David Lane Group
The protein p53, widely known as the guardian of the genome, was discovered by Prof. Sir David Lane in 1979 and has over the years been recognized as a tumor suppressor gene mutated in more than half of all malignant tumors occurring in adults. Apart from its role as a tumor suppressor, p53 has been shown to be involved in numerous regulatory cell functions. Research in our lab is focused on understanding the many facets of p53 biology in malignant and normal cells. We employ cutting edge technology such as mass spectometry, advanced microscopy, multi-color flow cytometry and imaging cytometry to this end and strive to translate our findings to the clinic.
Projects within the David Lane Group
|Nicolas Fritz||Senior forskningsspecialist|
|Katrine Ingelshed||Doktorand, Forskarstuderande|
|Tanzina Mollick||Doktorand, Forskarstuderande|
Biomedicum quarter 7B-C Solnavägen 9, 17165 Solna
The p53 lab in singapore is focusing on the development of new therapies, new diagnostics and new discoveries in the p53 pathway.
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