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David Lane Group

The protein p53, widely known as the guardian of the genome, was discovered by Prof. Sir David Lane in 1979 and has over the years been recognized as a tumor suppressor gene mutated in more than half of all malignant tumors occurring in adults. Apart from its role as a tumor suppressor, p53 has been shown to be involved in numerous regulatory cell functions. Research in our lab is focused on understanding the many facets of p53 biology in malignant and normal cells. We employ cutting edge technology such as mass spectometry, advanced microscopy, multi-color flow cytometry and imaging cytometry to this end and strive to translate our findings to the clinic.

Projects within the David Lane Group

Principal Investigator Michael Landreh

Group Members

Cecilia BosdotterLaboratorietekniker

cecilia.bosdotter@ki.se

Nicolas FritzSenior forskningsspecialist

nicolas.fritz@ki.se

Katrine IngelshedDoktorand, Forskarstuderande

katrine.ingelshed@ki.se

Margit KaldmäePostdoc

margit.kaldmae@ki.se

Pavitra KannanPostdoc

pavitra.kannan@ki.se

Marcus LaddsPostdoc

marcus.ladds@ki.se

David LaneProfessor

david.lane@ki.se

Danai LianoudakiLaboratorietekniker

danai.lianoudaki@ki.se

Harsha MadapuraPostdoc

Harsha.Madapura@ki.se

Tanzina MollickDoktorand, Forskarstuderande

tanzina.mollick@ki.se

Cagla SahinPostdoc

cagla.sahin@ki.se

Chandra VermaAnknuten

chandra.verma@ki.se

Publications

30907951

30026328

30124469

29975538

29298430

28655792

28193768

1614522

218111

Further publications

All scientific publications from David Lane

Funding

The Swedish Research Council (Vetenskapsrådet)

Contact

David Lane Laboratory at Sci Life
Biomedicum quarter 7B-C Solnavägen 9, 17165 Solna
P53 Laboratory in Singapore
The p53 lab in singapore is focusing on the development of new therapies, new diagnostics and new discoveries in the p53 pathway.
More information on the website