Publications
Selected publications from the research group.
Selection of recent publications
Purification and properties of Escherichia coli dihydrofolate reductase.Bioengineered Pancreas-Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia.
Biochemistry Adv Sci (Weinh) 2022
Purification and properties of Escherichia coli dihydrofolate reductase.Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development-Current State-of-the-Art and Future Perspectives.
Biochemistry Pharmacol 2022
Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity.
Azzimato et al. Gastroenterology 2021
Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Zhou et al.
Science Advances 2021
JAK inhibitors: more than just glucocorticoids.
Stebbing & Lauschke, V.M.
New England Journal of Medicine 2021
3D adipose tissue culture links the organotypic microenvironment to improved adipogenesis.
Shen et al.
Advanced Science 2021
Janus kinase inhibition reduces SARS-CoV-2 liver infectivity and modulates host cell inflammatory responses to reduce morbidity and mortality.
Stebbing et al.
Science Advances 2020
A 3D cell culture model identifies Wnt/β-catenin mediated inhibition of p53 as a critical step during human hepatocyte regeneration.
Oliva-Vilarnau et al.
Advanced Science 2020
Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients.
Stebbing et al.
EMBO Molecular Medicine 2020
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance.
Azzimato et al.
Science Translational Medicine 2020
Liver macrophages regulate metabolism independently of inflammation.
Morgantini et al.
Nature Metabolism 2019
Modulation of phase-shift between Wnt and Notch-signaling oscillations controls mesoderm segmentation.
Sonnen et al.
Cell 2018
Massive rearrangements of cellular miRNA signatures are key drivers of hepatocyte dedifferentiation.
Lauschke et al.
Hepatology 2016
Scaling of embryonic patterning based on phase-gradient encoding.
Lauschke et al.
Nature 2013
Complete list of publications available here