Kutter Group - Key publications

Key publications from the Kutter research group.

Keywords

Disease genomics and transcriptomics, gene regulation, mammalian noncoding RNA biology, RNA binding proteins, transcriptional control, transcriptome evolution, epitranscriptomics, cell plasticity, cell adaptation, organ development, metabolism, antiviral targeting, transposon control, CRISPR technology, NextGen sequencing

Publications

Target-enriched nanopore sequencing and de novo assembly reveals cooccurrences of complex on-target genomic rearrangements induced by CRISPR-Cas9 in human cells
Geng K, Merino LG, Wedemann L, Martens A, Sobota M, Sanchez YP, Søndergaard JN, White RJ, Kutter C
Genome Res. 2022 Sep 30

CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism.
Søndergaard JN, Sommerauer C, Atanasoai I, Hinte LC, Geng K, Guiducci G, Bräutigam L, Aouadi M, Stojic L, Barragan I, Kutter C
Gut 2022 Jan;():

Cell type-specific analysis by single-cell profiling identifies a stable mammalian tRNA-mRNA interface and increased translation efficiency in neurons.
Gao W, Gallardo-Dodd CJ, Kutter C
Genome Res 2022 Jan;32(1):97-110

Genome Size Reduction and Transposon Activity Impact tRNA Gene Diversity While Ensuring Translational Stability in Birds.
Ottenburghs J, Geng K, Suh A, Kutter C
Genome Biol Evol 2021 Apr;13(4):

Successful delivery of large-size CRISPR/Cas9 vectors in hard-to-transfect human cells using small plasmids.
Søndergaard JN, Geng K, Sommerauer C, Atanasoai I, Yin X, Kutter C
Commun Biol 2020 06;3(1):319

Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.
Rudolph KL, Schmitt BM, Villar D, White RJ, Marioni JC, Kutter C, et al
PLoS Genet. 2016 05;12(5):e1006024

High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA-tRNA interface.
Schmitt B, Rudolph K, Karagianni P, Fonseca N, White R, Talianidis I, et al
Genome Res. 2014 Nov;24(11):1797-807

The evolutionary landscape of alternative splicing in vertebrate species.
Barbosa-Morais NL, Irimia M, Pan Q, Xiong HY, Gueroussov S, Lee LJ, et al
Science 2012 Dec;338(6114):1587-93

Rapid turnover of long noncoding RNAs and the evolution of gene expression.
Kutter C, Watt S, Stefflova K, Wilson MD, Goncalves A, Ponting CP, et al
PLoS Genet. 2012 ;8(7):e1002841

Pol III binding in six mammals shows conservation among amino acid isotypes despite divergence among tRNA genes.
Kutter C, Brown GD, Gonçalves A, Wilson MD, Watt S, Brazma A, et al
Nat. Genet. 2011 Aug;43(10):948-55