Martin Ingvar's research group
We focus the science of the subjective health experience with a cognitive neuroscience and translational science approach. Health statistics demonstrate that half of the sick leave absence in Sweden may be ascribed to the subjective health axis.
Our vision is to develop comprehensive physiological/biomedical explanations to the subjective health experience and the mission is defined by the unmet medical needs in patients with a low subjective health experience/low self esteem or chronic pain.
Subjective experiences are regulated from the pre-frontal cortex and we study how the descending cortical control exerts influence on e.g. pain experience, emotional/cognitive regulation and inflammatory markers and in treatment intervention studies.
We have expertise in PET, MRI, in behavioral science incl. behavioral genetics. Our research results have had impact on the understanding of pain regulation, emotional regulation and decision-making.
- Regulation of empathy for pain of others
- Genetic markers for pain experience and transmittor specific pain relief
- Sensory mechanisms and fMRI imaging; a study in fibromyalgia patients
Attenuated beta rebound to proprioceptive afferent feedback in Parkinson's disease.
Vinding M, Tsitsi P, Piitulainen H, Waldthaler J, Jousmäki V, Ingvar M, et al
Sci Rep 2019 Feb;9(1):2604
The effect of a transient immune activation on subjective health perception in two placebo controlled randomised experiments.
Andreasson A, Karshikoff B, Lidberg L, Åkerstedt T, Ingvar M, Olgart Höglund C, et al
PLoS ONE 2019 ;14(3):e0212313
Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A [C]PBR28 PET study.
Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, et al
Brain Behav. Immun. 2018 02;68():146-157
Stepped care in primary care - guided self-help and face-to-face cognitive behavioural therapy for common mental disorders: a randomized controlled trial.
Salomonsson S, Santoft F, Lindsäter E, Ejeby K, Ljótsson B, Öst L, et al
Psychol Med 2018 07;48(10):1644-1654
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group.
Hibar D, Westlye L, Doan N, Jahanshad N, Cheung J, Ching C, et al
Mol. Psychiatry 2018 04;23(4):932-942