Selected publications from Malin Flodström-Tullberg group

Link to all publications (PubMed)

Selected publications

Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect.
Stone VM, Butrym M, Hankaniemi MM, Sioofy-Khojine AB, Hytönen VP, Hyöty H, Flodström-Tullberg M
Diabetes 2021 Sep;(): PMID: 34497136

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates.
Stone VM, Hankaniemi MM, Laitinen OH, Sioofy-Khojine AB, Lin A, Diaz Lozano IM, Mazur MA, Marjomäki V, Loré K, Hyöty H, Hytönen VP, Flodström-Tullberg M
Sci Adv 2020 May;6(19):eaaz2433 PMID: 32494709

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes.
Stone VM, Hankaniemi MM, Svedin E, Sioofy-Khojine A, Oikarinen S, Hyöty H, Laitinen OH, Hytönen VP, Flodström-Tullberg M
Diabetologia 2018 02;61(2):476-481 PMID29151123

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense.
Svedin E, Utorova R, Hühn MH, Larsson PG, Stone VM, Garimella M, Lind K, Hägglöf T, Pincikova T, Laitinen OH, McInerney GM, Scholte B, Hjelte L, Karlsson MCI, Flodström-Tullberg M
J Infect Dis 2017 12;216(10):1308-1317 PMID28968805

Coxsackievirus counters the host innate immune response by blocking type III interferon expression.
Lind K, Svedin E, Domsgen E, Kapell S, Laitinen OH, Moll M, Flodström-Tullberg M
J Gen Virol 2016 06;97(6):1368-1380 PMID: 26935471

A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.
Larsson PG, Lakshmikanth T, Laitinen OH, Utorova R, Jacobson S, Oikarinen M, Domsgen E, Koivunen MR, Chaux P, Devard N, Lecouturier V, Almond J, Knip M, Hyöty H, Flodström-Tullberg M
Diabetologia 2015 Feb;58(2):346-54 PMID25370797

Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets.
Lind K, Richardson SJ, Leete P, Morgan NG, Korsgren O, Flodström-Tullberg M
J Virol 2013 Jul;87(13):7646-54 PMID23637411

Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice.
Larsson PG, Lakshmikanth T, Svedin E, King C, Flodström-Tullberg M
Diabetologia 2013 Apr;56(4):867-74 PMID23344730

The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.
Hultcrantz M, Jacobson S, Hill NJ, Santamaria P, Flodström-Tullberg M
Diabetologia 2009 Feb;52(2):299-305 PMID19031069

Target cell defense prevents the development of diabetes after viral infection.
Flodström M, Maday A, Balakrishna D, Cleary MM, Yoshimura A, Sarvetnick N
Nat Immunol 2002 Apr;3(4):373-82 PMID11919579