Publications from Marie Arsenian Henriksson Group

Selected publications 2014-2020

p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids.
Marin Navarro A, Pronk RJ, van der Geest AT, Oliynyk G, Nordgren A, Arsenian-Henriksson M, et al
Cell Death Dis 2020 Jan;11(1):52

Integrative discovery of treatments for high-risk neuroblastoma.
Almstedt E, Elgendy R, Hekmati N, Rosén E, Wärn C, Olsen TK, et al
Nat Commun 2020 01;11(1):71

MYCN-enhanced Oxidative and Glycolytic Metabolism Reveals Vulnerabilities for Targeting Neuroblastoma.
Oliynyk G, Ruiz-Pérez MV, Sainero-Alcolado L, Dzieran J, Zirath H, Gallart-Ayala H, et al
iScience 2019 Nov;21():188-204

Serine-Glycine-One-Carbon Metabolism: The Hidden Achilles Heel of MYCN-Amplified Neuroblastoma?
Garcia AR, Arsenian-Henriksson M
Cancer Res. 2019 Aug;79(15):3818-3819

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells.
Tibbitt CA, Stark JM, Martens L, Ma J, Mold JE, Deswarte K, et al
Immunity 2019 07;51(1):169-184.e5

High-spatial-resolution x-ray fluorescence tomography with spectrally matched nanoparticles.
Larsson JC, Vogt C, Vågberg W, Toprak MS, Dzieran J, Arsenian-Henriksson M, et al
Phys Med Biol 2018 08;63(16):164001

Fibroblasts in the Tumor Microenvironment: Shield or Spear?
Alkasalias T, Moyano-Galceran L, Arsenian-Henriksson M, Lehti K
Int J Mol Sci 2018 May;19(5):

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, et al
Nat Commun 2018 03;9(1):1107

MYCN-amplified neuroblastoma maintains an aggressive and undifferentiated phenotype by deregulation of estrogen and NGF signaling.
Dzieran J, Rodriguez Garcia A, Westermark UK, Henley AB, Eyre Sánchez E, Träger C, et al
Proc. Natl. Acad. Sci. U.S.A. 2018 02;115(6):E1229-E1238

Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum.
Persson CU, von Stedingk K, Bexell D, Merselius M, Braekeveldt N, Gisselsson D, et al
Sci Rep 2017 08;7(1):10274

Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA.
Fell SM, Li S, Wallis K, Kock A, Surova O, Rraklli V, et al
Genes Dev. 2017 05;31(10):1036-1053

The MYCN Protein in Health and Disease.
Ruiz-Pérez MV, Henley AB, Arsenian-Henriksson M
Genes (Basel) 2017 Mar;8(4):

Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling.
Kramer M, Ribeiro D, Arsenian-Henriksson M, Deller T, Rohrer H
J. Neurosci. 2016 10;36(40):10425-10439

MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC.
Lohcharoenkal W, Harada M, Lovén J, Meisgen F, Landén NX, Zhang L, et al
J. Invest. Dermatol. 2016 12;136(12):2485-2494

Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients.
Ribeiro D, Klarqvist MDR, Westermark UK, Oliynyk G, Dzieran J, Kock A, et al
Cell Rep 2016 07;16(4):979-993

COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.
Larsson K, Kock A, Idborg H, Arsenian Henriksson M, Martinsson T, Johnsen JI, et al
Proc. Natl. Acad. Sci. U.S.A. 2015 Jun;112(26):8070-5

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.
Romeo MM, Ko B, Kim J, Brady R, Heatley HC, He J, et al
Virology 2015 Feb;476():271-288

TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity.
Stantic M, Sakil HA, Zirath H, Fang T, Sanz G, Fernandez-Woodbridge A, et al
Proc. Natl. Acad. Sci. U.S.A. 2015 Jan;112(1):220-5

Impact of MYC in regulation of tumor cell metabolism.
Wahlström T, Henriksson MA
Biochim. Biophys. Acta 2015 May;1849(5):563-9

X-ray phase contrast with injected gas for tumor microangiography.
Lundström U, Westermark UK, Larsson DH, Burvall A, Arsenian Henriksson M, Hertz HM
Phys Med Biol 2014 Jun;59(11):2801-11

MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division.
Zinin N, Adameyko I, Wilhelm M, Fritz N, Uhlén P, Ernfors P, et al
EMBO Rep. 2014 Apr;15(4):383-91

Book Chapters

Frenzel, A., and Arsenian Henriksson, M
MYC
Encyclopedia of Signalling Molecules, Springer Verlag. 2012
• Encyclopedia of Signalling Molecules