 2023;4:1081129
Optimizing repair of tendon ruptures and chronic tendinopathies: Integrating the use of biomarkers with biological interventions to improve patient outcomes and clinical trial design
Hart DA; Ahmed AS; Ackermann P
Preprint: BIORXIV. 2022
eEF2 improves dense connective tissue repair and healing outcome by regulating cellular death, autophagy, apoptosis, proliferation and migration
Chen J; Wang J; Wu X; Simon N; Svensson C; Yuan J; Hart D; Ahmed A; Ackermann P
Preprint: BIORXIV. 2021
Lysophosphatidyl-choline 16:0 mediates persistent joint pain through Acid-Sensing Ion Channel 3: preclinical and clinical evidences
Jacquot F; Khoury S; Labrum B; Delanoe K; Pidoux L; Barbier J; Delay L; Bayle A; Aissouni Y; Barriere D; Kultima K; Freyhult E; Hugo A; Kosek E; Ahmed A; Jurczak A; Lingueglia E; Svensson C; Breuil V; Ferreira T; Marchand F; Deval E
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:21
PROTEASOME AS A THERAPEUTIC TARGET IN OSTEOARTHRITIS?
Ahmed A
Book chapter: RHEUMATOID ARTHRITIS TREATMENT. 2012;p.
Proteasome targeted therapies in rheumatoid arthritis. Rheumatoid Arthritis
Ahmed AS
Doctoral thesis: 2010
Proteasome targeted therapy in arthritis models : effects on pain and inflammation
Ahmed AS

Grants

Identification, validation, and mechanistic analysis of biomarker of pain in Osteoarthritis
Ulla Hamberg Angeby och Lennart Angebys stiftelse
Prognostic Biomarkers of Patient Outcome after Achilles Tendon Rupture (ATR)
The Swedish Research Council for Sport Science
Proteomic profile of chronic pain in knee osteoarthritis and development of proteasome targeted therapies
Swedish Rheumatism Association

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2026-2029

Degrees and Education

Docent, Karolinska Institutet, 2023
Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2010

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