Unit of Molecular Toxicology
Our research aims to identify and characterize molecular and biochemical processes that are induced by exposure to toxic substances including engineered nanomaterials. We are also engaged in studies of the process of inflammation and in cancer research.
Inflammation research focuses on mechanisms of clearance of apoptotic cells (programmed cell clearance) and implications for the resolution of inflammation. We are also strongly engaged in research on congenital and acquired neutropenia and its underlying molecular mechanisms.
The nanotoxicological research focuses on the elucidation of mechanisms underlying toxicity of novel nanomaterials including carbon nanotubes and graphene as well as nanomaterials with potential biomedical applications, with a particular focus on hazardous effects on the immune system as well as on genotoxicity of nanomaterials and on potential endocrine disrupting effects.
Our research has a strong international dimension, with numerous international collaborations and participation in international research consortia funded by the European Commission through the Seventh Framework Program as well as the EU Flagship Project, GRAPHENE.
Research group leader
Foreign Adjunct Professors
- Professor Ding Xue, University of Colorado
- Professor Valerian Kagan, University of Pittsburgh
- Apoptosis and cell clearance: Molecular mechanisms and implications for human disease
- Molecular and clinical studies of severe congenital neutropenia or Kostmann disease
- Engineered nanomaterials: Toxicological studies and biomedical implications
- Seventh Framework of the European Commission
- Swedish Research Council
- Swedish Cancer Foundation
- Foundation for Strategic Environmental Research (MISTRA)
- Stockholm County Council (ALF project)
- Swedish Cancer and Allergy Foundation