Development / Stem Cells / Repair
Developmental neuroscientists study how neurons are generated from progenitor cells, how they divide, survive, and adopt specific identities, and migrate to sites where they are incorporated into neuronal circuits.
This knowledge is critical for further understanding of neurodevelopmental disorders, paediatric tumours in the nervous system, and certain psychiatric conditions such as autism.
Developmental neurobiology research is merging with that of the rapidly advancing stem cell field to provide an exciting platform for translational medicine aimed at developing reparative and regenerative treatment strategies for neurodegenerative disorders or traumatic injuries.
Group leaders and research areas
Ernest Arenas, Development and generation of dopamine neurons
Klas Blomgren, Injury and repair in the developing brain
Lou Brundin, Applied neuroscience and stem cells
Gonçalo Castelo-Branco, Epigenetic states during oligodendrocyte development
Sandra Ceccatelli, Developmental neurotoxicology
Staffan Cullheim, Synaptic plasticity and immune molecules
Johan Ericson, Neuronal fate determination in the developing CNS
Patrik Ernfors, Molecular neurobiology
Anna Falk, Induced pluripotent stem cells
Kaj Fried, Molecular determinants of tooth innervation
Jonas Frisén, Stem cells in tissue homeostasis and regenerative medicine
Tibor Harkany, Neurodevelopment, endocannabinoid signaling
Ola Hermanson, Neuronal development and differentiation
Jens Hjerling-Leffler, Genetics of adolescent brain development
Johan Holmberg, Neuronal differentiation and tumour formation
Carlos Ibáñez, Functions and signaling mechanisms of growth factors
François Lallemend, Sensory neuron specification and connectivity
Urban Lendahl, Notch signaling in development and disease
Jonas Muhr, Stem cell biology
Lars Olson, Regeneration, transplantation, Parkinson's disease
Thomas Perlmann, Molecular developmental biology and stem cells
Mårten Risling, Experimental traumatology
Gunnar Schulte, Receptor biology and signaling
András Simon, Regeneration mechanisms in an aquatic salamander
Kirsty Spalding, Cell regeneration in health, disease and aging
Peter Swoboda, Sorting and transport in C. elegans neurons
Cecilia Söderberg-Nauclér, Neural differentiation and cancer development
Per Uhlén, Intracellular signaling