Pregnancy-associated breast cancer (PABC)

Breast cancer during pregnancy represents a clinical dilemma. Because women tend to postpone childbearing to older age, the incidence of breast cancer coinciding with pregnancy is increasing.

Project description

Project goals/aims: To improve the understanding of pregnancy-associated breast cancer (PABC), defined as breast cancer during pregnancy or within two years following delivery.

Material: The Swedish National Cancer Register, six Regional Quality Registers on Breast Cancer, the Multi-Generational Register and other databases, medical records and tumour specimen.

Project leader

Mats Lambe

Telefon:08-524 861 64

Project period: 2010-2014
Main financing: The Susan G Komen Foundation for the Cure


Increasing incidence of pregnancy-associated breast cancer in Sweden.
Andersson T, Johansson A, Hsieh C, Cnattingius S, Lambe M
Obstet Gynecol 2009 Sep;114(3):568-72

Increased mortality in women with breast cancer detected during pregnancy and different periods postpartum.
Johansson A, Andersson T, Hsieh C, Cnattingius S, Lambe M
Cancer Epidemiol. Biomarkers Prev. 2011 Sep;20(9):1865-72

Stage at diagnosis and mortality in women with pregnancy-associated breast cancer (PABC).
Johansson AL, Andersson TM, Hsieh CC, Jirström K, Dickman P, Cnattingius S, et al
Breast Cancer Res. Treat. 2013 May;139(1):183-92