Klas Kärre Group - publications

Top publications from Klas Kärre group.

Picture of Klas Kärre lab



Iron and Ferritin Modulate MHC Class I Expression and NK Cell Recognition.
Sottile R, Federico G, Garofalo C, Tallerico R, Faniello MC, Quaresima B, et al
Front Immunol 2019 ;10():224

Accumulation of Circulating CCR7+ Natural Killer Cells Marks Melanoma Evolution and Reveals a CCL19-Dependent Metastatic Pathway.
Cristiani CM, Turdo A, Ventura V, Apuzzo T, Capone M, Madonna G, et al
Cancer Immunol Res 2019 05;7(5):841-852

2017 & 2018

Expression of CD226 is associated to but not required for NK cell education
Arnika K. Wagner, Nadir Kadri, Johanna Snäll, Petter Brodin, Susan Gilfillan, Marco Colonna, Günter Bernhardt, Petter Höglund, Klas Kärre & Benedict J. Chambers
Nature Communications 8, Article number: 15627 (2017) doi:10.1038/ncomms15627

IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients.
Tallerico R, Cristiani CM, Staaf E, Garofalo C, Sottile R, Capone M, et al
Oncoimmunology 2017 ;6(2):e1261242

George Klein (1925-2016).
Ernberg I, Kärre K, Wigzell H
Nature 2017 02;542(7641):296


Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells.
Luu TT, Ganesan S, Wagner AK, Sarhan D, Meinke S, Garbi N, et al
Sci Rep 2016 12;6():37996

Herpes simplex virus specific T cell response in a cohort with primary genital infection correlates inversely with frequency of subsequent recurrences.
Franzen-Röhl E, Schepis D, Atterfelt F, Franck K, Wikström A, Liljeqvist JÅ, et al
Sex Transm Infect 2017 05;93(3):169-174

IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo.
Kritikou JS, Dahlberg CI, Baptista MA, Wagner AK, Banerjee PP, Gwalani LA, et al
Sci Rep 2016 08;6():30636

In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation.
Lakshmikanth T, Heuts F, Muvva SS, Wallin RP, Persson AK, Fauriat C, et al
Eur J Immunol 2016 07;46(7):1758-69

Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.
Guldevall K, Brandt L, Forslund E, Olofsson K, Frisk TW, Olofsson PE, et al
Front Immunol 2016 ;7():119

Dynamic Regulation of NK Cell Responsiveness.
Kadri N, Wagner AK, Ganesan S, Kärre K, Wickström S, Johansson MH, et al
Curr Top Microbiol Immunol 2016 ;395():95-114


Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response.
Wagner AK, Wickström SL, Tallerico R, Salam S, Lakshmikanth T, Brauner H, et al
Cancer Immunol Res 2016 Feb;4(2):113-23

HLA class I downregulation is associated with enhanced NK-cell killing of melanoma cells with acquired drug resistance to BRAF inhibitors.
Sottile R, Pangigadde PN, Tan T, Anichini A, Sabbatino F, Trecroci F, et al
Eur J Immunol 2016 Feb;46(2):409-19

Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice.
Brauner H, Hall HT, Flodström-Tullberg M, Kärre K, Höglund P, Johansson S
Immunol Cell Biol 2016 Feb;94(2):177-84

Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients.
Ali TH, Pisanti S, Ciaglia E, Mortarini R, Anichini A, Garofalo C, et al
Nat Commun 2014 Dec;5():5639


A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells.
Wickström SL, Öberg L, Kärre K, Johansson MH
J Immunol 2014 Feb;192(4):1577-86


Natural killer cell inhibitory receptor expression in humans and mice: a closer look.
Sternberg-Simon M, Brodin P, Pickman Y, Onfelt B, Kärre K, Malmberg KJ, et al
Front Immunol 2013 ;4():65

Human NK cells selective targeting of colon cancer-initiating cells: a role for natural cytotoxicity receptors and MHC class I molecules.
Tallerico R, Todaro M, Di Franco S, Maccalli C, Garofalo C, Sottile R, et al
J Immunol 2013 Mar;190(5):2381-90


Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice.
Li Y, Kundu P, Seow SW, de Matos CT, Aronsson L, Chin KC, et al
Carcinogenesis 2012 Jun;33(6):1231-8

Expansion of T-cells from the cord blood graft as a predictive tool for complications and outcome of cord blood transplantation.
Gertow J, Berglund S, Okas M, Kärre K, Remberger M, Mattsson J, et al
Clin Immunol 2012 May;143(2):134-44

Skewing of the NK cell repertoire by MHC class I via quantitatively controlled enrichment and contraction of specific Ly49 subsets.
Brodin P, Lakshmikanth T, Kärre K, Höglund P
J Immunol 2012 Mar;188(5):2218-26

First International Meeting of the Thematic Centre for Immune Modulatory Therapies for Autoimmunity and Cancer (IMTAC) 13-14 June 2011, Ljusterö, Sweden.
Choudhury A, Höglund P, Kiessling R, Kärre K, Lundqvist A, Malmberg K, et al
Cancer Immunol Immunother 2012 Apr;61(4):587-91

Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules.
Dabrazhynetskaya A, Ma J, Guerreiro-Cacais AO, Arany Z, Rudd E, Henter JI, et al
J Cell Mol Med 2012 Jan;16(1):129-41

Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.
Li H, Lakshmikanth T, Garofalo C, Enge M, Spinnler C, Anichini A, et al
Cell Cycle 2011 Oct;10(19):3346-58

NK cell function and antibodies mediating ADCC in HIV-1-infected viremic and controller patients.
Johansson SE, Rollman E, Chung AW, Center RJ, Hejdeman B, Stratov I, et al
Viral Immunol 2011 Oct;24(5):359-68

Increased cell-mediated immune responses in patients with recurrent herpes simplex virus type 2 meningitis.
Franzen-Röhl E, Schepis D, Lagrelius M, Franck K, Jones P, Liljeqvist JÅ, et al
Clin Vaccine Immunol 2011 Apr;18(4):655-60

Content reviewer:
Sara Lidman