We offer ultrasound-guided injections: rapid genetic manipulation in mouse (Infinigene).
Manipulation of gene expression during mouse development is a powerful tool for querying the role of specific genes in development and disease. Infinigene is a facility which utilizes ultrasound-guided nano-injection to introduce DNA-modifying agents during embryonic development, or in adult mice.
We can provide support during planning of in vivo injection experiments and assistance when applying for ethical permits. We offer support at different levels depending on the demands of the users.
- Ultrasound-guided injection of embryos/the amniotic sac with virus.
- Ultrasound-guided injection of embryos/the amniotic sac with DNA or RNA, with electroporation.
- Ultrasound-guided injection of post-natal mice.
- Electroporation of DNA-modifying agents
For questions regarding registration and booking, please find contact details below.
Clients who are affiliated with institutions outside Karolinska Institutet are welcome to contact us via email.