Academic achievement and risk of schizophrenia and bipolar disorder
The aim of this study is to examine good and poor school performance from the national Swedish school register, as risk factors for schizophrenia, bipolar disorder and other psychoses while controlling for pregnancy and birth complications and social factors.
Bipolar affective disorder and schizophrenia are severe psychiatric disorders of largely unknown aetiology, with a relatively abrupt onset of clinical symptoms in early adulthood. However, it is increasingly clear that subtle abnormalities may be detectable prior to the onset of symptoms, at least in schizophrenia.
Main financing: Medical Research Council, United Kingdom
Department of Psychological Medicine, Institute of Psychiatry and King's College, London: Robin M. Murray, James MacCabe, Pak Sham, Anthony David