Endocrine disruptors-molecular mechanisms and adverse effects

Course dates

Latest course was on September 17-21, 2018.

Course organiser

The course is organised by the Advanced International Training Programme in Health Risk Assessment at IMM in collaboration with the Doctoral programme Environmental Factors and Health (EFH) at Karolinska Institutet, course number 2934 and the Executive and Professional Education Office at Karolinska Institutet.

Course credits

The course corresponds to 1.5 ECTS credits.

Learning outcomes

After the completion of the course the student should be able to:

- Describe molecular mechanisms and potential adverse effects of endocrine disruptors

- Explain methodologies to study the mechanisms of endocrine disruptors

- Identify and discuss challenges in identification and study of endocrine disruptors

- Discuss implications of endocrine disruption for human health


Endocrine disruptors are defined as an exogenous substance or mixture that alters function(s) of the endocrine system and consequently causes adverse health effects in an intact organism, or its progeny, or (sub)populations. Endocrine disruptors act via hormone receptors and by altering hormone levels and have been implicated in several endocrine-related diseases.
The course will include molecular mechanisms of endocrine disruptors, from molecular initiating events to adverse effects. Current and emerging methodologies for identification and analysis of the endocrine disruptors will be addressed. Attention will be given to future challenges in endocrine disruptor research.

Teaching and learning activities

Teaching and learning activities include lectures, exercises and group assignments.

Course programme

The course programme for the previous course.

The course is intended for

PhD students and other participants from academia as well as participants from authorities and industry.

Course fee

The fee for participants from academia is 300 euro, from authorities 600 euro and from industry 900 euro, including VAT. Course fee includes course material and coffee breaks. Payment of course fee can only be accepted from the participant’s employer, not from individuals.

The participants must cover their costs for travel and accommodation.

Course application

Information on application procedure to the next course will be available later.

Course leaders

Johanna Zilliacus, Annika Hanberg and Anna Beronius, Institute of Environmental Medicine, Karolinska Institutet.


Johanna Zilliacus

Senior lecturer
C6 Institute of Environmental Medicine
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