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Selected publications from OnkPat

OnkPat publications with Impact factor 8 and higher:


Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death
S. Busker, W. Qian, M. Haraldsson, B. Espinosa, L. Johansson, S. Attarha, et al
Sci Adv 2020 Mar; 6(12)

AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma.
Das I, Gad H, Bräutigam L, Pudelko L, Tuominen R, Höiom V, et al
Cell Death Differ. 2020 Jan;():

PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.
Rykaczewska U, Suur BE, Röhl S, Razuvaev A, Lengquist M, Sabater-Lleal M, et al
Circ. Res. 2020 Jan;():

Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy.
Rudd SG, Tsesmetzis N, Sanjiv K, Paulin CB, Sandhow L, Kutzner J, et al
EMBO Mol Med 2020 Jan;():e10419

CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.
Neo SY, Yang Y, Record J, Ma R, Chen X, Chen Z, et al
J. Clin. Invest. 2020 Feb;():

MAIT Cells in Health and Disease.
Magalhaes I, Solders M, Kaipe H
Methods Mol. Biol. 2020 ;2098():3-21


Double Immunohistochemistry and Digital Image Analysis.
Moreno-Ruiz P, Wik Leiss L, Mezheyeuski A, Ehnman M
Methods Mol. Biol. 2019 ;1913():3-11

Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Chromium Release Assay.
van der Haar Àvila I, Marmol P, Kiessling R, Pico de Coaña Y
Methods Mol. Biol. 2019 ;1913():167-179

Computational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell Lines.
Rees MG, Seashore-Ludlow B, Clemons PA
Methods Mol. Biol. 2019 ;1888():233-254

Establishment of Melanoma Tumor Xenograft Using Single Cell Line Suspension and Co-injection of Patient-Derived T Cells in Immune-Deficient NSG Mice.
Gunnarsdóttir FB, Kiessling R, Pico de Coaña Y
Methods Mol. Biol. 2019 ;1913():207-215

Evaluation of Breast Cancer and Melanoma Metastasis in Syngeneic Mouse Models.
Witt K, Lundqvist A
Methods Mol. Biol. 2019 ;1913():197-206

Evaluating Antibody-Dependent Cell-Mediated Cytotoxicity by Flow Cytometry.
van der Haar Àvila I, Marmol P, Cany J, Kiessling R, Pico de Coaña Y
Methods Mol. Biol. 2019 ;1913():181-194

Immune Monitoring of Cancer Patients by Multi-color Flow Cytometry.
Neo SY, O'Reilly A, Pico de Coaña Y
Methods Mol. Biol. 2019 ;1913():49-65

Strategies and Techniques for NK Cell Phenotyping.
Ziqing C, Lundqvist A, Witt K
Methods Mol. Biol. 2019 ;2032():105-114

Somatic Structural Alterations in Childhood Leukemia Can Be Backtracked in Neonatal Dried Blood Spots by Use of Whole-Genome Sequencing and Digital PCR.
Taylan F, Bang B, Öfverholm II, Tran AN, Heyman M, Barbany G, et al
Clin. Chem. 2019 02;65(2):345-347

Assessment of Antitumor T-Cell Responses by Flow Cytometry After Coculture of Tumor Cells with Autologous Tumor-Infiltrating Lymphocytes.
Melief J, Wickström S, Kiessling R, Pico de Coaña Y
Methods Mol. Biol. 2019 ;1913():133-140

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis.
Smith HW, Hirukawa A, Sanguin-Gendreau V, Nandi I, Dufour CR, Zuo D, et al
Nat Commun 2019 07;10(1):2901

PrimPol is required for the maintenance of efficient nuclear and mitochondrial DNA replication in human cells.
Bailey LJ, Bianchi J, Doherty AJ
Nucleic Acids Res. 2019 05;47(8):4026-4038

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.
Lorent J, Kusnadi EP, van Hoef V, Rebello RJ, Leibovitch M, Ristau J, et al
EMBO J. 2019 12;38(23):e101323

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate.
Sica V, Bravo-San Pedro JM, Izzo V, Pol J, Pierredon S, Enot D, et al
Cell Rep 2019 04;27(3):820-834.e9

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples.
Zhang X, Garnerone S, Simonetti M, Harbers L, Nicoś M, Mirzazadeh R, et al
Nat Commun 2019 10;10(1):4732

Definition of Synchronous Oligometastatic Non-Small Cell Lung Cancer-A Consensus Report.
Dingemans AC, Hendriks LEL, Berghmans T, Levy A, Hasan B, Faivre-Finn C, et al
J Thorac Oncol 2019 Dec;14(12):2109-2119

Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response.
Johnson JL, Stoica L, Liu Y, Zhu PJ, Bhattacharya A, Buffington SA, et al
Neuron 2019 Nov;104(4):665-679.e8

Reduced-dose combination chemotherapy (S-1 plus oxaliplatin) versus full-dose monotherapy (S-1) in older vulnerable patients with metastatic colorectal cancer (NORDIC9): a randomised, open-label phase 2 trial.
Winther SB, Liposits G, Skuladottir H, Hofsli E, Shah CH, Poulsen LØ, et al
Lancet Gastroenterol Hepatol 2019 May;4(5):376-388

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma.
Chan K, Robert F, Oertlin C, Kapeller-Libermann D, Avizonis D, Gutierrez J, et al
Nat Commun 2019 11;10(1):5151

Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML.
Karjalainen R, Liu M, Kumar A, He L, Malani D, Parsons A, et al
Leukemia 2019 10;33(10):2548-2553

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.
Lorent J, Kusnadi EP, van Hoef V, Rebello RJ, Leibovitch M, Ristau J, et al
EMBO J. 2019 12;38(23):e101323

2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial.
Utjés D, Malmstedt J, Teras J, Drzewiecki K, Gullestad HP, Ingvar C, et al
Lancet 2019 08;394(10197):471-477

Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer.
Yu NY, Iftimi A, Yau C, Tobin NP, van 't Veer L, Hoadley KA, et al
JAMA Oncol 2019 Aug;():

Decrypting noncoding RNA interactions, structures, and functional networks.
Fabbri M, Girnita L, Varani G, Calin GA
Genome Res. 2019 09;29(9):1377-1388

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.
Costa TDF, Zhuang T, Lorent J, Turco E, Olofsson H, Masia-Balague M, et al
Nat Commun 2019 08;10(1):3589

Outcome and Presentation of Heart Failure in Breast Cancer Patients; Findings from a Swedish register-based study.
Hedayati E, Papakonstantinou A, Gernaat SAM, Altena R, Brand JS, Alfredsson J, et al
Eur Heart J Qual Care Clin Outcomes 2019 Jul;():

The viral protein corona directs viral pathogenesis and amyloid aggregation.
Ezzat K, Pernemalm M, Pålsson S, Roberts TC, Järver P, Dondalska A, et al
Nat Commun 2019 05;10(1):2331

ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer.
Kuninty PR, Bansal R, De Geus SWL, Mardhian DF, Schnittert J, van Baarlen J, et al
Sci Adv 2019 Sep;5(9):eaax2770

Prognostic implications of PD-L1 expression in breast cancer: systematic review and meta-analysis of immunohistochemistry and pooled analysis of transcriptomic data.
Matikas A, Zerdes I, Lövrot J, Richard F, Sotiriou C, Bergh J, et al
Clin. Cancer Res. 2019 Jun;():

Breast cancer quantitative proteome and proteogenomic landscape.
Johansson HJ, Socciarelli F, Vacanti NM, Haugen MH, Zhu Y, Siavelis I, et al
Nat Commun 2019 04;10(1):1600

Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia.
Yang M, Vesterlund M, Siavelis I, Moura-Castro LH, Castor A, Fioretos T, et al
Nat Commun 2019 04;10(1):1519

Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery.
Yu R, Jin SB, Lendahl U, Nistér M, Zhao J
EMBO J. 2019 Apr;38(8):

Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
Strell C, Paulsson J, Jin SB, Tobin NP, Mezheyeuski A, Roswall P, et al
J. Natl. Cancer Inst. 2019 Feb;():

A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer.
Sjöberg E, Meyrath M, Milde L, Herrera M, Lövrot J, Hägerstrand D, et al
Clin. Cancer Res. 2019 Mar;():

Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials.

Lancet 2019 Apr;393(10179):1440-1452

Utility of Gonadotropin-Releasing Hormone Agonists for Fertility Preservation: Lack of Biologic Basis and the Need to Prioritize Proven Methods.
Turan V, Bedoschi G, Rodriguez-Wallberg K, Sonmezer M, Pacheco FS, Oktem O, et al
J. Clin. Oncol. 2019 Jan;37(1):84-86

Dose tailoring of adjuvant chemotherapy for breast cancer based on hematologic toxicities: further results from the prospective PANTHER study with focus on obese patients.
Matikas A, Foukakis T, Moebus V, Greil R, Bengtsson NO, Steger GG, et al
Ann. Oncol. 2019 Jan;30(1):109-114

Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes.
Binzer-Panchal A, Hardell E, Viklund B, Ghaderi M, Bosse T, Nucci MR, et al
Clin. Cancer Res. 2019 Apr;25(7):2155-2165

SubCellBarCode: Proteome-wide Mapping of Protein Localization and Relocalization.
Orre LM, Vesterlund M, Pan Y, Arslan T, Zhu Y, Fernandez Woodbridge A, et al
Mol. Cell 2019 Jan;73(1):166-182.e7

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.
Dziekan JM, Yu H, Chen D, Dai L, Wirjanata G, Larsson A, et al
Sci Transl Med 2019 Jan;11(473):

Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma.
Indira Chandran V, Welinder C, Månsson AS, Offer S, Freyhult E, Pernemalm M, et al
Clin. Cancer Res. 2019 May;25(10):3115-3127

Updated results from the phase 3 HELIOS study of ibrutinib, bendamustine, and rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma.
Fraser G, Cramer P, Demirkan F, Silva RS, Grosicki S, Pristupa A, et al
Leukemia 2019 04;33(4):969-980

A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration.
Coelho JPL, Stahl M, Bloemeke N, Meighen-Berger K, Alvira CP, Zhang ZR, et al
Nat Commun 2019 02;10(1):672

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.
Prakash V, Carson BB, Feenstra JM, Dass RA, Sekyrova P, Hoshino A, et al
Nat Commun 2019 05;10(1):2110

TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer.
De Laere B, Oeyen S, Mayrhofer M, Whitington T, van Dam PJ, Van Oyen P, et al
Clin. Cancer Res. 2019 Mar;25(6):1766-1773

Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.
Morita M, Siddiqui N, Katsumura S, Rouya C, Larsson O, Nagashima T, et al
Proc. Natl. Acad. Sci. U.S.A. 2019 Apr;116(16):7973-7981

Fam83F induces p53 stabilisation and promotes its activity.
Salama M, Benitez-Riquelme D, Elabd S, Munoz L, Zhang P, Glanemann M, et al
Cell Death Differ. 2019 Oct;26(10):2125-2138

Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL.
Hohtari H, Brück O, Blom S, Turkki R, Sinisalo M, Kovanen PE, et al
Leukemia 2019 Jul;33(7):1570-1582

Phosphorylation of G3BP1-S149 does not influence stress granule assembly.
Panas MD, Kedersha N, Schulte T, Branca RM, Ivanov P, Anderson P
J. Cell Biol. 2019 Jul;218(7):2425-2432

EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance.
Li S, Rodriguez J, Li W, Bullova P, Fell SM, Surova O, et al
Proc. Natl. Acad. Sci. U.S.A. 2019 Aug;116(34):16997-17006

Anagrelide for Gastrointestinal Stromal Tumor.
Pulkka OP, Gebreyohannes YK, Wozniak A, Mpindi JP, Tynninen O, Icay K, et al
Clin. Cancer Res. 2019 Mar;25(5):1676-1687

Early-Stage NSCLC: Advances in Thoracic Oncology 2018.
Osarogiagbon RU, Veronesi G, Fang W, Ekman S, Suda K, Aerts JG, et al
J Thorac Oncol 2019 Jun;14(6):968-978

Generally applicable transcriptome-wide analysis of translation using anota2seq.
Oertlin C, Lorent J, Murie C, Furic L, Topisirovic I, Larsson O
Nucleic Acids Res. 2019 Jul;47(12):e70

The Case Against the European Medicines Agency's Change to the Label for Radium-223 for the Treatment of Metastatic Castration-resistant Prostate Cancer.
O'Sullivan JM, Heinrich D, James ND, Nilsson S, Ost P, Parker CC, et al
Eur. Urol. 2019 03;75(3):e51-e52

Multiplex Quantitative Analysis of Tumor-Infiltrating Lymphocytes and Immunotherapy Outcome in Metastatic Melanoma.
Wong PF, Wei W, Smithy JW, Acs B, Toki MI, Blenman KRM, et al
Clin. Cancer Res. 2019 Apr;25(8):2442-2449

Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL.
Xu-Monette ZY, Xiao M, Au Q, Padmanabhan R, Xu B, Hoe N, et al
Cancer Immunol Res 2019 Apr;7(4):644-657

Avoiding over- and undertreatment in patients with resected node-positive breast cancer with the use of gene expression signatures: are we there yet?
Matikas A, Foukakis T, Swain S, Bergh J
Ann. Oncol. 2019 Jul;30(7):1044-1050

Discontinuation of adjuvant hormone therapy among breast cancer patients not previously attending mammography screening.
He W, Eriksson L, Törnberg S, Strand F, Hall P, Czene K
BMC Med 2019 01;17(1):24

Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA.
Sun W, Dai L, Yu H, Puspita B, Zhao T, Li F, et al
Redox Biol 2019 Jun;24():101168

Implant Based Breast Reconstruction With Acellular Dermal Matrix: Safety Data From an Open-label, Multicenter, Randomized, Controlled Trial in the Setting of Breast Cancer Treatment.
Lohmander F, Lagergren J, Roy PG, Johansson H, Brandberg Y, Eriksen C, et al
Ann. Surg. 2019 May;269(5):836-841

Sperm count in Swedish clinical stage I testicular cancer patients following adjuvant treatment.
Weibring K, Nord C, Ståhl O, Eberhard J, Sandberg K, Johansson H, et al
Ann. Oncol. 2019 Apr;30(4):604-611

HER2: defining a Neu target in non-small-cell lung cancer.
Ekman S
Ann. Oncol. 2019 Mar;30(3):353-355

FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.
Turunen SP, von Nandelstadh P, Öhman T, Gucciardo E, Seashore-Ludlow B, Martins B, et al
Cell Death Differ. 2019 Mar;():

Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function.
Sandri BJ, Masvidal L, Murie C, Bartish M, Avdulov S, Higgins L, et al
Am. J. Respir. Crit. Care Med. 2019 Aug;200(3):348-358

Making immunotherapy 'cold' tumours 'hot' by chemotherapy-induced mutations-a misconception.
Helleday T
Ann. Oncol. 2019 Mar;30(3):360-361

Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial.
de Bono JS, Concin N, Hong DS, Thistlethwaite FC, Machiels JP, Arkenau HT, et al
Lancet Oncol. 2019 Mar;20(3):383-393

Amot and Yap1 regulate neuronal dendritic tree complexity and locomotor coordination in mice.
Rojek KO, Krzemień J, Doleżyczek H, Boguszewski PM, Kaczmarek L, Konopka W, et al
PLoS Biol. 2019 May;17(5):e3000253

Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA).
Dai L, Prabhu N, Yu LY, Bacanu S, Ramos AD, Nordlund P
Annu. Rev. Biochem. 2019 Jun;88():383-408

Previous years

Selected publications from 2018 OnkPat

Selected publications from 2017 OnkPat

Selected publications from 2016 OnkPat