Unit of Biochemical Toxicology
Our research is focused on cancer and endocrine disruption and involves mechanisms, risk assessment and prevention.
The objective of our research is to understand the connection between exposure to chemicals and health effects with focus on cancer and endocrine disruption. To understand the mechanisms behind these health effects we work with different cellular models and analysis of various databases. We also develop risk assessment methodologies. Other areas of interest are combined effects and gender differences. Progress within these areas will lead to improved risk assessment and development of prevention strategies.
Head of unit
Kristian Dreij
Associate ProfessorResearch group leaders
Kristian Dreij
Associate ProfessorAnnika Hanberg
ProfessorHanna Karlsson
Associate ProfessorUlla Stenius
ProfessorUnit members
Projects
Mechanisms and prevention
- A novel mechanism-based approach for assessment of developmental toxicity of endocrine disruptors
- Cancer risk associated with low dose silica exposure
- Gender differences in carcinogenesis
- Genotoxic evaluation in Bolivian populations exposed to mixtures of pesticides
- Interactions between PAHs in complex mixtures and cellular effects
- Toxicity of (nano)particles with a focus on genome instability
- Transcriptional mutagenesis and cellular effects
- Application of the Adverse Outcome Pathway concept and bioinformatics for mechanistic understanding of COVID-19
Risk assessment
- EU Partnership for the Assessment of Risks from Chemicals (PARC)
- Health risk assessment of Endocrine Disrupters – focus on bisphenol A and development of methodology
- Using text mining to aid cancer risk assessment
- Toward risk assessment without animals: Development of Adverse Outcome Pathways for lung cancer