Prognosis for ovarian cancer

Project description

We will study the effect of hormone-related etiological factors for ovarian cancer on tumour characteristics, and 5 and 10 years recidive-free survival. Study subjects are 917 women with ovarian cancer recruited in an earlier case-control study carried out between 1993-1995 in Sweden.

Our hypotheses are:

  • Null parity (Infertility), use of combined hormone contraceptive, use of hormone replacement therapy, high BMI (obesity) and late menopause are associated with early tumour stage, high tumour differentiation and endometrial epithelial cancer type.
  • These hormone-related exposures lead to a better prognosis, longer time recidive or death, and lower number of recidives / deaths within 5 years of diagnosis.
  • Tumor stage, grade of differentiation and histological subtype affect the survival of ovarian cancer patients.

Project leader

Professor

Elisabete Weiderpass Vainio

Telefon: 08-524 823 65
Enhet: C8.MEB.Weiderpass
E-post: Elisabete.Weiderpass.Vainio@ki.se

Project period: 1993 - Ongoing
Main financing: Karl V Jubilee Foundation, Cancerfonden

Partners

Name Role
Mats Lambe Professor
Rino Bellocco Associate professor
Pouran Almstedt Database manager

Publications

More about this study

More information about this study