Selected publications from the research group.

Selection of recent publications

Purification and properties of Escherichia coli dihydrofolate reductase.Bioengineered Pancreas-Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia.
BiochemistryAdv Sci (Weinh) 2022 

Purification and properties of Escherichia coli dihydrofolate reductase.Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development-Current State-of-the-Art and Future Perspectives.
BiochemistryPharmacol 2022

Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity.
Azzimato et al.
Gastroenterology 2021 

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Zhou et al.
Science Advances 2021 

JAK inhibitors: more than just glucocorticoids.
Stebbing & Lauschke, V.M.
New England Journal of Medicine 2021 

3D adipose tissue culture links the organotypic microenvironment to improved adipogenesis.
Shen et al.
Advanced Science 2021 

Janus kinase inhibition reduces SARS-CoV-2 liver infectivity and modulates host cell inflammatory responses to reduce morbidity and mortality.
Stebbing et al.
Science Advances 2020 

A 3D cell culture model identifies Wnt/β-catenin mediated inhibition of p53 as a critical step during human hepatocyte regeneration.
Oliva-Vilarnau et al.
Advanced Science 2020 

Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients.
Stebbing et al.
EMBO Molecular Medicine 2020 

Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance.
Azzimato et al.
Science Translational Medicine 2020 

Liver macrophages regulate metabolism independently of inflammation.
Morgantini et al.
Nature Metabolism 2019 

Modulation of phase-shift between Wnt and Notch-signaling oscillations controls mesoderm segmentation.
Sonnen et al.
Cell 2018 

Massive rearrangements of cellular miRNA signatures are key drivers of hepatocyte dedifferentiation.
Lauschke et al.
Hepatology 2016 

Scaling of embryonic patterning based on phase-gradient encoding.
Lauschke et al.
Nature 2013

Complete list of publications available here


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